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LMITransactions&Report2014-15

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LMI Transactions and Report 2014 - 20<strong>15</strong><br />

battle for safety in anaesthesia had now been largely<br />

won and thought that is was time to take this further<br />

outside the operating theatre. He discussed preoperative<br />

assessment which tried to predict patients<br />

who may have poor surgical outcomes. He highlighted<br />

cardiopulmonary exercise testing, one area in which he<br />

was currently researching. He quoted a paper by<br />

Musallam K et al 3 which highlighted the incremental<br />

risk of anaemia with other comorbidities such as<br />

cardiac disease, COPD, renal impairment, all being<br />

associated with a higher mortality. Therefore, as<br />

Shander A et al 4 had highlighted, perioperative patient<br />

blood management is vital for good outcomes. This<br />

includes optimising haemopoiesis, minimising blood<br />

loss and bleeding and the improvement of tolerance<br />

of anaemia. He wondered how many of us have been<br />

presented with a patient on the day of surgery who<br />

had been inadequately optimised but we all felt the<br />

pressure to continue. Almost always we manage to<br />

get the patient through anaesthesia and surgery but<br />

the real problems seem to start a couple of days<br />

afterwards where inevitable consequences often<br />

become complications. Therefore individualised care<br />

must be the aim of pre-operative assessment.<br />

Professor Pearse then looked at the surgical event and<br />

highlighted the importance of checklists and the<br />

variable use of the WHO checklist across Europe. He<br />

spoke about other factors that may help to improve<br />

outcomes such as minimally invasive cardiac output<br />

measurements and the use of epidural anaesthesia. He<br />

thought that these were very important and<br />

anaesthetists in general were not very good at<br />

highlighting the necessity of putting their case across<br />

strongly for pieces of equipment or better nursing<br />

care.<br />

Professor Pearse discussed events occurring early after<br />

surgery and reminded the audience that acute organ<br />

injury can be a cause of long-term harm. This can<br />

include acute lung injury, sepsis-related myocardial<br />

injury and loss of muscle function. He quoted a paper<br />

Squadrone V et al 5 which showed that the early use of<br />

CPAP (Continuous Positive Airway Pressure) for the<br />

treatment of post-operative hypoxaemia can<br />

significantly reduce post-operative respiratory<br />

complications. He also highlighted the association<br />

between post-operative troponin levels and mortality.<br />

Post-operative rises in troponin were associated with<br />

a much higher mortality than similarly raised levels<br />

found in patients admitted through A&E.<br />

Professor Pearse went on to look at events later after<br />

surgery and showed a paper by Khuri et al 6 which<br />

demonstrated those with either pulmonary or wound<br />

complications had a significantly lower 5 and 10 year<br />

survival after surgery. This was again demonstrated for<br />

acute kidney injury after cardiac surgery 7 . Acute<br />

kidney injury was a key cause of chronic kidney disease<br />

as a result of loss of nephrons during each episode. He<br />

reminded the audience that the serum creatinine<br />

actually falls after surgery and therefore if it is raised,<br />

this is evidence of a much bigger injury than a rise<br />

associated with no surgery. Finally, he thought that<br />

anaesthetists should see some patients in postoperative<br />

clinics because they tend to be better at<br />

looking at the whole patient rather than just the<br />

outcome of surgery. They can then refer patients to<br />

relevant specialists if organ dysfunction has worsened<br />

as a result of these surgical episodes.<br />

Professor Pearse thought that surgery could often be a<br />

sentinel event with this being the first contact that<br />

many patients will have with a doctor. This can lead to<br />

the unmasking of many co-morbidities which often<br />

need to be treated prior to surgery and anaesthesia.<br />

He highlighted a number of quality improvement<br />

initiatives, such as the publication of performance data<br />

for individual surgeons and the way that cardiological<br />

services have been reorganised over the last 10 years<br />

showing a major improvement in 30 day survival<br />

following STEMI. He spoke about the EPOCH trial<br />

(Enhanced Perioperative Care for High Risk Patients)<br />

which is a project to implement an integrated care<br />

pathway for patients scheduled for emergency<br />

laparotomy. He described how healthcare can learn<br />

lessons from other industries and highlighted the way<br />

that the building of Crossrail in central London had<br />

changed building culture to greatly improve the safety<br />

of workers on the project.<br />

Finally he thought that the Royal College of<br />

Anaesthetists should be renamed that Royal College of<br />

Perioperative Medicine and reminded the audience<br />

that the College was soon to roll out its initiative in this<br />

area.<br />

1 Lancet 2008;372:139-44<br />

2 NEJM 2009;361:1368-75<br />

3 Lancet 2011;378:1396-407<br />

4 BJA 2012;109:55-68<br />

5 JAMA 2005:293;589-95<br />

6 Ann Surg 2005:242;326-343<br />

7 Hobson C et al, Circulation 2009:119;2444<br />

Ewen Forrest<br />

28

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