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Active Pharmaceutical Ingredient (API) Market Outlook, Demand, Key Manufacturers by 2025

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<strong>Active</strong> <strong>Pharmaceutical</strong> <strong>Ingredient</strong> (<strong>API</strong>) <strong>Market</strong> <strong>Outlook</strong>, <strong>Demand</strong>,<br />

<strong>Key</strong> <strong>Manufacturers</strong> <strong>by</strong> <strong>2025</strong><br />

“The global <strong>Active</strong> <strong>Pharmaceutical</strong> <strong>Ingredient</strong> (<strong>API</strong>) market size<br />

was worth at USD 134.2 billion in the year 2015 which is<br />

anticipated to reach a value of USD 239.8 billion <strong>by</strong> <strong>2025</strong>, with<br />

CAGR of 6.0%. Rising prevalence of chronic diseases such as<br />

neurological diseases.<br />

The global <strong>Active</strong> <strong>Pharmaceutical</strong> <strong>Ingredient</strong> (<strong>API</strong>) market size was worth at USD 134.2 billion in the year 2015<br />

which is anticipated to reach a value of USD 239.8 billion <strong>by</strong> <strong>2025</strong>, with CAGR of 6.0%. Rising prevalence of<br />

chronic diseases such as neurological diseases, cardiovascular diseases, can lead to the growth.<br />

The key drivers can be the rising demand of efficient and rapid acting drugs and introduction of innovative drug<br />

production facility. Major key players are choosing for outsourcing the product from the developing regions<br />

such as India, Brazil and China, which also anticipated to drive the market.<br />

In addition, pharmaceutical companies face tremendous loss in terms of revenue owing to the patent expiration<br />

of blockbuster drugs. Expiration of patent results in increasing focus for development of generic versions of the<br />

molecules. The R&D investment of the company are no longer valuable after patent expiration. Thus, the <strong>API</strong><br />

outsourcing trend in rising.<br />

Synthesis Type Insights<br />

Based on synthesis type, the market is categorized into synthetic and biotech. Various methods are adopted <strong>by</strong><br />

the manufacturing companies depending up on the complexity of the molecule required. Synthetic drugs are<br />

manufactured on the basis of organic chemistry in contrast to biotechnology based drugs, which are produced<br />

<strong>by</strong> utilizing molecular techniques. Further classification of biotech segment is recombinant proteins, monoclonal<br />

antibodies and vaccines.<br />

Request Sample Copy of this <strong>Market</strong> Research @<br />

https://www.millioninsights.com/industry-reports/active-pharmaceutical-ingredients-api-market/request-sample


In 2015, synthetic segment held the largest share. The key factors for the biotech <strong>API</strong>s segment growth are large<br />

R&D investment for new biosimilars, increasing demand for protein-based medicines, and rising focus of key<br />

manufacturers toward biological drugs.<br />

Manufacturer Type Insights<br />

Based on the type of manufacturer, it is categorized into outsourced or merchant or in-house or captive <strong>API</strong>s.<br />

According to market estimates, in 2015, in-house <strong>API</strong>s was the largest segment and outsourced <strong>API</strong>s are<br />

anticipated to be the fastest growing market.<br />

All pharmaceutical companies does not have separate unit for the formulation of <strong>API</strong>. This has led to rise in the<br />

outsourcing of the molecules from the production sites. The need of investment in expensive production<br />

processes is eliminated <strong>by</strong> the outsourcing.<br />

Browse Full Research Report @<br />

https://www.millioninsights.com/industry-reports/active-pharmaceutical-ingredients-api-market<br />

Type Insights<br />

Based on the type, <strong>API</strong>s are classified into innovative and generics. Branded products come under innovative<br />

type, whereas the generic drugs are the ones, which are available OTC (over the counter). Owing of high rate of<br />

prescription, high drug development initiatives, and high price, the innovative <strong>API</strong>s segment dominated in 2015.<br />

Generic segment is anticipated to be fastest-growing type, due to expirations of patents of various blockbuster<br />

drugs. Patent expirations of branded drugs have very serious negative impacts on the drug producers, as the<br />

companies face the tremendous loss after expiration. Hence the drug manufacturers prefer more generic drugs<br />

than the branded ones.<br />

Regional Insights<br />

In 2015, <strong>API</strong> market was dominated <strong>by</strong> the North America and is anticipated to retain its position in upcoming<br />

years owing to encouraging government initiatives for generic drug usage, rising R&D expenditure, and<br />

technological advancements in the drug manufacturing practices.


Asia Pacific is anticipated to be the region with fastest growth owing to the increasing availability of cheap and<br />

affordable labour. Hence, key major companies are setting up their <strong>API</strong> production plants in developing<br />

countries of Asia Pacific such as China and India.<br />

Competitive Insights<br />

One of the key manufacturers of the <strong>API</strong> (<strong>Active</strong> pharmaceutical ingredients) is Teva <strong>Pharmaceutical</strong>s Ltd. Some<br />

of the additional key players in this industry includes Boehringer Ingelheim GmbH, AbbVie, Inc., Merck & Co.,<br />

Inc. and Cipla, Inc., New molecule launches, collaborations, acquisitions, and regional expansions are some<br />

strategic initiatives taken <strong>by</strong> these <strong>Key</strong> players to retain their position.<br />

<strong>Market</strong> Segment:<br />

<strong>API</strong> Type of Synthesis <strong>Outlook</strong> (Revenue, USD Billion, 2014 - <strong>2025</strong>)<br />

• Biotech<br />

• Monoclonal antibodies<br />

• Recombinant proteins<br />

• Vaccines<br />

• Synthetic<br />

<strong>API</strong> Type of Manufacturer <strong>Outlook</strong> (Revenue, USD Billion, 2014 - <strong>2025</strong>)<br />

• Captive <strong>API</strong>s<br />

• Merchant <strong>API</strong>s<br />

<strong>API</strong> Type <strong>Outlook</strong> (Revenue, USD Billion, 2014 - <strong>2025</strong>)<br />

• Generic <strong>API</strong>s<br />

• Innovative <strong>API</strong>s<br />

<strong>API</strong> Application <strong>Outlook</strong> (Revenue, USD Billion, 2014 - <strong>2025</strong>)<br />

• Cardiovascular Disease<br />

• Oncology<br />

• CNS & Neurological Disorders<br />

• Orthopedic Disorders<br />

• Endocrinology<br />

• Pulmonology<br />

• Gastrointestinal Disorders<br />

• Nephrology<br />

• Ophthalmology


<strong>API</strong> Regional <strong>Outlook</strong> (Revenue, USD Billion, 2014 - <strong>2025</strong>)<br />

• North America<br />

• U.S.<br />

• Canada<br />

• Europe<br />

• Germany<br />

• UK<br />

• Asia Pacific<br />

• China<br />

• Japan<br />

• Latin America<br />

• Mexico<br />

• Brazil<br />

• MEA<br />

• South Africa<br />

See More Reports of this Category <strong>by</strong> Million Insights @<br />

https://www.millioninsights.com/industry/pharmaceuticals


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