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Autumn Rights Medical Guide 2019

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MENTAL HEALTH<br />

CLINICAL STAGING IN PSYCHIATRY<br />

Making Diagnosis Work for Research and Treatment<br />

Edited by Patrick D. McGorry<br />

University of Melbourne<br />

and Ian B. Hickie<br />

University of Sydney<br />

August <strong>2019</strong><br />

234 x 156 mm 206pp<br />

27 b/w illus. 8 colour<br />

illus. 6 tables<br />

978-1-108-71884-4 Paperback<br />

£44.99<br />

Psychiatric diagnosis is experiencing a crisis of confidence. Current<br />

approaches are outmoded, with reform desperately needed. Clinical staging<br />

is a solution to this crisis. Clinical staging addresses the limitations of current<br />

diagnostic systems by recognising the full continuum or trajectory of mental<br />

illness from asymptomatic to chronic illness. It acknowledges the overlap<br />

between mental health symptoms during early stages and directly links each<br />

stage to treatment and underlying cognitive, neurological and biological<br />

changes. This approach enhances chances of early identification, promotes the<br />

implementation of safer treatments, and increases opportunities to alter the<br />

negative trajectory of mental disorders. This book comprehensively describes<br />

the conceptual basis of clinical staging in psychiatry, details current progress<br />

in identifying biomarkers for each stage, and explores the implications of<br />

staging on treatment and health systems. This book provides a foundation for<br />

transformational reform in psychiatric diagnosis.<br />

WHY IT WILL SELL<br />

• Describes a superior alternative<br />

to traditional and outmoded<br />

diagnostic methods, enabling<br />

readers to understand the<br />

utility and applicability of<br />

staging to psychiatry and how<br />

it addresses current diagnostic<br />

limitations<br />

• Information is relevant to a<br />

broad range of mental health<br />

clinicians, researchers and<br />

students<br />

• Links diagnosis to treatment,<br />

making the information<br />

clinically meaningful<br />

CONTENTS<br />

List of contributors; Foreword; Acknowledgements; Part I. Conceptual and Strategic Issues: 1. Diagnosis<br />

without borders: a pluripotential approach to preventive intervention in emerging mental disorders; 2.<br />

Clinical staging and its potential to enhance mental health care; 3. Time for a change: a more dynamic<br />

perspective on psychopathology; 4. A moving target: how risk for mental disorder can be modelled in<br />

dynamic rather than static term; Part II. Progress with Clinical Staging: 5. The utility of clinical staging<br />

in youth mental health settings: neurobiological and longitudinal data from Sydney-based studies<br />

of transdiagnostic cohorts; 6. Neuroimaging and staging: do disparate mental illnesses have distinct<br />

neurobiological trajectories?; 7. Staging of cognition in psychiatric illness; 8. Neuroinflammation<br />

and staging; 9. Bioactive and inflammatory markers in emerging psychotic disorders; 10.<br />

Electroencephalography and staging; Part III. Novel Treatment Strategies: 11. Novel treatment strategies:<br />

biological; 12. Psychosocial interventions for youth mental health; Part IV. Translational Aspects: 13.<br />

Transforming cultures to enable stage-related care of mental ill health: a youth mental health challenge;<br />

14. The quest for clinical utility and construct validity in psychiatric diagnosis.<br />

ADDITIONAL INFORMATION<br />

Level: medical specialists/consultants, specialist medical trainees<br />

www.cambridge.org/rights<br />

foreignrights@cambridge.org<br />

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