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Autumn Rights Medical Guide 2019

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OBSTRETICS<br />

IN-VITRO FERTILIZATION<br />

Fourth edition<br />

Kay Elder<br />

Bourn Hall Clinic, Cambridge<br />

and Brian Dale<br />

Centre for Assisted Reproduction, Naples<br />

November <strong>2019</strong><br />

246 x 189 mm c.288pp<br />

104 colour illus. 18 tables<br />

978-1-108-44181-0 Paperback<br />

£49.99<br />

This extensively updated new edition provides an indispensable account of<br />

modern in-vitro fertilization practice, building upon the popularity of previous<br />

editions. The authors initially give a comprehensive review of the biology<br />

of human gametes and embryos, before outlining basic to advanced IVF<br />

techniques. New developments in practical techniques and understanding are<br />

discussed, including in-vitro maturation, vitrification, preservation of fertility<br />

for cancer patients, stem cell technology, preimplantation genetic testing,<br />

and the role of epigenetics and imprinting. The revised introduction also<br />

incorporates a ‘refresher’ study review of fundamental principles of cell and<br />

molecular biology, now updated with current knowledge of meiosis in human<br />

oocytes, embryo metabolism and basic principles of genome editing. With<br />

high-quality illustrations and extensive, up-to-date reading lists, it is a musthave<br />

textbook for trainee and practising embryologists, as well as clinicians<br />

who are interested in the scientific principles that underpin successful IVF.<br />

WHY IT WILL SELL<br />

• Covers the content of established M.Sc. courses in clinical embryology and<br />

the curriculum for Embryology Certification in Europe, making it an ideal<br />

text for theoretical study and exam preparation<br />

• An extensive body of knowledge is covered in an easily readable format,<br />

with a complete list of up-to-date references and high-quality illustrations<br />

• A unique combination of scientific textbook and practical guide<br />

NEW TO THIS EDITION<br />

• Chapters covering theoretical subjects have been updated with the latest<br />

information available from animal and human research in reproductive<br />

biology<br />

• Includes new practical techniques including vitrification, in vitro maturation<br />

of gametes, preservation of fertility for cancer patients and stem cell<br />

biology<br />

• The updated introduction includes a ‘refresher’ study review of fundamental<br />

principles in cell and molecular biology, updated with recent information<br />

regarding meiosis in human oocytes and basic principles of genome editing<br />

CONTENTS<br />

Preface; Acknowledgements; 1. Review of cell and<br />

molecular biology; 2. Endocrine control of reproduction:<br />

controlled ovarian hyperstimulation for ART; 3. Gametes<br />

and gametogenesis; 4. Sperm-oocyte interaction; 5. First<br />

stages of development; 6. Implantation and early stages<br />

of fetal development; 7. Stem cell biology; 8. The clinical<br />

in-vitro fertilization laboratory; 9. Quality management in<br />

the IVF laboratory; 10. Sperm and ART; 11. Oocyte retrieval<br />

and embryo culture; 12. Cryopreservation of gametes<br />

and embryos; 13. Micromanipulation techniques; 14.<br />

Preimplantation genetic diagnosis; 15. Epigenetics and<br />

assisted reproduction; Index.<br />

ADDITIONAL INFORMATION<br />

Level: medical specialists/consultants, specialist medical<br />

trainees<br />

www.cambridge.org/rights<br />

foreignrights@cambridge.org<br />

37<br />

Previous editions<br />

sold in Arabic,<br />

Russian and Turkish<br />

41583.indd 37 05/09/<strong>2019</strong> 10:12

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