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For advertising rates call 716.807.7729 Tidbits ® of Niagara Region<br />
Page 5<br />
REMARKABLE PEOPLE<br />
THE PICCARD FAMILY<br />
B & B BBQ<br />
“Come Get Some Que”<br />
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of<br />
it<br />
• Jules Piccard was a Swiss chemist born in<br />
1840. He made contributions to food chemistry.<br />
Jules Piccard was the father of twin sons Auguste<br />
and Jean Piccard.<br />
• Auguste Piccard was born in 1884. In 1930,<br />
he and Paul Kipfer ascended to a height of 9.8<br />
miles (16 k) in a balloon Auguste designed<br />
which had an airtight aluminum gondola so<br />
they would not pass out from lack of oxygen.<br />
They became the first humans to enter the<br />
stratosphere, and were the first to see the curvature<br />
of the Earth with their own eyes.<br />
• Auguste made 27 high altitude flights. He<br />
then realized he could apply the same technology<br />
towards creating a vessel that could descend<br />
into the ocean’s depths. He began building<br />
a bathyscaphe in 1937 but was interrupted<br />
by World War II. The work continued in 1945.<br />
After making a series of successful unmanned<br />
trips to great depths, he gave the craft to the<br />
French navy in 1950, where it was redesigned<br />
to carry a human. In 1954, it took a man safely<br />
down 13,701 ft. (4,176 m). Auguste and his son<br />
Jacques built a second bathyscaphe and together<br />
they dove to a record-breaking depth of<br />
10,335 ft (3,150 m) in 1953.<br />
• Jean Piccard worked to advance balloon technology<br />
along with his twin brother Auguste.<br />
Jean and his wife Jeanette made the first stratospheric<br />
flight through clouds in 1934, ascending<br />
to Did a height you hear of <strong>11</strong> about miles the (18 family km) in who a pressurized got stuck<br />
Peter Pan’s Flight for over 3 hours?<br />
gondola. He subsequently invented a window<br />
Apparently, their vehicle would nevernever<br />
that would land. not frost over during flights.<br />
that<br />
Later he created an electronic system for emptying<br />
ballast bags.<br />
• Jean Piccard’s wife Jeannette was the first licensed<br />
female balloon pilot in the U.S., and the<br />
first woman to fly to the stratosphere when she<br />
accompanied her husband in 1934. She piloted<br />
the balloon, travelling 300 miles (482 km) in 8<br />
hours. (continued on next page)<br />
RLOOTDOANWM<br />
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CBD Oil Can Interfere<br />
With Other Medications<br />
DEAR DR. ROACH: I am a 49-year-old woman who<br />
had a massive heart attack in April. My father died<br />
of a massive heart attack at 49. I have four stents in<br />
three arteries and am on Brilinta, low-dose aspirin,<br />
blood pressure medication, etc.<br />
I have essential tremor, first noticing the tremors in<br />
middle school. The tremor is in my hands, making<br />
writing nearly impossible, and I have head bobs. I<br />
have an internal tremor that never stops. A previous<br />
practitioner prescribed a month’s trial of beta blockers<br />
several years ago. I noticed no relief with the<br />
tremor but was physically ill for the first 30 minutes<br />
of the morning in the first two weeks. Recently, I<br />
found an online blog regarding essential tremor and<br />
CBD oil. Nearly all of the bloggers found some level<br />
of relief using this treatment.<br />
If I choose to try CBD oil to assist with my tremor, is<br />
there a risk of it interfering with my heart and blood<br />
pressure medications? -- M.M.<br />
ANSWER: Cannabidiol, or CBD, is a nonpsychoactive<br />
substance found in Cannabis, as opposed to tetrahydrocannabinol,<br />
or THC, the best-known psychoactive<br />
component.<br />
CBD is typically sold as an oil and has been receiving<br />
press as a potential treatment for a wide variety of<br />
medical issues. Many or most of these claims have no<br />
data to support them. Anecdotal reports, such as most<br />
blogs, are neither reliable nor scientific (and may or<br />
may not be true). There also is an issue with proving<br />
the dosage and purity of products said to contain CBD.<br />
(continued in next column)<br />
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However, in the case of essential tremor, there is some<br />
evidence: Studies in mice have shown benefit with<br />
CBD, although a single case report showed effectiveness<br />
of THC but not CBD in essential tremor. The<br />
issue of drug interactions is a significant one. CBD<br />
inhibits two powerful pathways the body uses to detoxify<br />
drugs, the CPY3A4 and CYP2D6 systems. This<br />
is a serious issue for you. Ticagrelor (Brilinta), an anticoagulant,<br />
is metabolized by CYP3A4, as are some of<br />
the statin drugs usually prescribed to people with heart<br />
blockages. The effect of the anticoagulant could be<br />
much higher than expected, leading to bleeding risk.<br />
Other commonly used heart medications are metabolized<br />
by CYP2D6, and the effect on these medications<br />
is unpredictable.<br />
I can’t recommend CBD products given the medications<br />
you are taking, but would suggest you consider<br />
alternative treatments. You may have read about deep<br />
brain stimulation and ultrasound, two powerful and<br />
effective treatments for people whose symptoms have<br />
not responded to standard treatments.<br />
***<br />
DEAR DR. ROACH: This question is for my husband.<br />
How safe is drinking tea while on warfarin?<br />
He has his INR checked monthly, and for the most<br />
part it stays between 2 and 3. He watches his vitamin<br />
K intake regularly. He has read conflicting stories of<br />
how tea interacts with warfarin by making the INR<br />
levels high. -- S.J.<br />
ANSWER: Tea comes in two major types: black tea,<br />
which is fermented, and green tea, which is not. Black<br />
tea has no known interactions with warfarin (Coumadin).<br />
Green tea contains small amounts of vitamin K,<br />
which could make the INR lower and the warfarin less<br />
effective. However, the effect is likely to be small.<br />
Further, if he drinks a consistent amount per day, his<br />
dose can be adjusted to reflect his vitamin K intake.<br />
Dr. Roach regrets that he is unable to answer individual<br />
letters, but will incorporate them in the column<br />
whenever possible. Readers may email questions to<br />
ToYourGoodHealth@med.cornell.edu.<br />
(c) 2019 North America Synd., Inc.<br />
All Rights Reserved<br />
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