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World <strong>Robotic</strong> Symposium 2011<br />

<strong>Trans</strong>oral <strong>Robotic</strong> <strong>Surgery</strong> (TORS)<br />

Loews Miami Beach Hotel<br />

Miami Beach, Florida<br />

June 27-28, 2011<br />

<strong>Trans</strong>-<strong>Oral</strong> <strong>Robotic</strong> <strong>Surgery</strong><br />

<strong>The</strong> <strong>Royal</strong> <strong>Adelaid</strong>e Hospital Experience<br />

SUREN KRISHNAN OAM, FRACS, MBBS (<strong>Adelaid</strong>e)<br />

CHAIRMAN,<br />

DEPARMENT OF OTORHINOLARYNGOLOGY, HEAD & NECK SURGERY,<br />

ROYAL ADELAIDE HOSPITAL,<br />

ADELAIDE,<br />

SOUTH AUSTRALIA.<br />

CLINICAL ASSOCIATE PROFESSOR OF SURGERY,<br />

UNIVERSITY OF ADELAIDE, SOUTH AUSTRALIA.<br />

VISITING PROFESSOR OF HEAD & NECK SURGERY,<br />

SUN YAT SEN UNIVERSITY, GUANGZHOU, CHINA.


ASOHNS 2012 Annual Scientific Meeting - <strong>Global</strong><br />

Perspectives<br />

<strong>Adelaid</strong>e 31 Mar - 4 Apr 2012.<br />

� International Keynote Speakers:<br />

� Professor Eric M. Genden, MD, FACS<br />

Professor of Otolaryngology/Head and Neck <strong>Surgery</strong> and Immunobiology, Mount Sinai School<br />

of Medicine, New York, USA<br />

� Professor Antony Narula, FRCS<br />

Consultant Otolaryngologist, St Mary's Hospital, London and Honorary Professor, Middlesex<br />

University, England<br />

� Professor Gerard O'Donoghue, FRCS<br />

Consultant Neuro-otologist, Queens Medical Centre, Nottingham and Professor of<br />

Otolaryngology, University of Nottingham, England<br />

� Professor Rodney J. Schlosser, MD FACS<br />

Professor and Director of Rhinology, Medical University of South Carolina, USA<br />

� Associate Professor Edward M. Weaver, MD MPH FACS<br />

Associate Professor of Otolaryngology/Head & Neck <strong>Surgery</strong>; Chief of Sleep <strong>Surgery</strong>,<br />

University of Washington, Seattle, Washington, USA


DEPARTMENT OF OTOLARYNGOLOGY,<br />

HEAD AND NECK SURGERY<br />

ROYAL ADELAIDE HOSPITAL<br />

• THE CONTRIBUTORS<br />

– ANSTEY GILES 1920s<br />

– THE LATE JEFF ROZENBILDS<br />

– THE LATE P.V. RAJAGOPALAN<br />

– RON GRISTWOOD<br />

– DAN HAINS<br />

– DARCY ECONOMOS<br />

• THE CURRENT DEPARTMENT<br />

– MICHAEL JAY<br />

– PROFESSOR P.J. WORMALD<br />

– GUY REES<br />

– MICHAEL SCHULTZ<br />

– SAM ARENA<br />

– STEVE FLOREANI<br />

– MICHAEL SWITAJEWSKI<br />

– MARK SCHEMBRI<br />

– SURESH RAJAPAKSA<br />

– IAN WONG<br />

THE ROYAL ADELAIDE HOSPITAL<br />

ADELAIDE<br />

SOUTH AUSTRALIA


HEAD & NECK CONSULTATIVE CLINIC<br />

ROYAL ADELAIDE HOSPITAL<br />

� RADIOLOGIST<br />

� STEVE CHRYSSIDIS (DAVID DONOVAN, DAN MADIGAN, ANDY WHYTE)<br />

� PATHOLOGIST<br />

� PETER BIGNOLD<br />

� RADIATION ONCOLOGISTS<br />

� M.BORG, M.PENNIMENT, D.ROOS, R.GOWDA<br />

� MEDICAL ONCOLOGISTS<br />

� A.TAYLOR, N. SINGHAL (M.BROWN, M.KEEFE, S.SELVA)<br />

� ORAL SURGEONS<br />

� A.GOSS, P.SAMBROOK, (R.JONES, P.DUKE, P.PIRGOUSIS)<br />

� PLASTICS & RECONSTRUCTIVE SURGEONS<br />

� Y. CAPLASH, R. COREN (T.EDWARDS,,J.KATSAROS)<br />

� GENERAL SURGEONS<br />

� B.COVENTRY, G.GILL<br />

� BREAST / ENDOCRINE SURGEONS<br />

� J.KOLLIAS, M.BOCHNER (P.MALYCHA)<br />

� OTOLARYNGOLOGIST, HEAD & NECK SURGEONS<br />

� S.KRISHNAN, G.REES, M.SWITAJEWSKI, S.ARENA<br />

� (DAN HAINS, DARCY ECONOMOS, JEFF ROZENBILDS)<br />

� SPEECH PATHOLOGISTS<br />

� R.BURNETT, H.BARON, J.BEATTY<br />

� SPECIAL NEEDS DENTISTRY<br />

� ELIZ COATS, S. LIBERALI, B. SCOPACASA<br />

� DIETITIAN<br />

� R. KURMIS (M.HERRIOT, D.CLEGHORN)<br />

� SOCIAL WORKERS


TRANS ORAL ROBOTIC SURGERY<br />

� Why TORS<br />

� <strong>The</strong> Journey<br />

� <strong>The</strong> <strong>Royal</strong> <strong>Adelaid</strong>e Hospital Experience<br />

� Some data<br />

� <strong>The</strong> Future


WHY TORS<br />

� TREATMENT TOXICITY<br />

� DYSPHAGIA<br />

� OSTEORADIONECROSIS<br />

� TUMOUR BIOLOGY V HOST BIOLOGY<br />

� HPV<br />

� TECHNOLOGY<br />

� VISUAL AND INSTRUMENT ACCESS<br />

� NO TREMOR<br />

� REDUCED MORBIDITY


WHY <strong>Trans</strong> <strong>Oral</strong> <strong>Robotic</strong> <strong>Surgery</strong> ?<br />

Challenges of <strong>Trans</strong> <strong>Oral</strong> Laser <strong>Surgery</strong><br />

with Microscope<br />

� Ergonomics<br />

� Counter-intuitive motion<br />

� Hand / eye alignment<br />

� Instrument tremor<br />

� Non-wristed instruments<br />

� 2-D vision<br />

� Straight Line Optics<br />

� Alignment of CO2 beam<br />

� Positioning and Repositioning<br />

� Learning curve


THE ADELAIDE JOURNEY


PICKARD FOUNDATION DONATION 2004


St John of God<br />

Subiaco, Perth<br />

2003<br />

2004<br />

2005<br />

2007<br />

da Vinci® Australia – 5 /New Zealand - 2<br />

St Vincent’s Private Hospital<br />

Sydney Mercy Ascot Hospital<br />

<strong>Royal</strong> <strong>Adelaid</strong>e Hospital<br />

Auckland<br />

<strong>Adelaid</strong>e<br />

Epworth Eastern Private Hospital<br />

Richmond, Melbourne<br />

Epworth Private Hospital<br />

Box Hill<br />

<strong>The</strong> Grace Hospital<br />

Tauranga


CNAHS ROBOTIC SURGERY COMMITTEE<br />

� DRAFT PROPOSAL<br />

� DEMONSTRATE A NEED<br />

� COST OF CURRENT PRACTICE<br />

� LENGTH OF STAY IN CURRENT PRACTICE<br />

� TRAINING IN ROBOTICS<br />

� MENTORING<br />

� DOCUMENTATION OF EVERY CASE<br />

� COST OF INSTRUMENTS<br />

� TIME OF SETUP<br />

� TIME OF SURGERY<br />

� BLOOD LOSS<br />

� ICU STAY<br />

� LENGTH OF STAY


ASOHNS A.S.M. ADELAIDE 2007


VISIT TO HOSPITAL UNIVERSITY PENNSYLVANIA,<br />

PHILADELPHIA<br />

FEBRUARY 2008<br />

Leviticus XXV:10, "Proclaim liberty<br />

throughout all the land, unto all the<br />

inhabitants thereof."


Professor Gregory Weinstein<br />

Deputy Chairman<br />

Otolaryngology and Head and Neck <strong>Surgery</strong><br />

Hospital of the University of Pennsylvania


Professor Bert O’Malley<br />

Chairman<br />

Otolaryngology and Head and Neck <strong>Surgery</strong><br />

Hospital of the University of Pennsylvania


HOSPITAL UNIVERSITY PENNSYLVANIA,<br />

PIG MODEL LABORATORY, PHILADELPHIA<br />

FEBRUARY 2008


VISIT TO AND ROBOTIC COURSE<br />

INTUITIVE LABORATORIES, SUNNYVALE,<br />

CALIFORNIA


VISIT TO AND CADAVERIC COURSE<br />

INTUITIVE LABORATORIES, SUNNYVALE,<br />

CALIFORNIA<br />

JULY 2008


RAH TRIAL RUN


Julie Bowd & Stuart Winter


J-C Hodge and David Howe


FK<br />

Boyle Davis


FK RETRACTOR - LARYNGEAL SURGERY


<strong>The</strong> Instruments


<strong>The</strong> Pre Resection Assessment<br />

SCOPE ACCESS<br />

TELESCOPY<br />

PALPATION<br />

NIELS KOKOT


Haemostasis<br />

MICROFRANCE<br />

LIGACLIP<br />

HAEMOSTASIS


LINGUAL ARTERY<br />

TITANIUM TOXICITY!


Haemostasis


KEYS TO SUCCESS<br />

� GOOD NURSE / TECHNICIAN<br />

� GOOD SURGICAL ASSISTANT<br />

� GOOD EXPOSURE<br />

� BOYLE – DAVIS GAG (for most procedures)<br />

� F-K RETRACTOR (for larynx)<br />

� WRISTED INSTRUMENTS WITH BIPOLAR<br />

� MICROLARYNGEAL CLIP APPLICATORS<br />

(GOOD SURGICAL ASSISTANT)


TRANS ORAL ROBOTIC SURGERY<br />

IN<br />

HEAD AND NECK CANCER<br />

THE ROYAL ADELAIDE HOSPITAL EXPERIENCE


TORS - RAH EXPERIENCE<br />

� 78 CASES<br />

� 48 OROPHARYNGEAL CANCERS<br />

� 4 PARAPHARYNGEAL SPACE TUMOURS<br />

� 4 SUPRAGLOTTIC LARYNGECTOMIES<br />

� 2 VERTICAL PARTIAL LARYNGECTOMIES<br />

� 16 SLEEP APNEA SURGERIES


TORS - VERTICAL PARTIAL LARYNGECTOMY<br />

en bloc technique


TORS - VERTICAL PARTIAL LARYNGECTOMY<br />

en bloc with laser


SUPRAGLOTTIC LARYNGECTOMY –<br />

en bloc technique


PARAPHARYNGEAL SPACE<br />

TUMOUR SURGERY<br />

CONTROLLED VISUAL ACCESS OF SUPERIOR LIMIT OF TUMOUR<br />

AVOID MORBIDITIES OF EXTERNAL ACCESS<br />

-FACIAL NERVE<br />

-SCAR<br />

-PAROTID SURGERY & FREY’S SYNDROME<br />

-FIRST BITE SYNDROME


PARAPHARYNGEAL SPACE<br />

TYPE IV SECOND BRANCHIAL ARCH CYST<br />

CONTROLLED ACCESS TO INFLAMMATORY, ADHERENT MASSES IN PPS


TRANS ORAL ROBOTIC SURGERY<br />

AT<br />

THE ROYAL ADELAIDE HOSPITAL<br />

IMAGE GUIDED RETRO PHARYNGEAL LYMPH NODE DISSECTION


OVERVIEW OF ADULT SNORING<br />

AND<br />

SLEEP APNOEA<br />

WORLD ROBOTIC SURGERY MEETING, ORLANDO, APRIL 2010<br />

Mr. Suren Krishnan O.A.M., F.R.A.C.S.<br />

Clinical Associate Professor of <strong>Surgery</strong><br />

University of <strong>Adelaid</strong>e<br />

Head of Department<br />

Otolaryngology, Head and Neck <strong>Surgery</strong><br />

<strong>Royal</strong> <strong>Adelaid</strong>e Hospital<br />

Mr. Sam Robinson F.R.A.C.S.<br />

Consultant Surgeon<br />

Flinders Medical Centre<br />

<strong>Adelaid</strong>e<br />

South Australia


VALE<br />

DR. SAMUEL ROBINSON<br />

1967 -2010


UPP technique<br />

Submucosal uvulopalatopharyngoplasty<br />

(Modified from Friedman M, Landsberg R, Tanyeri H.)<br />

Submucosal uvulopalatopharyngoplasty.<br />

Op Tech Otolaryngol Head Neck Surg 2000;11:26–9.)


Expansion sphincter pharyngoplasty<br />

K. Pang, T. Woodson


Palatal Advancement :<br />

<strong>The</strong> concept


Palatal advancement


Submucosal Lingualplasty<br />

� Robinson S, developed 2006. In press<br />

Atlas of snoring & sleep apnea surgery<br />

Ed; Friedman M, 2008.<br />

� Involves dissection in a plane just<br />

superficial to n-v bundles identified<br />

with U/S, then developing/protecting<br />

this plane with a malleable retractor<br />

� 15-25ml excised including muscle<br />

superficial & lateral to n-v bundles.<br />

Minor pain.<br />

� Outcomes study ongoing.


Submucosal Lingualplasty


TORS – TONGUE BASE AND<br />

OROPHARYNX RESECTIONS


� ABSTRACT<br />

�<br />

<strong>Trans</strong>oral Lateral Oropharyngectomy<br />

for Squamous Cell Carcinoma of the Tonsillar Region<br />

I. Technique, Complications, and Functional Results<br />

F. Christopher Holsinger, MD; Andrew J. McWhorter, MD; Madeleine Ménard, MD;<br />

Dominique Garcia, MD; Ollivier Laccourreye, MD<br />

Arch Otolaryngol Head Neck Surg. 2005;131:583-591.<br />

Objectives To describe the surgical technique for transoral lateral oropharyngectomy (TLO) and its safety, postoperative<br />

management, complications, and functional outcomes.<br />

� Design A 20-year retrospective case series review. Mean follow-up was 10 years. All but 10 patients were followed up<br />

until the fifth postoperative year or death.<br />

� Setting Academic, tertiary referral center.<br />

� Patients A total of 191 patients who underwent TLO for selected invasive squamous cell carcinoma of the tonsil and/or<br />

tonsillar fossa.<br />

� Interventions Ten patients had received preoperative radiation therapy. Induction chemotherapy was used in 153 patients<br />

(80.3%). An associated neck dissection was performed in 148 patients (77.5%). Postoperative radiation therapy was<br />

administered to 52 patients (28.7%).<br />

� Main Outcome Measures Overall survival rate, intraoperative mortality, and perioperative mortality were determined.<br />

<strong>The</strong> need for and length of nasogastric tube feeding and tracheotomy were calculated. <strong>The</strong> incidence of significant<br />

postoperative surgical and medical complications was recorded.<br />

� Results No intraoperative mortality occurred, but 5 patients (2.6%) died in the immediate postoperative period, 3 from<br />

medical complications and 2 from unknown causes. In this series, the internal carotid artery was never injured, and no<br />

cutaneous-oropharyngeal fistulas were apparent. <strong>The</strong> incidence of significant surgical complications from the oropharynx<br />

was 6.3%. Nasopharyngeal reflux and severe rhinolalia were the most common complications, occurring in 9 patients.<br />

Increasing tobacco use was statistically correlated with an increase in postoperative pneumonia from aspiration (P = .05)<br />

but no surgical complications. Seven patients (3.7%) had a temporary tracheotomy for a mean of 5 days. One hundred<br />

twelve patients (58.6%) had a nasogastric tube inserted for a mean of 6 days. No patients had a permanent gastrostomy or<br />

tracheotomy tube. <strong>The</strong> mean duration of hospitalization was 9 days. <strong>The</strong> duration of hospitalization was statistically<br />

correlated with the need for nasogastric tube placement and its duration (P


<strong>Trans</strong> <strong>Oral</strong><br />

Lateral Oropharyngectomy


Structures identified during dissection


Resection Complete<br />

1) SUTURE POSTERIOR PHARYNGEAL WALL TO POSTERIOR LIP<br />

(NASAL SURFACE) OF REMNANT UVULA<br />

(2) INJECT BOTOX INTO REMINING PALATAL MUSCULATURE<br />

(3) PATIENT HAS NGT FOR 3 OR 4 DAYS AND DISCHARGED<br />

HOME WHENSWALLOWS SAFELY


TRANS ORAL ROBOTIC SURGERY<br />

AT<br />

THE ROYAL ADELAIDE HOSPITAL


TORS - RAH EXPERIENCE<br />

� 48 preliminary analysis<br />

ROBOTIC PATIENTS BY CANCER STAGING<br />

10%<br />

63%<br />

20%<br />

7%<br />

I<br />

II<br />

III<br />

IV


MONTHS POST-SURGERY<br />

30<br />

23<br />

15<br />

8<br />

0<br />

POST-TREATMENT RECURRENCE BY SITE<br />

1 2 3 4<br />

INDIVIDUAL PATIENTS<br />

ALL 4 LOCAL RECURRENCES WERE PALLIATIVE RESECTIONS<br />

LOCAL<br />

NECK<br />

DISTANT<br />

( 2 RECURRENCES AFTER R/T, 2 LARGE T4s ALL<br />

RESECTIONS FOR SYMPTOM RELIEF)<br />

ONE T1N1 PATIENT DEVELOPED METASTASES


MONTHS POST ROBOTIC SURGERY<br />

30<br />

23<br />

15<br />

8<br />

0<br />

SURVIVAL TIME BY T STAGE FOR DECEASED<br />

T1N2B T1N2 T2N2B T2N2C T4aM0<br />

T STAGE


CURRENT REMISSION POST ROBOTIC SURGERY BY CANCER STAGE<br />

MONTHS POST ROBOTIC SURGERY<br />

MONTHS POST ROBOTIC SURGERY<br />

30<br />

23<br />

15<br />

30<br />

23<br />

15<br />

8<br />

0<br />

8<br />

0<br />

1 2 3 4 5 6 7 8 9 1011121314151617181920212223242526<br />

INDIVIUAL PATIENTS<br />

I (n = 4)<br />

II (n = 8)<br />

III (n = 3)<br />

IV (n = 26)<br />

RECURRENCES POST ROBOTIC SURGERY BY TN STAGE<br />

Tis N0 T2N0 T1N2B TXN2B T2N2B T2N2C T4aN0<br />

TN STAGE<br />

CURRENT LENGTHS OF REMISSION POST ROBOTIC SURGERY BY N STAGE<br />

MONTHS SINCE ROBOTIC SURGERY<br />

30<br />

23<br />

15<br />

8<br />

0<br />

CURRENT LENGTHS OF REMISSION POST ROBOTIC SURGERY BY T STAGE<br />

MONTHS POST ROBOTIC SURGERY<br />

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15<br />

30<br />

23<br />

15<br />

8<br />

0<br />

INDIVIDUAL PATIENTS<br />

1 2 3 4 5 6 7 8 9 10 11 1213141516171819202122<br />

INDIVIDUAL PATIENTS<br />

N0<br />

N1<br />

N2A<br />

N2B<br />

N2C<br />

N3<br />

T0 (n = 1)<br />

Tis (n = 1)<br />

T1(n = 11)<br />

T2 (n = 22)<br />

T3 (n = 4)<br />

T4a (n = 3)<br />

TX (n = 1)


TORS - RAH EXPERIENCE<br />

� Data on 15 cases from first 12 months presented<br />

� 15 Cancers<br />

� 11 Male<br />

� 4 Female<br />

� Average Age 53.6 years


TORS - RAH EXPERIENCE<br />

CASE MIX<br />

� 3 <strong>Oral</strong> Cavity<br />

� 8 Oropharynx<br />

� 4 Larynx<br />

� 2 Vertical Partial Laryngectomy<br />

� 2 Supraglottic Laryngectomy


TORS - RAH EXPERIENCE<br />

STAGE OF DISEASE<br />

AJCC<br />

� 4 Stage I<br />

� 4 Stage II<br />

� 1 Stage III<br />

� 6 Stage IV<br />

UICC T Stage<br />

� 8 T1<br />

� 7 T2<br />

UICC N Stage<br />

� 8 N0<br />

� 1 N1<br />

� 6 N2


TORS - RAH EXPERIENCE<br />

OPERATIVE EVENTS<br />

� Robot Setup Time average - 34.5 minutes<br />

� Operation Time average - 50 minutes<br />

� Radical Tonsil Tumour Excision - 27 minutes<br />

� W L E of Tongue Base with Buccinator Myomucosal flap inset - 105 minutes<br />

MARGINS<br />

� 9 Clear<br />

� 2 Positive<br />

� 2 No Cancer (previous excisional biopsy)<br />

� 2 Doubtful (Piecemeal Supraglottic Resections)<br />

NECK DISSECTIONS<br />

� At same sitting<br />

� At 2 weeks post TORS<br />

RECONSTRUCTIONS<br />

� Healing by secondary intention<br />

� <strong>Robotic</strong> Buccinator and FAMM Flap<br />

� Open Nasolabial Flap


TORS - RAH EXPERIENCE<br />

POST-OPERATIVE EVENTS<br />

HOSPITAL STAY<br />

� 3 to 6 days<br />

� Limited by recovery from neck dissection<br />

COMPLICATIONS<br />

� 0 Intra-operative<br />

� 5 Early Post-operative<br />

� 3 Pneumonia<br />

� 1 Chyle leak<br />

� 1 Volvulus<br />

DYSARTHRIA<br />

� 1 Tethered by Buccinator Flap until Flap divided<br />

SWALLOWING<br />

� 11 <strong>Oral</strong> Intake after Day 3<br />

� 1 PEG dependent for 6 months (Patient with 3 rd primary UADT SCC)<br />

� 1 PEG supplement<br />

� 1 PEG dependent after Post-operative Radiotherapy<br />

� 1 PEG dependent after CRT<br />

FOLLOW UP<br />

� Longest 12 months<br />

� 12 Free of disease


KEYS TO SUCCESS IN TORS<br />

� GOOD TRAINING<br />

� EXPERIENCE WITH TRANS ORAL LASER SURGERY<br />

� GOOD NURSE / TECHNICIAN<br />

� GOOD SURGICAL ASSISTANT<br />

� GOOD EXPOSURE<br />

� BOYLE – DAVIS GAG<br />

� F-K RETRACTOR<br />

� OBSSESSIVE HAEMOSTASIS<br />

� WRISTED INSTRUMENTS WITH BIPOLAR<br />

� MICROLARYNGEAL CLIP APPLICATORS


TORS - SUMMARY<br />

� This is a new surgical technique & offers another option for patients<br />

� Better visualisation<br />

� More accurate tissue resection<br />

� Potential to reduce tissue trauma<br />

� Surgeon OHW&S<br />

� Ergonomics<br />

� Posture<br />

� Fatigue<br />

� Disadvantages<br />

� No true haptic feedback<br />

� Cost<br />

� Each case is currently treated as a research outcome evaluation<br />

� Accumulation of case experience<br />

� Reporting of cases<br />

� Assessment of outcomes of function, quality of life and costs<br />

� Establishment of National and International database


THE FUTURE


� Our legions are brimful, our cause is ripe;<br />

<strong>The</strong> enemy increaseth every day; We,<br />

at the height, are ready to decline.<br />

� <strong>The</strong>re is a tide in the affairs of men<br />

Which taken at the flood, leads on to fortune;<br />

Omitted, all the voyage of their life<br />

Is bound in shallows and in miseries.<br />

� Shakespeare , Julius Caesar(4.3.218)<br />

VALE<br />

CHRIS O’BRIEN AO, PhD, MS, FRACS<br />

January 1952 - June 2009

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