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CURRICULUM VITAE FOR DR BENJAMIN P TURNER Consultant ...

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<strong>CURRICULUM</strong> <strong>VITAE</strong> <strong>FOR</strong><br />

<strong>DR</strong> <strong>BENJAMIN</strong> P <strong>TURNER</strong><br />

<strong>Consultant</strong> and Honorary Senior Lecturer in Neurology<br />

Barts and The London NHS Trust<br />

The London Bridge & HCA Hospitals<br />

Personal Date of Birth 7 January 1967<br />

Nationality British<br />

Status Single<br />

Education St Mary's Hospital Medical School, London<br />

St Paul's School, Barnes, London<br />

Qualifications DM 2003<br />

MRCP 1996<br />

MBBS 1991<br />

Membership GMC 3591284<br />

MDU 270730G<br />

Association of British Neurologists<br />

American Academy of Neurology<br />

British Medical Association


Key Skills and Achievements:<br />

Clinical Training<br />

Management<br />

My House Officer posts exposed me to the full range of medical and surgical<br />

emergencies.<br />

As a Senior House Officer in busy District General and Teaching Hospitals, I worked in<br />

a wide spectrum of general medical specialities. I performed two years of acute medical<br />

on-calls on a 1:4 rota and attended clinics in all specialities. In addition I dealt with<br />

Paediatric and Gynaecological emergencies while working in casualty. I was a Senior<br />

House officer in Neurology at Sunderland, Newcastle and lastly Sheffield where I was on<br />

the registrar rota for one year. The on-calls covered the region and I was therefore<br />

exposed to the full range of neurological emergencies and was in charge of their acute<br />

management. I learnt and performed investigative and therapeutic procedures including<br />

lumbar punctures, muscle biopsies, ‘tensilon’ testing and apomorphine challenge tests.<br />

I performed clinical duties throughout my research and did my SpR training in<br />

Nottingham. I have worked with all the consultants based at the Queen’s Medical Centre,<br />

Nottingham doing both general and specialist neurology clinics and a 1 in 6 neurology<br />

‘on-call’ rota. Specialist clinics that I regularly attended included epilepsy, movement<br />

disorders and dementia, neuro-ophthalmology, multiple sclerosis, neuro-immunology,<br />

nerve and muscle and motor neurone disease. I performed monthly botulinum toxin<br />

clinics. The neurology department worked closely with the neurosurgeons and<br />

neuroradiologist, sharing meetings and I have observed surgical procedures in theatre. I<br />

also regularly attended neurophysiology sessions for one to one teaching. I have been<br />

able to participate in ancillary clinics such as ophthalmology, neuro-pyschiatry, neurorehablitation<br />

and neuro-otology.<br />

I was Locum <strong>Consultant</strong> Neurologist at QMC from November 2002 to April 2003, with a<br />

particular view to instigating the Risk Sharing Scheme for MS.<br />

Attended non-clinical professional development for specialist registrars<br />

‘Managing Trainees’ and ‘Supporting Trainees.’<br />

<strong>Consultant</strong> Management Induction at Barts and the London<br />

Appraisal and Assessment workshop Barts and the London<br />

Education and Audit<br />

Elected as the Secretary for the Association of British Neurologist (ABN) Trainees and<br />

thereby sat, as the trainees observer, on the Royal College of Physicians Specialist<br />

Advisory Committee in Neurology and the ABN Training and Education Subcommittee<br />

(TESC). This has given me a privileged insight into the strengths and weaknesses of<br />

neurological training. The last year was particularly challenging with the need to develop<br />

a new curriculum and assessment tools robust and transparent enough to satisfy the STA<br />

and JCHMT.<br />

Whilst on TESC I have written the Calman training questionnaire and I have submitted<br />

and reviewed questions for the ABN self-assessment exercise.


I was one the founder members of the Neurology SpR national training weekend, an<br />

annual event. This has been running successfully for five years, providing a forum for<br />

registrars to present their research to their peers, along with lectures in clinical and basic<br />

science topics.<br />

Throughout my training I have attended weekly consultant led neurology teaching<br />

sessions and general medical meetings, at which I have regularly presented clinical topics<br />

such as cerebral abscess, Lambert-Eaton syndrome and status epilepticus. As a consultant<br />

I now chair the weekly Clinical Neurological/Neurosurgical Meetings and attend the<br />

weekly General Medical meetings.<br />

Audit performed throughout my career, most recently “Audit of the Use of<br />

Immunoglobulins in Guillain-Barre at QMC.” and ‘BIH, management of.’ ‘In-patient<br />

referrals’<br />

Regular teaching of junior doctors and students, including speaking and examining on<br />

courses for anaesthetists and ophthalmologist.<br />

Attended a postgraduate course ‘Small group and tutorial teaching’ at the University of<br />

Nottingham<br />

Courses and meetings attended in last 5 years<br />

ABN/ Exeter 2000<br />

International Congress of Parkinson’s and Movement disorders/Barcelona 2000<br />

ABN/ London ABN trainees meeting & courses 2000<br />

Northern Neuroimmunology Interest Group/Manchester 2000<br />

Advanced Clinical Neurology Course/Edinburgh 2001<br />

Neuroimmunology/Queen’s Square/London 2001<br />

Stroke/Queen’s Square 2001<br />

World Congress of Neurology/London 2001<br />

Cannabis Investigators meeting and induction/Birmingham 2001<br />

ABNT/Coventry ABN trainees meeting and course 2001<br />

American Academy of Neurology, Denver 2002<br />

SpR Training days/ Nottingham/Sheffield/Leicester 1997-2002<br />

American Academy of Neurology, Hawaii 2003<br />

ECTRIMS, Milan 2003<br />

ABN, London 2004<br />

American Academy of Neurology, San Francisco 2004<br />

Stroke Therapy, Royal College of Physicians<br />

2004<br />

Cambridge Dementia Course, Cambridge 2004<br />

American Academy of Neurology, Miami 2005


Appointments<br />

Current Appointment<br />

<strong>Consultant</strong> Neurologist and Honorary Senior Lecturer, Barts and The London Trust.<br />

Previous Appointments<br />

Locum <strong>Consultant</strong> Queen’s Medical Centre, November 2002-April 2003<br />

SpR Training University Hospital, Queen’s Medical Centre, Nottingham,<br />

January 1999 – November 2002<br />

Research Neurology research registrar January 1997-January 1999<br />

University of Nottingham, Nottingham<br />

Supervisor: Professor L D Blumhardt / Dr CS Constantinescu<br />

Neurology Senior House Officer February 1996-December 1996<br />

Royal Hallamshire Hospital, Sheffield<br />

<strong>Consultant</strong>s: Professor H J Sagar/Dr G A B Davies-Jones/Dr G S<br />

Venables/Dr S J L Howell/Dr R A Grunewald<br />

Ophthalmology Senior House Officer August 1995-February 1996<br />

Eye Infirmary, Sunderland<br />

Rheumatology/ Senior House Officer March 1995-July 1995<br />

General Medicine Freeman Hospital, Newcastle<br />

Neurology Senior House Officer February 1995-March 1995<br />

Newcastle General Hospital<br />

<strong>Consultant</strong>s: Dr P Hudgson/Dr T Walls<br />

Neurology/ Senior House Officer August 1994-February 1995<br />

General Medicine District General Hospital, Sunderland<br />

<strong>Consultant</strong>s: Dr P G Cleland/Dr R E Jones<br />

Nephrology/ Senior House Officer February 1994- July 1994<br />

General Medicine Royal Infirmary, Sunderland<br />

Respiratory/ Senior House Officer August 1993- January 1994<br />

General Medicine Royal Infirmary, Sunderland<br />

Accident and Senior House Officer February 1993- July 1993<br />

Emergency Central Middlesex Hospital, London<br />

General Surgery/ House Officer February 1992- August 1992<br />

Cardiothoracic St Mary's Hospital, London<br />

General Medicine House Office August 1991- February 1992


Research<br />

Hillingdon Hospital, Middlesex, London<br />

In July of 2003 I was awarded my MD for my thesis ‘Brain atrophy in multiple<br />

sclerosis’. This involved the development of a novel image analysis methods to estimate<br />

the volume change on magnetic resonance images and the application of these techniques<br />

multiple sclerosis patients and controls. This has resulted in three peer review article. I<br />

have collaborated with my neurosurgical colleagues and applied methods of ventricular<br />

measurement to study the outcome of different surgical procedures for hydrocephalus. I<br />

am interested in the neurological implications of Coeliac disease and have investigated<br />

patients with dermatitis herpetiformis for evidence of neurological disease and<br />

immunological markers, resulting in a peer review publication.<br />

Whilst a research registrar I participated in several multi-national, multi-centre<br />

randomised placebo controlled trials, organising the trials locally and recruiting patients<br />

in Nottingham. Trials include, Glatiramer acetate (TEVA), interferon-β 1a<br />

(PRISMS/Serono), ATM-027 (ASTRA) in relapsing and remitting multiple sclerosis.<br />

Interferon-β 1a (SPECTRIMS) and IVIG in secondary progressive (BAYER). I helped to<br />

run the national CAMS (Cannabis) trial in Nottingham.<br />

At The Royal London I continue to run clinical trials for patients with MS and I am the<br />

UK Principal Investigator for an international, multi-centre trial of Rebif versus<br />

Copaxone in RRMS. I am currently overseeing trials in Tysbari and over novel antiinflammatory<br />

drugs in MS.<br />

I have recently appointed a research registrar and in collaboration with the Department of<br />

Pathology we are studying neurodegeneration in MS.


Publications<br />

Dayan M. Turner B. McGhee C. Acute angle closure glaucoma masquerading as systemic<br />

illness. BMJ 1996; 313(7054): 413-5.<br />

Turner B, Wills AJ. Cerebral infarction complicating intravenous immunoglobulin therapy in<br />

a patient with Miller Fisher syndrome. J Neurol Neurosurg Psychiatry 2000; 68: 790-1.<br />

Tattersall R, Turner B. Brown-Sequard and his syndrome. Lancet 2000; 356: 61-3.<br />

Turner B, Wills AJ. Intravenous immunoglobulin causing reversible postleukoencephalopthy<br />

syndrome? J Neurol Neurosurg Psychiatry 2000; 69: 704.<br />

Turner B, Ramli N, Jaspan T, Blumhardt LD. Ventricular enlargement in multiple sclerosis: a<br />

comparison of linear and three dimensional MRI estimates. Neuroradiology 2001; 43(8):<br />

608-14.<br />

Wilson M, Morgan PS, Lin X, Turner B, Blumhardt LD. Quantitative diffusion weighted<br />

magnetic resonance imaging, cerebral atrophy and disability in multiple sclerosis. J Neurol<br />

Neurosurg Psychiatry 2001; 70: 318-22.<br />

Wills AJ, Turner B, Unsworth J, Fry L. Dermatitis herpetiformis, coeliac disease and<br />

neurological dysfunction. J Neurol Neurosurg Psychiatry 2001: 72(2): 259-261.<br />

Buxton N, Turner B, Ramli N, Vloeberghs M. Changes in third ventricular size with<br />

neuroendoscopic third ventriculostomy: a blinded study. J Neurol Neurosurg Psychiatry 2001;<br />

72(3): 385-7.<br />

Turner B, Wills AJ. Superficial siderosis associated with anterior horn cell dysfunction. J Neurol<br />

Neurosurg Psychiatry 2002: 72(2): 274-5<br />

Turner B, Lin X, Calmon G, Roberts N, Blumhardt LD. Cerebral atrophy and disability in<br />

relapsing-remitting and secondary progressive multiple sclerosis over 4 years. Multiple<br />

Sclerosis 2003; 9: 21-7.<br />

Lin X, Tench C R, Turner B, Blumhardt L D, Constantinescu C S. Spinal cord atrophy and<br />

disability in multiple sclerosis over four years: application of a reproducible automated<br />

technique in monitoring disease progression in a cohort of the interferon ß-1a (Rebif)<br />

treatment trial. J Neurol Neurosurg Psychiatry 2003; 74: 1090-1094.<br />

Everett C M, Dhillon H, Samarasinghe D, Berry L, Warwick S, Turner B. A Case of Cerebral<br />

Nocardiosis Following Brief Immunosuppression. European Journal of Neurology 2005.


Abstracts<br />

Turner B, Liu C, Edwards S, Gong Q, Roberts N, Blumhardt LD. Correlations of hypointense<br />

T1 lesions with cerebral volumes in multiple sclerosis. Journal of Neurology 1998; 245 :441.<br />

Turner B, Calmon G, Roberts N, Blumhardt LD. Cerebral atrophy and disability in multiple<br />

sclerosis: a four-year serial MRI study. Journal of Neurology 1999; 246: I/22.<br />

Turner B, N Ramli, T Jaspan, L D Blumhardt. Ventricular volumes in multiple sclerosis:<br />

which linear measures correlate best with 3D volumes and clinical parameters ? Journal of<br />

Neurology 1999; 246: I/64.<br />

Turner B, Ramli N, Jaspan T, Blumhardt LD. 2D and 3D measurements of ventricular size in<br />

multiple sclerosis: cross-sectional and serial studies. Multiple Sclerosis. 1999; 5: P215<br />

Turner B, Calmon G, Roberts N, Blumhardt LD. A four-year study of cerebral atrophy,<br />

ventricular enlargement and disability in multiple sclerosis. Multiple Sclerosis 1999; 5: P223.<br />

Lin X, Turner BP, Blumhardt LD. Ventricular enlargement and brain atrophy in multiple<br />

sclerosis: A serial MRI study. Journal of Neurology 2000; 247 (Suppl. 3): 39-40.<br />

Turner B, Pelosi L, Blumhardt LD. Localised, temperature-sensitive weakness in peripheral<br />

motor neuropathy. Journal of Neurology 2000; 247 (Suppl. 3): 147.<br />

Barkhof, F, Arfors L, Blumhardt LD, Olsson T, Landtblom AM, Fagius J, Hillert J, Turner B,<br />

Killestein J, Redmond I, Polman CH. MRI effects in MS patients after selective suppression<br />

of VB5.2/5.3 T cells. Revue Neurologique 2000; 156: 3S41.<br />

Turner B, Lennox G, Pelosi L, Lowe J. Corticobasal degeneration and amyotrophic lateral<br />

sclerosis, overlap in the lobar atrophies. Movement Disorders 2000; 15 (Suppl. 3): S226.<br />

Tengah C, Unsworth DJ, Fry L, Turner B, Wills AJ. Dermatitis herpetiformis, coeliac disease<br />

and neurological dysfunction. Journal of Neurological Sciences 2001;187 (Suppl. 1); S492.<br />

Turner B, Constantinescu CS, Powell RJ. Infliximab in the treatment of CNS vasculitis with<br />

uveitis. Neurology 2002; 58 (Suppl. 3): P06.080.<br />

Lin X, Turner B, Constantinescu C, Blumhardt LD, Fazekas F, Filippi M, Comi G, Maas<br />

enriquez M, Hommes OR and the European study on IVIG in Multiple Sclerosis (ESIMS).<br />

Cerebral volume change in secondary progressive multiple sclerosis: effect of intravenous<br />

immunoglobulins (IVIG) ENS 2002<br />

Turner B, Vaithianathar L, Tench CR, Morgan PS, Lin X, Constantinescu CS. Third ventricle<br />

volume: a surrogate marker for disability and disease burden in multiple sclerosis. ENS 2002


Talks<br />

‘Treatment developments in multiple sclerosis’<br />

Trent region MS society, Nottingham, 1998.<br />

‘Optic neuritis; implications of early treatment of multiple sclerosis’<br />

South Yorkshire regional Ophthalmology meeting, Royal Hallamshire Hospital,<br />

Sheffield, 1998.<br />

‘Disease modifying therapy and cerebral atrophy in multiple sclerosis’<br />

West and East Sussex Neuroscience meeting, Princess Royal Hospital, Haywards Heath,<br />

1999.<br />

‘Axonal loss and cerebral atrophy in multiple sclerosis’<br />

Northwestern Neuroscience meeting, Hope Hospital, Manchester 2000.<br />

‘Does Education improve compliance in DMT MS patients ?’<br />

Biogen Meeting, Edinburgh, 2005.<br />

‘Developments in MS’<br />

MS society, Wanstead, Essex, 2005.<br />

Chairman for National MS nurse convention, Coventry, March 2004<br />

Chairman for Essex MS group, a regional group of clinicians and MS nurses who meet<br />

bi-monthly.<br />

Interests<br />

Sport: windsurfing, tennis, skiing, snowboarding, rowing (1st 8 at St Paul's),<br />

motorcycles. Travelled extensively in South, Central and North America, Jamaica,<br />

Russia. Worked in Cameroon on elective and in a leper colony in Thailand.

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