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Angelo Mosso's Circulation of Blood in the Human Brain
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business account Hardcover: 240 pages Publisher: Oxford University Press; Translation edition (October 15,
2014) Language: English ISBN-10: 0199358982 ISBN-13: 978-0199358984 Product Dimensions: 9.4 x 0.8
x 6.4 inches Shipping Weight: 1.2 pounds (View shipping rates and policies)
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Book Description
Modern brain imaging is revolutionizing the study of brain function in health and disease.
However, few realize that its origins began in the nineteenth century with Dr. Angelo Mosso's
pioneering experiments. A foremost Italian physiologist and scientist, Angelo Mosso studied
several patients brought to him with head injuries that exposed their live brains to direct, longterm
observation. He took advantage of these rare opportunities to document, for the first time,
changes in cerebral blood flow in response to different stimuli, behaviors, and emotions, the very
same changes that are now the basis for the measurements underlying modern functional brain
imaging. Mosso was widely recognized by his contemporaries for his highly original studies,
published both in Italian in 1878 and in German in 1881. Yet there has never been a translation
through which this groundbreaking work could be appreciated by the English-speaking world.
Indeed, Angelo Mosso's sophisticated experiments were to neuroscience what surgeon William
Beaumont's in vivo observations were to gastric physiology fifty years earlier. This unique
monograph establishes Mosso's rightful role as the pioneer of brain imaging. Through it, the
modern reader, whether expert neuroscientist or interested student, can gain a new perspective on
the author's remarkable insights: how behaviors as subtle as thinking about a subject or feeling an
emotion produce the changes in pulsations of the brain that he observed and recorded for
posterity. Special features of this volume include first a brief summary of Mosso's life. Two
pioneers of modern brain imaging, Marcus E. Raichle (winner of the Kavli Prize for
Neuroscience) and Gordon M. Shepherd (Yale University Professor of Neurobiology) then review
Mosso's work and provide extensive commentary to explain its relevance to modern brain science.
The authors not only emphasize Mosso's pioneering role in brain imaging, but also his
fundamental contribution to the rise of cognitive neuroscience. The English translation (by
historian of medicine Christiane Nockels Fabbri) follows, together with all of the plates and
illustrations of the original volume. The result is a classic of neuroscience, now available for wide
appreciation by neuroscientists, neurologists, psychologists, psychiatrists, historians of science
and medicine, and the general public.

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