food-drug interaction MCQs 2

20- Absorption of drugs after oral administration is governed by the following factors in the gastrointestinal tract:
a- pH, secretions, motility.
b- secretions, length of the tract.
c- length of the tract
Answer: a
21- Enteric-coated drugs such as ___________ when administered with foods, result in _________
a- Griseofulvin (Fulvicin) and ferrous sulfate (Entron) - increased alkalinity and decreased absorption.
b- Aspirin and erythromycin - increased al¬kalinity and increased absorption.
c- Griseofulvin (Fulvicin) and ferrous sulfate (Entron) - increased acidity and increased absorption
d- Aspirin and erythromycin - increased ac¬idity and increased absorption
Answer: d
22- The excretion of an acidic drug like Phenobarbital is_______by the urine pH becoming more______.
a- decreased – acidic.
b- increased – basic.
c- decreased – basic.
d- a & b.
Answer: d
23- Laxative-cathartic drugs such as phenolphthalein and bisacodyl (Dulcolax) can cause decreased absorption
of:
a- water
b- potassium
c- sodium
d- all of the above
Answer: d
24- Many elderly persons take antacids containing aluminum and magnesium hydroxide. Large doses of aluminum
hydroxide can result in _________and magnesium hydroxide can result in _____________
a- constipation – diarrhea.
b- dehydration - gastric ulcers.
c- decreased iron absorption - macrocytic anemia.
d- none of the above.
Answer: a
25- Elderly persons frequently take aspirin for rheumatoid arthritis and, when taken chronically without meals, it can
result in_____________________
a- gastric irritation.
b- gastric bleeding.
c- iron deficiency anemia.
d- all of the above.
Answer: d