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The Joy of Sharing Science No.2, Everything you need to know about COVID-19 Biology Supplement

Etiology and the Source of COVID-19 Ada Özgirin The Structure and genetic makeup of SARS-CoV-2 Mehmet Efe Kılıç How does the epidemiology of COVID-19 differentiate from other viruses, SARS-CoV and MERS-CoV? Elif Demir, Selin Eda Sağnak How do pre-existing conditions affect COVID-19? İrem Yaşa What is the relation between gender, race and coronavirus? Ece Paksoy, Yasemin Yüksel What are different tests being implemented for COVID-19 and how do these tests compare? Eda Paksoy, Yasemin Yüksel Where are we on COVID-19 treatment? Naira Altunkeser Clinical Trials for COVID-19 Ceylin Gün

Etiology and the Source of COVID-19
Ada Özgirin
The Structure and genetic makeup of SARS-CoV-2
Mehmet Efe Kılıç
How does the epidemiology of COVID-19 differentiate from other viruses, SARS-CoV and MERS-CoV?
Elif Demir, Selin Eda Sağnak
How do pre-existing conditions affect COVID-19?
İrem Yaşa
What is the relation between gender, race and coronavirus?
Ece Paksoy, Yasemin Yüksel
What are different tests being implemented for COVID-19 and how do these tests compare?
Eda Paksoy, Yasemin Yüksel
Where are we on COVID-19 treatment?
Naira Altunkeser
Clinical Trials for COVID-19
Ceylin Gün

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Joy of Sharing Science

(Image Taken from El-Aziz & Stockand, “Recent progress and challenges in drug development

against COVID-19 coronavirus (SARS-CoV-2) - an update on the status”)

S proteins have two subunits: S1 with a ACE2 receptor binding domain/site and S2

that regulates fusion between the host cell and the viral assembly. S proteins induce

neutralization of antibodies in the host and thus induce a specific immune response

with T-cells in the host organism. Therefore, we can say that S proteins are

prominent to protective immune response in the host. Some say that vaccines that

target the S proteins of Covid-19 could be a solution but considering the future

mutations of the virus the vaccine may result in no effect ,or worse, with another

distinct immune response.

(Image Taken from El-Aziz & Stockand, “Recent progress and challenges in drug development

against COVID-19 coronavirus (SARS-CoV-2) - an update on the status”)

For developing vaccines, to have a rather lasting effect, specific enzymes and

nucleic acids that are unique to the virus have to be analyzed. Scientists have been

evaluating those for Covid-19 with real-time reverse transcription using PCR

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