microcapsules F
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3. Physico-chemical Methods
Coacervation phase separation:
• Coacervation means the separation of a liquid or phase when solution of two hydrophilic colloids are
mixed under suitable conditions.
• In this method, the three immiscible phases of core material, solvent and coating material are formed
followed by deposition of coating material on the core.
• The coating material is dissolved in a suitable solvent and the core material is uniformly dispersed in the
solution of the coating material.
• Then the coating material is phased out of its solution which starts getting deposited on the particles of
the core material.
Coat formation during coacervation-phase separation process consists of three steps carried out under
continues agitation
i. Formation of 3 immiscible phases (core material, coating material phase, liquid phase).
ii. Deposition of polymer on core material.
iii. Rigorization of coating material.