microcapsules F
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Applications of microcapsules in pharmacy
• To improve the flow properties. e.g. Thiamine, Riboflavin
• To enhance the stability. e.g. Vitamins
• To avoid incompatibilities. e.g. Aspirin and Chloramphenicol
• To convert liquids into solids. e.g. Castor oil, Eprazinone
• To reduce gastric irritation. e.g. Nitrofurantoin, Indomethacin
• To reduce the volatility of materials. e.g. Peppermint oil, Methyl salicylate
• To mask the unpleasant taste and odor. e.g. Aminophylline, castor oil
• Microencapsulation has been employed to provide protection to the core materials
against atmospheric effects, e.g., Vitamin A Palmitate.
• Separation of incompatible substance has been achieved by encapsulation
• To mask the bitter taste of drugs like Paracetamol, Nitrofurantoin etc.
• To reduce gastric and other gastro intestinal (G.I) tract irritations, For e.g., sustained
release Aspirin preparations have been reported to cause significantly less G.I. bleeding
than conventional preparations.