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EULAR 2002

Congress Preview

Lupus

Chair’s Introduction

Dear Colleagues,

Welcome to the Lupus Forum EULAR 2022 Congress Preview. This pre-congress brochure provides you with all you need to know

about the lupus content at EULAR this year, including the plenaries, posters, and Chair’s picks of the content that you shouldn’t miss.

Poster Views on Wednesday include safety data for belimumab (POS0712), baricitinib (POS0714), and rituximab (POS1320),

the hypersensitivity profile of anifrolumab (POS0708) and data on BICLA and BILAG organ domain responses in patients receiving

anifrolumab (POS0709), among others.

Thursday morning sees the What’s New In session focus on systemic lupus erythematosus, with Professor Thomas Dörner

presenting “From pathogenesis to new therapies”.

A Clinical Science Plenary on Friday spotlights joint and skin involvement in SLE, with the Lupus Forum’s Dr Victoria Werth and

myself presenting, alongside Professor Annamaria Iagnocco. Also on Friday, there are oral abstract presentations in the Recent

Novelties in SLE/Sjogren and APS session on voclosporin efficacy in achieving proteinuria treatment targets in lupus nephritis

(OP0285), and the pharmocodynamic effect of sequential belimumab and rituximab (OP0281).

It’s worth taking the opportunity to explore the Posters on Friday, with interesting submissions on voclosporin for lupus nephritis

(POS0186), Phase 3 data on efficacy and safety of baricitinib in SLE (POS0190), the effect of belimumab on SRI-4 response

(POS0183), and atacicept impact on renal function (POS0189), both in SLE.

Saturday sees a dedicated poster tour, Systemic Lupus Erythematosus: Monitoring and Management, with many posters of interest.

I’d like to draw your attention to two in particular, focusing on SLE and the improvement of mucocutaneous manifestations in

patients treated with anifrolumab (POS0367), and early improvement in physician global assessment as a predictor of long-term

retention of belimumab treatment (POS0368).

We add new content to the Lupus Forum regularly, with monthly slide summaries of key publications, podcasts discussing recent

advances, and congress materials like these. You can register for updates at lupus-forum.com or keep up to date by following us on

Twitter @LupusForum and on LinkedIn by searching “Lupus Forum”.

However you choose to attend EULAR 2022, whether in person or virtually, I hope you find our selection of highlights useful and that

you enjoy the meeting.

Kind regards,

Ed Vital

Associate Professor, University of Leeds

Key Lupus Content

Wednesday, 01 June 2022

Chairman’s Picks

All day Poster View 4

POS0705

POS0707

POS0708

POS0709

POS0712

POS0714

POS0719

Dilemma of Belimumab Therapy (Dis)Continuation During Pregnancy: Results of a Retrospective Study in EudraVigilance

Nafise Ghalandari

Potential Use of Belimumab in Lupus Patients from Argentine Cohort According Disease Activity State

Rosana Quintana

Evaluating the Hypersensitivity Profile of Anifrolumab and the Need for Preinfusion Prophylactic Treatment in Patients with SLE

Kenneth C Kalunian

Sustained BICLA and BILAG Organ Domain Responses in Patients with Systemic Lupus Erythematosus (SLE) Receiving

Anifrolumab in Two Phase 3 Trials

Ronald van Vollenhoven

Year-4 Observational Follow-Up of Belimumab Safety (Mortality and Malignancies) in Patients with SLE who Completed a

Phase 4, 52-Week, Randomised, Double-Blind Placebo-Controlled Safety Study

Saira Sheikh

Pooled Safety Analysis of Baricitinib in Patients with Systemic Lupus Erythematosus: Results from Three Randomised,

Double-Blind, Placebo-Controlled, Clinical Trials

Thomas Dörner

Rapid Efficacy of Anifrolumab in Multiple Subtypes of Recalcitrant Cutaneous Lupus Parallels Discrete Changes in

Transcriptomic and Cellular Biomarkers

Lucy Marie Carter

All day Poster View 10

POS1320

Safety And Efficacy of Rituximab in Patients with Juvenile Systemic Lupus Erythematosus: The Preliminary Data of

Retrospective Cohort Study

Rinat Raupov


Chairman’s Picks

Thursday, 02 June 2022

10:30–

11:07

What’s New In

Systemic Lupus Erythematosus

From Pathogenesis to New Therapies: What is New in SLE?

Thomas Dörner

Friday, 03 June 2022

13:30–

14:45

10:30 –

12:00

OP0281

OP0285

12:00–

13:30

POS0183

POS0186

POS0189

POS0190

Clinical Science Session

Joint and Skin Involvement in SLE

Therapeutic Algorithms to Treat Cutaneous Lupus: What is New?

Victoria Werth

The Role of Imaging in the Assessment of Joint Involvement in SLE

Annamaria Iagnocco

Joint Involvement in SLE: Clinical Assessment, Role of Biomarkers and New Therapeutic Options

Edward Vital

Oral Abstract Presentation Session

Recent Novelties in SLE/Sjogren and APS

Pharmacodynamic Effect of Sequential Belimumab (BEL) and Rituximab (RTX) Therapy in Patients (Pts) with Systemic

Lupus Erythematosus (SLE): The Phase 3, Randomised, Placebo-Controlled BLISS-BELIEVE Study

Y.K. Onno Teng

Voclosporin is Effective in Achieving Proteinuria Treatment Targets in Lupus Nephritis Defined by EULAR/ERA Recommendations

Hans-Joachim Anders

Poster View Auditorium 7

New Options in SLE-Sjogren and APS

The Effect of Belimumab on SRI-4 Response in Multiple Subgroups of Patients with Systemic Lupus Erythematosus:

Results of a Large Integrated Analysis

George Bertsias

Voclosporin for Lupus Nephritis: Results of the Two-year AURORA 2 Continuation Study

Amit Saxena

Effect of Atacicept on Renal Function in Patients with Systemic Lupus Erythematosus (SLE)

David Isenberg

Efficacy and Safety of Baricitinib in Patients with Systemic Lupus Erythematosus: Results from Two Randomised,

Double-Blind, Placebo-Controlled, Parallel-Group, Phase 3 Studies

Eric F. Morand

Saturday, 04 June 2022

10:15–

11:45

POS0367

POS0368

Poster View Auditorium 10

Systemic Lupus Erythematosus: Monitoring and Management

Improvement of Individual Mucocutaneous Manifestations in Patients with Systemic Lupus Erythematosus Treated

with Anifrolumab

Victoria Werth

Early (3 Months) Improvement in Physician Global Assessment of Disease Activity Predicts Long-Term Retention of

Belimumab Treatment in SLE: A Multicentre Observational Study of 184 Patients

George Bertsias

Developed

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