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Procs III 2011.indb - Journal of Bone & Joint Surgery, British Volume ...

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354 HELLENIC ASSOCIATION OF ORTHOPAEDIC SURGERY AND TRAUMATOLOGY<br />

090 BILATERAL SIMULTANEOUS TOTAL HIP<br />

ARTHROPLASTY: SAFETY AND EFFICACY<br />

– A META-ANALYSIS<br />

E. Tsiridis, I. Pagkalos, I. Polyzois, G. Pavlou, J.<br />

Charity, E. T i h , G. Gie, R. West<br />

Academic Department <strong>of</strong> Trauma and<br />

Orthopaedics, Leeds General Infirmary; Leeds<br />

School <strong>of</strong> Medicine, Leeds University, LS1 3EX<br />

Leeds, UK; Princess Elizabeth Orthopaedic<br />

Centre, Hip Unit, Royal Devon and Exeter<br />

Hospital, EX2 5DS Exeter, UK; Institute <strong>of</strong><br />

Health Sciences, Centre for Epidemiology and<br />

Biostatistics, Leeds University, LS1 3EX Leeds,<br />

UK; Cardio-Thoracic Anaesthetic Unit, “Blue<br />

Cross” Hospital, Thessaloniki, Greece.<br />

Comparison <strong>of</strong> the safety and effi cacy <strong>of</strong> Bilateral Simultaneous<br />

Total Hip Arthroplasty (BSTHA) with that <strong>of</strong><br />

staged (SgTHA) and unilateral (UTHA) was conducted<br />

using DerSimonian–Laird heterogeneity meta-analysis.<br />

A review <strong>of</strong> the English-language literature identifi ed<br />

23 citations eligible for inclusion. A total <strong>of</strong> 2063 bilateral<br />

simultaneous THR patients were identifi ed. Metaanalysis<br />

<strong>of</strong> homogenous data revealed that there were<br />

no statistically signifi cant differences between rates <strong>of</strong><br />

thromboembolic events (p=0.268 and p=0.365) and<br />

dislocation (p=0.877) when comparing staged or unilateral<br />

with bilateral simultaneous THR procedures. A<br />

systematic analysis <strong>of</strong> heterogenous data demonstrated<br />

that mean length <strong>of</strong> hospital stay was shorter after bilateral<br />

simultaneous THR. Blood loss was reduced after<br />

bilateral simultaneous THR in all studies except for one,<br />

and surgical time was not different between groups.<br />

This procedure was also found to be economically and<br />

functionally effi cacious when performed by experienced<br />

surgeons in specialist centres.<br />

091 CEMENT-IN-CEMENT STEM REVISION<br />

FOR VANCOUVER TYPE B PERIPROSTHETIC<br />

FEMORAL FRACTURES AFTER TOTAL HIP<br />

ARTHROPLASTY: 3 YEAR FOLLOW UP OF 24<br />

CASES<br />

T.W. Briant-Evans, D. Veeramootoo, E. Tsiridis,<br />

MJ. Hubble<br />

Princess Elizabeth Orthopaedic Centre, Royal<br />

Devon and Exeter Hospital, Barrack Road, Exeter<br />

EX2 5DW, Academic Department <strong>of</strong> Trauma and<br />

Orthopaedics, Leeds General Infirmary, Great<br />

George Street, Leeds, LS1 3EX, UK<br />

Periprosthetic fractures around a cemented femoral<br />

stem present a challenge to the treating surgeon. We<br />

propose a technique whereby a well fi xed cement mantle<br />

can be retained in cases with simple fractures that can be<br />

reduced anatomically. This technique is well established<br />

in femoral stem revision, but not in association with a<br />

fracture.<br />

24 Vancouver type B periprosthetic femoral fractures<br />

were treated by reducing the fracture and cementing a<br />

revision stem into the pre-existing cement mantle, with<br />

or without supplementary fi xation.<br />

3 patients died in the fi rst 6 months for reasons<br />

not related to surgery and one was too frail to attend<br />

follow up. The remaining 20 cases were followed up for<br />

a mean <strong>of</strong> 3.0 years. The median time to radiological<br />

and clinical union was 3.0 months (2-11). The median<br />

Modifi ed Harris Hip Score was 76.9 (35-97) and there<br />

was no sign <strong>of</strong> loosening or subsidence <strong>of</strong> the revision<br />

stems within the old cement mantle in any case at most<br />

recent follow up. One patient had further surgery for<br />

a delayed union and there were 2 subsequent fractures<br />

distal to the original fracture site in patients with poor<br />

bone stock.<br />

Our results support the use <strong>of</strong> the cement-in-cement<br />

stem revision technique in anatomically reducible periprosthetic<br />

fractures with a well preserved pre-existing<br />

cement mantle. It is particularly suitable for older<br />

patients.<br />

092 TREATMENT OF FEMORAL<br />

PERIPROSTHETIC FRACTURES AFTER TKR<br />

AND THA AT A PROVINCIAL HOSPITAL – 8<br />

YEARS EXPERIENCE<br />

K. Papageorgiou, I. Papageorgiou, P. Tilaveridid,<br />

D. Voutsas, A. Chatzioannidis, S. Gerakas<br />

Orthopaedic Department <strong>of</strong> G.H Dramas<br />

Periprosthetic fractures represent a challenging problem<br />

in joint arthroplasty the incidence <strong>of</strong> which seems to be<br />

increasing due to the big number <strong>of</strong> the arthroplasties<br />

and the increasing average life expectancy.<br />

The purpose <strong>of</strong> this study is to present the methods<br />

<strong>of</strong> treatment,the problems that we have to solve intraoperatively<br />

and our long term results about the healing<br />

procedure and the fuctional restoration.<br />

Between 2000-2008 we operated 15 femoral periprosthetic<br />

fractures(1 re-fracture). 10 <strong>of</strong> them were after<br />

hip arthroplasties.<br />

The classifi cation which used was Lewis-Rorabeck<br />

for the fractures after TKR and Vancouver for them<br />

after THA.<br />

Cause <strong>of</strong> fracture was fall and the time interval from<br />

the primary operation was 1-14years. The majority <strong>of</strong> the<br />

patients were women(14), and the mean age 65 years.<br />

13 <strong>of</strong> the 15 fractures were treated with ORIF and the<br />

remaining two need to be revised. During the follow up<br />

2 <strong>of</strong> them died due to other pathological problems.The<br />

post op follow up ranged from 1-8(3.5)years.<br />

The postoperative evaluation was done according the<br />

Harris Hip Score and the Knee Society Clinical Rating<br />

System.<br />

The fractures healed after a mean time <strong>of</strong> 6 months.<br />

Two postoperative wound infections were registered to<br />

the revised fractures and their treatment were successful<br />

with surgical debridement.<br />

All the patients are in good health condition,moving<br />

with some kind <strong>of</strong> support and they are selfreserved.<br />

As a conclusion we believe that this kind <strong>of</strong> fractures<br />

demand the proper surgical planning, prediction <strong>of</strong> all<br />

possible complications and the cooperation <strong>of</strong> other<br />

specialties and physiotherapisties.<br />

093 THE EFFECTS OF SYSTMENIC<br />

ADMINISTRATION OF SIMVASTATIN TO<br />

FRACTURE HEALING<br />

D. Chissas, P.G. Ntagiopoulos, G. Stamatopoulos,<br />

D. Verettas, K. Kazakos, A. Papalois, G. Loupasis,<br />

A. Papaeliou, G. Anastopoulos, A. Asimakopoulos<br />

2nd Department <strong>of</strong> Orthopaedic and Trauma<br />

<strong>Surgery</strong>, “G. Genimmatas” General Hospital<br />

<strong>of</strong> Athens, Athens, Greece, Department <strong>of</strong><br />

Orthopaedic and Trauma <strong>Surgery</strong>, School <strong>of</strong><br />

Medicine, Demokritus University <strong>of</strong> Thrace,<br />

Greece, Experimental-Research Department,<br />

Elpen Pharmaceuticals, Athens, Greece<br />

Several observational and experimental studies have<br />

investigated the potential anabolic effects <strong>of</strong> statins on<br />

undisturbed bone but only a few recent studies have<br />

examined the effect <strong>of</strong> statins on skeletal repair. The<br />

goal <strong>of</strong> the study is to investigate any potential early<br />

anabolic effect <strong>of</strong> the systemic administration <strong>of</strong> simvastatin<br />

in low doses (based on earlier safety and effi cacy<br />

studies on undisturbed bone) on fracture healing.<br />

Fifty-four skeletally mature male New Zealand White<br />

rabbits were used for the study. The rabbits were assigned<br />

to one <strong>of</strong> three experimental groups: a control group, and<br />

two groups that were orally administrated a diet with 10<br />

and 30 mg/kg/day <strong>of</strong> simvastatin, respectively. A complete<br />

biochemical blood count was performed to exclude<br />

drug-induced complications. Half <strong>of</strong> the animals <strong>of</strong> each<br />

group were sacrifi ced at 15 days and the other half at 30<br />

days after surgery at which time intervals healing quality<br />

was assessed. The bones were subjected to biomechanical<br />

testing, histomorphometric analysis and peripheral<br />

Quantitative Computed Tomography.<br />

In animals received simvastatin <strong>of</strong> 30 mg/kg/day<br />

a signifi cant reduction <strong>of</strong> BMD, stiffness, and energy<br />

absorbed to failure were observed. At 15 days, the<br />

amount <strong>of</strong> cartilaginous callus formation was reduced,<br />

and the void space was signifi cantly increased, in the<br />

animals <strong>of</strong> both groups that received simvastatin when<br />

compared to the control group (p

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