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C. Forero-Pineda / Research Policy 35 (2006) 808–824 817

Both economic and institutional obstacles prevent this

access. The governance structures of scientific communities,

incentive rules and confidentiality provisions in

labs increasingly limit the free flow of scientific knowledge.

The readiness and ability of the receptor of this

knowledge also strongly influences its transfer. Besides

recently tightened national security measures, secrecy

and exclusiveness surrounding scientific knowledge are

in striking contrast with economic and sociological wisdom

calling for a free flow of scientific knowledge.

Recent changes in intellectual property institutions

governing the exchange of technology affect international

scientific collaboration through the close connection

existing between scientific and R&D activities.

The extension of intellectual property into the realm

of scientific knowledge and production activities has a

direct impact on this collaboration. The new scenario

of research laboratories in the developed world has definitely

changed with regulations and incentives favouring

the appropriation of scientific knowledge. 15

Two major legal changes took place in the USA in

1980. One was the Stevenson-Wydler Technology Innovation

Act. 16 The central purpose of this Act was to

commit agencies to the full use of the results of research

and development being financed by the US Federal Government.

It also required public labs and agencies to

establish Offices of Research and Technology for this

purpose (National Academy of Sciences, 1997, p. 3).

The other was the Bayh-Dole Act. It “enables small

businesses and non profit organizations, including universities,

to retain title materials and products they invent

under federal funding”. 17 “Bayh-Dole effectively shifted

federal policy from a position of putting the result of

government-sponsored research directly into the public

domain for use by all, to a pro-patent position that

stressed the need for exclusive rights as an incentive to

industry to undertake the costly investment necessary to

bring new products to market” (National Academy of

Sciences, 1997, p. 3).

With an almost identical purpose, France approved an

Innovation and Research Law in 1999. 18 Its stated pur-

15 Bayh-Dole in the United States and the Innovation and Research

Law in France are examples of these new regulations.

16 Public Law 96-517, 6(a), 94 Stat. 3015, 3019–3027 (1980).

17 Rautiainen (2001). Subsequent to the 1980 Act, the limitations

on licensing publicly funded university inventions to large businesses

were removed, first by Presidential Executive Memorandum from the

Reagan Administration, and later (in 1984) by amendment of the

language of the Bayh-Dole Act. See Sampat (2004) in this issue of

Research Policy.

18 La loi sur l’innovation et la recherche, 12 juillet 1999.

pose is the “transfer of technology from public research

to the economy and innovative firms” (Ministère de la

Recherche, 2000).

The new academic and public research lab scenario

created in the developed countries by these legislative

initiatives has potential consequences for international

scientific collaboration that are easy to infer. The work

environment in the labs of the developed world has

changed. 19 In many university research labs that have

commercial relations with industry, special secrecy provisions

are being implemented. Interest in hosting foreign

research scholars is affected by the new environment

of secrecy, aimed at protecting the patentability of

research in progress. Sharing the latest techniques and

results with temporary, visiting scientists is more likely

to be restricted. This will be particularly the case where it

is found that the exchange visit is sponsored, directly or

indirectly by a commercial firm operating in the developing

country—although such sponsorship has historically

been a significant means of transferring scientific expertise.

Many of the most successful science policies of developing

countries are based on international scientific

exchanges where a two-way contribution to the advance

of knowledge is expected. 20 Important externalities to

local scientific communities and society are associated

with these exchanges. Mistrust and certain trade secret

provisions on the part of developed-country public or

academic laboratories directly affect the feasibility of

these policies.

Opportunities for scientific networking between scientists

in developed and developing countries are narrowed.

A climate of suspicion within the labs of developed

countries affects the presence of foreign researchers

in those teams. Both symmetric uncertainty and asymmetric

information on the eventual distribution of benefits

in case of a commercial exploitation increase

the transaction costs of reaching scientific cooperation

agreements. International scientific cooperation is particularly

affected, and small developing countries are

especially fragile, since they do not have alternative

options they can run on their own to develop frontier

scientific activities.

Comparable effects should be expected from contracts

between private corporations and public or university

labs in developing countries. These contracts

19 Owen-Smith and Powell (2001) analyse these changes. Exclusive

licensing appears to be particularly controversial in the laboratory environment

of the United States.

20 The experience of one such network, the Red Caldas, is analysed

in Forero-Pineda (1997).

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