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C. Forero-Pineda / Research Policy 35 (2006) 808–824 811

global welfare rationale for resisting global unification

of IPR regimes. But the characterization of research and

development (R&D) and diffusion processes has been

criticised as insufficiently grounded on empirical information

and, therefore, misleading in terms of the critical

policy implications that can be drawn from the models. 3

Deardorff (1992) follows the same line in questioning

a universal standard for IPR, with a simple static twocountry

model, where all inventions take place in one of

them. His main conclusion is that, for a wide set of circumstances,

it is not optimal to extend patent protection

to all countries in the world. His argument is based on

the analysis of the trade-off between higher incentives

to invention and the distortion of consumer choice by

monopoly pricing. At some point the incentives to generate

new inventions are offset by the costs of monopoly

pricing over existing technologies.

Helpman (1993) analyses the impact of tightening

intellectual property rights on terms of trade, production

composition, available products and inter-temporal

allocation of consumption. For that, he develops a tworegion

general equilibrium framework partly based on

Krugman (1979), 4 and uses alternatively exogenous and

endogenous rates of innovation. He limits the technological

activity of the less developed region to imitation.

Also, as the author explicitly recognises, the two-region

division is not adequate to deal with the heterogeneity of

less developed countries (Helpman, 1993, p. 1250), but

he claims it deals best with newly industrialised countries

interacting with developed countries. In different

ways, Helpman shows that, in the absence of foreign

investment, ‘southern’ countries tightening intellectual

property rights do not obtain benefits. Even when the

rate of innovation is responsive to IPR, its initial rise

is temporary and does not compensate for the ensuing

decline. With foreign investment by multinationals,

Helpman shows conditions for which the reallocation

of manufacturing, resulting in higher prices for larger

fractions of products, brings welfare losses to the less

developed region; and he identifies circumstances (no

foreign investment and low rate of imitation) where both

regions may benefit from relaxation of IPRs.

Lai and Qiu (2001) address the issue asking comparable

questions in a setting with both innovation and imitation.

They measure the level of protection by the length

of patents, and compare two stylised situations that are

3 For one such critique, see David (1997).

4 Krugman (1979) analysed a north-south situation where the north

led in technology development, but the issue of IPR was not addressed

directly.

assimilated to those standing before and after the Trade-

Related Intellectual Property Agreements (TRIPs). In a

two-region, stationary-state, partial-equilibrium setting

they calculate the Nash equilibrium before the agreement,

and analyse the impact of increasing the level

of protection of southern countries on north, south and

global welfare. They propose a way of relating tariff

barriers in the north with technological and industrial

development in the southern region. One result they

obtain is that the higher the protection in the north, the

lower the optimal protection in the south.

Other conclusions advanced by Lai and Qiu are not

likely to be so robust. Despite some assumptions ensuring

the asymmetry of the two regions, the model depicts

trade and technology relations between a large and a

small-developed country, rather than between one developed

and one developing country. Their results depend

critically on this structural similarity between the two

regions. One surprising and questionable conclusion

(due perhaps to the extreme partial equilibrium restrictions

they impose) is that, though the south loses when it

unilaterally increases its level of protection, global welfare

is enhanced, even when the south adopts a level of

protection higher than the north’s. Assumptions about

market size and elasticity of innovation in the south are

also critical to obtain this result. Lai and Qiu also address

north–south distributional issues of TRIPs in the context

of trade. They are discussed below.

Grossman and Lai (2002) follow the same line of discussion,

focusing on the incentives of north and south to

extend the protection of IPRs, in a non-cooperative scenario.

They assume that human capital and labour are

the factors of production of inventions. Also, the production

function for new inventions is homogenous of

degree one and the same in north and south. This would

imply that the physical marginal productivity of human

capital is larger in the developing country, where there is

less human capital. Externalities and scale economies are

excluded from the production of knowledge. Since they

do not make assumptions about structural differences

between the two innovation systems, besides a plausible

assumption of a larger human capital stock in the north,

they require an ad hoc market-size assumption to predict

longer protection of patents in the north.

Several empirical studies have addressed the same or

related issues. McCalman (2001) estimates the increase

in present value of patent protection granted to foreigners

and of patents outstanding abroad for a set of 29 developed

and developing countries. A striking result of his

calculations, based on imputed patent values, is that all

developing and some developed countries in the studied

set lose with the application of TRIPs. One of the lat-

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