POTENCIAL Q4

MEDICAL REPORT
Age: 18 years old
Starting weight: 54kg
Gender: female
Comorbidities: None
Background: patient begins treatment at Social Security for sensitive TB with 2RHZE on
01/11/2021; BK positive (++); passes to second phase on 03/12/2021 every other day with 4RH,
regular treatment until 05/14/2021; GeneXpert results obtained 03/16/2021 resistant to
Rifampicin (R).
Restart treatment on 06/04/2021 with scheme: E/Z/Amk/Lfx/Eto/Cs (4th month) until 11/30/2021
SENSITIVITY TEST:
1. Sample collection date: 03/16/2021 PCR Result date: 03/24/2021 Resistant to R.
2. Sample collection date: 06/10/2021 Genotype Result date: 07/16/2021 Resistant to
R/H.
3. Sample collection date: 06/10/2021 Genotype 2nd line Result date: 07/22/2021
Resistant to Lfx/Mfx/Km/Cm
4. Sample collection date: 06/10/2021 MGIT Result date: 07/22/2021 Resistant Amk/Cm
/ Contaminated Mfx/Lfx.
5. Sample collection date: 06/10/2021 MGIT Result date: 08/10/2021 Resistant Amk/Cm
/ Contaminated Mfx/Lfx.
6. Sample collection date: 06/10/2021 MGIT Result date: 09/10/2021 Resistant Mfx/
Sensitive Lfx 1ug/Ml
7. Sample collection date: 01/26/2022 Bacilloscopy – sputum Result date: 01/26/2022
Negative.
BACTERIOLOGICAL EVOLUTION:
I. BK 06/2021 Direct (Negative); POSITIVE culture
II. BK 07/2021 Direct (Negative); NEGATIVE Culture
III. BK 08/2021 Direct (Negative); Crop IN PROCESS
IV. BK 09/2021 Direct (Negative); Crop IN PROCESS
V. BK 10/2021 Direct (Negative); Crop IN PROCESS
VI. BK 11/2021 Direct (Negative); Crop IN PROCESS
VII. BK 01/2022 Direct (Negative)

THORAX TOMOGRAPHY REPORT WITHOUT CONTRAST 06/13/2021:
Right lung shows parenchymal consolidation with bronchial dilations and cavitation located in
segments II and III, adjacent to it tree-in-bud opacities and small nodular lesions are observed, the
rest of lung parenchyma preserved.
No pleural collections.
In this particular case, treatment failure is suspected but not confirmed according to the WHO
definition; has 1 Positive crop, then Negative; the rest pending, would the participant be eligible to
start a new treatment regimen?