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Fossilised Knowledge? - UQ eSpace - University of Queensland

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Vaccines to prevent HPV infection<br />

Zur Hausen<br />

Cancer associated Human<br />

Papillomaviruses<br />

(~1980)<br />

-Some HPVs cause cancer<br />

- Virus can’t be grown in the lab<br />

1:J. Zhou, X. Y. Sun, D. J. Stenzel, and I. H. Frazer. Virology 185 (1):251-257, 1991.<br />

Virus Like particles1 Jian Zhou<br />

(~1990)<br />

- L1 recombinant DNA<br />

- Self assembly to VLPs<br />

- VLPs highly immunogenic

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