Fossilised Knowledge? - UQ eSpace - University of Queensland

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HPV vaccines– frequently asked questions • Do the vaccines work? • Are the vaccines safe? • How long should protection last? • Who should be vaccinated? • What do we need to know next?
HPV vaccine Phase III trial outcomes Study 1 Vaccine 2 No <strong>of</strong> subjects End-points Vaccine efficacy Vaccine Control % (confidence limits) Koutsky 6/11/16/18 6087 6080 CIN 2/3 AIS 98 (86-100) Ault 6/11/16/18 10291 10292 CIN 2/3 AIS 99 (93-100) Garland 6/11/16/18 Joura 6/11/16/18 2241 2261 2258 2279 Parvonen* 16/18 9319 9325 CIN 2/3 AIS GW VIN VAIN 7811 7785 VIN2/3 VAIN 2/3 100 (94-100) 100 (94-100) 100 (72-100) CIN2,3 93 (89-98) Adapted from J. A. Kahn and R. D. Burk. Papillomavirus vaccines in perspective. Lancet 369 (9580):2135-2137, 2007. *: Phase III bivalent vaccine data from 25 th IPV Malmo 2009
Page 1 and 2: Fossilised knowledge? Libraries as
Page 3 and 4: The great library at Ephesus
Page 5 and 6: The Bodleian Library Oxford: Interi
Page 10 and 11: The University of Queensland from t
Page 12: The New Translational Research Inst
Page 15 and 16: Research Challenges • Too Much Kn
Page 17 and 18: Wiki or what? From Wikipedia, the f
Page 19 and 20: PAPER I DON’T THINK YOU CAN ACCUS
Page 21: Life expectancy is increasing…
Page 24 and 25: AGRARIAN (botanicals) • Hyponutri
Page 26 and 27: A short aside on the history of med
Page 28 and 29: Cancer control in the 21 st century
Page 30 and 31: Behavior modification for • Smoki
Page 32 and 33: Some Genetics Terminology and Facts
Page 34 and 35: Next-Generation Sequencing • 1980
Page 36 and 37: Published Genome-Wide Associations
Page 38 and 39: WEHI 1982 Canberra 2008
Page 40 and 41: Viruses Other Infection causes >20
Page 42 and 43: Vaccines to prevent HPV infection Z
Page 46 and 47: Protection against CIN2/3 -all HPV
Page 48 and 49: Delivering HPV vaccines in the deve
Page 50 and 51: Education : parents, children, staf
Page 52 and 53: Basic Research Research as the driv

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