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New Developments in QuEChERS methodology

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pH-Labile Compounds<br />

EPRW 2006, Corfu<br />

Slide 9<br />

Some Pesticides are sensitive to pH<br />

and degrade at high or low pH-values<br />

• In the sample (dur<strong>in</strong>g process<strong>in</strong>g and storage)<br />

� Keep low temperatures<br />

• Dur<strong>in</strong>g sample preparation<br />

� Work fast, adjust pH<br />

• In the extract dur<strong>in</strong>g storage (1 week is common)<br />

� Keep low temperatures, adjust pH,<br />

after dispersive SPE with PSA, pH may reach values exceed<strong>in</strong>g 8

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