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ANNUAL REPORT 2010 - Loughborough University

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18<br />

IMCRC Current<br />

RESEARCh ThEMES<br />

Customised Products<br />

This theme seeks to make products that<br />

suit the requirements of customers at a cost<br />

similar to mass-produced goods. Designers,<br />

manufacturers, users, distributors and<br />

world-class academics are together<br />

generating novel design and manufacturing<br />

techniques. The following projects are<br />

included within this theme.<br />

Project 185 - Tailored Injury Prevention and<br />

Performance Improvement for Protective<br />

Sports garments (SCUTA) aims to produce<br />

comfortable, conformable, personal,<br />

protective equipment for athletes taking<br />

part in three different sports. New models<br />

of assessment of impact injuries to the body<br />

are being evaluated and novel material<br />

structures being designed to help dissipate<br />

the impact of the forces incurred within<br />

these sports.<br />

Project 219 – A Unique human grip<br />

Simulator for Robotic Testing of Sports<br />

Equipment, is developing a mechanism<br />

of the human grip to more realistically<br />

simulate the motions of the hand when<br />

gripping and manipulating lightweight,<br />

flexible structures. The project is focusing<br />

on golf, with the ultimate objective to<br />

develop a golf robot capable of recreating<br />

the unique swing profiles of different<br />

golfers.<br />

The IMCRC is renowned for its expertise<br />

in modelling for injury prevention and<br />

engineering design. Project 281 - Rail<br />

Transport Safety for Pregnant occupants<br />

- Preliminary Investigations, aims to have<br />

an impact on safety considerations in<br />

railway transport for pregnant women and<br />

contribute to UK public transport design,<br />

without compromising the safety of nonpregnant<br />

occupants.<br />

Project 254 - Feasibility Study for<br />

Anthropometric Test Device and<br />

Computational Models for Ageing occupants<br />

has been focussed on producing guidelines<br />

for automotive safety engineers and medical<br />

engineers, for the representation of ageing<br />

vehicle occupants in order to minimise the<br />

risk of injuries and fatality as a result of<br />

road traffic accidents.<br />

AnnuAl RepoRt <strong>2010</strong><br />

healthy & Secure Future<br />

This IMCRC theme is providing enhanced<br />

environments and products to improve our<br />

safety and security, and promote healthier<br />

lifestyles. Research within this theme<br />

includes facilitating healthcare delivery<br />

through the Centre’s involvement in the<br />

cross institutional ‘HaCIRIC’ project and<br />

the transformation of bioscience onto<br />

commercial practice through the ‘Remedi’<br />

Grand Challenge.<br />

Project 248 - The health and Care<br />

Infrastructure Research and Innovation<br />

Centre (haCIRIC) is focussed on<br />

researching the infrastructure needed to<br />

deliver healthcare. This is a collaboration<br />

project with research centres at Imperial<br />

College, <strong>Loughborough</strong>, Reading, and<br />

Salford. <strong>Loughborough</strong>-led aspects of the<br />

research include: the development of a<br />

continuous improvement framework for<br />

the procurement of primary healthcare<br />

facilities; the adoption of disruptive<br />

innovation as a mechanism for change in<br />

the NHS; metrics, models and toolkits for<br />

a sustainable urban environment; proactive<br />

resilient engineering and emergency<br />

mitigation protocols; the innovative<br />

design of well performing built healing<br />

environments; and the design of sustainable<br />

healthcare infrastructure and healthcare<br />

facilities. HaCIRIC now has regular input<br />

into Department of Health and NHS policy<br />

process in healthcare technology and<br />

innovation management.<br />

The grand Challenge project 214 –<br />

Regenerative Medicine: A New Industry<br />

(Remedi) is led by Prof. David Williams<br />

at the <strong>Loughborough</strong> IMCRC. This Grand<br />

Challenge includes two IMRCs, three other<br />

universities and eleven key collaborators,<br />

in a £7 million project over five years.<br />

It aims to demonstrate how established<br />

bioscience can be transformed into profitable<br />

commercial practice and generate affordable<br />

therapies, while developing the science<br />

of manufacture. The <strong>Loughborough</strong>-led<br />

research is focussed on creating process<br />

demonstrators for three products: scaffolds,<br />

cells and tissues, and on SME tools. The<br />

project has already demonstrated the<br />

automated, scaleable culture of: human<br />

bone marrow and umbilical cord blood<br />

derived hMSCs; multiple hESC lines in<br />

serum‐free or feeder‐free conditions; two<br />

‘near to clinic’ commercial cell types, verified<br />

against commercially relevant endpoints;<br />

differentiated otic progenitor cells from<br />

hESCs for application to hearing disorder<br />

therapy; and human endothelial progenitor<br />

cells for drug screening applications.<br />

Project 223 - Complex Bone Surgery<br />

Simulation is engineering tailored bone<br />

phantoms with realistic visual and physical<br />

properties, to simulate surgical practices<br />

and enhance medical training. This research<br />

is already influencing surgical teaching.<br />

Is the quality of life of elderly people<br />

affected by biomechanical changes in the<br />

body? Project 298 - Investigations to Prevent<br />

Falls in the Ageing Population, is a unique<br />

study into the role spine curvature plays in<br />

postural stability and falls in old age.<br />

Project 220 - Understanding the older<br />

Construction Worker, is identifying changes<br />

required in the construction workplace,<br />

and in the tools and equipment used, if<br />

older workers are to remain productive in<br />

the industry. This research is important<br />

for health and safety considerations as the<br />

average age of the construction worker<br />

continues to increase.<br />

The Project 263 - The Relative Value and<br />

Systemic Implications of Counter-Terrorism<br />

Measures, is protecting key components<br />

of the built environment by evaluating the<br />

systemic implications associated with the<br />

use of counter-terrorism measures. The<br />

project is contributing to future legislation,<br />

guidelines and codes of practice.<br />

Project 300 - Link with the <strong>University</strong><br />

of Milan in Commercial Exploitation of<br />

Bioscience was established in order to<br />

form a link with the <strong>University</strong> of Milan<br />

in the area of commercial exploitation<br />

of bioscience. By enabling researchers<br />

to access capabilities and work in<br />

development for activity in micro and<br />

nano-biotechnology at <strong>Loughborough</strong>, and<br />

bio-related processing and microfluidics<br />

capabilities in Milan, an early feasibility<br />

trial for high adhesion electro-less plating<br />

of thermoplastic polymers using a nanocomposite<br />

base layer has been undertaken.<br />

Project 303 - Modelling Complex Sustainable<br />

Urban Environments for 2050, is exploring<br />

the use of systems dynamics for modelling<br />

the effective delivery of infrastructure and<br />

services, together with potential applications<br />

of complexity theories in strategic decisionmaking<br />

for the healthcare industry.<br />

Project 308 - The use of innovative equipment<br />

and techniques to improve construction<br />

safety on the Birmingham New Street Station<br />

Refurbishment project, will investigate<br />

innovative multimedia methods used in the<br />

safety induction process on a major building<br />

refurbishment contract in order to produce<br />

guidelines for effective design induction<br />

processes for construction workers.

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