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Current treatment for severe back pain from disc degeneration Major Causes of Lumbar Disc Degeneration Overweight & Obesity ? Age Lumbar Disc Degeneration Genetics Biomechanics 4
Hong Kong Degenerative Disc Disease Cohort Study • Population-based study (since 2001) • Currently 3,500 Southern Chinese subjects • Largest cohort in the world assessed with MRI Assessment of Disc Degeneration (DDD Score) Grade Description 0(Normal) No signal changes Radiographic Criteria for Disc Degeneration 5 lumbar discs scored for disc degeneration and “summated” for DDD Score (potential score range: 0 to 15) 1 Slight decrease in signal intensity of the nucleus pulposus 2 Hypointense nucleus pulposus with normal disc height 3 Hypointense nucleus pulposus with disc space narrowing Schneiderman G et al. Spine 1987;12:276-81 End-Stage 5
Page 1 and 2: HKU finds overweight and obesity si
Page 3: ✖ Low Back Pain ‐ Rehabilitatio
Page 7 and 8: Low Back Pain Odds Ratio (95% CI) 6
Page 9 and 10: HKU research findings Prevalence of
Page 11 and 12: Mean DDD Score (Lumbar Spine) 4 3 2
Page 13 and 14: Obesity 72% increased risk for “e
Page 15 and 16: Adult Overweight and Obesity in Hon
Page 17 and 18: Major Causes of Lumbar Disc Degener

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