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Curriculum Vitae - University of Cambridge

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1 Personal details<br />

<strong>Curriculum</strong> <strong>Vitae</strong><br />

Gabi Kaminski<br />

Name: Gabriele Susanne Kaminski (née Schierle)<br />

2 Employment / Education<br />

2005 - present Senior scientist at the department <strong>of</strong> Chemical Engineering,<br />

Univeristy <strong>of</strong> <strong>Cambridge</strong>, UK<br />

Maternity leave in between.<br />

2004 - 2005 Scientific Consultant for Zyentia Ltd., <strong>Cambridge</strong>, UK<br />

2001 - 2005 Post-doctoral scientist at the Centre for Brain Repair, <strong>University</strong> <strong>of</strong><br />

<strong>Cambridge</strong>, UK<br />

Maternity leave in between.<br />

2000 - 2002 Scientific consultant and project leader for a leading Danish<br />

pharmaceutical company (Lundbeck A/S)<br />

1999 – 2001 Post-doctoral scientist at the department <strong>of</strong> Physiological Sciences,<br />

Lund <strong>University</strong>, Sweden<br />

1999 Ph.D. in Medicine at the department <strong>of</strong> Physiological Sciences, Lund<br />

<strong>University</strong>, Sweden<br />

1996 Swiss diploma in Biology at the Université de Fribourg, Switzerland<br />

(magna cum laude)<br />

1990 Final exam taken at the Bundesoberstufenrealgymnasium in Feldkirch,<br />

Austria (with distinction)<br />

3 Prizes / Awards<br />

(a) Foulkes Foundation Fellowship (2005)<br />

(b) Wellcome Trust Advanced Training Fellowship (2002)<br />

(c) Future Scientific Leader award from the Swedish Society <strong>of</strong> Medical Research (2000)<br />

(d) Promising Young Scientist award from the Parkinson’s Disease Foundation (USA)<br />

(1999)<br />

(e) Marie Curie fellowship <strong>of</strong> the EU (1996)


4 Publications<br />

G.S. Schierle, J.-C. Gander, C.D.’Orlando, M.R. Celio, D.M. Vogt Weisenhorn (1997) Calretinin-immunoreactivity<br />

during postnatal development <strong>of</strong> the rat isocortex: a qualitative and quantitative study. Cerebral Cortex 7:130-142.<br />

G.S. Schierle, J. Karlsson, and P. Brundin (1998) MK-801 treatment does not enhance the survival <strong>of</strong> grafted<br />

dopamine neurones. Neuroreport 9:1113-1116.<br />

G.S. Schierle, O. Hansson, M. Leist, P. Nicotera, H. Widner, and P. Brundin (1999) Caspase inhibition reduces<br />

apoptosis and increases survival <strong>of</strong> nigral transplants. Nature Medicine 5:97-100.<br />

G.S. Schierle, M. Leist, J.C. Martinou, H. Widner, P. Nicotera, P. Brundin (1999). Differential effects <strong>of</strong> Bcl-2<br />

overexpression on fiber outgrowth and survival <strong>of</strong> embryonic dopaminergic neurons in intracerebral transplants.<br />

European Journal <strong>of</strong> Neuroscience 11:3073-3081.<br />

G.S. Kaminski Schierle, O. Hansson, and P. Brundin (1999). Flunarizine improves the survival <strong>of</strong> grafted<br />

dopaminergic neurons. Neuroscience 94:17-20.<br />

G.S. Kaminski Schierle, O. Hansson, P. Nicotera, P. Brundin, M. Leist (1999). Neuronal death in nigral grafts in the<br />

absence <strong>of</strong> poly (ADP-ribose) polymerase activation. Neuroreport 10:3347-3351.<br />

G.S. Schierle, P. Brundin (1999) Excitotoxicity plays a role in the death <strong>of</strong> tyrosine hydroxylase-immunopositive nigral<br />

neurons cultured in serum-free medium. Experimental Neurology 157:338-348.<br />

P. Brundin, G.S. Kaminski Schierle. Neuroprotective strategies in neural grafting (1999). In: Dunnett SB, Boulton AA,<br />

Baker GB (editors). Neural Transplantation Methods. Totowa, NJ: Humana Press Inc, pp. 411-440.<br />

P. Brundin, J. Karlsson, M. Emgård, G.S. Kaminski Schierle, O. Hansson, Å. Petersén, R.F. Castilho (2000)<br />

Improving the survival <strong>of</strong> grafted dopaminergic neurons: a review over current approaches. Cell Transplantation<br />

9:179-195. Cited by 185.<br />

O. Hansson, R.F. Castilho, G.S. Kaminski Schierle, J. Karlsson, P. Nicotera, M. Leist, P. Brundin (2000) Additive<br />

effects <strong>of</strong> caspase inhibitor and lazaroid on the survival <strong>of</strong> transplanted rat and human embryonic dopamine neurons.<br />

Experimental Neurology 164: 102-111.<br />

U. Mundt-Petersen, J. Karlsson, G.S. Kaminski Schierle, and P. Brundin (2000) The effects <strong>of</strong> MK-801 or U-83836E<br />

on the survival <strong>of</strong> grafted embryonic striatal neurones. Cell Transplantation 9:73-78.<br />

E.N. Maciel, G.S. Kaminski Schierle, O. Hansson, P. Brundin, R.F. Castilho (2003). Cyclosporin A and Bcl-2 do not<br />

inhibit quinolinic acid-induced striatal excitotoxicity in rodents. Experimental Neurology 183:430-7.<br />

J. Bisgaard Boll, M.A. Geist, G.S. Kaminski Schierle, K. Petersen, M. Leist, E. Vaudano (2004). CEP-1347 improves<br />

the survival <strong>of</strong> embryonic dopaminergic neurons in culture and after grafting into the striatum <strong>of</strong> hemiparkinsonian<br />

rats. Journal <strong>of</strong> Neurochemistry 88: 698-707.<br />

Y.H. Ahn, J.C. Bensadoun, P. Aebischer, A.D. Zurn, A. Seiger, A. Bjorklund, O. Lindvall, L. Wahlberg, P. Brundin, G.<br />

S. Kaminski Schierle (2005). Increased fiber outgrowth from xeno-transplanted human embryonic dopaminergic<br />

neurons with co-implants <strong>of</strong> polymer-encapsulated genetically modified cells releasing glial cell line-derived<br />

neurotrophic factor. Brain Research Bulletin 66:135-42.<br />

S. Schlachter, A. D. Elder, A. Esposito, G. S. Kaminski, J. H. Frank, L. K. van Geest, and C. F. Kaminski (2009).<br />

mhFLIM: Resolution <strong>of</strong> heterogeneous fluorescence decays in widefield lifetime microscopy. Opt. Express 17: 1557-<br />

1570.<br />

S. Schlachter, S. Schwedler, A. Esposito, G.S. Kaminski Schierle, G.D. Moggridge, C.F. Kaminski (2009). A method<br />

to unmix multiple fluorophores in microscopy images with minimal a priori information. Opt. Express 17: 22747-60.<br />

A. Esposito, S. Schlachter, G.S. Schierle, A.D. Elder, A. Diaspro, F.S. Wouters, C.F. Kaminski, A.I. Iliev. Quantitative<br />

fluorescence microscopy techniques (2009). Methods Mol Biol.586:117-42.<br />

A.D. Elder, A. Domin, G.S. Kaminski Schierle, C. Lindon, J. Pines, A. Esposito, and C.F. Kaminski. A quantitative<br />

protocol for dynamic measurements <strong>of</strong> protein interactions by FRET-sensitized fluorescence emission (2009). Journal<br />

<strong>of</strong> the Royal Society Interface 6: 59-81.<br />

T.J. van Ham, A. Esposito, J.R. Kumita, S.T. Hsu, G.S. Kaminski Schierle, C.F. Kaminski, C.M. Dobson, E.A.A.<br />

Nollen, C.W. Bertoncini. Towards multiparametric fluorescent imaging <strong>of</strong> amyloid formation: Studies <strong>of</strong> a YFP model<br />

<strong>of</strong> alpha-synuclein aggregation (2010). J. Mol. Biol. 395: 627–642.


S. Chakrabortee, F. Meersman, G.S. Kaminski Schierle, C.W. Bertoncini, B. McGee, C.F. Kaminski, A. Tunnacliffe.<br />

Catalytic and chaperone-like functions in an intrinsically disordered protein associated with desiccation tolerance<br />

(2010). PNAS 107:16084-16089.<br />

E.K. Esbjorner, C. Bertoncini, S. Schlachter, C.M. Dobson, C. Kaminski, G.S. Kaminski Schierle. Multiparametric<br />

fluorescence microscopy imaging <strong>of</strong> amyloid beta allows for direct observations <strong>of</strong> protein misfolding in vitro and in<br />

cells (2010). FEBS JOURNAL 277: 86-86.<br />

A. Esposito, A.N. Bader, S. Schlachter, D.J. van den Heuvel, G.S. Kaminski Schierle, A.R. Ventikaraman, C.F.<br />

Kaminski, H.C. Gerritsen. Hyper dimensional imaging microscopy by confocal laser scanning spectropolarimetry<br />

(2011) Optics Express, 19:2546–2555.<br />

F.T.S. Chan, C.F. Kaminski, G.S. Kaminski Schierle. HomoFRET fluorescence anisotropy imaging as a tool to study<br />

molecular self assembly in live cells.(2011). ChemPhysChem, DOI:10.1002/cphc.201000833, in press.<br />

G.S. Kaminski Schierle, C.W. Bertoncini, F.T.S. Chan, A.T. van der Goot, S. Schwedler, J. Skepper, S. Schlachter, T.<br />

van Ham, A. Esposito, J. Kumita, E.A.A. Nollen, C.M. Dobson, C.F. Kaminski. Optical imaging <strong>of</strong> the nature <strong>of</strong> αsynuclein<br />

amyloid formation in vitro and in vivo (2011). ChemPhysChem, DOI:10.1002/cphc.201000996, in press<br />

G. S. Kaminski Schierle, S. van de Linde, M. Erdelyi, E. K. Esbjörner, T. Klein, E. Rees, C. W. Bertoncini, C. M.<br />

Dobson . M. Sauer, C. F. Kaminski . In Situ Measurements <strong>of</strong> the Formation and Morphology <strong>of</strong> Intracellular ß-Amyloid<br />

Fibrils by Super-Resolution Fluorescence Imaging-submitted to JACS.

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