24 Forensic Human Identification matching samples from the scene of crime to suspects and paternity testing is well established and is unlikely to change fundamentally over the next ten to twenty years. Rather, the equipment and methodology along with the interpretation of the data will be refined. Portable testing facilities may play a limited role in the foreseeable future. The use of DNA databases will also increase. Many countries are following the British model (although many are governed by legislation that provides its citizens with more rights) and some smaller countries are planning to profile the entire resident population; an idea mooted by senior police officers in the U.K. More types of analysis will also become more commonplace, for example, using single nucleotide polymorphisms to infer the geographical origins of either scene of crime material or human remains. The analysis of compromised samples is also likely to develop further; the World Trade Center identifications acted as a primer for the development of SNPs for typing highly degraded remains that could not be analyzed using conventional methodologies. Further Reading Buckleton, J., Triggs, C.M., and Walsh, S.J., Eds., Forensic DNA Evidence Interpretation, CRC Press, Boca Raton, FL, 2005. Butler, J., Forensic DNA Typing: Biology and Technology behind STR Markers, Academic Press, London, 2001. Butler, J., Forensic DNA Typing: Biology and Technology behind STR Markers, 2nd ed., Elsevier Academic Press, London, 2005. Evett, I.W. and Weir, B.S., Interpreting DNA Evidence, Sinauer Associates, Inc., Sunderland, MA, 1998. Inman, K. and Rudin, N., <strong>An</strong> introduction to Forensic DNA analysis, 2nd ed., CRC Press, Boca Raton, FL, 2001. Klug, W.S. and Cummings, M.R., Concepts of Genetics (International Edition), Prentice Hall International, Upper Saddle River, NJ, 2005. Kobilinsky, L., Liotti, T.F., and Oeser-Sweat, J., DNA Forensic and Legal Applications, John Wiley & Sons, Hoboken, NJ, 2005. Lincoln, P.J. and Thomson, J., Eds., Forensic DNA Profiling Protocols, Humana Press Inc., Totowa, NJ, 1998. National Research Council, The Evaluation of Forensic DNA Evidence, National Academy Press, Washington, DC, 1996. References <strong>An</strong>derson, S., Bankier, A.T., Barrell, B.G., Debruijn, M.H.L., Coulson, A.R., Drouin, J., Eperon, I.C., Nierlich, D.P., Roe, B.A., Sanger, F., Schreier, P.H., Smith, A.J.H., Staden, R., and Young, I.G., Sequence and organization of the human mitochondrial genome, Nature 290, 457–465, 1981. <strong>An</strong>drews, R.M., Kubacka, I., Chinnery, P.F., Lightowlers, R.N., Turnbull, D.M., and Howell, N., Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA, Nat Genet 23, 147–147, 1999. <strong>An</strong>kelSimons, F. and Cummins, J.M., Misconceptions about mitochondria and mammalian fertilization: Implications for theories on human evolution, Proc Natl Acad Sci USA 93, 13859–13863, 1996. © 2007 by Taylor & Francis Group, LLC
DNA 25 <strong>An</strong>slinger, K., Selbertinger, U., Bayer, B., Rolf, B., and Eisenmenger, W., Ninhydrin treatment as a screening method for the suitability of swabs taken from contact stains for DNA analysis, Int J Legal Med 118, 122–124, 2004. Ballantyne, J., Serology, in Siegel, J.A., Saukko, P.J., and Knupfer, G.C., Eds., Encyclopedia of Forensic Sciences. Academic Press, San Diego, 2000, pp. 1322–1331. Brown, W.M., George, M., and Wilson, A.C., Rapid evolution of animal mitochondrial-DNA, Proc Natl Acad Sci USA 76, 1967–1971, 1979. Budowle, B., Moretti, T.R., Baumstark, A.L., Defenbaugh, D.A., and Keys, K.M., Population data on the thirteen CODIS core short tandem repeat loci in African Americans, U.S. Caucasians, Hispanics, Bahamians, Jamaicans, and Trinidadians, J Forensic Sci 44, 1277–1286, 1999. Carracedo, A., Bar, W., Lincoln, P., Mayr, W., Morling, N., Olaisen, B., Schneider, P., Budowle, B., Brinkmann, B., Gill, P., Holland, M., Tully, G., and Wilson, M., DNA commission of the international society for forensic genetics: guidelines for mitochondrial DNA typing, Forensic Sci Int 110, 79–85, 2000. Corach, D., Risso, L.F., Marino, M., Penacino, G., and Sala, A., Routine Y-STR typing in forensic casework, Forensic Sci Int 118, 131–135, 2001. Cotton, E.A., Allsop, R.F., Guest, J.L., Frazier, R.R.E., Koumi, P., Callow, I.P., Seager, A., and Sparkes, R.L., Validation of the AMPFlSTR (R) SGM Plus (TM) system for use in forensic casework, Forensic Sci Int 112, 151–161, 2000. Edwards, A., Civitello, A., Hammond, H.A., Caskey, C.T., DNA typing and genetic-mapping with trimeric and tetrameric tandem repeats, Am J Hum Genet 49, 746–756, 1991. Excoffier, L. and Yang, Z.H., Substitution rate variation among sites in mitochondrial hypervariable region I of humans and chimpanzees, Mol Biol Evol 16, 1357–1368, 1999. Foster, E.A., Jobling, M.A., Taylor, P.G., Donnelly, P., de Knijff, P., Mieremet, R., Zerjal, T., and Tyler-Smith, C., Jefferson fathered slave’s last child, Nature 396, 27–28, 1998. Frudakis, T., Venkateswarlu, K., Thomas, M.J., Gaskin, Z., Ginjupalli, S., Gunturi, S., Ponnuswamy, V., Natarajan, S., and Nachimuthu, P.K., A classifier for the SNP-based inference of ancestry, J Forensic Sci 48, 771–782, 2003. Gill, P., Application of low copy number DNA profiling, Croatian Med J 42, 229–232, 2001a. Gill, P., <strong>An</strong> assessment of the utility of single nucleotide polymorphisms (SNPs) for forensic purposes, Int J Legal Med 114, 204–210, 2001b. Gill, P., Foreman, L., Buckleton, J.S., Triggs, C.M., and Allen, H., A comparison of adjustment methods to test the robustness of an STR DNA database comprised of 24 European populations, Forensic Sci Int 131, 184–196, 2003. Gill, P., Ivanov, P.L., Kimpton, C., Piercy, R., Benson, N., Tully, G., Evett, I., Hagelberg, E., and Sullivan, K., Identification of the remains of the Romanov family by DNA analysis, Nat Genet 6, 130–135, 1994. Gill, P., Jeffreys, A.J., and Werrett, D.J., Forensic application of DNA fingerprints, Nature 318, 577–579, 1985. Gill, P., Werrett, D.J., Budowle, B., and Guerrieri, R., <strong>An</strong> assessment of whether SNPs will replace STRs in national DNA databases, Sci Justice 44, 51–53, 2004. Goodwin, W., Linacre, A., and Vanezis, P., The use of mitochondrial DNA and short tandem repeat typing in the identification of air crash victims, Electrophoresis 20, 1707–1711, 1999. Greenspoon, S.A., Scarpetta, M.A., Drayton, M.L., and Turek, S.A., QIAamp spin columns as a method of DNA isolation for forensic casework, J Forensic Sci 43, 1024–1030, 1998. © 2007 by Taylor & Francis Group, LLC
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