Table of Contents - PAO Annual Meeting 2012
Table of Contents - PAO Annual Meeting 2012
Table of Contents - PAO Annual Meeting 2012
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
Free Paper Program<br />
Poster Presentation Program<br />
Oral Free Papers<br />
Poster Presentations<br />
<strong>Table</strong> <strong>of</strong> <strong>Contents</strong><br />
1 - 4<br />
4 - 8<br />
9 - 27<br />
28 - 48<br />
from BA to CLINIC
<strong>PAO</strong> Free Paper Program<br />
DAY 3 • SUNDAY, DECEMBER 2, <strong>2012</strong><br />
Function Room 1<br />
SVC – 2<br />
CATARACT BREAKFAST SURGICAL VIDEO CONFERENCE<br />
9:00 – 9:07 am<br />
Lensectomy with Scleral Suturing <strong>of</strong> Cionni Ring with<br />
In-thebag Lens Implantation for Ectopia Lentis Secondary to<br />
Marfan Syndrome<br />
Reginald Robert Tan, Jay Marianito S. Vicencio<br />
DAY 1 • FRIDAY, NOVEMBER 30, <strong>2012</strong><br />
Function Room 2<br />
9:05 am – 11:30 am<br />
SY – 2<br />
NEURO-OPHTHALMOLOGY SYMPOSIUM<br />
Chair: Lourdes T. Ang, MD<br />
Co-chair: Rolan Mangahas, MD<br />
10:51am – 11:05 am<br />
FP-1<br />
Efficacy <strong>of</strong> Vitamin B in Preventing Color Vision Abnormalities<br />
Among Patients Undergoing DOTS for Tuberculosis<br />
Jan Michael R. Reyes, Ma. Melizza Theresa T. Ramirez, Anne<br />
Marfe L. Tan, Roland B. Bagnes, II, Evelyn S. Morabe, Emerson<br />
M. Cruz, Ma. Lourdes R. Nañagas<br />
Jose R. Reyes Memorial Medical Center, Philippines<br />
11:06 am – 11:14 am<br />
FP-2<br />
A Comparison <strong>of</strong> Visual Outcomes in Optic Neuritis Patients<br />
Treated with Intravenous Dexamethasone and<br />
Methylprednisolone at a Tertiary Hospital : A Retrospective Study<br />
Shalam Siao, Lee Allen D. Cloma, Leonides Karlo C. Melendres, III<br />
DOH Eye Center East Avenue Medical Center, Philippines<br />
DAY 2 • SATURDAY, DECEMBER 1, <strong>2012</strong><br />
Function Room 1<br />
SY – 10<br />
PUBLIC HEALTH OPHTHALMOLOGY SYMPOSIUM<br />
4:40 pm – 4:47 pm<br />
FP-3<br />
Barriers to the Utilization <strong>of</strong> Eye Care Services in a Rural Setting<br />
Mateo Andro R. Geronimo, Ma. Victoria A. Rondaris<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
1<br />
4:47 pm – 4:54 pm<br />
FP-4<br />
Psychometric Analysis <strong>of</strong> the 25-Item National Eye Institute<br />
Visual Function Questionnaire (NEI VFQ-25) Filipino Version<br />
Lawrence Joseph S. Valdez , Ma. Victoria A. Rondaris<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
4:54 pm – 5:01 pm<br />
FP-5<br />
Efficacy <strong>of</strong> Dry Heat Utilizing a Commercial Oven Toaster in<br />
the Sterilization <strong>of</strong> Stainless Steel Discs<br />
Maria Cielo R. Dizon, Robert Christian F. Reyes<br />
FREE PAPER SESSION 1<br />
<strong>Meeting</strong> Rooms 4-6<br />
8:30 - 10:30 am<br />
Chair: Jennifer Bernabe-Ko, MD<br />
Co-Chair: Marichele Aventura-Isidro, MD<br />
External Disease and Cornea<br />
8:30 am - 8:37 am<br />
FP-6<br />
Dry Eye After Clear Cornea Phacoemulsification<br />
Peter Mark G. Chao, Ruben Lim Bon Siong<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines<br />
8:38 am - 8:45 am<br />
FP-7<br />
Petroleum Jelly Versus Tea Tree Oil and Tea Tree Facial<br />
Wash Lid Scrub in Patients with Blepharitis Associated with<br />
Above-normal Demodex Count<br />
Karen Angela L. Tiuseco, Johann Michael G. Reyes<br />
Ruben Lim Bon Siong, Eleonore B. Iguban<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines<br />
8:46 am - 8:53 am<br />
FP-8<br />
Antifungal Activity <strong>of</strong> Voriconazole Against Local Isolates:<br />
An In Vitro Study<br />
Karina Q. De Sagun-Bella, Noel S. Cariño, Archimedes D. Agahan,<br />
Leo DP. Cubillan<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines<br />
8:54 am - 9:01 am<br />
FP-9<br />
No Glue, No Suture Technique? Of Pterygium Surgery: A<br />
Local Experience<br />
Ma. Melizza Theresa T. Ramirez¹, Emerson M. Cruz², Evelyn S.<br />
Morabe¹, Roland B. Bagnes, II¹, Jan Michael R. Reyes¹<br />
¹Jose R. Reyes Memorial Medical Center, Philippines, ²Asian Eye<br />
Institute, Philippines
9:11 am - 9:18 am<br />
FP-10<br />
A Randomized Controlled Trial <strong>of</strong> Tobramycin-<br />
Dexamethasone, Tobramycin, and Nepafenac Eye Drops in<br />
Patients with Acute Follicular Conjunctivitis<br />
Melquiades D. Figueroa<br />
Jose R. Reyes Memorial Medical Center, Philippines<br />
9:19 am - 9:26 am<br />
FP-11<br />
Retrospective Study Comparing Femtosecond Lenticule<br />
Extraction (FLEX) with Femtosecond Laser In-Situ Keratomileusis<br />
For Myopia<br />
Tina Marie Saban-Roa, Irwin Y. Cua, Ruben Lim Bon Siong<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
9:27 am - 9:34 am<br />
FP-12<br />
In Vitro Efficacy <strong>of</strong> Imipenem Compared to Vancomycin<br />
against S. aureus in Intravitreal Concentration<br />
Ian Ethelbert Dy<br />
University <strong>of</strong> Sto. Tomas Hospital, Philippines<br />
9:35 am - 9:42 am<br />
FP-13<br />
Psoriatic Intraepithelial Keratitis After Laser In Situ<br />
Keratomileusis Treatment<br />
Jose L. Rodriguez-Prats², Hector Morbelli²<br />
Ma. Joanna M. Rodriguez-Chan¹, Jorge L. Alio²<br />
¹Makati Medical Center, Philippines, ²Vissum Corporation<br />
Instituto Oftalmologico de Alicante, Spain<br />
Optics, Refraction, and Contact Lens<br />
9:43 am - 9:50 am<br />
FP-14<br />
The Anti-microbial Efficacy <strong>of</strong> Multipurpose Contact Lens<br />
Solutions on Standard Strains <strong>of</strong> Common Ocular Pathogens<br />
Eleonore B. Iguban, Juan Pablo R. Nanagas<br />
Roslyn F. De Mesa- Rodriguez<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines<br />
Chair: Raoul Paolo D. Henson, MD<br />
Co-Chair: Ma. Perla E. Duran, MD<br />
Orbit, Eyelids, Lacrimal, and Plastic<br />
10:01 - 10:08 am<br />
FP-15<br />
Superior Orbital Fissure Syndrome in Herpes Zoster<br />
Ophthalmicus<br />
Joanna Camille See Co, Ritsia A. Wastitiamurti<br />
Fatima University Medical Center, Philippines<br />
<strong>PAO</strong> Free Paper Program<br />
10:09 - 10:16 am<br />
FP-16<br />
Exophthalmometric Values <strong>of</strong> Adult Filipinos in a Rural Area:<br />
Barangay Bigaa, Cabuyao, Laguna<br />
Roland B. Bagnes, II, Evelyn S. Morabe, Anthony Christopher G. Ortiz,<br />
Ma. Melizza Theresa T. Ramirez, Jan Michael R. Reyes<br />
Jose R. Reyes Memorial Medical Center, Philippines<br />
10:17 - 10:24 am<br />
FP-17<br />
Preseptal Cellulitis, Orbital Cellulitis and Cavernous Sinus<br />
Thrombosis in Jose R. Reyes Memorial Medical Center<br />
Anne Marfe L. Tan, Anthony Christopher G. Ortiz<br />
Evelyn S. Morabe, Roland B. Bagnes, II<br />
Jose R. Reyes Memorial Medical Center, Philippines<br />
Pathology and Intraocular Tumors<br />
10:25 am - 10:32 am<br />
FP-18<br />
Your Common Sore Eyes or Something Endemic?<br />
Charl Marlo A. Jimenez<br />
DOH Eye Center East Avenue Medical Center, Philippines<br />
FREE PAPER SESSION 2<br />
<strong>Meeting</strong> Room 4-6<br />
9:05 - 11:30 am<br />
Chair: Danilo Constantino, MD<br />
Co-Chair: Roy Cagampan, MD<br />
Retina and Vitreous<br />
9:05 - 9:12 am<br />
FP-19<br />
Macular Measurements and Best Corrected Visual Acuity<br />
after Phacoemulsification in Diabetics with and without Partial<br />
Posterior Vitreous Detachment/ Focal Macular Traction<br />
Katrina Charisse T. Magno, Milagros H. Arroyo<br />
University <strong>of</strong> the Philippines-Philippine General Hospital<br />
Philippines<br />
9:13 - 9:20 am<br />
FP-20<br />
Full Field Electroretinography in Type 2 Diabetes Mellitus<br />
with No Diabetic Retinopathy and Mild Diabetic Retinopathy<br />
Institution: St. Luke’s Medical Center<br />
Rachelle G. Anzures, Leslie Gatchalian<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
2
<strong>PAO</strong> Free Paper Program<br />
9:21 - 9:28 am<br />
FP-21<br />
Measurement <strong>of</strong> Retinal Nerve Fiber Thickness in Patients<br />
with Diabetic Retinopathy<br />
Maria Cecilia Arenal, Romulo Aguilar<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
9:29 - 9:36 am<br />
FP-22<br />
Macular Pigment Optical Density <strong>of</strong> Healthy Eyes in University<br />
<strong>of</strong> Santo Tomas Hospital<br />
Ernesto D. Pablo, Jr.<br />
University <strong>of</strong> Sto. Tomas Hospital, Philippines<br />
9:37 - 9:44 am<br />
FP-23<br />
Surgical benefits <strong>of</strong> Endo-Illumination Filters on the Stellaris<br />
PC Surgical System<br />
Alex U. Pisig, Emerson Molina, Margarita Justine O. Bondoc<br />
Narciso F. Atienza, Jr.<br />
Cardinal Santos Medical Center, Philippines<br />
9:45 am- 9:52 am<br />
FP-24<br />
Outcomes <strong>of</strong> Retinoblastoma Patients with High-risk<br />
Histopathological Features in a Tertiary Hospital<br />
Patricia E. Cabrera, Gary JV. Mercado<br />
Rolando Enrique D. Domingo<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines<br />
9:53 am - 10:00 am<br />
FP-25<br />
Choroidal Melanoma in a Patient with Nevus <strong>of</strong> Ota<br />
Bryan Jason B. Atienza<br />
The Medical City, Philippines<br />
Chair: Vicente Victor D. Ocampo, Jr., MD<br />
Co-chair: Ellen Yu-Keh, MD<br />
Uveitis and Intraocular Inflammation<br />
10:12 am - 10:19 am<br />
FP-26<br />
Choroidal Tuberculosis: A Case Report<br />
Johanna T. Cervantes, Juan S. Lopez<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
3<br />
10:20 am - 10:27 am<br />
FP-27<br />
Chronic Sympathetic Ophthalmia: A Case Report<br />
Margarita Justine O. Bondoc, Analyn Suntay-Guerrero, Emerson<br />
Jay B. Molina, Alex U. Pisig, Egidio Jose S. Fortuna, Kristine Corpus<br />
Cardinal Santos Medical Center, Philippines<br />
FREE PAPER SESSION 3<br />
<strong>Meeting</strong> Rooms 4-6<br />
1:30 - 4:00 pm<br />
Chair: Rigo Daniel Reyes, MD<br />
Co-Chair: Ernesto Pangalangan, Jr., MD<br />
Glaucoma<br />
10:28 am - 10:35 am<br />
FP-28<br />
Ocular Toxoplasmosis among Filipino Patients seen at the<br />
East Avenue Medical Center: Clinical Manifestation and<br />
Effectiveness <strong>of</strong> Treatment<br />
Majourette Dy Varela, Jessica Marie R. Abaño<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
10:36 am - 10:43 am<br />
FP-29<br />
Intermediate Uveitis as an Initial Presentation <strong>of</strong> Sarcoidosis<br />
in an Adolescent Male<br />
Jacqueline T. Mupas, Jessica Marie R. Abaño<br />
University <strong>of</strong> Santo Tomas Hospital, Philippines<br />
10:44 am - 10:51 am<br />
FP-30<br />
A Retrospective Study <strong>of</strong> the Incidence, Indications and<br />
Outcomes <strong>of</strong> Nd:YAG Capsulotomy in Eyes Implanted with<br />
and Accommodating IOL<br />
Angela Adelaida Samano¹, Rosalie Mae M. Reyes²<br />
¹Cardinal Santos Medical Center, ²Asian Eye Institute, Philippines<br />
10:52 am - 10:59 am<br />
FP-31<br />
Refractive and Visual Outcomes <strong>of</strong> Surgical Treatments for<br />
High Myopia Patients<br />
Ma. Rachelle Katrina C. Solis, Robert Edward T. Ang<br />
Cardinal Santos Medical Center, Philippines<br />
1:30 pm - 1:37 pm<br />
FP-32<br />
Preliminary Report on the Incidence <strong>of</strong> Steroid-induced Ocular<br />
Hypertension in Patients in a Tertiary Hospital: A 5-year<br />
Prospective Study<br />
Victoria Anne A. Yao, Ma. Margarita Lat-Luna, Juan S. Lopez<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines
1:38 pm - 1:45 pm<br />
FP-33<br />
Comparison <strong>of</strong> Trabeculectomy with Mitomycin-C and<br />
Glaucoma Drainage Device Implantation in Glaucoma<br />
Management after Penetrating Keratoplasty<br />
Meliza Katrina B. Agulto, Rainier Victor A. Covar<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines<br />
1:46 pm - 1:53 pm<br />
FP-34<br />
Factors that Affect the Iris Thickness Amongst Filipinos in<br />
View <strong>of</strong> Angle Closure Glaucoma<br />
Ritsia A. Wastitiamurti<br />
Fatima University Medical Center, Philippines<br />
1:54 pm - 2:01 pm<br />
FP-35<br />
Malignant Glaucoma Post Pars Plana Vitrectomy with<br />
Intraocular Lens Retrieval<br />
Ian Ben M. Batcagan<br />
Quirino Memorial Medical Center, Philippines<br />
2:02 pm - 2:09 pm<br />
FP-36<br />
Correlation between the Average Retinal Nerve Fiber Layer<br />
Thickness and Rim Area Value <strong>of</strong> the Cirrus OCT with the<br />
Humphrey Visual Field Index Value<br />
Andrei P. Martin<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
2:10 pm - 2:17 pm<br />
FP-37<br />
The Effect <strong>of</strong> Direct Cold Compress on Intraocular Pressure in<br />
Healthy Subjects<br />
Niccolo Zandro Valencia, Mario M. Yatco, Ian Ethelbert Dy<br />
University <strong>of</strong> Sto. Tomas Hospital, Philippines<br />
Optics, Refraction, and Contact Lens<br />
2:18 pm - 2:25 pm<br />
FP-38<br />
Retinal Nerve Fiber Layer Measurements in Myopic Subjects<br />
Dennis L. Del Rosario, Mario M. Yatco<br />
University <strong>of</strong> Sto. Tomas Hospital, Philippines<br />
Chair: Andrea Kristina M. Pajarillo, MD<br />
Co-Chair: Cheryl C. Tamayo, MD<br />
<strong>PAO</strong> Free Paper / Poster Presentation Program<br />
Pediatric Ophthalmology and Strabismus<br />
2:37 pm - 2:44 pm<br />
FP-39<br />
Epidemiology and Visual Outcomes <strong>of</strong> Pediatric Ocular<br />
Trauma Cases in a Tertiary Hospital<br />
Theresa Gladiola B. Merca, Marissa N. Valbuena<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines<br />
2:45 pm - 2:52 pm<br />
FP-40<br />
Ophthalmologic Findings in Hunter Syndrome<br />
Frances Marie DC. Roa, Marissa N. Valbuena<br />
Mary Ann R. Abacan, Mary Anne D. Chiong<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines<br />
2:53 pm - 3:00 pm<br />
FP-41<br />
A Preliminary Report on the Efficacy <strong>of</strong> Occlusion Therapy<br />
Versus Observation for Pediatric Intermittent Exotropia: A<br />
Single-Blind Randomized Controlled Trial<br />
Ma Patricia Therese R. Fellizar, Marissa N. Valbuena<br />
Melissa Anne M. Santos<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines<br />
3:01 pm - 3:08 pm<br />
FP-42<br />
Eventual Outcomes <strong>of</strong> Retinopathy <strong>of</strong> Prematurity Screening<br />
at a Tertiary Government Hospital: A Five Year Study<br />
Emmeline M. Alvarez, Ricardo Ventura<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
3:09 pm - 3:16 pm<br />
FP-43<br />
Effect <strong>of</strong> Pediatric Eye Screening Checklist and Training on<br />
Ophthalmology Referrals in QMMC, a 1-year Study<br />
Ian Ben M. Batcagan<br />
Quirino Memorial Medical Center, Philippines<br />
3:17 pm - 3:24 pm<br />
FP-44<br />
Four Year Prevalence and Outcome <strong>of</strong> Initial Screening for<br />
Retinopathy <strong>of</strong> Prematurity (ROP) at the Clinical Division <strong>of</strong> a<br />
Tertiary Hospital<br />
James Rommet Luz, Marcelino D. Banzon, Almira A. Manzano<br />
University <strong>of</strong> Sto. Tomas Hospital, Philippines<br />
4
<strong>PAO</strong> Free Paper / Poster Presentation Program<br />
3:25 pm - 3:32 pm<br />
FP-45<br />
Cycloplegic Effectiveness <strong>of</strong> Single-Dose Atropine 0.5%<br />
Compared with Three-Day Atropinization in Determining<br />
Error <strong>of</strong> Refraction in Children<br />
Anna Theresa G. Fernando, Fay Charmaine S. Cruz<br />
University <strong>of</strong> the East Ramon Magsaysay Memorial Medical<br />
Center Inc., Philippines<br />
POSTER PRESENTATIONS<br />
External Disease and Cornea<br />
PP-1<br />
Bilateral Peripheral Ulcerative Keratitis in an Anti-nuclear<br />
Antibody (ANA) Positive 16 year-old Female: A Case Report<br />
Abigail O. Panganiban, Kate Concepcion-Torio<br />
Jennifer Aurea S. Sarmiento<br />
Cardinal Santos Medical Center, Philippines<br />
PP-2<br />
Sebaceous Gland Carcinoma Masquerading as a Large<br />
Molluscum Contagiosum Nodule<br />
Emerson Jay B. Molina, Jacinto U. Dy-Liacco,<br />
Jennifer Aurea S. Sarmiento<br />
Cardinal Santos Medical Center, Philippines<br />
PP-3<br />
Effect <strong>of</strong> Topical Anesthetic in Pupillary Dilation<br />
in Filipino Eyes<br />
Joyce Ann L. Lo, Richard Raymund L. Nepomuceno<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
PP-4<br />
A Case <strong>of</strong> Cogan’s Syndrome in the Philippines<br />
Ann Krystine C. Balmaceda, Jessica Marie R. Abaño<br />
Rene Louie C. Gutierrez<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
PP-5<br />
A Case <strong>of</strong> Cogan Syndrome<br />
Jose Mari G. Sagmit, Jacinto S. Bautista, Jr., Noel Castillo<br />
Hospital <strong>of</strong> the Infant Jesus, Philippines<br />
PP-6<br />
Prevalence <strong>of</strong> Dry Eye Syndrome and Diabetic Retinopathy<br />
in Type 2 Diabetes in the Hospital <strong>of</strong> the Infant Jesus<br />
Ophthalmology Outpatient Department<br />
Jamil Laurence R. So-Reyes, Jacinto S. Bautista, Jr.<br />
Hospital <strong>of</strong> the Infant Jesus, Philippines<br />
5<br />
Glaucoma<br />
PP-7<br />
Axenfeld -Rieger Syndrome: Case Report<br />
Reggie R. Revilla, Ian Benjamin T. Hizon<br />
University <strong>of</strong> the East Ramon Magsaysay Memorial Medical<br />
Hospital, Philippines<br />
PP-8<br />
Treatment Option for the Management <strong>of</strong> Neovascular<br />
Glaucoma<br />
Mark Gil J. Marasigan, Ronaldo Jarin<br />
Quirino Memorial Medical Center, Philippines<br />
Lens and Cataract Surgery<br />
PP-9<br />
Comparison <strong>of</strong> Axial Length Measurements Taken by<br />
Partial Optical Coherence Interferometry (IOL Master®) and<br />
Immersion Scan<br />
Jessica De Leon, Richard Raymund L. Nepomuceno<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
PP-10<br />
Effect <strong>of</strong> Heat from Gaseous Sterilization on Antimicrobial<br />
Efficacy <strong>of</strong> Moxifloxacin 0.5% Eye Drops<br />
Mark Christian R. Rivera<br />
University <strong>of</strong> Santo Tomas Hospital, Philippines<br />
PP-11<br />
Comparison <strong>of</strong> the Sealing Ability Between the Wong Incision<br />
and Standard Stromal Hydration <strong>of</strong> Clear Cornea Incisions in<br />
Phacoemulsification Surgery: An Animal Eye Study<br />
Raymond Nelson C. Regalado, Ruben Lim Bon Siong<br />
Jay Marianito S. Vicencio, Lee Verzosa<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
PP-12<br />
Evaluation <strong>of</strong> the Effectiveness <strong>of</strong> the Angled Sinskey Hook<br />
for Vertical Quick-Chop Nucleotomy in Phacoemulsification<br />
Lenard Paul Concepcion, Antonio Say, Alex Sua<br />
University <strong>of</strong> Santo Tomas Hospital, Philippines<br />
Neuro-ophthalmology<br />
PP-13<br />
Ocular Myasthenia Gravis with Probable Thymoma in a<br />
Prepubertal Male<br />
Jennifer Aurea S. Sarmiento, Karen B. Reyes<br />
Cardinal Santos Medical Center, Philippines
PP-14<br />
A Review <strong>of</strong> Prevalence <strong>of</strong> Neuro-Ophthalmic Disorders in a<br />
Government Tertiary Hospital in Quezon City, Philippines -<br />
A 4 years Study<br />
Ryan R. Bacani<br />
DOH Eye Center East Avenue Medical Center, Philippines<br />
PP-15<br />
Ptosis and Ophthalmoplegia in a 56 Year Old Post Corneal<br />
Transplant Patient: A Case Report<br />
Kristine Belen Pascua, Leonides Karlo C. Melendres, III<br />
DOH Eye Center- East Avenue Medical Center, Philippines<br />
PP-16<br />
Unilateral Optic Nerve Atrophy in a Child with<br />
Schizencephaly: A Case Report<br />
Denver K. Ching, Leonides Karlo Melendres, III<br />
DOH Eye Center East Avenue Medical Center, Philippines<br />
PP-17<br />
Third Nerve Palsy Probably Ischemic: A Non Resolving<br />
Palsy in a 58 Year Old Male<br />
Abegaile O. Bartolome, Erwin D. Palisoc, Emilio Macias, III,<br />
Evelyn S. Morabe<br />
Jose R. Reyes Memorial Medical Center, Philippines<br />
PP-18<br />
Post Operative Abducens Nerve Palsy<br />
Caesar Percival F. Sunio, Karen B. Reyes<br />
Ospital ng Makati, Philippines<br />
PP-19<br />
Dengue Fever with Optic Neuropathy<br />
Pius Jonas F. Ocampo, Buenjim Mariano<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
PP-20<br />
Giant Cell Arteritis: A Case Report <strong>of</strong> a 77 year old Female<br />
Almira A. Manzano, Roberto Uy<br />
University <strong>of</strong> Santo Tomas Hospital, Philippines<br />
Optics, Refraction, and Contact Lens<br />
PP-21<br />
Comparison <strong>of</strong> Visual and Refractive Outcomes Using a<br />
Microkeratome Versus Femtosecond Laser in Creating a<br />
Flap for Corneal Inlay Implantation<br />
Vincent Joseph Corpus, Robert Edward T. Ang<br />
Cardinal Santos Medical Center, Philippines<br />
Poster Presentation Program<br />
Orbit, Eyelids, Lacrimal, and Plastic<br />
PP-22<br />
Beveled Osteotomies in Lateral Orbitotomy Using a<br />
Customized Rotating Bone Saw for Orbital Neoplasms<br />
Ma. Donna D. Santiago<br />
Far Eastern University - Nicanor Reyes Memorial Foundation,<br />
Philippines<br />
PP-23<br />
Mixed Capillary and Cavernous Hemangioma:<br />
A Case Report<br />
Jesilyn Penny E. Lim, Ma. Donna D. Santiago<br />
Far Eastern University-Nicanor Reyes Medical Foundation<br />
Medical Center, Philippines<br />
PP-24<br />
Recurrent Orbital Inflammatory Disease in a<br />
Pediatric Patient<br />
Jerica Paula D. Berdon, Ma. Donna D. Santiago<br />
Far Eastern University-Nicanor Reyes Medical Foundation<br />
Medical Center, Philippines<br />
PP-25<br />
The Efficacy <strong>of</strong> Topical Mitomycin-C in the Prevention <strong>of</strong><br />
Recurrence <strong>of</strong> Conjunctival Squamous Cell Carcinoma in a<br />
36-year Old Male<br />
Kate Concepcion-Torio, Ma. Rachelle Katrina C. Solis,<br />
Jo Anne P. Hernandez<br />
Cardinal Santos Medical Center, Philippines<br />
PP-26<br />
Wide Excision <strong>of</strong> a Large Upper Lid Sebaceous Gland<br />
Carcinoma with Reconstruction Using the Modified Cutler-<br />
Beard Technique<br />
Emerson Jay B. Molina, Alex U. Pisig,<br />
Margarita Justine O. Bondoc, Jo Anne P. Hernandez<br />
Cardinal Santos Medical Center, Philippines<br />
PP-27<br />
Pfeiffer Syndrome-A Case Report<br />
Christine S. Siguan, Marissa N. Valbuena,<br />
Prospero Ma. C. Tuaño<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines<br />
PP-28<br />
Eyelid Neurilemmoma: A Vanishing Rarity<br />
Neal Vincent L. Torre, Fatima G. Regala<br />
DOH Eye Center East Avenue Medical Center, Philippines<br />
6
PP-29<br />
A Case <strong>of</strong> Basosquamous Carcinoma <strong>of</strong> the Central and<br />
Midface Area in a 62 year old Filipino Male<br />
Rhyan Francis T. Monsanto, Charmaine Y. Ang<br />
Fatima G. Regala<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
PP-30<br />
A Case Report on an Unusual Intraorbital Foreign Body<br />
Jessica Guzman, Fatima G. Regala, Charmaine Y. Ang<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
PP-31<br />
Bilateral Proptosis with Visual Loss: A Case Report<br />
J. Rotsen Evaristo, Fatima G. Regala<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
PP-32<br />
Carcinosarcoma in a Newborn<br />
Aimee C. Ng Tsai<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
PP-33<br />
Comparative Study <strong>of</strong> Using Dermal Fat Graft Alone and<br />
Dermal Fat Graft with an Orbital Implant in Children<br />
Majourette Dy Varela, Fatima G. Regala, Charmaine Y. Ang<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
PP-34<br />
Use <strong>of</strong> a Modified Metal Guide <strong>of</strong> a Bicanalicular Intubation<br />
Stent in Transected Canalicular Repair<br />
Marco A. Tumalad, Charmaine Y. Ang, Fatima G. Regala<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
PP-35<br />
Cavernous Hemangioma <strong>of</strong> the Orbit:<br />
An Unusual Presentation<br />
Clarissa H. Tuliao, Anthony Christopher G. Ortiz,<br />
Evelyn S. Morabe, Ma. Lourdes R. Nañagas<br />
Jose R. Reyes Memorial Medical Center, Philippines<br />
PP-36<br />
Sebaceous Gland Carcinoma <strong>of</strong> the Eyelid Presenting as a<br />
Chalazion: A Case Report<br />
Pearl Trisha M. Padilla, Leonardo R. Mangubat<br />
Makati Medical Center, Philippines<br />
7<br />
Poster Presentation Program<br />
PP-37<br />
Orbital Metastasis Arising From Adenocarcinoma<br />
<strong>of</strong> the Lung<br />
Bernardo Joaquin Tuaño, Yvette Marie Santiago<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
PP-38<br />
Spontaneous Resolution <strong>of</strong> Dilated Superior Ophthalmic<br />
Vein in a Patient with Indirect Carotid-cavernous<br />
Sinus Fistula<br />
Karen Joyce G. Castro, Prospero Ma. C. Tuaño<br />
St Luke’s Medical Center, Philippines<br />
PP-39<br />
Two-Stage Reconstruction <strong>of</strong> Upper and Lower Anterior<br />
Lamellar Eyelid Defect after Excision <strong>of</strong> Intradermal Nevus<br />
Pius Jonas F. Ocampo, Mary Rose Pe-Yan<br />
St. Luke’s Medical Center, Philippines<br />
PP-40<br />
Painful Ophthalmoplegia<br />
Honeylen Maryl Tiu Teo, Prospero Ma. C. Tuaño<br />
Buenjim Mariano<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
PP-41<br />
Canalicular Reconstruction in Long Standing Healed<br />
Canalicular Laceration<br />
Simeon Arni A. Pagdanganan, Reynaldo M. Javate<br />
University <strong>of</strong> Santo Tomas Hospital, Philippines<br />
PP-42<br />
Microendoscopic Recanalization with Silicone Intubation<br />
for the Treatment <strong>of</strong> Canalicular and Primary Acquired<br />
Nasolacrimal Duct Obstruction<br />
Armida L. Suller, Reynaldo M. Javate, Raul T. Cruz, Jr.<br />
University <strong>of</strong> Santo Tomas Hospital, Philippines<br />
Pathology and Intraocular Tumors<br />
Adenoid Cystic Carcinoma <strong>of</strong> the Lacrimal Gland:<br />
A Case Report<br />
Mamerto G. Capero, Jr., Anthony Christopher G. Ortiz, Evelyn S.<br />
Morabe, Ma. Lourdes M. Nañagas<br />
Jose R. Reyes Memorial Medical Center, Philippines<br />
PP-44<br />
Primitive Neuroectodermal Tumour <strong>of</strong> the Orbit in a 14 Year<br />
Old Male with Absolute<br />
Glaucoma Post Evisceration: A Case Report<br />
Manuel Benjamin B. Ibañez, IV, Leonardo R. Mangubat,<br />
Ramon Mario Ongsiako<br />
Makati Medical Center, Philippines
Pediatric Ophthalmology and Strabismus<br />
PP-45<br />
A Case <strong>of</strong> Bilateral Persistent Fetal Vasculature in a<br />
Premature Infant<br />
Arturo B. Capulong, Emilio Macias, III, Evelyn Morabe<br />
Jose R. Reyes Memorial Medical Center, Philippines<br />
PP-46<br />
Moebius Syndrome Associated with Exposure<br />
to Misoprostol<br />
JC Martin S. Cabrera, Bibhuti R. Thapa, Emilio L. Macias, III,<br />
Evelyn S. Morabe, Ma. Lourdes Nañagas<br />
Jose R. Reyes Memorial Medical Center, Philippines<br />
PP-47<br />
Strabismus Surgery in a Child with Moebius Syndrome<br />
Maureen M. Resonable, Michelle M. Hernandez<br />
Ospital ng Maynila Medical Center, Philippines<br />
PP-48<br />
Prevalence <strong>of</strong> Amblyopia in School Aged Children in<br />
Maybunga Elementary School<br />
Airene M. Oloroso<br />
Rizal Medical Center, Philippines<br />
PP-49<br />
Self-inflicted, Traumatic Disinsertion <strong>of</strong> the Lateral Rectus:<br />
A Case Report<br />
Patricia Isabel C. Manalastas, Fay Charmaine S. Cruz<br />
University <strong>of</strong> the East Ramon Magsaysay Memorial Medical<br />
Hospital, Philippines<br />
Retina and Vitreous<br />
PP-50<br />
Neuritis and Neuro-retinitis as Initial Presentations <strong>of</strong> HIV<br />
Elenor Reina S. Aquino, Jessica Marie R. Abaño, Jocelyn Sy<br />
University <strong>of</strong> Santo Tomas Hospital, Philippines<br />
PP-51<br />
Bilateral Serous Retinal Detachment in Toxemia <strong>of</strong><br />
Pregnancy: A Case Series<br />
Mayjane Joan G. Tumulak, Jocelyn Sy<br />
DOH Eye Center East Avenue Medical Center, Philippines<br />
PP-52<br />
Choroidal Hemangioma: A Case Report<br />
Jan Carlo Y. Alegre, Jocelyn Sy<br />
DOH Eye Center East Avenue Medical Center, Philippines<br />
Poster Presentation Program<br />
PP-53<br />
Central Retinal Artery Occlusion in the Young<br />
Erica Blanca Daquil<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
PP-54<br />
Best’s Vitelliform Macular Dystrophy with Normal EOG:<br />
A Case Report<br />
Nikki Doreen Angbue Te<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
PP-55<br />
Neovascular Glaucoma and Exudative Retinal Detachment<br />
in a Young Male: A Case Report<br />
Mark Angelo B. Hosaka<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
PP-56<br />
Treatment <strong>of</strong> Polypoidal Choroidal Vasculopathy<br />
Paul Samuel Del Mundo, Johanna T. Cervantes,<br />
Pearl Tamesis-Villalon<br />
St. Luke’s Medical Center International Eye Institute, Philippines<br />
PP-57<br />
Retinopathy <strong>of</strong> Prematurity Screening in a Tertiary Care<br />
Center: Incidence and Percentage <strong>of</strong> Referrals<br />
by Neonatologists<br />
Anna Karina D. Leopando<br />
The Medical City, Philippines<br />
PP-58<br />
Endogenous Endophthalmitis Secondary to Gram Negative<br />
Bacteremia (Klebsiella spp) with Secondary Urinary<br />
Tract Infection<br />
Jocelyn Therese M. Remo, Jose Luis G. De Grano,<br />
Ian Benjamin T. Hizon<br />
University <strong>of</strong> the East Ramon Magsaysay Memorial Medical<br />
Center, Philippines<br />
PP-59<br />
Increased Intraocular Pressure after Anti-VEGF Injection –<br />
QMMC Experience<br />
Lyndon D. Edaño<br />
Quirino Memorial Medical Center, Philippines<br />
8
Poster Presentation Program / Oral Free Papers<br />
Uveitis and Intraocular Inflammation<br />
PP-60<br />
Vogt-Koyanagi-Harada Syndrome: A Case Report<br />
Anna Francesca B. Bayrante, Jessica Marie R. Abaño<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
PP-61<br />
Ocular Involvement in Adamantiades-Beh’et Disease (ABD)<br />
Aileen Viguilla, Egidio Jose S. Fortuna<br />
The Medical City, Philippines<br />
DAY 3 • SUNDAY, DECEMBER 2, <strong>2012</strong><br />
Function Room 1<br />
SVC – 2<br />
CATARACT BREAKFAST SURGICAL VIDEO CONFERENCE<br />
9:00 – 9:07 am<br />
Lensectomy with Scleral Suturing <strong>of</strong> Cionni Ring with In-thebag<br />
Lens Implantation for Ectopia Lentis Secondary to<br />
Marfan Syndrome<br />
Reginald Robert Tan, Jay Marianito S. Vicencio<br />
Objective: To describe the surgical management and<br />
postoperative outcomes <strong>of</strong> a case <strong>of</strong> bilateral ectopia lentis<br />
secondary to Marfan syndrome.<br />
Methods: A 19 year-old female complained <strong>of</strong> progressive<br />
blurring <strong>of</strong> vision since early childhood. Patient was diagnosed<br />
with bilateral ectopia lentis secondary to Marfan syndrome. Best<br />
corrected visual acuity (BCVA) on the right and left eyes were<br />
counting fingers and 20/50, respectively. Slit lamp examination<br />
showed lens bissecting the pupil in both eyes. The patient<br />
underwent bilateral lensectomy with scleral fixation <strong>of</strong> Cionni<br />
modified capsular tension ring (MCTR) with in-the-bag intraocular<br />
lens implantation.<br />
Results: No major intraoperative and post-operative complications<br />
were met. On the first post-operative day, the vision was 20/400<br />
on the right eye and 20/32 on the left. The right eye showed mild<br />
corneal edema. One month post-operatively, visual acuity was<br />
still 20/400 and and 20/32, for the right and left eyes, respectively.<br />
In the two eyes, the corneas were clear. The lack <strong>of</strong> improvement<br />
in VA <strong>of</strong> the right eye was attributed to ambylopia acquired during<br />
childhood.<br />
Conclusions: Lensectomy with scleral fixation <strong>of</strong> capsular<br />
tension ring with in-the-bag intraocular lens implantation may<br />
be a safe procedure in ectopia lentis secondary to Marfan’s with<br />
good post-operative results. However, the procedure is not easy<br />
to perform and will need expertise on the part <strong>of</strong> the surgeon.<br />
Key Words: Capsular tension ring, Marfan syndrome, Scleral<br />
fixation, Lensectomy, Ectopia Lentis<br />
9<br />
DAY 1 • FRIDAY, NOVEMBER 30, <strong>2012</strong><br />
Function Room 2<br />
9:05 am – 11:30 am<br />
SY – 2<br />
NEURO-OPHTHALMOLOGY SYMPOSIUM<br />
Chair: Lourdes T. Ang, MD<br />
Co-chair: Rolan Mangahas , MD<br />
10:51am – 11:05 am<br />
FP-1<br />
Efficacy <strong>of</strong> Vitamin B in Preventing Color Vision Abnormalities<br />
Among Patients Undergoing DOTS for Tuberculosis<br />
Jan Michael R. Reyes, Ma. Melizza Theresa T. Ramirez,<br />
Anne Marfe L. Tan, Roland B. Bagnes, II, Evelyn S. Morabe,<br />
Emerson M. Cruz, Ma. Lourdes R. Nañagas<br />
Jose R. Reyes Memorial Medical Center, Philippines<br />
Objective: To determine if Vitamin B supplementation can<br />
prevent the development <strong>of</strong> color vision abnormalities in patients<br />
taking Ethambutol as part <strong>of</strong> DOTS for tuberculosis.<br />
Methods: A randomized, placebo-controlled, double-blind<br />
clinical trial was conducted among newly diagnosed category-1<br />
tuberculosis patients enrolled in DOTS health centers in the third<br />
district <strong>of</strong> Manila from June 2011 to August <strong>2012</strong>. Before starting<br />
therapy, the participants underwent complete eye evaluation.<br />
Baseline Color vision was tested using the Ishihara Color Vision<br />
Plates (Ishihara), Farnsworth Panel D-15 (FD 15), and Lanthony<br />
Desaturated D-15 tests. Only subjects who passed the three color<br />
vision tests were included in the study, and divided into 2 groups:<br />
Group A received vitamin B, and Group B received a placebo.<br />
Follow up color vision testing was done monthly for 3 months.<br />
Results: There were 105 patients included in the study, 77 males,<br />
and 28 females, age ranging from 16- to 68, with a mean <strong>of</strong> 37.43<br />
patients received VIT B (GRP A) and 62 received placebo, (GRP<br />
B) After one month <strong>of</strong> DOTS, 5 <strong>of</strong> 43 patients (11. 6 %) in GRP<br />
A developed color vision abnormalities, while 10 <strong>of</strong> 62 patients<br />
(16.1%) developed color vision abnormalities in the placebo<br />
group. The abnormalities were only detected using the Lanthony<br />
desaturated test. The absolute risk reduction (ARR) <strong>of</strong> color<br />
vision abnormalities by VIT B supplementation was 4.5%, with<br />
the number needed to treat (NNT) = 23. After the second month<br />
<strong>of</strong> therapy, ARR was 7.4%, and NNT = 14. ARR was highest in<br />
the third month at 8.3%, with a corresponding improved NNT <strong>of</strong><br />
12. Among patients who developed color vision abnormalities,<br />
reversal <strong>of</strong> the abnormalities was observed in 80% <strong>of</strong> 5 subjects<br />
in Group A while only 40% <strong>of</strong> 10 patients improved in Group<br />
B. By the third month <strong>of</strong> treatment, all those in GRP A already<br />
had normal color vision. On the other hand, 40% <strong>of</strong> those in the<br />
placebo group still showed abnormal color vision. The difference<br />
<strong>of</strong> the two groups is statistically significant.<br />
Conclusions: This study shows that vitamin B complex is<br />
effective in reducing the risk <strong>of</strong>, and in reversing cases <strong>of</strong> color<br />
vision abnormalities among patients undergoing DOTS therapy for
tuberculosis. It is therefore recommended that all patients undergoing<br />
therapy be given Vit B supplementation. This is especially true in<br />
those receiving higher doses <strong>of</strong> the drug or prolonged treatment due<br />
to advanced or resistant disease.<br />
Key Words: Absolute risk reduction, Fansworth D15,<br />
Ishihara, Lanthony<br />
11:06 am – 11:14 am<br />
FP-2<br />
A Comparison <strong>of</strong> Visual Outcomes in Optic Neuritis Patients<br />
Treated with Intravenous Dexamethasone and<br />
Methylprednisolone at a Tertiary Hospital : A Retrospective<br />
Study<br />
Shalam Siao, Lee Allen D. Cloma, Leonides Karlo C. Melendres, III<br />
DOH Eye Center East Avenue Medical Center, Philippines<br />
Objective: To compare rate and amount <strong>of</strong> visual recovery in<br />
Acute Optic Neuritis patients treated with IV Dexamethasone<br />
(8mg Loading Dose, 4mg every eight hours X11 doses) and<br />
IV Methylprednisolone 250mg every 6 hours for three days. To<br />
provide a clinical pr<strong>of</strong>ile <strong>of</strong> patients treated at Neuro-Ophtha clinic<br />
as to age and sex, laterality <strong>of</strong> visual affectation, and to identify<br />
any associated systemic illness<br />
Methods: A Retrospective chart review <strong>of</strong> patients seen at the<br />
Neuro-ophthalmology Clinic at a tertiary hospital from year 2004-<br />
<strong>2012</strong>. Visual Acuity between treatment groups was recorded at<br />
the time <strong>of</strong> initial consult, after initiation <strong>of</strong> treatment and at one<br />
month follow-up. Gross color testing was also done together with<br />
an Ishihara Test.<br />
Results: Initial results showed that total <strong>of</strong> 24 patients were seen<br />
and diagnosed as acute optic neuritis cases. There was a 7:17<br />
Female to Male ratio noted with age range <strong>of</strong> 6-52 years <strong>of</strong> age<br />
among affected cases. 37.5% <strong>of</strong> cases had bilateral involvement.<br />
No cases have been reported to have comorbidities. Fifteen<br />
cases received IV dexamethasone treatment. 8 cases received<br />
IV methylprednisolone, a case received oral methylprednisolone<br />
and 3 cases did not receive any treatment. Visual acuity <strong>of</strong> the<br />
IV Dexamethasone group ranged from >+1.0 LogMar- +0.7 prior<br />
to treatment. Post treatment, visual acuity ranged from >+1.0<br />
Logmar-+0.6, by one month follow-up half <strong>of</strong> the group had<br />
vision ranging +0.2-0.1 Logmar. In the Methylprednisolone group,<br />
pretreatment visual acuity ranged from >+1.0-0.2 Logmar. By the<br />
end <strong>of</strong> IVtreatment 50% <strong>of</strong> cases had visual acuity <strong>of</strong> +0.2-0.1<br />
Log Mar.<br />
Conclusion: Improvement <strong>of</strong> visual acuity was noted in both<br />
treatment groups after initiation <strong>of</strong> treatment. It was observed that<br />
in the Methylprednisolone group that 50% achieved improved VA<br />
to Logmar +0.2-0.1 immediately post treatment as compared to<br />
only 33.3% <strong>of</strong> cases in the dexamethasone group.<br />
Key Words: methylprednisolone, visual recovery, Optic Neuritis<br />
DAY 2 • SATURDAY, DECEMBER 1, <strong>2012</strong><br />
Function Room 1<br />
SY – 10<br />
PUBLIC HEALTH OPHTHALMOLOGY SYMPOSIUM<br />
4:40 pm – 4:47 pm<br />
FP-3<br />
Oral Free Papers<br />
Barriers to the Utilization <strong>of</strong> Eye Care Services in a<br />
Rural Setting<br />
Mateo Andro R. Geronimo, Ma. Victoria A. Rondaris<br />
DOH Eye Center , East Avenue Medical Center , Philippines<br />
Objective: To determine the perceived barriers, attitudes and<br />
socio-cultural aspects <strong>of</strong> eye health and eye care services in a<br />
remote rural community in the Philippines.<br />
Methods: This is a qualitative study that deals with two focus<br />
groups (group I= 9 participants, group II= 7 participants) comprising<br />
<strong>of</strong> residents from a rural community in the Philippines. The<br />
population came from Sitio Mainit, Bgy. Pulang Bato, San Juan,<br />
Batangas, a relatively remote, land-locked community located<br />
around 4km from the highway via rough road. The focus group<br />
discussion follows a structured but open ended questionnaire.<br />
Discussions are videotaped and transcribed, and finally analyzed<br />
using a thematic framework approach. Questions deal mainly with<br />
experiences regarding eye symptoms, awareness <strong>of</strong> the need for<br />
consult, person or place <strong>of</strong> consult, reason for consult, and the<br />
different barriers encountered regarding eye care.<br />
Results: Sixteen Filipino residents from Bgy Pulang Bato, San<br />
Juan Batangas, aged 34 to 75 (mean: 52.9) were divided into two<br />
gender specific focus groups (Group I: female, group II: male).<br />
100% <strong>of</strong> the participants cited the major perceived barrier was<br />
cost, regardless if it was transportation related, opportunity cost,<br />
or health care costs. However, during probing, the main barrier<br />
noted by the investigators was not financial in nature, instead, it<br />
was the lack <strong>of</strong> awareness <strong>of</strong> their conditions. 14/16 participants<br />
(87.5%) had no initial perceived need for consult, until specific<br />
symptoms or conditions were elaborated to them.<br />
Conclusion: There are multiple barriers that may affect the<br />
healthcare behaviors and attitudes <strong>of</strong> patients. All <strong>of</strong> these<br />
features must be considered when planning to address the eye<br />
health care issues <strong>of</strong> a certain locale, where even the awareness<br />
<strong>of</strong> symptoms and disease entities may not be realized. The further<br />
development <strong>of</strong> awareness campaigns, coupled with a more<br />
intensive health education system may be necessary to increase<br />
the uptake <strong>of</strong> eye care services <strong>of</strong> our centers.<br />
Key Words: Barriers, eye health, focus groups, health seeking<br />
behavior<br />
10
Oral Free Papers<br />
4:47 pm – 4:54 pm<br />
FP-4<br />
Psychometric Analysis <strong>of</strong> the 25-Item National Eye Institute<br />
Visual Function Questionnaire (NEI VFQ-25) Filipino Version<br />
Lawrence Joseph S. Valdez , Ma. Victoria A. Rondaris<br />
DOH Eye Center , East Avenue Medical Center , Philippines<br />
Objective: To validate a Filipino version <strong>of</strong> the National Eye<br />
Institute Visual Function Questionnaire (NEI VFQ-25).<br />
Methods: A two-step process was used to validate the NEI VFQ-<br />
25. First, translation <strong>of</strong> the questionnaire to Filipino was performed<br />
by two ophthalmology residents, two ophthalmic nurses and four<br />
(two forward and two backward) linguists from the University<br />
<strong>of</strong> the Philippines, Sining ng Wikang Filipino, using forwardbackward-forward<br />
translation. Inconsistencies were noted and<br />
revised. The final Filipino NEI VFQ-25 was then pretested on ten<br />
patients in a tertiary government hospital. Second, psychometric<br />
analysis was performed on the response to the questionnaire <strong>of</strong><br />
ninety six patients from the eye center <strong>of</strong> a tertiary government<br />
hospital. Internal consistency <strong>of</strong> the tool was then measured by<br />
Cronbach’s alpha for each subscale, and was used as an index<br />
<strong>of</strong> reliability. Evaluation <strong>of</strong> the questionnaire’s construct validity<br />
was performed using factor analysis. Subsequently, convergent<br />
and discriminant validities were calculated by means <strong>of</strong> multi-trait<br />
analysis.<br />
Results: Respondents mean age was 50.14 (SD 17.87), 55%<br />
were male and 32.29% had a college degree. Two patient groups<br />
were utilized, Group 1 included 71 participants with a single<br />
cause <strong>of</strong> visual impairment (22 cataract; 19 diabetic retinopathy;<br />
15 glaucoma; 3 uveitis; 4 microbial keratitis; 2 retinal detachment;<br />
4 corneal leukoma and 2 post penetrating keratoplasty patients).<br />
Group 2 included 25 healthy controls. The questionnaire’s internal<br />
consistency was high in most subscales, with a Cronbach’s alpha<br />
range from 0.62-0.91. All items passed the convergent and<br />
discriminant validity tests. Comparison between the subscale<br />
scores <strong>of</strong> patients and controls is statistically significant with a<br />
p-value < 0.001.<br />
Conclusion: The Filipino version <strong>of</strong> the NEI-VFQ 25 is a reliable<br />
and valid instrument to measure vision-related quality <strong>of</strong> life in<br />
patients with visual impairment hence can be applied to clinical<br />
research.<br />
Key Words: NEI VFQ-25, psychometric analysis, quality <strong>of</strong> life,<br />
questionnaire<br />
4:54 pm – 5:01 pm<br />
FP-5<br />
Efficacy <strong>of</strong> Dry Heat Utilizing a Commercial Oven Toaster in<br />
the Sterilization <strong>of</strong> Stainless Steel Discs<br />
Maria Cielo R. Dizon, Robert Christian F. Reyes<br />
Objective: To determine the efficacy <strong>of</strong> dry heat utilizing a<br />
commercial oven toaster in the sterilization <strong>of</strong> stainless steel discs<br />
in comparison to steam sterilization using the autoclave.<br />
11<br />
Methods: This was an experimental study utilizing a total <strong>of</strong> 198<br />
stainless steel discs, representative <strong>of</strong> stainless steel ophthalmic<br />
instruments, that were equally divided into 9 sets. They were<br />
sterilized by autoclave then inoculated with Staphylococcus<br />
aureus, Pseudomonas aeruginosa and Bacillus subtilis. The<br />
inoculated discs were wrapped again in sets and divided equally<br />
into 3 groups. The sets assigned to Group A underwent steam<br />
sterilization using an autoclave set at 121 C at 15 psi for 15<br />
minutes. The sets assigned to Groups B and C underwent dry heat<br />
sterilization using a commercial oven toaster at a temperature <strong>of</strong><br />
190 C for 15 minutes and 200 C for 15 minutes, respectively.<br />
After the sterilization process, the stainless steel discs were<br />
submerged in tryptic soy broth (TSB). One loopful <strong>of</strong> the TSB was<br />
streaked unto blood agar plates. The plates were incubated at<br />
37 C and checked for bacterial growth (positive or negative) after<br />
24 hours and 48 hours. Fisher’s Exact Test and Chi Square Test<br />
were used to analyze the data obtained.<br />
Results: After 48 hours <strong>of</strong> incubation, there was no growth<br />
observed on all the plates in the autoclave group (Group A). In<br />
Group B (oven toaster 190 C for 15 minutes), there was no growth<br />
in all the plates <strong>of</strong> Pseudomonas aeruginosa and Bacillus subtilis.<br />
For Staphylococcus aureus, positive growth was seen in 1 out <strong>of</strong><br />
20 plates. Statistical analysis using both the Chi Square Test and<br />
Fisher’s Exact Test showed that the growth <strong>of</strong> Staphylococcus<br />
aureus in the oven toaster group was not statistically significant.<br />
In Group C (oven toaster 200 C for 15 minutes), there was no<br />
growth observed in all the plates.<br />
Conclusion: The oven toaster set at 190 C for 15 minutes was<br />
100% effective in the sterilization <strong>of</strong> discs inoculated with P.<br />
aeruginosa and B. subtilis and the oven toaster set at 200 C for 15<br />
minutes was 100% effective in the sterilization <strong>of</strong> discs inoculated<br />
with S. aureus. In the sterilization <strong>of</strong> stainless steel discs, the<br />
oven toaster is non-inferior to the autoclave (all p > 0.05). The<br />
oven toaster may be considered in the sterilization <strong>of</strong> stainless<br />
steel ophthalmic instruments, especially when an autoclave is not<br />
available.<br />
Key Words: sterilization, oven toaster, dry heat<br />
FREE PAPER SESSION 1<br />
<strong>Meeting</strong> Room 4-6<br />
8:30 - 10:30 am<br />
Chair: Jennifer Bernabe-Ko, MD<br />
Co-Chair: Marichele Aventura-Isidro , MD<br />
External Disease and Cornea<br />
8:30 am - 8:37 am<br />
FP-6<br />
Dry Eye After Clear Cornea Phacoemulsification<br />
Peter Mark G. Chao, Ruben Lim Bon Siong<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines<br />
Objective: To determine the incidence <strong>of</strong> dry eye in patients after<br />
undergoing clear cornea phacoemulsification; and to investigate
the changes in dry eye symptoms and tear physiology before and<br />
after clear cornea phacoemulsification.<br />
Methods: Study design was single-center, non-randomized,<br />
longitudinal, and prospective. The study involved forty four<br />
patients (49 eyes), diagnosed with age-related cataract, who<br />
underwent corneal phacoemulsification. Subjective grading<br />
<strong>of</strong> ocular discomfort, ocular surface disease index (OSDI),<br />
fluorescein tear break-up time (FTBUT), corneal staining,<br />
conjunctival and posterior lid margin staining with lissamine<br />
green, and Schirmer test without anesthesia and with anesthesia<br />
were assessed before surgery and 1 week, 1 month, and 3<br />
months after the surgery.<br />
Results: None <strong>of</strong> the patients enrolled qualified for the<br />
definition <strong>of</strong> dry eye disease before and after clear cornea<br />
phacoemulsification. Pre-operative FTBUT (14.01 seconds ±<br />
0.56) significantly decreased 1 week after surgery (3.97 seconds<br />
± 0.21; p
were determined using Sensititre Microtitre Colorimery method<br />
following guidelines <strong>of</strong> the Clinical and Laboratory Standards<br />
Institute for broth microdilution testing <strong>of</strong> yeasts and filamentous<br />
fungi. Two-way ANOVA, Duncan Test, and Pearson Chi Square<br />
test were used to analyze the data.<br />
Results: All isolates tested were sensitive to Voriconazole. Eighty<br />
percent <strong>of</strong> the isolates were sensitive to Amphotericin B. Twenty<br />
five percent showed resistance to Itraconazole. Yeast pathogens<br />
were all sensitive to Amphotericn B and Voriconazole. More than<br />
50% <strong>of</strong> the yeast pathogens were resistant to Ketoconazole.<br />
Molds or filamentous fungi showed higher susceptibility to<br />
Voriconazole than Amphotericin B and the other antifungals. All<br />
<strong>of</strong> the isolates were sensitive to Voriconazole followed by 66% <strong>of</strong><br />
the isolates being sensitive to Amphotericin B.<br />
Conclusion: Voriconazole exhibited good in vitro activity<br />
against the isolates tested on. It has the same efficacy on Yeast<br />
pathogens as compared with the gold standard, Amphotericn B.<br />
It has superior efficacy on Filamentous fungi. There is a role for<br />
Voriconazole in the treatment <strong>of</strong> Ocular infections especially in<br />
the setting <strong>of</strong> poor antifungal drug availability.<br />
Key Words: Amphotericin B, Voriconazole, AntifungalVoriconazole<br />
8:54 am - 9:01 am<br />
FP-9<br />
No Glue, No Suture Technique? Of Pterygium Surgery:<br />
A Local Experience<br />
Ma. Melizza Theresa T. Ramirez¹, Emerson M. Cruz², Evelyn S.<br />
Morabe¹, Roland B. Bagnes, II¹, Jan Michael R. Reyes¹<br />
¹Jose R. Reyes Memorial Medical Center, Philippines, ²Asian Eye<br />
Institute, Philippines<br />
This is to report our initial experience with the "No glue, No<br />
suture?" technique <strong>of</strong> pterygium surgery by Dr. Santanu Mitra <strong>of</strong><br />
India.<br />
Objective: The objective is to determine if autologous blood<br />
is indeed effective in securing the conjunctival autograft to the<br />
scleral bed after excision <strong>of</strong> pterygium.<br />
Methods: This is a case series <strong>of</strong> 15 patients with primary<br />
pterygium seen at JRRMMC from April to July <strong>2012</strong>. The surgery<br />
was done following the technique described by Mitra S. et al.,<br />
which was presented at the AAO <strong>Annual</strong> <strong>Meeting</strong> in Florida last<br />
Oct. 2011. The technique involved the use <strong>of</strong> autologous blood<br />
to secure fixation <strong>of</strong> the conjunctival autograft to the scleral bed<br />
following pterygium excision. "Success" is defined as adherent<br />
conjunctival autograft at the end <strong>of</strong> 1 month observation period.<br />
Results: Eight males and 7 females, age ranging from 24 to 76<br />
years (mean <strong>of</strong> 49.9 + 13.4) were included. The most common<br />
indication for surgery was pterygium > 3mm and persistent foreign<br />
body sensation. All surgeries were completed uneventfully, with<br />
graft size ranging from 60 to 96 mm2. Conjunctival autologous<br />
grafting was successful in 12 <strong>of</strong> 15 cases (80%). Complications<br />
were graft loss in 3 patients (20%) and graft contraction in 2 other<br />
patients. (13%).<br />
13<br />
Oral Free Papers<br />
Conclusion: Autologous blood was effective in producing<br />
conjunctival autograft adherence, with successs rate <strong>of</strong> 80%. We<br />
recommend a randomized controlled trial with larger sample size<br />
to compare the results, including recurrence rates, with sutured<br />
and glued grafts.<br />
Key Words: no suture<br />
9:11 am - 9:18 am<br />
FP-10<br />
A Randomized Controlled Trial <strong>of</strong><br />
Tobramycin-Dexamethasone, Tobramycin, and Nepafenac<br />
Eye Drops in Patients with Acute Follicular Conjunctivitis<br />
Melquiades D. Figueroa<br />
Jose R. Reyes Memorial Medical Center, Philippines<br />
Objective: To compare the efficacy <strong>of</strong> topical Tobramycin-<br />
Dexamethasone, Tobramycin, and Nepafenac eyedrops,<br />
in relieving patient’s discomfort and conjunctival hyperemia<br />
associated with acute follicular conjunctivitis <strong>of</strong> presumed viral<br />
etiology.<br />
Methods: Patients presenting with acute follicular conjunctivitis,<br />
presumed viral in origin, were grouped using a simple random<br />
sampling. Conjunctival hyperemia was then assessed using<br />
Likert-type scales: 0-no hyperemia; 1-mild; 2-moderate; and<br />
3-severe. The first group was given Tobramycin-Dexamethasone<br />
eyedrops four times daily; Second group with Tobramycin alone<br />
four times daily; and the last group with Nepafenac eye drops<br />
thrice a day for 1 week. Patients were then requested to have<br />
a follow-up after 5-6 days <strong>of</strong> treatment. They were asked to<br />
complete a questionnaire on whether they thought the treatment<br />
had helped alleviate the discomfort.<br />
Results: A total <strong>of</strong> 42 patients were randomized into 3 groups<br />
equally: Fourteen (14) received Tobramycin-Dexamethasone;<br />
14 Tobramycin alone; and 14 received Nepafenac drops. Most<br />
patients (61%) sought consult within the first 3 days <strong>of</strong> manifesting<br />
symptoms. 28 patients (75%) presented without lymphadenopathy,<br />
and 57% had bilateral findings. Using Fischer’s method, it was<br />
found out that there was no significant difference among the 3<br />
groups in terms <strong>of</strong> mean conjunctival hyperemia (p=0.05). Most<br />
patients in all 3 groups reported symptomatic improvement<br />
with treatment. Patients on Tobramycin-Dexamethasone drops<br />
reported symptomatic relief such as reduced tearing (86%), and<br />
pain less than 3 days <strong>of</strong> instillation (93%). No patient on the said<br />
treatment experienced any serious complication. Two patients<br />
(14%) on Tobramycin drops alone developed pseudomembrane<br />
while 2 patients (14%) on Nepafenac drops developed punctate<br />
epithelial keratitis and subepithelial infiltrates. There was a<br />
significant difference between Tobramycin-Dexamethasone and<br />
Tobramycin in the improvement <strong>of</strong> tearing (p=0.01). However,<br />
there was no significant difference (p=0.01) on patient’s<br />
improvement particularly on conjunctival blurring and pain<br />
with Tobramyin-Dexamethasone, Tobramycin nor Nepafenac<br />
eyedrops.<br />
Conclusion: Based on physician’s grading <strong>of</strong> conjunctival<br />
hyperemia before and after follow-up no significant difference
was found among the three treatments. However, more<br />
patients favorably respond to Tobramycin - Dexamethasone in<br />
improvement <strong>of</strong> tearing, and no complication was recorded after<br />
the short-course <strong>of</strong> treatment.<br />
9:19 am - 9:26 am<br />
FP-11<br />
Retrospective Study Comparing Femtosecond Lenticule<br />
Extraction (FLEX) with Femtosecond Laser In-Situ<br />
Keratomileusis For Myopia<br />
Tina Marie Saban-Roa, Irwin Y. Cua, Ruben Lim Bon Siong<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
Objective: To compare the efficacy, safety, predictability, stability,<br />
contrast sensitivity and higher-order aberration <strong>of</strong> patients who<br />
underwent Femtosecond lenticule extraction (FLEX) and patients<br />
who underwent Femtosecond Laser In-Situ Keratomeliuesis<br />
(Femto-LASIK).<br />
Methods: Retrospective review <strong>of</strong> FLEx and Femto-LASIK cases<br />
in the International Eye Institute, St. Luke’s Medical Center,<br />
Global City from November 2011 to May <strong>2012</strong> was done.<br />
Results: 26 eyes <strong>of</strong> 13 patients who underwent FLEx while 22<br />
eyes <strong>of</strong> 11 patients who underwent Femto-LASIK were included.<br />
The spherical equivalent <strong>of</strong> the FLEx group ranged from -2.50 to<br />
-6.75 and the Femto-LASIK group ranged from -2.63 to -6.875.<br />
Eyes which achieved uncorrected visual acuity (UCVA) <strong>of</strong> 20/32<br />
or better 1 day post-operatively was 15% and 100% for the FLEx<br />
and Femto-LASIK groups, respectively, but were similar after 3<br />
months. Spherical equivalent after 3 months was +0.06(±0.21)<br />
in the FLEx group and -0.44 (±0.35) in the Femto-LASIK group,<br />
which was statistically significant (p
is the first documented case <strong>of</strong> intraepithelial infiltrates within<br />
the flap <strong>of</strong> 1 eye after uneventful bilateral femtosecond LASIK<br />
concurrent with an acute dermatologic episode <strong>of</strong> psoriasis.<br />
There were no final adverse effects.<br />
Key Words: Psoriasis, keratitis, Laser in situ keratomileusis<br />
Optics, Refraction, and Contact Lens<br />
9:43 am - 9:50 am<br />
FP-14<br />
The Anti-microbial Efficacy <strong>of</strong> Multipurpose Contact Lens<br />
Solutions on Standard Strains <strong>of</strong> Common Ocular Pathogens<br />
Eleonore B. Iguban, Juan Pablo R. Nanagas,<br />
Roslyn F. De Mesa- Rodriguez<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines<br />
Objective: This study aims to compare the anti-microbial<br />
efficacy <strong>of</strong> locally available multi-purpose contact lens solutions<br />
on standard strains <strong>of</strong> contact lens-related ocular pathogens. It<br />
also seeks to establish the recommended duration <strong>of</strong> exposure to<br />
multi-purpose contact lens solutions in order to achieve maximal<br />
anti-microbial effect.<br />
Methods: This study, a single-blind controlled experiment,<br />
evaluated five locally available multi-purpose solutions in terms<br />
<strong>of</strong> their anti-microbial efficacy towards common contact lensrelated<br />
ocular pathogens, namely Pseudomonas aeroginosa,<br />
Staphylococcus aureus, Eschericha coli, Fusarium solani and<br />
Candida albicans, using the stand alone criteria for determination<br />
<strong>of</strong> contact lens disinfection efficacy. Microbial viability counts were<br />
then obtained at serial durations namely after 1 hour, 3 hours, 6<br />
hours, and 12 hours <strong>of</strong> exposure.<br />
Results: Results <strong>of</strong> this study showed that the multi-purpose<br />
contact lens solutions containing Polyquaternium-1 and<br />
Myristamidopropyl dimethylamine (MPS C) and polyhexanide<br />
(MPS B and D) were able to reduce the bacterial concentrations<br />
by 3 log and fungal concentrations by 1 log, thus enabling them<br />
to fulfill the stand-alone criteria for disinfecting solutions as<br />
mandated by ISO/CD 14729. This anti-microbial efficacy was<br />
most evident at 6 hours <strong>of</strong> exposure <strong>of</strong> challenge organisms<br />
to the multi-purpose contact lens solutions. Moreover, the<br />
multipurpose contact lens solution containing Polyquaternium-1<br />
and Myristamidopropyl dimethylamine, was found to be have the<br />
broadest spectrum <strong>of</strong> effectivity against gram negative and gram<br />
positive bacteria, as well as Candida albicans. All multipurpose<br />
contact lens solutions tested in this study were found to have poor<br />
microbial activity against Fusarium solani, which is known for its<br />
high virulence and pathogenicity.<br />
Conclusions: Multi-purpose contact lens solutions truly show<br />
a wide range <strong>of</strong> variability in terms <strong>of</strong> their antimicrobial activity.<br />
A contact lens solution that has a better and broad spectrum<br />
antimicrobial efficacy compared to its counterparts in the local<br />
market could provide higher chance <strong>of</strong> attaining ocular safety<br />
among non-compliant contact lens users. Greater efforts to<br />
educate patients on proper lens care regimens are needed to<br />
15<br />
Oral Free Papers<br />
prevent contact lens- related microbial keratitis from common<br />
ocular pathogens.<br />
Key Words: contact lens, infectious keratitis, microbial keratitis,<br />
multipurpose contact lens solution, silicon hydrogels<br />
Chair: Raoul Paolo D. Henson, MD<br />
Co-Chair: Ma. Perla E. Duran, MD<br />
Orbit, Eyelids, Lacrimal, and Plastic<br />
10:01 - 10:08 am<br />
FP-15<br />
Superior Orbital Fissure Syndrome in Herpes<br />
Zoster Ophthalmicus<br />
Joanna Camille See Co, Ritsia A. Wastitiamurti<br />
Fatima University Medical Center, Philippines<br />
Case Summary: A 55 y.o male was admitted for herpes<br />
zoster ophthalmicus (HZO) with complaints <strong>of</strong> periorbital pain,<br />
swelling <strong>of</strong> the left eye, and cutaneous vesicular lesions on<br />
the left forehead and eyelid. Initially, conjunctivalchemosis and<br />
epithelial keratitis were noted. Oral and ophthalmic antiviral<br />
and anti-inflammatory therapies were started. 1 week after,<br />
patient developed ptosis, diplopia, anisocoria, and partial<br />
ophthalmoplegia which became complete after 7 days. Superior<br />
orbital fissure syndrome (SOFS) was considered and CT-scan<br />
and MRI were requested. Methylprednisolone p.o. in tapering<br />
dosage for 2 weeks was given. 8 weeks after, Patient responded<br />
well with the treatment and improvement in the anterior segment<br />
symptoms, ophthalmoplegia, and ptosis, but not anisocoria were<br />
noted. SOFS is characterized by ophthalmoplegia, ptosis, fixed<br />
dilated pupils, and anesthesia <strong>of</strong> cranial nerve V1. It is associated<br />
with presence <strong>of</strong> traumatic injuries, tumours <strong>of</strong> the orbit, infection,<br />
inflammatory disorders, and vasculitic diseases. It is a relatively<br />
uncommon complication in patients who suffers from HZO. It<br />
can start as a simple reactivation <strong>of</strong> the virus to a more severe<br />
complication affecting structures located in the apex and fissures.<br />
A delay in identifying and management can lead to devastating<br />
sequelae such as chronic ocular inflammation, ophthalmoplegia,<br />
and visual loss.<br />
Key Words: Herpes zoster ophthalmicus, Superior Orbital<br />
Fissure Syndrome, ophthalmoplegia, anisocoria<br />
10:09 - 10:16 am<br />
FP-16<br />
Exophthalmometric Values <strong>of</strong> Adult Filipinos in a Rural Area:<br />
Barangay Bigaa, Cabuyao, Laguna<br />
Roland B. Bagnes, II, Evelyn S. Morabe, Anthony Christopher G.<br />
Ortiz, Ma. Melizza Theresa T. Ramirez, Jan Michael R. Reyes<br />
Jose R. Reyes Memorial Medical Center, Philippines<br />
Objectives: Our aim is to determine the normal exophthalmometry<br />
values among Filipinos (18-60 years old) living in a rural Philippine<br />
village, and correlate results with demographic, physical and<br />
ocular factors.
Methods: In this cross-sectional study, randomly selected<br />
adult participants from Baraangay Bigaa, Cabuyao Laguna<br />
were examined by residents from the JRRMMC Department<br />
<strong>of</strong> Ophthalmology. Exophthalmometry was performed using<br />
a Hertel’s exophthalmometer (Oculus 35582 Germany). The<br />
exophthalmometry reading to the closest 0.5mm was taken<br />
simultaneously for both eyes and the base recorded to the<br />
nearest 1.0mm. Automated refraction was done using Huvitz<br />
(HRK7000), and axial length was measured using a s<strong>of</strong>t-touch<br />
A-Scan (Accutome USA). Height (cm) and weight (kg) were<br />
measured and BMI computed as kg/m2. Results were analysed<br />
using Minitab Ver16 statistical s<strong>of</strong>tware.<br />
Results: Total <strong>of</strong> 173 subjects participated and 3 patients<br />
were excluded, leaving 170 patients for analysis (104<br />
females & 66 males) with mean age <strong>of</strong> 46.4 years. The mean<br />
exophthalmometric value obtained was 13.8+/- 2.1mm. Females<br />
had significantly lower mean values at 13.5mm +/- 2.0 compared<br />
to 14.2mm+/- 2.2 for males. The relative ocular protrusion value<br />
in our subjects was 2 mm. Gender, BMI, axial length, weight and<br />
base were significantly associated with exophthalmometry values<br />
on bivariate analysis. However, on multivariate analysis, weight<br />
and base measurements were shown to be the only independent<br />
factors affecting the exophthalmometry values.<br />
Conclusion: Exophthalmometry values obtained among Filipino<br />
adults living in Brgy. Bigaa, Cabuyao, Laguna were lower than the<br />
reported values for other population. It is hoped that the values we<br />
obtained will henceforth be a helpful reference value in determing<br />
the presence or absence <strong>of</strong> absolute exophthalmos in Filipino<br />
patients being evaluated for the presence <strong>of</strong> orbital disease.<br />
Key Words: Exophthalmometer, Population, Axial Length, Mean<br />
Exophthalmometric Value, Relative Ocular Protrusion Value,<br />
Base, Exophthalmometry<br />
10:17 - 10:24 am<br />
FP-17<br />
Preseptal Cellulitis, Orbital Cellulitis and Cavernous Sinus<br />
Thrombosis in Jose R. Reyes Memorial Medical Center<br />
Anne Marfe L. Tan, Anthony Christopher G. Ortiz,<br />
Evelyn S. Morabe, Roland B. Bagnes, II<br />
Jose R. Reyes Memorial Medical Center, Philippines<br />
Objectives: To determine the clinical patterns <strong>of</strong> Preseptal<br />
Cellulitis, Orbital Cellulitis and Cavernous Sinus Thrombosis in a<br />
tertiary government hospital in terms <strong>of</strong> patient pr<strong>of</strong>ile, organisms<br />
involved, and antibiotic sensitivity patterns.<br />
Methods: Patients diagnosed with Preseptal Cellulitis, Orbital<br />
Cellulitis and Cavernous Sinus Thrombosis seen at Jose R. Reyes<br />
Memorial Medical Center from February 2011-August <strong>2012</strong>, with<br />
available Culture and Sensitivity results were included in this case<br />
series. Gram stain, Culture and Sensitivity studies were done<br />
on eye discharge and/ or abscess drainage. All patients with<br />
impression <strong>of</strong> Orbital Cellulitis underwent Cranial CT Scan with<br />
Orbital cuts. Blood Culture and Sensitivity was also requested for<br />
patients suspected to have Cavernous Sinus Thrombosis.<br />
Results: A total <strong>of</strong> 112 patients participated in this study with<br />
an age range <strong>of</strong> 1-75. Mean age at presentation was 26.31.<br />
There were 68 females and 44 males, with female to male<br />
ratio <strong>of</strong> (1.5:1). 98 patients had Preseptal cellulitis, 14 patients<br />
had Orbital cellulitis. In 8 <strong>of</strong> these 14 patients, Cavernous Sinus<br />
Thrombosis was diagnosed by neuroimaging studies. Only<br />
22.32% <strong>of</strong> cultures yielded positive results but the most common<br />
isolate in all 3 conditions was Staphyloccocus Aureus. Sensitivity<br />
tests <strong>of</strong> Staphyloccocus Aureus isolates showed 100% sensitivity<br />
to Chloramphenicol, Cotrimoxazole, Gentamicin, Tetracycline<br />
and 100% resistant to Oxacillin and Penicillin. All patients with<br />
Preseptal Cellulitis and Orbital Cellulitis resolved with no serious<br />
complication. Three patients diagnosed with Cavernous Sinus<br />
Thrombosis expired while 5 other patients recovered with no<br />
serious complication. Conclusion: Preseptal cellulitis should be<br />
distinguished early from Orbital cellulitis, an extremely serious<br />
infection that can spread posteriorly to the cavernous sinus. CT<br />
scan and Microbial studies aid in the diagnosis and treatment.<br />
Pending availability <strong>of</strong> laboratory results, the sensitivity patterns<br />
noted in this study can be used as a guide.<br />
Key Words: Cellulitis, Preseptal, Orbital, Cavernous Sinus<br />
Thrombosis<br />
Pathology and Intraocular Tumors<br />
10:25 am - 10:32 am<br />
FP-18<br />
Your Common Sore Eyes or Something Endemic?<br />
Charl Marlo A. Jimenez<br />
DOH Eye Center East Avenue Medical Center, Philippines<br />
Objective: To document and report a rare case <strong>of</strong> an 18 year old<br />
female presenting throughout the course <strong>of</strong> illness sore eyes and<br />
eventually transforming into a conjunctival mass.<br />
Methods: Case Report Method<br />
Oral Free Papers<br />
Results: A case <strong>of</strong> an 18 year old female who initially came in<br />
complaining <strong>of</strong> intermittent eye redness, itchiness and tearing<br />
for the past 3-6 months. She would claim <strong>of</strong> usage <strong>of</strong> brazen<br />
<strong>of</strong> antibiotics and combinations recommended by both general<br />
physicians and ophthalmologists in their locale which would<br />
provide partial relief <strong>of</strong> symptoms. In lieu the aforementioned<br />
history, loss <strong>of</strong> vision, diplopia and dizziness would not be<br />
encountered by the patient. Although the persistence <strong>of</strong> the<br />
aformentioned symptoms and an increasingly obvious growth <strong>of</strong><br />
a conjunctival mass led to consult the DOH Eye Center. Patient<br />
was initially treated as ocular tuberculosis, work-up was done,<br />
in order to rule out other diagnoses such as ocular cicatricial<br />
pemphigoid and squamous cell carcinoma. When the patient was<br />
finally cleared for operation, excision biopsy <strong>of</strong> conjunctival mass<br />
was done with cryotherapy and amnion graft placement on the left<br />
conjunctiva under general anesthesia which she tolerated well.<br />
Conclusion: The specimens were sent <strong>of</strong> histopathology and<br />
Immun<strong>of</strong>luorescence studies - which recorded negative for<br />
fibrinogen, C1g, C3c, IgM and IgA. It showed chronic inflammation<br />
whereas lymphoproliferative diseases cannot be ruled out. The<br />
bulbar mass, measuring 2 x 2 x 2 mm and marginal sections<br />
16
also sent for histopathology, revealed chronic granulomatous<br />
inflammation highly suggestive <strong>of</strong> conjunctival tuberculosis.<br />
Patient was then referred for TB treatment and subsequent<br />
follow-up was done.<br />
Key Words: conjunctival TB, ocular cicatricial pemphigoid,<br />
papilloma, ocular TB, squamous cell, carcinoma<br />
FREE PAPER SESSION 2<br />
<strong>Meeting</strong> Rooms 4-6<br />
9:05 - 11:30 am<br />
Retina and Vitreous<br />
9:05 - 9:12 am<br />
FP-19<br />
Macular Measurements and Best Corrected Visual Acuity<br />
after Phacoemulsification in Diabetics with and without Partial<br />
Posterior Vitreous Detachment/ Focal Macular Traction<br />
Katrina Charisse T. Magno, Milagros H. Arroyo<br />
University <strong>of</strong> the Philippines-Philippine General Hospital<br />
Philippines<br />
Objective: To document the presence or absence <strong>of</strong><br />
pre-phacoemulsifcation Partial Posterior Vitreous Detachment<br />
(PPVD)/ Focal Macular Traction (FMT) and to compare the<br />
post-phaco changes in macular thickness using Optical<br />
Coherence Tomography (OCT)-derived macular measurements<br />
<strong>of</strong> Central Macular Thickness (CMT) and Total Macular Volume<br />
(TMV), and post-phaco Best-Corrected Visual Acuity (BCVA) in<br />
patients with Non-Proliferative Diabetic Retinopathy (NPDR) at<br />
the Department <strong>of</strong> Ophthalmology and Visual Sciences, Philippine<br />
General Hospital, from the period <strong>of</strong> January-June <strong>2012</strong>.<br />
Methods: 10 adult diabetics with Non-Proliferative Diabetic<br />
Retinopathy and who were scheduled for Phacoemulsification<br />
were included in the study. All pre-phaco eyes underwent OCT<br />
examination using OCT Stratus Zeiss with s<strong>of</strong>tware version 4.0<br />
to document presence / absence <strong>of</strong> Partial Posterior Vitreous<br />
Detachment (PPVD)/Focal Macular Traction (FMT). Two<br />
quantitative OCT measurements: Central Macular Thickness<br />
(CMT) and Total Macular Volume (TMV) were measured<br />
automatically using OCT retinal mapping s<strong>of</strong>tware. OCT was<br />
repeated at 6 weeks post-surgery. Main outcome measures are as<br />
follows: OCT assessment <strong>of</strong> the pre-phacoemulsification presence<br />
or absence <strong>of</strong> Partial Posterior Vitreous Detachment (PPVD)/Focal<br />
Macular Traction (FMT) OCT-derived macular measurements,<br />
Central Macular thickness (CMT) and Total Macular Volume<br />
(TMV) obtained at one week pre-Phacoemulsification and at 6<br />
weeks post-Phaco\n? Best Corrected Visual Acuity (BCVA) with<br />
the EDTRS chart in logmar units obtained 1 week pre-phaco, and<br />
at Day 1, Week 1, 2 and 6 post-phaco.<br />
Results: 10 eyes with NPDR were included in the study.<br />
6/10 eyes had PPVD/FMT pre-phacoemulsification. After<br />
Phacoemulsification, CMT in eyes without PPVD/FMT was<br />
statistically insignificant at p=0.20. CMT in eyes with PPVD/FMT<br />
17<br />
Oral Free Papers<br />
was statistically insignificant at p=0.65. Mean post-phaco CMT<br />
between groups was not statistically significant at p=0.33. TMV in<br />
eyes without PPVD/FMT was statistically insignificant at p=0.56.<br />
TMV in eyes with PPVD/FMT was statistically insignificant at<br />
p=0.28. Mean post-phaco TMV between groups was statistically<br />
insignificant at p=0.26. BCVA improved at day 1 post-phaco in<br />
both groups and showed no deterioration till the 6th week postphaco<br />
despite the increasing macular measurements. Differences<br />
between groups however were not statistically significant at day 1<br />
post-op (p=0.26), week 1 (p=0.32), week 2 (p=0.88) and at week<br />
6 (p=0.83).<br />
Conclusion: In this study, eyes with or without PPVD/FMT were<br />
observed to have an insignificant increase in macular thickness<br />
and volume after phacoemulsification. Insignificant improvement<br />
in BCVA continued till the 6 weeks post-phacoemulsification<br />
despite an increased CMT and TMV in both groups. A larger<br />
subject pool, a longer follow-up period as well as use <strong>of</strong> an<br />
upgraded OCT are recommended for future studies.<br />
Key Words: Optical Coherence Tomography, Diabetic<br />
Retinopathy<br />
Uveitis and Intraocular Inflammation<br />
9:13 - 9:20 am<br />
FP-20<br />
Full Field Electroretinography in Type 2 Diabetes Mellitus<br />
with No Diabetic Retinopathy and Mild Diabetic Retinopathy<br />
Institution: St. Luke’s Medical Center<br />
Rachelle G. Anzures, Leslie Gatchalian<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
Objective: To describe and compare the full field<br />
electroretinograph <strong>of</strong> type 2 diabetes mellitus patients with no<br />
diabetic retinopathy and mild diabetic retinopathy. To correlate<br />
the electroretinographic changes noted with HbA1c, duration <strong>of</strong><br />
diabetes, age, gender, BMI, type <strong>of</strong> medication and smoking.<br />
Methods: The subject population was composed <strong>of</strong> 18 eyes <strong>of</strong> 10<br />
patients with type 2 diabetes mellitus. They were recruited from<br />
St. Luke’s Medical Center out patient department and private<br />
clinics from October 2011 to June <strong>2012</strong>. Medical history taking<br />
and comprehensive ophthalmic examination was done on each<br />
patient. The patients who met the inclusion criteria proceeded with<br />
HbA1c, fluorescein angiography and full field electroretinography.<br />
Independent masked retina specialist and neurophysiologist<br />
interpreted the respective results.<br />
Results/Conclusion: Prolonged oscillatory potential 1 implicit<br />
time is the most common ERG abnormality seen in patients with<br />
Type 2 DM patients with no diabetic retinopathy and mild diabetic<br />
retinopathy regardless <strong>of</strong> HbA1c level and disease duration.<br />
Higher percentage <strong>of</strong> patients with delayed OP1 implicit time<br />
is seen in patients with mild diabetic retinopathy compared to<br />
patients with no diabetic retinopathy. Disturbances <strong>of</strong> the ERG
components is more consistent in patients with disease duration<br />
<strong>of</strong> 5 years and more, male gender, smoking and age 51 years<br />
and above.<br />
Key Words: Full Field Electroretinography, Mild Diabetic<br />
Retinopathy, Type 2 Diabetes Mellitus, No Diabetic Retinopathy<br />
9:21 - 9:28 am<br />
FP-21<br />
Measurement <strong>of</strong> Retinal Nerve Fiber Thickness in Patients<br />
with Diabetic Retinopathy<br />
Maria Cecilia Arenal, Romulo Aguilar<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
Objective: The study was carried out to detect whether there<br />
is early neuronal degeneration or atrophy among patients with<br />
diabetes using the Cirrus SD-OCT.<br />
Methods: 26 diabetic subjects (52 eyes) with varying degrees<br />
<strong>of</strong> diabetic retinopathy and 24 age-matched controls (48 eyes)<br />
without optic nerve and retinal disease were analyzed. RNFL<br />
thickness around the disc was measured using Cirrus, SD-OCT.<br />
Results: The average RNFL thickness was found to be<br />
significantly thinner among diabetics (95 +/-10um) compared<br />
to control (99.2+/-9.8um; p=0.04). Comparing all quadrants,<br />
only the temporal RNFL thickness was noted be significantly<br />
different between the 2 groups (66.5+/-9.6 um versus 73.6+/-<br />
13.6 um; p=0.003). RNFL thickness did not seem exhibit a linear<br />
relationship with either Hba1c or duration <strong>of</strong> diabetes.<br />
Conclusion: Measurement <strong>of</strong> RNFL thickness <strong>of</strong>fers another<br />
non-invasive and affordable and screening tool for diabetic<br />
retinopathy. Evidence <strong>of</strong> neuronal degeneration or atrophy found<br />
in this study may pave the way for the development <strong>of</strong> a new<br />
therapeutic strategies for Dr. like neuroprotection.<br />
Key Words: diabetic retinopathy, retinal nerve fiber layer<br />
thickness, Cirrus SD-OCT, HBALC<br />
9:29 - 9:36 am<br />
FP-22<br />
Macular Pigment Optical Density <strong>of</strong> Healthy Eyes in<br />
University <strong>of</strong> Santo Tomas Hospital<br />
Ernesto D. Pablo, Jr.<br />
University <strong>of</strong> Sto. Tomas Hospital, Philippines<br />
Objective: To determine the Macular Pigment Optical Density<br />
(MPOD) <strong>of</strong> healthy eyes in the University <strong>of</strong> Santo Tomas<br />
Hospital using a macular pigment densitometer (Macuscope). To<br />
determine significant difference between Age and Sex with the<br />
MPOD values.<br />
Methods: Cross sectional, prospective study <strong>of</strong> 60 healthy eyes<br />
in the University <strong>of</strong> Santo Tomas Hospital from June <strong>2012</strong>-August<br />
<strong>2012</strong>. The subjects underwent complete ophthalmologic exam to<br />
satisfy the requirements for the inclusion and exclusion criteria.<br />
The subjects had MPOD measurement with a macular pigment<br />
densitometer.<br />
Results: The mean MPOD in the sample population was<br />
0.275±0.025 log units (0.25-0.30) using the MAD t test. There<br />
were no significant difference between MPOD values with age<br />
(p>0.15) and sex (p>0.99).<br />
Conclusion: The study establishes MPOD levels in the given<br />
population. Age and sex do not affect the MPOD levels.<br />
Key Words: Macular pigment optical density, Macular pigments,<br />
heterochromatic flicker, photometry, Lutein, mesozeaxanthin,<br />
zeaxanthin<br />
FP-23<br />
9:37 - 9:44 am<br />
Oral Free Papers<br />
Surgical benefits <strong>of</strong> Endo-Illumination Filters on the Stellaris<br />
PC Surgical System<br />
Alex U. Pisig, Emerson Molina, Margarita Justine O. Bondoc,<br />
Narciso F. Atienza, Jr.<br />
Cardinal Santos Medical Center, Philippines<br />
Endo-illumination is an indispensable tool for visualization<br />
<strong>of</strong> ocular tissues during vitreoretinal surgery. It is, however,<br />
important to balance between the need for bright illumination<br />
and protection from light hazard brought about by the illumination<br />
itself. The Stellaris PCä is integrated with different light sources<br />
<strong>of</strong>fering adjustments for different vitreoretinal surgery modalities<br />
without sacrificing optimal illumination and safety measures.<br />
Objective: To elucidate the surgical benefits <strong>of</strong> each <strong>of</strong> the color<br />
filters integrated in the Stellaris PC’s surgical system.<br />
Methods: Review <strong>of</strong> personal surgeon’s experience.<br />
Results: We describe our experiences with 78 eyes using the<br />
different illumination filters <strong>of</strong> Stellaris PCä surgical system, which<br />
is equipped with a dual bright light source (xenon and mercury<br />
vapor) and 3 color filters. The parameters used were 5000 cuts<br />
per minute (cpm) with vacuum <strong>of</strong> 300 mm Hg and the light source<br />
at 40% illumination. The xenon light source with the yellow or<br />
green filter was used for general core vitrectomy; the xenon<br />
light source with the green filter was used for macular work. The<br />
yellow filter provides good visualization and blocks blue light<br />
delivery to reduce phototoxicity and improve overall comfort.<br />
The green filter enhances contrast to help visualize structures<br />
and reduce dependency on indocyanine green angiography<br />
(ICG). The amber filter was used for diabetic cases with vitreous<br />
hemorrhage, tractional retinal detachment, and proliferative<br />
diabetic retinopathy. This filter passes the longest wavelengths<br />
and is potentially the safest for the unstained eye. The amber<br />
filter is excellent for peripheral vitreous procedures and minimizes<br />
glare from instruments during air/fluid exchange.<br />
Conclusion: The color filters available with the Stellaris PCä<br />
improve the surgeon’s ability to visualize ocular tissues under<br />
various surgical conditions, minimize phototoxicity, and optimize<br />
clinical outcomes. The Stellaris PCä system allows the surgeon<br />
to choose the light source and a color filter based on his or her<br />
needs.<br />
18
Oral Free Papers<br />
Key Words: Endo-illumination, Vitrectomy, Color Filters, Stellaris<br />
PC, Xenon light source, Mercury Vapor, Phototoxicity.<br />
9:45 am- 9:52 am<br />
FP-24<br />
Outcomes <strong>of</strong> Retinoblastoma Patients with High-risk<br />
Histopathological Features in a Tertiary Hospital<br />
Patricia E. Cabrera, Gary JV. Mercado,<br />
Rolando Enrique D. Domingo<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines<br />
Objective: To desribe the outcome <strong>of</strong> patients with bilateral or<br />
unilateral retinoblastoma with high-risk histopathological features<br />
managed at a tertiary hospital in the Philippines.<br />
Methods: This was a descriptive, retrospective review<br />
<strong>of</strong> retinoblastoma cases with high-risk histopathological<br />
characteristics seen at a tertiary hospital from January 1999 to<br />
July <strong>2012</strong>. Out <strong>of</strong> 239 patients, those with at least one <strong>of</strong> the<br />
following features were included in the study: positive cut optic<br />
nerve margin, post-laminar optic nerve involvement (PLONI),<br />
intra- or extrascleral involvement, choroidal invasion, and anterior<br />
segment involvement. We determined the number <strong>of</strong> patients who<br />
developed orbital recurrence and metastasis, otherwise known<br />
as events, within 1 year after enucleation or exenteration and<br />
compared the outcomes between those who received and did not<br />
receive adjuvant therapy.<br />
Results: Of the 82 eyes <strong>of</strong> 79 patients with high-risk<br />
histopathologic features, 25.6% had orbital recurrence and<br />
18.3% developed CNS, lymph node, or distant metastasis.<br />
None with isolated choroidal involvement (n=24) or combined<br />
choroidal and anterior segment involvement (n=4) developed<br />
recurrence or metastasis. Both patients with isolated anterior<br />
segment (n=1) and PLONI with negative margin involvement<br />
(n=1) remained event-free with chemotherapy. The following<br />
developed orbital recurrences: 2 <strong>of</strong> 9 patients with combined<br />
choroid and scleral involvement, and 1 <strong>of</strong> 8 patients with PLONI<br />
negative margin with choroidal involvement. These patients did<br />
not receive immediate post-operative chemotherapy. Two out <strong>of</strong><br />
4 patients with isolated PLONI with positive margin <strong>of</strong> resection<br />
developed metastasis despite adjuvant therapy. Of 12 patients<br />
with combined choroid, scleral, or anterior segment and PLONI<br />
with positive margin involvement, only 3 <strong>of</strong> the 7 patients who<br />
received full chemotherapy remained event-free, while the rest<br />
developed orbital recurrence or metastasis (9 <strong>of</strong> 12). Of 17<br />
patients with extrascleral involvement and varying degrees <strong>of</strong><br />
intraocular involvement and optic nerve margin involvement, only<br />
3 <strong>of</strong> the 9 who received full chemotherapy remained event-free,<br />
including two who received an intensive chemotherapy course.<br />
Conclusion: Our small sample size is attributable to limited<br />
patient follow-ups and chemotherapy drop-outs. Isolated choroidal<br />
and combined choroid and anterior segment involvement had no<br />
recurrences or metastasis either with or without adjuvant therapy.<br />
Patients with combined choroid and scleral involvement and<br />
those wih PLONI, negative margin with choroidal involvement<br />
had better outcomes with adjuvant therapy than without. Patients<br />
19<br />
with the following features developed events despite adjuvant<br />
therapy: positive optic nerve margin combined with any ocular<br />
tissue involvement, and extrascleral involvement combined with<br />
any other feature. We recommend giving a timely and complete<br />
chemotherapy regimen to prevent recurrence or metastasis in<br />
combined choroid and scleral involvement, and PLONI negative<br />
margin with choroidal involvement. We suggest intensive<br />
chemotherapy for patients with positive margin involvement or<br />
extrascleral involvement. Further studies are recommended<br />
to establish the need for chemotherapy in isolated PLONI and<br />
isolated anterior segment involvement.<br />
Key Words: Retinoblastoma, High-risk, Histopathology,<br />
Outcomes<br />
9:53 am - 10:00 am<br />
FP-25<br />
Choroidal Melanoma in a Patient with Nevus <strong>of</strong> Ota<br />
Bryan Jason B. Atienza<br />
The Medical City, Philippines<br />
Objective: To describe what we believe to be the first reported<br />
case <strong>of</strong> choroidal melanoma in a patient with Nevus <strong>of</strong> Ota in the<br />
Philippines.<br />
Methods: Case Report<br />
Results: This is a case <strong>of</strong> a 33 year-old Filipino male, presenting<br />
with unnoticed blurring <strong>of</strong> vision in right eye, detected on<br />
routine pre-employment physical exam. He was known to have<br />
congenital oculomucodermal melanocytosis, and was apparently<br />
well until present consult. Best corrected visual acuity was 20/30-<br />
2 in the right eye, and 20/20-1 in the left eye. Amsler grid showed<br />
metamorphopsia in superomedial quadrant <strong>of</strong> the right eye. Dilated<br />
eye exam showed an elevated choroidal mass approximately 10<br />
mm in diameter, immediately below the optic nerve, extending<br />
temporally involving the inferior aspect <strong>of</strong> the macula. B-scan<br />
revealed the peripapillary choroidal mass approximately 7.5 mm<br />
in thickness. MRI <strong>of</strong> the orbits were consistent with a melanincontaining<br />
tumor. Enucleation with scleral-wrapped orbital<br />
implant was done. Histopathology showed malignant melanoma,<br />
epithelioid type.<br />
Conclusion: Choroidal melanoma is the most common primary<br />
intraocular malignant tumor in adults. It is common in Caucasians,<br />
extremely rare in Blacks, with Hispanics and Asians having small<br />
to intermediate risk. Nevus <strong>of</strong> Ota, a hamartoma <strong>of</strong> dermal<br />
melanocytes, presents as a blue or gray patch on the face, and<br />
may involve ocular and oral mucosal surfaces. Less than 20<br />
cases worldwide since 1980 have been reported; we believe that<br />
this is the first reported case <strong>of</strong> choroidal melanoma presenting in<br />
a patient with oculomucodermal melanocytosis in the Philippines.<br />
It is important to recognize that choroidal melanoma may arise in<br />
patients diagnosed to have Nevus <strong>of</strong> Ota. Hence we recommend<br />
that fundus screening <strong>of</strong> these patients be performed.<br />
Key Words: choroidal, melanoma, nevus, ota, oculomucodermal,<br />
melanocytosis, malignant, tumor
Chair: Vicente Victor D. Ocampo, Jr., MD<br />
Co-chair: Ellen Yu-Keh, MD<br />
Uveitis and Intraocular Inflammation<br />
10:12 am - 10:19 am<br />
FP-26<br />
Choroidal Tuberculosis: A Case Report<br />
Johanna T. Cervantes, Juan S. Lopez<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
Objective: To describe a case report <strong>of</strong> choroidal tuberculosis in a<br />
44 year old male patient with no signs <strong>of</strong> pulmonary tuberculosis.<br />
Method: Case report<br />
Results: The patient presented with unilateral eye redness<br />
and blurring <strong>of</strong> vision. Fundoscopy revealed multiple yellow<br />
elevated nodules with ill-defined borders at the posterior pole and<br />
peripapillary area. T spot test was positive. Patient was started<br />
on anti-koch’s therapy with initial worsening <strong>of</strong> vision. Continued<br />
treatment provided gradual and steady improvement <strong>of</strong> signs and<br />
symptoms.<br />
Conclusion: Intraocular tuberculosis can occur without concurrent<br />
systemic tuberculosis. Patients may observe paradoxical initial<br />
worsening <strong>of</strong> lesions after initiation <strong>of</strong> treatment, but symptoms<br />
improve with continued medication.<br />
Key Words: Choroidal tuberculosis, T spot test, Intraocular TB,<br />
Tuberculoma, Jarisch-herxheimer reaction<br />
10:20 am - 10:27 am<br />
FP-27<br />
Chronic Sympathetic Ophthalmia: A Case Report<br />
Margarita Justine O. Bondoc, Analyn Suntay-Guerrero, Emerson<br />
Jay B. Molina, Alex U. Pisig, Egidio Jose S. Fortuna,<br />
Kristine Corpus<br />
Cardinal Santos Medical Center, Philippines<br />
Objective: To report a case <strong>of</strong> chronic sympathetic ophthalmia in<br />
a 44 year old female and its management.<br />
Methods: This is a case report.<br />
Results: A 44 year old female first seen 4 years prior after blunt<br />
trauma to the right eye resulted in blurring <strong>of</strong> vision on both eyes.<br />
Reduced visual acuity to counting fingers and finding <strong>of</strong> panuveitis<br />
on both eyes through flourescein angiography led to the diagnosis<br />
<strong>of</strong> sympathetic ophthalmia. She was treated with oral and topical<br />
steroids then 2 cycles <strong>of</strong> IV cyclophosphamide which resolved her<br />
symptoms. After 2 years <strong>of</strong> no follow up, she returned with good<br />
vision but with +1 cells on the left eye. Mild topical steroid was<br />
started. Flourescein angiography revealed no active inflammation<br />
or choroiditis. The steroid was then tapered and discontinued.<br />
Conclusion: Sympathetic ophthalmia is a bilateral, nonnecrotizing,<br />
granulomatous uveitis that can occur following<br />
ocular trauma or surgery. It is has an acute and chronic phase<br />
and can have exacerbations. Prompt assessment and treatment<br />
with corticosteroids and immunomodulating therapy should<br />
be instituted to increase the chances <strong>of</strong> regaining good visual<br />
function.<br />
Key Words: chronic sympathetic ophthalmia, recurrence,<br />
relapse, eye trauma<br />
FREE PAPER SESSION 3<br />
<strong>Meeting</strong> Rooms 4-6<br />
1:30 - 4:00 pm<br />
Chair: Rigo Daniel Reyes, MD<br />
Co-Chair: Ernesto Pangalangan, Jr., MD<br />
Glaucoma<br />
10:28 am - 10:35 am<br />
FP-28<br />
Ocular Toxoplasmosis among Filipino Patients seen at the<br />
East Avenue Medical Center: Clinical Manifestation and<br />
Effectiveness <strong>of</strong> Treatment<br />
Majourette Dy Varela, Jessica Marie R. Abaño<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
Objective: To determine the pr<strong>of</strong>ile <strong>of</strong> Ocular Toxoplasmosis<br />
among Filipino patients seen at the Department <strong>of</strong> Ophthalmology<br />
East Avenue Medical Center in terms <strong>of</strong> its clinical manifestation<br />
and the effectiveness <strong>of</strong> treatment from January 2007 to August<br />
<strong>2012</strong>.<br />
Methods: A retrospective descriptive study was conducted<br />
among patients with uveitis seen at a tertiary government hospital<br />
from January 2007 to August <strong>2012</strong>. All patients who were positive<br />
with toxoplasmosis titer were included in the study. Excluded<br />
were cases wherein toxoplasmosis was considered but titers<br />
were not available and cases with positive titers but treatment<br />
was not instituted due to default follow-up. The presenting ocular<br />
symptoms, treatment received and latest ocular findings were<br />
collected. Descriptive statistics was used to analyze the data.<br />
Results: Fourteen patients were identified with 4:3 male to female<br />
ratio and mean age <strong>of</strong> 41.07. The most common presentation<br />
was blurring <strong>of</strong> vision. Presenting visual acuity ranged from<br />
20/32 to counting fingers. Most common ocular findings were<br />
iritis and vitritis. All patients received the standard treatment for<br />
toxoplasmosis. Three cases were lost to follow-up in the course<br />
<strong>of</strong> the treatment. There was absence <strong>of</strong> iritis and vitritis as well<br />
as improved visual acuity among patients who had completed<br />
treatment. Two patients developed increased intraocular pressure<br />
that had been controlled by topical anti-glaucoma medication.<br />
Conclusions: Toxoplasmosis is a disease known to be the<br />
most common cause <strong>of</strong> retinochoirditis and in immunocompetent<br />
patient, is usually self-limiting. Treatment shortens the duration <strong>of</strong><br />
the disease and showed results <strong>of</strong> better visual prognosis at the<br />
end <strong>of</strong> treatment regimen. Patients should be well advised on the<br />
course <strong>of</strong> the disease and the benefits <strong>of</strong> a completed treatment.<br />
Key Words: Treatment, Filipino<br />
Oral Free Papers<br />
20
Oral Free Papers<br />
10:36 am - 10:43 am<br />
FP-29<br />
Intermediate Uveitis as an Initial Presentation <strong>of</strong> Sarcoidosis<br />
in an Adolescent Male<br />
Jacqueline T. Mupas, Jessica Marie R. Abaño<br />
University <strong>of</strong> Santo Tomas Hospital, Philippines<br />
Objective: To report a case <strong>of</strong> sarcoidosis, initially presenting as<br />
intermediate uveitis in an adolescent Filipino male.<br />
Methods: Case report.<br />
Results: This is a case <strong>of</strong> a 19-year-old male, who presented<br />
with bilateral uveitis when he was 13 years <strong>of</strong> age. On initial<br />
examination, he had minimal anterior segment inflammation with<br />
++ vitreous cells, macular edema and optic disc hyperaemia on<br />
both eyes. Chest x-ray was read as possible koch’s infection and<br />
PPD was positive at 22mm. Impression then was intermediate<br />
uveitis, possibly ocular tuberculosis. He was then referred to a<br />
pulmonologist who gave him quadruple anti-koch’s treatment. His<br />
ocular inflammation initially responded to topical and systemic<br />
medication but later became recurrent in nature. At this time, a<br />
pediatric rheumatologist cleared him <strong>of</strong> any systemic disease<br />
that might contribute to ocular inflammation. A year later, patient<br />
developed subcutaneous on both lower extremities for which he<br />
was treated with topical medications. His ocular inflammation<br />
would recur intermittently and he was treated with both topical<br />
and oral steroids whenever necessary. 2 years later, chest x-ray<br />
showed extensive PTB but sputum AFB were negative. He was<br />
again treated with anti-tuberculosis medication for 6 months. A<br />
year later he has swelling <strong>of</strong> the cheek and ulcerations on the<br />
legs. Biopsy showed granulomatous inflammation w/ some<br />
necrosis, AFB (-) PAS (-). Lung findings revealed hilar infiltrates.<br />
He was again referred to rheumatologist who then diagnosed him<br />
to have Sarcoidosis.<br />
Conclusion: Although relatively uncommon, sarcoidosis<br />
should be a differential diagnosis <strong>of</strong> tuberculosis in patients with<br />
recalcitrant uveitis associated with other systemic granulomatous<br />
inflammation. This is particularly important in regions where<br />
tuberculosis is epidemic and sometimes overdiagnosed.<br />
Key Words: tuberculosis, sarcoidosis, intermediate uveitis<br />
10:44 am - 10:51 am<br />
FP-30<br />
A Retrospective Study <strong>of</strong> the Incidence, Indications and<br />
Outcomes <strong>of</strong> Nd:YAG Capsulotomy in Eyes Implanted with<br />
and Accommodating IOL<br />
Angela Adelaida Samano¹, Rosalie Mae M. Reyes²<br />
¹Cardinal Santos Medical Center, ²Asian Eye Institute, Philippines<br />
Objective: To report the incidence <strong>of</strong> capsular changes in<br />
Crystalens-implanted eyes and analyze the indications and<br />
outcomes <strong>of</strong> yag capsulotomy.<br />
21<br />
Methods: We reviewed the records <strong>of</strong> 411 eyes <strong>of</strong> 258 patients<br />
implanted with the Crystalens IOL. Capsular change indications<br />
for yag capsulotomy were posterior capsular opacity (PCO),<br />
lens tilt and capsular striae. Eyes in each indication were further<br />
subdivided into therapeutic yag (TY) and prophylactic yag (PY)<br />
groups. Outcomes before and after yag capsulotomy were<br />
analyzed.<br />
Results: 90 <strong>of</strong> 411 crystalens-implanted eyes (21%) had<br />
undergone yag capsulotomy. 61 eyes had PCO, 12 had lens tilt<br />
and 17 had striae. 27 eyes belonged to the therapeutic (TY) and<br />
63 eyes to the prophylactic (PY) yag group. The mean interval<br />
between phacoemulsification and yag capsulotomy was 10<br />
months. In the TY PCO subgroup, UDVA changed from 20/40 preyag<br />
to 20/25 post-yag, UNVA from J3 to J2, MRSE from -0.43D<br />
to -0.2D. In the TY tilt subgroup, UDVA changed from 20/50 to<br />
20/30, UNVA was unchanged at J2 and MRSE from -1.21D to<br />
-0.89D. In the TY striae group, UDVA changed from 20/50 to<br />
20/30, UNVA from J3 to J2 and MRSE from 0.62D to -0.4D. In<br />
the PY PCO subgroup, UDVA was unchanged at 20/25, UNVA<br />
unchanged at J2 and MRSE changed from -0.52D to -0.47D. In<br />
the PY tilt subgroup, UDVA changed from 20/25 to 20/20, UNVA<br />
was unchanged at J2 and MRSE changed from -0.87D to -0.45D.<br />
In the PY striae subgroup, UDVA was unchanged at 20/30, UNVA<br />
changed from J3 to J2 and MRSE changed from -0.62D to -0.7D.<br />
Conclusion: Capsular changes occur after Crystalens<br />
implantation which necessitate yag capsulotomy. Once vision<br />
has deteriorated, a therapeutic yag treatment can help improve<br />
vision. If capsular changes have occurred but vision has not<br />
deteriorated, a prophylactic yag capsulotomy can stabilize visual<br />
and refractive outcomes.<br />
Key Words: Crystalens, Nd:YAG laser posterior capsuolotomy,<br />
Accommodating IOL, Posterior capsular opacity<br />
10:52 am - 10:59 am<br />
FP-31<br />
Refractive and Visual Outcomes <strong>of</strong> Surgical Treatments for<br />
High Myopia Patients<br />
Ma. Rachelle Katrina C. Solis, Robert Edward T. Ang<br />
Cardinal Santos Medical Center, Philippines<br />
Objective: To present the refractive and visual outcomes <strong>of</strong><br />
refractive surgical treatment options used in high myopia patients.<br />
Methods: This is a retrospective review <strong>of</strong> patients diagnosed<br />
with high myopia (MRSE >/= -6.00D) who underwent one <strong>of</strong><br />
the following procedures: Laser In Situ Keratomileuis (LASIK),<br />
Photorefractive Keratectomy (PRK), phakic IOL implantation<br />
with the Staar Implantable Collamer Lens (ICL) or Alcon Cachet<br />
Phakic IOL. Eyes with BDVA <strong>of</strong> less than 20/30 due to amblyopia<br />
or eye pathologies were excluded from the study.<br />
Results: This study evaluated 145 eyes <strong>of</strong> 77 patients. 86<br />
eyes underwent LASIK; 37 eyes underwent PRK; 16 eyes<br />
were implanted with the STAAR ICL and 6 eyes with Acrys<strong>of</strong><br />
Cachet lens. Preoperatively, the mean MSRE <strong>of</strong> the LASIK
group was -7.44D, the PRK group was -7.71D, the STAAR ICL<br />
group was -9.82D and the Cachet group was -12.08D. At 1 year<br />
postoperatively, the mean MRSE was -0.22D for the LASIK group,<br />
+0.23D for the PRK group, -0.40D for the STAAR ICL group and<br />
-0.28D for the Cachet group. The mean UDVA at 1 year follow-up<br />
was 20/20 in the LASIK and PRK groups, 20/25 in the STAAR<br />
ICL group and 20/30 in the Cachet group, while the BDVA was<br />
20/20 in all groups. An increase in spherical aberration (SA) and<br />
total higher order aberration (HOA) was observed in LASIK (SA<br />
p=0.00; HOA p=0.00) and PRK (SA p=0.00; HOA p=0.00) but<br />
not in the STAAR ICL (SA p=0.11; HOA p=0.69) and Cachet (SA<br />
p=0.95; HOA p=0.25) groups.<br />
Conclusion: The four refractive treatment options were effective<br />
at reducing the myopic refractive error and achieving good<br />
uncorrected distance vision. Laser refractive treatments cause an<br />
increase in spherical and higher order aberrations not seen in the<br />
phakic IOL treatments.<br />
Key Words: Laser In Situ Keratomileusis (LASIK), Photorefractive<br />
Keratectomy (PRK), Cachet, Phakic IOL<br />
1:30 pm - 1:37 pm<br />
FP-32<br />
Preliminary Report on the Incidence <strong>of</strong> Steroid-induced<br />
Ocular Hypertension in Patients in a Tertiary Hospital: A<br />
5-year Prospective Study<br />
Victoria Anne A. Yao, Ma. Margarita Lat-Luna, Juan S. Lopez<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines<br />
Objective: To determine the incidence <strong>of</strong> steroid induced ocular<br />
hypertension among patients in the Department <strong>of</strong> Ophthalmology<br />
and Visual Sciences, Sentro Oftalmologico, Philippine General<br />
Hospital from January <strong>2012</strong> to January 2017<br />
Methods: A prospective, observational, non-randomized<br />
study among patients who are and will be administered topical,<br />
periocular, intravitreal and systemic steroids, aged 10 years old<br />
and above, is being used in this study. The incidence <strong>of</strong> steroidinduced<br />
ocular hypertension was measured and compared<br />
according to the different routes <strong>of</strong> administration.<br />
Results: Twenty patients were recruited into the study. Among<br />
the 27 eyes 6 had an increase in intraocular pressure 24mmHg<br />
with a total incidence <strong>of</strong> 22%. A higher proportion <strong>of</strong> male eyes<br />
were noted (29%) compared to female eyes (10%). The mean<br />
age <strong>of</strong> eyes with steroid-induced ocular hypertension is 27±7<br />
years which is lower compared to eyes without steroid-induced<br />
ocular hypertension (39±15 years). The mean baseline IOP is<br />
slightly higher (14.7±1.5) compared to those without steroidinduced<br />
ocular hypertension (12.4±2.5) (p=0.0567). Mean vertical<br />
cup-to-disc ratio among eyes with steroid ocular hypertension<br />
is 0.5 while the mean vertical cup-to-disc ratio <strong>of</strong> eyes without<br />
steroid induced ocular hypertension is 0.4±0.08 (p=0.0253). The<br />
incidence seems to be higher among those with combination<br />
(33%) as compared to those on topical steroids (22%). Upon<br />
administration <strong>of</strong> the steroids 2 <strong>of</strong> the patients had increase in<br />
intraocular pressure after 1 week, one patient after 2 weeks, one<br />
patient after one month and one patient after 2 months.<br />
Conclusion: A 22% incidence <strong>of</strong> steroid-induced ocular<br />
hypertension was demonstrated. Higher incidence <strong>of</strong> steroidinduced<br />
ocular hypertension were seen among males, <strong>of</strong> younger<br />
age and with greater baseline vertical cup-to-disc ratio. Use <strong>of</strong><br />
a combination <strong>of</strong> steroids was noted to cause an increase in<br />
intraocular pressure more than the topical or periocular routes.<br />
Key Words: steroid-induced, ocular hypertension<br />
1:38 pm - 1:45 pm<br />
FP-33<br />
Oral Free Papers<br />
Comparison <strong>of</strong> Trabeculectomy with Mitomycin-C and<br />
Glaucoma Drainage Device Implantation in Glaucoma<br />
Management after Penetrating Keratoplasty<br />
Meliza Katrina B. Agulto, Rainier Victor A. Covar<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines<br />
Objective: The management <strong>of</strong> glaucoma post penetrating<br />
keratoplasty is difficult particularly when medical treatment<br />
has failed. Surgery is the next step particularly in intractable<br />
glaucoma. Surgical treatment options for patients post<br />
penetrating keratoplasty include trabeculectomy with or without<br />
anti-metabolites, drainage devices, and cycloablation. Secondary<br />
glaucomas have poorer visual outcomes, and limited treatment<br />
options. Thus treatment is a challenge. This study was done<br />
to compare surgical outcomes in terms <strong>of</strong> intraocular pressure<br />
control <strong>of</strong> trabeculectomy with mitomycin-C and glaucoma<br />
drainage device implantation and determine appropriate surgical<br />
management in glaucoma control in post-penetrating keratoplasty<br />
patients.<br />
Methods: This is a retrospective study where a review <strong>of</strong><br />
medical records <strong>of</strong> patients who developed glaucoma after<br />
penetrating keratoplasty and underwent either trabeculectomy<br />
with mitomycin-C or glaucoma drainage device implantation to<br />
control the glaucoma between October 2006 to June <strong>2012</strong> at<br />
the Department <strong>of</strong> Ophthalmology, University <strong>of</strong> the Philippines-<br />
Philippine General Hospital was done. The following information<br />
was documented for each patient: age, gender, corneal diagnosis<br />
before keratoplasty, details <strong>of</strong> keratoplasty in terms <strong>of</strong> graft versus<br />
donor size, other simultaneous operations, visual acuity (VA),<br />
intraocular pressure (IOP), number <strong>of</strong> glaucoma medications<br />
before and after PKP, graft status before glaucoma treatment<br />
and at the final visit, type <strong>of</strong> glaucoma before treatment, and the<br />
glaucoma procedure performed and its complications if any. Three<br />
primary outcomes were evaluated: graft status, postoperative IOP,<br />
and VA. Controlled IOP with or without medications was defined<br />
as IOP greater than 6 but less than 20. Summary <strong>of</strong> quantitative<br />
data were expressed in mean, standard deviation and range.<br />
Paired t-test was used to determine significant decrease in the<br />
mean IOP control and number <strong>of</strong> medications before and after<br />
keratoplasty. Single-factor analysis <strong>of</strong> variance (ANOVA) was<br />
used to determine if there are significant differences in the mean<br />
between the two surgeries. Mc Nemar’s Test and generalized<br />
Fisher’s exact test were also used to compare percentages.<br />
Kaplan-Meier survival analysis was used to compare the<br />
22
Oral Free Papers<br />
surgeries in its effect to graft clearance. All the statistical tests<br />
were performed using SAS 9.0. P-values less than 0.05 indicate<br />
significant difference.<br />
Results: Out <strong>of</strong> the 222, 25 charts met the study’s criteria.<br />
Sixteen (55.1%) had clear graft after the surgery; 12 (48%) corneal<br />
graft status was the same pre- and post- glaucoma surgery.<br />
Eleven (78.6%), and 11 (100%) underwent trabeculectomy<br />
with mitomycin-C, and GDD had controlled IOP. No significant<br />
difference (p = 0.069) in percentage <strong>of</strong> patients with IOP control<br />
between the two groups. Mean IOP <strong>of</strong> patients under the Trab<br />
MMC [32.6 ± 14.4 to 15.1 ± 13.2, p = 0.002] and GDD group<br />
[22.8 ± 15.7 to 12.7 ± 2.5, p = 0.035] significantly decreased. The<br />
decrease in mean IOP <strong>of</strong> the two groups did not differ [p=0.553]<br />
significantly. Using Mc Nemar’s, patients in the Trab MMC group<br />
(p=0.004) with IOP <strong>of</strong> 6 to 20 mmHg significantly increased<br />
(14.3% to 78.6%). In the GDD group, the number <strong>of</strong> patients<br />
with IOP <strong>of</strong> 6 to 20 mmHg (72.7% to 100%) and the number <strong>of</strong><br />
patients with IOP <strong>of</strong> more than 20 mm Hg (27.3% to 0%) did not<br />
change significantly (p=0.250). Before [p = 0.724] surgery, there<br />
is no significant difference in number <strong>of</strong> medications taken by<br />
both groups. After surgery both groups significantly reduced the<br />
mean number <strong>of</strong> medications. The mean number <strong>of</strong> months that<br />
a patient treated with Trab MMC and GDD will have a controlled<br />
IOP are 12.5 ± 1.9 and 14.5 ± 6.4 respectively. Log Rank test [p<br />
= 0.847] indicated that the surgeries do not differ in the number <strong>of</strong><br />
months to have controlled IOP.<br />
Conclusions: The two surgical procedures <strong>of</strong> trabeculectomy<br />
with mitomycin-C and glaucoma drainage device implantation<br />
are effective methods <strong>of</strong> controlling IOP post keratoplasty. There<br />
was no significant difference between the two groups with respect<br />
to controlling IOP. These two methods were able to supplement<br />
aqueous outflow in patients post keratoplasty. Although IOP<br />
increased months after keratoplasty these surgeries were able<br />
to lower IOP and lower the amount <strong>of</strong> medications needed by<br />
the patient to achieve IOP control as compared to pre- glaucoma<br />
surgery. It was notable that visual acuity and graft status did not<br />
significantly alter or deteriorate post- glaucoma surgery.<br />
Key Words : glaucoma, glaucoma drainage device, penetrating<br />
keratoplasty, trabeculectomy with mitomycin-C<br />
1:54 pm - 2:01 pm<br />
FP-35<br />
Malignant Glaucoma Post Pars Plana Vitrectomy with<br />
Intraocular Lens Retrieval<br />
Ian Ben M. Batcagan<br />
Quirino Memorial Medical Center, Philippines<br />
Objective: To present a d discuss a case <strong>of</strong> a 60 year old female<br />
who developed malignant glaucoma post pars plana vitrectomy<br />
and intraocular lens retrieval. To emphasize the importance <strong>of</strong> a<br />
thorough ophthalmic evaluation, diagnosis and management <strong>of</strong><br />
this case<br />
Methods: Case Report Setting: Tertiary Government Hospital<br />
Patient: One<br />
23<br />
Results: This is a case <strong>of</strong> a 64 year old female who underwent<br />
extracapsular cataract extraction with posterior chamber<br />
intraocular lens implantation (IOL). The surgery was uneventful,<br />
however, on follow up it was noted that the patient’s lens implant<br />
was not in place and was in the vitreous cavity. A small retinal<br />
tear was also noted. The patient underwent pars plana vitrectomy<br />
with IOL retrieval, cryoretinopexy and perfluoropropane infusion.<br />
Five days post operatively the patient developed severe eye pain.<br />
Consult was done. It was noted that anterior chamber was shallow<br />
and that the intraocular pressure was 35 mmHg. The retina was<br />
unremarkable. The patient was given brimonidine eye drops. On<br />
follow up, 12 days post IOL retrieval, the chamber still shallow<br />
and intraocular pressure was 42 mmHg. Dorzolamide and timolol<br />
maleate was added to the patient medications. Laser Iridotomy<br />
(LI) was done. Intraocular pressure was monitored post LI. The<br />
pressure was still ranging from 12-42mmHg. An Ultrasound<br />
biomicroscopy was done and revealed supraciliary effusion, a<br />
posterior capsule-iris diaphragm and malrotation <strong>of</strong> the ciliary<br />
body. A diagnosis <strong>of</strong> malignant glaucoma was made. At this point<br />
the plan was to drain the supraciliary fluid, remove the perfluoron<br />
infused, and goniosynechiolysis to create a communication<br />
between the vitreous and the anterior chamber. The patient then<br />
underwent the proposed procedure. Postoperatively the patient’s<br />
IOP was noted to be 12 mmHg and the anterior chamber was<br />
deep.<br />
Conclusion: Malignant glaucoma treatment still remains a<br />
challenge because <strong>of</strong> the limited understanding <strong>of</strong> its etiology.<br />
Whatever pathogenesis for the development <strong>of</strong> malignant<br />
glaucoma is important to establish a communication between the<br />
anterior chamber and vitreous and that it involves the interplay <strong>of</strong><br />
the ciliary process, lens and anterior vitreous.<br />
Key Words: Malignant glaucoma, aqueous misdirection, pars<br />
plana vitrectomy, ultrasound biomicroscopy<br />
2:02 pm - 2:09 pm<br />
FP-36<br />
Correlation between the Average Retinal Nerve Fiber Layer<br />
Thickness and Rim Area Value <strong>of</strong> the Cirrus OCT with the<br />
Humphrey Visual Field Index Value<br />
Andrei P. Martin<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
Objective: To examine the correlation between the average<br />
retinal nerve fiber layer (RNFL) thickness and visual field index<br />
(VFI), as well as the correlation <strong>of</strong> rim area (RA) and VFI.<br />
Methods: This retrospective study was performed on 121 eyes<br />
<strong>of</strong> 87 patients who are diagnosed cases <strong>of</strong> glaucoma. All eyes<br />
underwent examination by the Cirrus OCT and the Humphrey<br />
visual field analyzer. The correlation <strong>of</strong> VFI and RNFL thickness,<br />
and VFI and RA were analyzed in all eyes. The Spearman’s rank<br />
correlation coefficient was used for analysis.<br />
Results: A positive correlation (0.9987) between RNFL thickness<br />
and VFI was seen in all eyes. RA and VFI also showed a positive<br />
correlation (0.9992) in all eyes.
Conclusion: Both the average retinal nerve fiber layer thickness<br />
and the rim area value <strong>of</strong> the Cirrus OCT have a positive<br />
correlation with the Humphrey visual field index value.<br />
Key Words: RNFL thickness, rim area, visual field index,<br />
Glaucoma, Cirrus OCT<br />
2:10 pm - 2:17 pm<br />
FP-37<br />
The Effect <strong>of</strong> Direct Cold Compress on Intraocular Pressure<br />
in Healthy Subjects<br />
Niccolo Zandro Valencia, Mario M. Yatco, Ian Ethelbert Dy<br />
University <strong>of</strong> Sto. Tomas Hospital, Philippines<br />
Objective: To investigate the effect <strong>of</strong> direct cold compress on<br />
intraocular pressure (IOP) in normal subjects.<br />
Methods: A randomized Controlled Trial; Thirty eyes from fifteen<br />
healthy volunteers; One eye <strong>of</strong> each <strong>of</strong> the fifteen subjects was<br />
randomly chosen as the experimental eye. The other eye, which<br />
also remained closed was not subjected to the cold compress<br />
and served as the control eye: IOP were measured in thirty<br />
eyes <strong>of</strong> fifteen healthy volunteer subjects before and after the<br />
application <strong>of</strong> direct cold compress using an ice-filled zip lock<br />
with a temperature <strong>of</strong> 20-25 degrees Celsius. IOP was measured<br />
using the Goldmann Applanation tonometer after 5 minutes<br />
<strong>of</strong> compress and then after 15 minutes <strong>of</strong> compress, while the<br />
temperature <strong>of</strong> the cold compress was taken using an ordinary<br />
laboratory alcohol thermometer during the 1st minute <strong>of</strong> each<br />
compress. Data was then analyzed using t-test for dependent<br />
and independent variable.<br />
Results: After application <strong>of</strong> cold compress for 5 minutes, the<br />
mean IOP on the experimental eyes decreased from a baseline<br />
<strong>of</strong> 17.17 mmHg to 14.51 (P< 0.014) and after 15 minutes, to 13.15<br />
mmHg (P
Oral Free Papers<br />
and severity <strong>of</strong> Pediatric Ocular Trauma Cases seen in a tertiary<br />
hospital for four months, to establish the visual outcomes <strong>of</strong><br />
the cases and to determine prognostic factors that affected the<br />
outcomes <strong>of</strong> pediatric ocular injuries.<br />
Methods: This was a prospective, observational study done at<br />
the Department <strong>of</strong> Ophthalmology and Visual Sciences <strong>of</strong> the<br />
Philippine General Hospital from January to April <strong>2012</strong>. Pediatric<br />
patients aged 0-18 who came in to the Emergency Clinic for<br />
ocular trauma were referred to the study. Eighty six (86) patients<br />
were included in the study. Patients were examined on initial<br />
consult and computed for the Ocular Trauma Score by converting<br />
the OTS variables into OTS categories as performed in the OTS<br />
study. Patients were followed up after 1-, 2- and 3 months after<br />
initial consult. The distribution <strong>of</strong> percentage <strong>of</strong> final visual acuity<br />
was compared between the OTS study and our result. Descriptive<br />
and correlation statistics were performed to determine prognostic<br />
factors affecting visual outcomes.<br />
Results: In our setting, there was male predominance<br />
(76%), mostly occurring in 2-6 age group (37%). Injuries were<br />
predominantly accidental (91%) occurring at home (72%). Majority<br />
were caused by blunt trauma (55%) followed by penetrating<br />
injuries (21%). Majority <strong>of</strong> the patients (76.2%) had no impairment<br />
while 14% had severe visual impairment after three months.<br />
There was 88.39% agreement (p=0.05) <strong>of</strong> the OTS predicted<br />
visual acuity with the final visual acuity in the study. Factors that<br />
affected the outcomes included initial visual acuity, penetrating<br />
injuries, endophthalmitis and retinal detachment.<br />
Conclusion: Ocular trauma is a common cause <strong>of</strong> visual<br />
impairment in children and can be prevented. There should be<br />
preventive measures, better supervision, public education and<br />
aggressive and prompt management to improve visual outcomes.<br />
Key Words: ocular trauma, pediatric ocular trauma, ocular trauma<br />
score, visual prognosis..<br />
FP-40<br />
2:45 pm - 2:52 pm<br />
Ophthalmologic Findings in Hunter Syndrome<br />
Frances Marie DC. Roa, Marissa N. Valbuena,<br />
Mary Ann R. Abacan, Mary Anne D. Chiong<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines<br />
Objective: To identify the eye findings <strong>of</strong> patients diagnosed with<br />
Hunter Syndrome and to correlate the severity <strong>of</strong> ocular findings<br />
with that <strong>of</strong> the disorder.<br />
Methods: A Descriptive Analysis was done on 15 patients,<br />
with a mean age <strong>of</strong> 11 years. All patients were diagnosed with<br />
Mucopolysaccharidoses Type II or Hunter Syndrome using<br />
specific enzyme assays from plasma and leukocytes. All patients<br />
underwent ophthalmologic examination including visual acuity<br />
(VA), eye motility, refraction, slit-lamp examination, tonometry<br />
and indirect ophthalmoscopy.<br />
Results: All patients manifested with refractive error, the most<br />
common being hyperopia (13/15 or 86.7%). Two patients<br />
25<br />
presented with strabismus. Tessellated retinas were observed<br />
in 5 (33.3%) patients, while pigmentary retinopathy was found<br />
in 2 (13.3%). Bilateral large cup-to-disc ratios were seen in 3<br />
(20%) individuals. Nonetheless, there was functional vision<br />
in all <strong>of</strong> the subjects that could be examined, as evidenced by<br />
their independence in day-to-day activities. Patients with errors<br />
<strong>of</strong> refraction corrected with spectacles reported improvement in<br />
their schooling.<br />
Conclusion: The results showed that all individuals with Hunter<br />
syndrome have ophthalmological abnormalities. Eye pathologies<br />
may go undetected or unmanaged in the presence <strong>of</strong> other more<br />
life-threatening problems. In individuals with a more gradual<br />
course, however, early detection and management <strong>of</strong> eye<br />
problems can have a pr<strong>of</strong>ound impact on quality <strong>of</strong> life. Given the<br />
progressive nature <strong>of</strong> the disorder, regular follow up in the setting<br />
<strong>of</strong> integrated care is warranted. The goal <strong>of</strong> the ophthalmologist is<br />
not only to maximize vision but also to curtail to the patient’s age,<br />
mental capability and physical state.<br />
Key Words: Eye pathology, Hunter Syndrome,<br />
Mucopolysaccharidoses II<br />
2:53 pm - 3:00 pm<br />
FP-41<br />
A Preliminary Report on the Efficacy <strong>of</strong> Occlusion Therapy<br />
Versus Observation for Pediatric Intermittent Exotropia:<br />
A Single-Blind Randomized Controlled Trial<br />
Ma Patricia Therese R. Fellizar, Marissa N. Valbuena,<br />
Melissa Anne M. Santos<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines<br />
Objective: To determine the efficacy <strong>of</strong> occlusion therapy for<br />
intermittent exotropia among patients aged 5-18 years.<br />
Methods: This is a single-center, single blind prospective<br />
interventional randomized study. Twenty eight pediatric patients<br />
diagnosed with small angle, good to fair control intermittent<br />
exotropia with best corrected visual acuity <strong>of</strong> 20/50 or better were<br />
included in the study and randomized into 2 groups: Observation<br />
Group where no treatment was prescribed; and Occlusion Group<br />
where patching <strong>of</strong> the non-deviating eye with a flannel cloth for 3<br />
hours a day for 6 weeks was prescribed. Follow-up was done at<br />
the first, third, sixth, and twelfth week on treatment and at 1 month<br />
post-treatment. Outcome measures were the best corrected<br />
visual acuity (BCVA), angle <strong>of</strong> deviation, stereoacuity using the<br />
Titmus Fly Test, and degree <strong>of</strong> control <strong>of</strong> exotropia using the<br />
Newcastle Control Score (NCS).<br />
Results: There was significant improvement <strong>of</strong> all outcome<br />
measures in both groups over time. There was significantly<br />
better stereoacuity and degree <strong>of</strong> control in the Occlusion Group<br />
compared to the Observation Group in all follow-up periods.<br />
There was no significant difference in BCVA for OD (p=0.5253),<br />
BCVA for OS (p=0.8075), angle <strong>of</strong> deviation at near (p=0.4679),<br />
angle <strong>of</strong> deviation at distance (p=0.1347), NCS clinic control for<br />
near (p=0.8939), and NCS total (p=0.3388) between groups.
Conclusions: Although this study is still currently on going, the<br />
preliminary data shows that there was improvement in all outcome<br />
measures for both occlusion and observation alone over time. It<br />
was observed that there was more improvement in stereoacuity<br />
and in degree <strong>of</strong> control with the Occlusion Group compared with<br />
the Observation Group. Therefore, both occlusion and observation<br />
are effective managements for intermittent exotropia. However,<br />
occlusion therapy is more effective in improving stereoacuity and<br />
degree <strong>of</strong> control <strong>of</strong> pediatric patients with intermittent exotropia<br />
compared to observation alone.<br />
Key Words: intermittent exotropia, occlusion therapy, patching,<br />
occlusion, efficacy<br />
3:01 pm - 3:08 pm<br />
FP-42<br />
Eventual Outcomes <strong>of</strong> Retinopathy <strong>of</strong> Prematurity Screening<br />
at a Tertiary Government Hospital: A Five Year Study<br />
Emmeline M. Alvarez, Ricardo Ventura<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
Objective: To determine the eventual outcomes <strong>of</strong> retinopathy<br />
(ROP) screening at a tertiary government hospital in Quezon City,<br />
Manila, Philippines<br />
Methods: A retrospective chart review <strong>of</strong> retinopathy <strong>of</strong><br />
prematurity patients at a tertiary government hospital from<br />
January 2008 to July <strong>2012</strong> was done. Eventual outcomes <strong>of</strong> our<br />
center’s ROP screening were analyzed.<br />
Results: A total <strong>of</strong> 388 eyes <strong>of</strong> 194 premature infants were<br />
included in the study. Two hundred ninety-six (76.28%) eyes<br />
had no ROP and 92 (23.71%) eyes were diagnosed with ROP.<br />
Thirty-two (10.81%) eyes without Rop were able to have a followup<br />
exmination at our center. Thirty-fiv (38.08%) with ROP were<br />
classified as stage 2, followed by 23 cases (25.00%) with stage<br />
1 and 13 cases (14.13%) with stae 3 as based on ICROP. Fiftythree<br />
eyes with rOP were able to have follow-up examinations<br />
and <strong>of</strong> which 26 eyes with rop were able to receive treatment and<br />
27 eyes wih cycloplegic refraction. Thirteen eyes (48.15%) were<br />
hyperope, 12 eyes (44.44%) were myope and two eyes (7.40%)<br />
were emmetrope.<br />
Conclusion: There is a low follow-up rate for premature infants<br />
who underwent ROP screening at our center. The importance <strong>of</strong><br />
a regular and timely follow-up examination should be stressed<br />
to parents and referring physicians in order to monitor visual<br />
development <strong>of</strong> these patients. Appropriate treatment can be<br />
advised and administered as well. Errors <strong>of</strong> refraction can also<br />
be addressed for proper visual maturation and prevention <strong>of</strong><br />
amblyopia.<br />
Key Words: retinopathy <strong>of</strong> prematurity, eventual outcomes,<br />
follow-up rate, refractive outcomes<br />
3:09 pm - 3:16 pm<br />
FP-43<br />
Effect <strong>of</strong> Pediatric Eye Screening Checklist and Training on<br />
Ophthalmology Referrals in QMMC, a 1-year Study<br />
Ian Ben M. Batcagan<br />
Quirino Memorial Medical Center, Philippines<br />
Objective: To assess whether an eye screening checklist and a<br />
short training course result in an increase in appropriate referrals<br />
<strong>of</strong> suspicious ophthalmologic abnormalities in the pediatric age<br />
group.<br />
Methods: Pediatric residents were given a 3-part lecture in<br />
conducting ophthalmologic pediatric evaluation. A pediatric eye<br />
screening checklist, based on the 2002 American Academy <strong>of</strong><br />
Ophthalmology Pediatric Eye Evaluations Preferred Practice<br />
Patterns and 2002 American Academy <strong>of</strong> Pediatrics Eye Vision<br />
Screening Recommendations for Primary Care Providers, was<br />
made available to the pediatric residents. All patients from the outpatient,<br />
nursery and ward were screened. All high risk patients,<br />
premature, family history <strong>of</strong> ophthalmologic problems and neurodevelopmental<br />
delay are excluded from the study. The patients<br />
referred are then assessed by the ophthalmology residents<br />
whether these patients are appropriate referrals. Appropriateness<br />
<strong>of</strong> referral was determined before and after the interventions and<br />
later compared.<br />
Results: Results showed a 13.8% increase the number <strong>of</strong><br />
appropriate referrals the post intervention group. There was<br />
a marked increase <strong>of</strong> appropriate referrals in the following<br />
age groups new born to 2 years old and 6 - 12 years, and the<br />
differences from the intervention group in these age groups are<br />
21.57% and 22.03% respectively.<br />
Conclusion: Pediatric screening is important in the early<br />
detection <strong>of</strong> ophthalmologic problems so that an early treatment<br />
or intervention may be initiated to avoid devastating outcomes. By<br />
providing an eye screening checklist and a short course training<br />
<strong>of</strong> pediatric residents can help in the detection <strong>of</strong> ophthalmologic<br />
conditions and familiarize pediatric residents to the ophthalmologic<br />
screening test.<br />
Key Words: pediatric eye screening<br />
Oral Free Papers<br />
26
3:17 pm - 3:24 pm<br />
FP-44<br />
Four Year Prevalence and Outcome <strong>of</strong> Initial Screening for<br />
Retinopathy <strong>of</strong> Prematurity (ROP) at the Clinical Division <strong>of</strong><br />
a Tertiary Hospital<br />
James Rommet Luz, Marcelino D. Banzon, Almira A. Manzano<br />
University <strong>of</strong> Sto. Tomas Hospital, Philippines<br />
Objective: To determine the 4 year prevalence and outcome<br />
<strong>of</strong> initial screening for ROP among newborn infants referred to<br />
the Department <strong>of</strong> Ophthalmology Clinical Division <strong>of</strong> a Tertiary<br />
Hospital.<br />
Methods: This is a retrospective study involving review <strong>of</strong><br />
medical records <strong>of</strong> infants screened for ROP from August 1, 2008<br />
to July 31, <strong>2012</strong> at a tertiary hospital. The study focused on the<br />
findings on initial examination and outcomes on follow up post<br />
discharge at the Out-Patient Department (OPD). Prevalence<br />
was determined using frequencies and percentages. Statistical<br />
analysis to correlate ROP to age <strong>of</strong> gestation and birth weight<br />
were done using Chi Square Test.<br />
Results: Fifty eyes <strong>of</strong> 25 infants were included in the study<br />
comprised <strong>of</strong> 9 boys and 16 girls with mean birth weight (BW)<br />
<strong>of</strong> 1318 grams and mean age <strong>of</strong> gestation (AOG) <strong>of</strong> 31 weeks.<br />
Nine eyes were positive for ROP. One eye had stage 4 zone 2<br />
ROP with plus disease. Three eyes had stage 3 ROP with plus<br />
disease. Five eyes had Stage 1 zone 3 ROP. Regression was<br />
noted on follow-up. Statistical analysis revealed no significant<br />
correlation <strong>of</strong> BW and ROP staging (2= 6.49711, = 9.48773) but<br />
noted significant correlation between AOG and ROP staging (2=<br />
13.69014, = 9.48773).<br />
Conclusion: Despite the increasing prevalence <strong>of</strong> retinopathy <strong>of</strong><br />
prematurity worldwide, only a relatively minimal number <strong>of</strong> infants<br />
were identified on initial screening done in the institution over<br />
the years 2008 to <strong>2012</strong>. Although only a few <strong>of</strong> these patients<br />
came back for follow up, those who were seen showed significant<br />
improvement from baseline. There is significant correlation<br />
between age <strong>of</strong> gestation and retinopathy <strong>of</strong> prematurity staging,<br />
congruent to previous studies. However, this study showed no<br />
correlation between birth weight and ROP staging.<br />
Key Words: Initial screening, Retinopathy <strong>of</strong> Prematurity,<br />
Prevalence, outcome <strong>of</strong> initial screening<br />
27<br />
Oral Free Papers<br />
3:25 pm - 3:32 pm<br />
FP-45<br />
Cycloplegic Effectiveness <strong>of</strong> Single-Dose Atropine 0.5%<br />
Compared with Three-Day Atropinization in Determining<br />
Error <strong>of</strong> Refraction in Children<br />
Anna Theresa G. Fernando, Fay Charmaine S. Cruz<br />
University <strong>of</strong> the East Ramon Magsaysay Memorial Medical<br />
Center Inc., Philippines<br />
Objective: The aim <strong>of</strong> the study is to compare the efficacy <strong>of</strong><br />
single-dose Atropine 0.5% (half percent <strong>of</strong> Isopto® Atropine 1%)<br />
with 3-day atropinization (Atropine 1.0%, Isopto® Atropine 1%) as<br />
a cycloplegic agent in determining error <strong>of</strong> refraction in children.<br />
Methods: The study is a randomized, prospective clinical trial. A<br />
total <strong>of</strong> twenty-two (22) children (44 eyes) ages 4 to 12 years old,<br />
with a mean age <strong>of</strong> 7.82 + 2.68 years seen at University <strong>of</strong> the<br />
East Ramon Magsaysay Memorial Medical Center (UERMMMC)<br />
Outpatient Department from June to September <strong>2012</strong>, were<br />
included in the study. Children were randomized to two (2) groups<br />
using a computer-generated method. Group 1 was given a single<br />
dose <strong>of</strong> Atropine 0.5% and group 2 was given 3-day atropinization<br />
(Atropine 1%) prior to refraction. All subjects had refraction done<br />
using the Grand Seiko Refractometer GR-3100K before and<br />
after instillation <strong>of</strong> the cycloplegic agent. The subjects? visual<br />
acuity and pupil diameter were also recorded every 2 days. The<br />
differences between the two groups were then analyzed using the<br />
SPSS Independent Samples T-Test.<br />
Results: The mean excess refraction uncovered by Atropine<br />
0.5% was 0.3864 D, whereas the mean hyperopia uncovered by<br />
Atropine 1% was 0.4205 D. The difference between the means<br />
is -0.03409, which is not statistically significant (P < 0.05). The<br />
cycloplegic effect <strong>of</strong> Atropine 1% was noted to last between 7<br />
to14 days, while that <strong>of</strong> Atropine 0.5% lasted 2 to 3 days.<br />
Conclusion: We conclude that Atropine 0.5% is <strong>of</strong> comparable<br />
efficacy to 3-day application <strong>of</strong> Atropine 1% in performing<br />
cycloplegic refraction in children.<br />
Key Words: cycloplegic refraction, Atropine 0.5%, 3-day<br />
atropinisation, error <strong>of</strong> refraction
External Disease and Cornea<br />
PP-1<br />
Bilateral Peripheral Ulcerative Keratitis in an Anti-nuclear<br />
Antibody (ANA) Positive 16 year-old Female: A Case Report<br />
Abigail O. Panganiban, Kate Concepcion-Torio,<br />
Jennifer Aurea S. Sarmiento<br />
Cardinal Santos Medical Center, Philippines<br />
Objective: This is the case <strong>of</strong> a 16 year-old female, who noticed<br />
occasional eye redness, blurring <strong>of</strong> vision and whitish opacities<br />
around the cornea on both eyes 2 years prior to initial consult.<br />
Methods: Baseline uncorrected visual acuity (UCVA) was 20/25<br />
OD and 20/20 OS, best corrected to 20/20 OU with the following<br />
manifest refraction spherical equivalent (MRSE) <strong>of</strong> -0.50 OD.<br />
Slitlamp examination showed perilimbal corneal thinning OU<br />
with minimal neovascularisation and conjunctival hyperemia OU.<br />
Other external eye exam findings, anterior segment findings and<br />
posterior segment were normal. Patient was referred to External<br />
Diseases and Cornea Service with the assessment <strong>of</strong> Peripheral<br />
Ulcerative Keratitis OU and was started on fluorometholone eye<br />
drops TID, OU.<br />
Results: Subsequent follow-ups revealed gradual progressive<br />
blurring <strong>of</strong> vision 20/50 OD and 20/30 OS, with concomitant<br />
myopic shift in manifest refraction spherical equivalent (MRSE)<br />
to -0.63 OD, and -0.38 OS. An inferior descemetocele was noted<br />
OD. Congested perilimbal neovascularization was noted to be<br />
greater on OD. Patient was started with Ofloxacin + Prednisolone<br />
(Exopred) eyedrops TID for 1 week and underwent 0.3 cc<br />
subconjunctival triamcinolone acetonide injection OD inferiorly<br />
and 0.2 cc superiorly. Patient was advised autoimmune disease<br />
work-up. Purified Protein Derivative (PPD), Chest Xray and Antinuclear<br />
antibody (ANA) testing were requested. PPD and chest<br />
Xray were negative while ANA was noted to be positive.<br />
Conclusion: She was referred to Pediatric service for further<br />
systemic evaluation and management. She was maintained on<br />
the pure topical antibiotic eye drops and was advised to follow up<br />
every 3 months.<br />
Key Words: Peripheral Ulcerative Keratitis, Systemic Lupus<br />
Erythematosus, Rheumatoid Arthritis, Autoimmune Disease,<br />
Keratolysis, Anti-nuclear Antibody<br />
PP-2<br />
Sebaceous Gland Carcinoma Masquerading as a Large<br />
Molluscum Contagiosum Nodule<br />
Emerson Jay B. Molina, Jacinto U. Dy-Liacco,<br />
Jennifer Aurea S. Sarmiento<br />
Cardinal Santos Medical Center, Philippines<br />
Objective: To report a case <strong>of</strong> a lower eyelid sebaceous<br />
gland carcinoma with features resembling a large molluscum<br />
contagiosum nodule.<br />
Methods: This is a case report.<br />
Results: A 70-year old Filipino male presented with an enlarging<br />
mass in the left lower eyelid. The lesion was noted 1 year prior<br />
to consultation to a private ophthalmologist in Cardinal Santos<br />
Medical Center. He had previously undergone incision and<br />
curettage <strong>of</strong> the lesion three times but with rapid recurrence and<br />
hence was referred to one <strong>of</strong> the authors. External exam on the<br />
right eye was unremarkable. Best corrected vision for both eyes<br />
is 20/25. There is a grade 2 nuclear cataract on both eyes, with<br />
the rest <strong>of</strong> the anterior segment findings unremarkable. He had<br />
a 1.0 x 0.9 x 0.4 cm firm, non-tender, non-movable and wellcircumscribed<br />
pearly-white nodule with central umbilication on<br />
the left lower lid encroaching the margin. The initial impression<br />
was molluscum contagiosum nodule. Patient underwent excision<br />
biopsy. However, the histopathologic diagnosis was sebaceous<br />
carcinoma with resection margins free <strong>of</strong> tumor. The patient is<br />
currently under observation and no recurrence so far has been<br />
noted.<br />
Conclusion: Sebaceous gland carcinoma is a relatively rare but<br />
potentially lethal malignancy <strong>of</strong> the eyelid. Clinical presentation<br />
may vary and it may demonstrate atypical features which could<br />
be confused with molluscum contagiosum nodule, a benign<br />
condition.<br />
Key Words: Sebaceous gland carcinoma, Molluscum<br />
contagiosum nodule<br />
PP-3<br />
Poster Presentations<br />
Effect <strong>of</strong> Topical Anesthetic in Pupillary Dilation in Filipino Eyes<br />
Joyce Ann L. Lo, Richard Raymund L. Nepomuceno<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
Objective: This study aims to determine if topical anesthetic<br />
hastens pupillary dilation in Filipino eyes.<br />
Methods: This is a prospective single blinded clinical trial.<br />
Thirty healthy subjects (60 eyes) ages 18 to 40 years old were<br />
recruited in the study. Pre-treatment photographs <strong>of</strong> both eyes<br />
were taken at the start <strong>of</strong> each part <strong>of</strong> the study. In the first part,<br />
a drop <strong>of</strong> topical proparacaine was instilled into both eyes and<br />
then the left eye was instilled with a drop <strong>of</strong> 0.5% tropicamide +<br />
0.5% phenylephrine 3 minutes after. In the second part, a drop<br />
<strong>of</strong> balanced salt solution was instilled to the right eye then a drop<br />
<strong>of</strong> 0.5% tropicamide + 0.5% phenylephrine 3 minutes after. The<br />
left eye was instilled with a drop <strong>of</strong> topical proparacaine then a<br />
drop <strong>of</strong> 0.5% tropicamide + 0.5% phenylephrine 3 minutes after.<br />
Photographs were taken <strong>of</strong> both eyes until 30 minutes. Horizontal<br />
pupil diameter was measured using Scion Image S<strong>of</strong>tware.<br />
Measurements were then analyzed using Pearson Correlation<br />
Coefficient and Paired Sample T-test.<br />
Results: Cross reactivity between the two eyes was analyzed<br />
using Pearson Correlation Coefficient. Analysis showed that<br />
there is a significant difference between both eyes horizontal<br />
pupil diameter even before treatment was given (p=0.794,<br />
99% confidence interval). There was also an increase in the<br />
measurement <strong>of</strong> the right eye (topical proparacaine only) as the<br />
measurement <strong>of</strong> the left eye (topical proparacaine and dilating<br />
28
Poster Presentations<br />
agent) increased at 5 minutes. Conversely, there was a decrease<br />
in the measurement <strong>of</strong> the right eye as the measurement in the left<br />
eye decreased (p=0.734, 99% confidence interval). Correlation<br />
became non-significant between eyes from 10 to 30 minutes<br />
(p=0.121 ± 0.353, 99% confidence interval). Comparison <strong>of</strong> the<br />
right eye given a drop <strong>of</strong> balanced salt solution then a drop <strong>of</strong><br />
0.5% tropicamide + 0.5% phenylephrine 3 minutes after and the<br />
left eye given a drop <strong>of</strong> topical proparacaine then a drop <strong>of</strong> 0.5%<br />
tropicamide + 0.5% phenylephrine 3 minutes after was analyzed<br />
using Paired Sample T-test. It showed significant difference at 5<br />
minutes measurement (p=0.041). However, correlation was nonsignificant<br />
at 10 to 30 minutes measurement (p=0.225 ± 0.901).<br />
Conclusion: Topical anesthetic did not hasten the dilation <strong>of</strong><br />
Filipino eyes.<br />
Key Words: Tropicamide, Phenylephrine<br />
PP-4<br />
A Case <strong>of</strong> Cogan’s Syndrome in the Philippines<br />
Ann Krystine C. Balmaceda, Jessica Marie R. Abaño,<br />
Rene Louie C. Gutierrez<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
Objective: This paper aims to present one <strong>of</strong> the first, if not the<br />
first, reported case <strong>of</strong> Cogan’s syndrome in the Philippines.<br />
Methods: This paper is presented as a case report.<br />
Results: Cogan’s Syndrome is an inflammatory disease with<br />
a possible autoimmune etiology. It usually presents with<br />
non-syphilitic interstitial keratitis with Meniere’s disease-like<br />
symptoms such as vertigo and progressive hearing loss. Two<br />
thirds <strong>of</strong> cases present with systemic symptoms involving the<br />
cardiovascular, musculoskeletal, neurological, gastrointestinal<br />
and mucocutaneous systems. A third <strong>of</strong> cases present with<br />
vasculitis. At present, there is no proven effective therapy for<br />
this condition. The disease is mainly managed with high dose<br />
corticosteroids. This is a case <strong>of</strong> a 37 year old male with a history<br />
<strong>of</strong> cough and colds that spontaneously resolved, followed by<br />
progressive hearing loss, loss <strong>of</strong> balance, dizziness, an enlarging<br />
whitish opacity on both eyes with accompanying eye pain, foreign<br />
body sensation and blurring <strong>of</strong> vision. He later presented with<br />
cardiovascular symptoms and vasculitis. Physical examination<br />
revealed bilateral corneal infiltrates with vascularization and<br />
ghost vessels, bilateral loss <strong>of</strong> gross hearing, bibasal crackles<br />
and systolic murmurs on the 2nd and 5th ICS. The patient was<br />
treated with cardiac medications, prednisolone acetate eyedrops<br />
and oral prednisone 40mg per day.<br />
Conclusion: High dose steroid therapy was not done in the<br />
patient. Future cases may benefit from a more aggressive<br />
treatment <strong>of</strong> high dose corticosteroids or steroid-sparing<br />
therapeutics such as TNF-alpha inhibitors.<br />
Key Words: Cogan’s syndrome, interstitial keratitis, corneal<br />
opacities, paracentral corneal infiltrates.<br />
29<br />
PP-5<br />
A Case <strong>of</strong> Cogan Syndrome<br />
Jose Mari G. Sagmit, Jacinto S. Bautista, Jr., Noel Castillo<br />
Hospital <strong>of</strong> the Infant Jesus, Philippines<br />
Objective: To describe the course <strong>of</strong> a patient diagnosed with<br />
Cogan syndrome.<br />
Methods: This is a retrospective, non-comparative case report <strong>of</strong><br />
a patient who was diagnosed with Cogan syndrome.<br />
Result: A 29 year old male deaf came in due to bilateral coneal<br />
opacity. Visual acuity was 20/50 on both eye. Slitlamp examination<br />
showed peripheral stromal opacities on both eyes. Further eye<br />
examination showed normal findings.<br />
Conclusion: Cogan syndrome is a disease which presents with<br />
blurring secondary to coneal dystrophy accompanied by bilateral<br />
hearing loss<br />
Key Words: cogan, cogan syndrome, case <strong>of</strong> cogan, a case <strong>of</strong><br />
cogan syndrome<br />
PP-6<br />
Prevalence <strong>of</strong> Dry Eye Syndrome and Diabetic Retinopathy<br />
in Type 2 Diabetes in the Hospital <strong>of</strong> the Infant Jesus<br />
Ophthalmology Outpatient Department<br />
Jamil Laurence R. So-Reyes, Jacinto S. Bautista, Jr.<br />
Hospital <strong>of</strong> the Infant Jesus, Philippines<br />
Objective: This study is performed to evaluate the prevalence <strong>of</strong><br />
dry eye syndrome in type 2 diabetics seen at the Hospital <strong>of</strong> the<br />
Infant Jesus Ophthalmology OPD. To have an evaluation using<br />
our local setting and using the Filipino population.<br />
Methods: We evaluated 102 type 2 diabetic patients referred<br />
to the Hospital <strong>of</strong> Infant Jesus Department <strong>of</strong> Ophthalmology<br />
from January <strong>2012</strong> to June <strong>2012</strong>. All subjects were given<br />
questionnaires regarding other diseases, drugs taken orally or<br />
other eyedrops and previous eye surgeries both recent and past.<br />
Dry eye syndrome was assessed with tear break up time tests<br />
and Schirmer. To determine whether Diabetic retinopathy was<br />
present, fluorescein angiography were done and evaluated by<br />
our retina consultant.<br />
Results: 58 patients (57%) out <strong>of</strong> the 102 type 2 diabetic patients<br />
suffer from dry eye syndrome based on tear break up time and<br />
Schirmer’s test. Dry eye syndrome was more frequently seen in<br />
patients with diabetic retinopathy 82 patients (80%). 24 patients<br />
with mild non proliferative diabetic retinopathy, 22 patients with<br />
moderate non proliferative diabetic retinopathy, 16 patients with<br />
severe non proliferative diabetic retinopathy, and 18 patients<br />
with proliferative diabetic retinopathy. There were significant<br />
relationship between age, sex and duration <strong>of</strong> diabetes and<br />
diabetic retinopathy.<br />
Conclusion: In our local setting using the Filipino population,<br />
prevalence <strong>of</strong> dry eye syndrome among type 2 diabetics was
57%. There is a strong association between dry eye syndrome<br />
and diabetes. Therefore this study strongly suggest dry eye<br />
screening in type 2 diabetic patients to address their risk for dry<br />
eye complications.<br />
Key Words: prevalence, dry eye syndrome, type 2 diabetes<br />
Glaucoma<br />
PP-7<br />
Axenfeld -Rieger Syndrome: Case Report<br />
Reggie R. Revilla, Ian Benjamin T. Hizon<br />
University <strong>of</strong> the East Ramon Magsaysay Memorial Medical<br />
Hospital, Philippines<br />
To report the case <strong>of</strong> a patient who was previously diagnosed<br />
with Congenital Glaucoma. Patient also has buphthalmos and<br />
had underwent enucleation <strong>of</strong> the right eye.<br />
Objective: A case <strong>of</strong> 43 year old female patient, who came in<br />
due to blurring <strong>of</strong> vision <strong>of</strong> the left eye with associated pain <strong>of</strong> 3<br />
days duration. Patient underwent enucleation <strong>of</strong> the right eye at<br />
age 5 and was lost to follow-up since then. Thirteen years ago,<br />
patient began to experience blurring <strong>of</strong> vision <strong>of</strong> the left eye.<br />
Patient sought consult after 6 years and was advised to undergo<br />
filter surgery. She refused and was subsequently lost to followup<br />
again. Two months prior to admission, patient was seen at<br />
the UERMMMCI Outpatient Department and was diagnosed with<br />
Congenital Glaucoma, OS.<br />
Results: Patient was non-compliant with the prescribed<br />
medications resulting to elevated IOP <strong>of</strong> 54mmHg and was<br />
admitted. Based on history and further examination, she was<br />
found to have Axenfeld-Rieger Syndrome.<br />
Conclusion: This presentation aims to illustrate a rare case<br />
<strong>of</strong> Axenfeld-Rieger syndrome. A 43 year old female patient<br />
seen at the Emergency room due to painful blurring <strong>of</strong> vision<br />
<strong>of</strong> a few hours duration. Elevated IOP was managed. Careful<br />
review <strong>of</strong> patient’s history and thorough physical examination<br />
reveal buphthalmos, posterior embryotoxon and other findings<br />
pointing to Axenfeld-Rieger Syndrome. The patient subsequently<br />
underwent trans-scleral photocoagulation and resolution <strong>of</strong> eye<br />
pain was observed. This presentation is intended to highlight the<br />
importance <strong>of</strong> thorough history taking and physical examination<br />
for the recognition <strong>of</strong> patients experiencing this condition<br />
Key Words: axenfeld-rieger syndrome, congenital glaucoma,<br />
posterior embryotoxon, buphthalmos<br />
PP-8<br />
Poster Presentations<br />
Treatment Option for the Management <strong>of</strong><br />
Neovascular Glaucoma<br />
Mark Gil J. Marasigan, Ronaldo Jarin<br />
Quirino Memorial Medical Center, Philippines<br />
Objective: 1. To describe a treatment option for the management<br />
<strong>of</strong> neovascular glaucoma. 2. To evaluate the recommended<br />
treatment option for the management <strong>of</strong> neovascular glaucoma.<br />
3. To describe the visual acuity, intraocular pressure, and the<br />
presence <strong>of</strong> iris and/or angle neovascularization as the primary<br />
outcome measure. 4. To recommend this treatment option for<br />
patients with neovascular glaucoma.<br />
Methods: Observational Case Series. Quirino Memorial Medical<br />
Center. All patients diagnosed with neovascular glaucoma are<br />
identified from January <strong>2012</strong> to September <strong>2012</strong>. Standard<br />
ophthalmic data were recorded in each case including age, sex,<br />
visual acuity, intraocular pressure (IOP), co-morbid conditions<br />
such as hypertension and diabetes mellitus and laterality <strong>of</strong><br />
affected eye at the time <strong>of</strong> first consult. Initial treatment option is<br />
then applied and the outcome evaluated in terms <strong>of</strong> visual acuity,<br />
control <strong>of</strong> intraocular pressure, and the presence <strong>of</strong> iris and/or<br />
angle neovascularization.<br />
Results: 16 eyes <strong>of</strong> 16 patients were seen with neovascular<br />
glaucoma during the period <strong>of</strong> January <strong>2012</strong>-September <strong>2012</strong>.<br />
The study group included 7 males and 9 females aged 30 to 64<br />
years. Out <strong>of</strong> the 16 cases, 9 had proliferative diabetic retinopathy,<br />
and 7 were secondary to ischemic central retinal vein occlusion,<br />
<strong>of</strong> whom 1 had undergone vitrectomy for vitreous hemorrhage.<br />
All patients were followed for at least 6 months. 5 patients<br />
improved their visual acuity from hand movement and 20/400 to<br />
20/200 and 20/100 respectively. Iris and anterior chamber angle<br />
neovascularisation receded in all eyes after 1 to 3 injections <strong>of</strong><br />
Bevacizumab (Avastin) prior to trabeculectomy and panretinal<br />
photocoagulation. The intraocular pressure normalized in 12<br />
eyes during the ff up period while 4 eyes needed anti-glaucoma<br />
medications for further IOP lowering.<br />
Conclusion: Several treatment options are available for the<br />
management <strong>of</strong> neovascular glaucoma. In our setting, we have<br />
applied a treatment option that will be suitable for our patient’s<br />
pr<strong>of</strong>ile especially those who are not capable <strong>of</strong> acquiring a valve<br />
implant for IOP lowering. This treatment option have given a good<br />
outcome in terms <strong>of</strong> its IOP control after trabeculectomy and iris/<br />
angle neovascularization regression after intravitreal injection<br />
<strong>of</strong> Bevacizumab (Avastin). Visual acuity, in the other hand, may<br />
have improved owing to the lowering <strong>of</strong> the intraocular pressure<br />
and reduction in corneal edema.<br />
Key Words: Neovascular Glaucoma, Anterior chamber<br />
angle neovascularisation, Intravitreal bevacizumab, Iris<br />
neovascularisation<br />
30
Poster Presentations<br />
Lens and Cataract Surgery<br />
PP-9<br />
Comparison <strong>of</strong> Axial Length Measurements Taken by<br />
Partial Optical Coherence Interferometry (IOL Master®) and<br />
Immersion Scan<br />
Jessica De Leon, Richard Raymund L. Nepomuceno<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
Objective: The importance <strong>of</strong> accurate axial length measurements<br />
in cataract and refractive surgeries cannot be overemphasized<br />
because a difference <strong>of</strong> as little as 0.3mm from true value <strong>of</strong> AXL<br />
will result in 1 diopter error in the IOL power. This study aims<br />
to compare the axial length measurements taken by the IOL<br />
Master and Pacscan Immersion Biometry, especially in short<br />
and long eyeballs (AXL 25mm respectively). If this<br />
study will show a significant difference between the two, then we<br />
can determine which eyeball size do the two techniques vary. If<br />
this study will not show a significant difference between the two<br />
machines, then this can reinforce our confidence in using the<br />
immersion A scan for AXL measurements.<br />
Methods: This is a cross sectional study comparing axial length<br />
measurements taken by IOL master and Pacscan Immersion<br />
biometry. Subjects include patients undergoing biometry at the<br />
St. Luke’s Medical Center QC from December 2011 to June <strong>2012</strong>.<br />
Axial lengths <strong>of</strong> 117 eyes were measured and were categorized<br />
into Group A (short eyeballs), Group B (medium-sized eyeballs)<br />
and Group C (long eyeballs). Two mean axial lengths will be<br />
obtained per eye (IOL master and immersion biometry), and<br />
comparison between the two measurements are done. A p value<br />
< 0.05 is considered significant.<br />
Results: statistical analysis <strong>of</strong> the 117 eyes showed no significant<br />
difference between AXL measured by IOL Master and Immersion<br />
biometry. This is when all the eyes are considered as a whole.<br />
Conclusion: there is no significant difference between AXL<br />
measured by the IOL Master and Immersion biometry if eyes with<br />
short, medium and long AXL are taken as a whole.<br />
Key Words: Immersion biometry, Optical coherence biometry,<br />
optical coherence vs immersion biometry, axial length, Pacscan,<br />
IOL Master<br />
PP-10<br />
Effect <strong>of</strong> Heat from Gaseous Sterilization on Antimicrobial<br />
Efficacy <strong>of</strong> Moxifloxacin 0.5% Eye Drops<br />
Mark Christian R. Rivera<br />
University <strong>of</strong> Santo Tomas Hospital, Philippines<br />
Objective: To compare the antimicrobial efficacy <strong>of</strong> a newly<br />
opened Moxifloxacin 0.5% eye drops with a Moxifloxacin 0.5% eye<br />
drops exposed to heat from gaseous sterilization by measuring<br />
zones <strong>of</strong> inhibition using the Kirby-Bauer disc diffusion test.<br />
Methods: This is an experimental study where in vitro inoculation<br />
<strong>of</strong> test organisms were used and zones <strong>of</strong> inhibition to both newly<br />
31<br />
opened and heat-exposed Moxifloxacin 0.5% eye drops were<br />
determined after 24 hours <strong>of</strong> incubation at 37oC. The zone sizes<br />
in millimeters were compared with each other using the two-tailed<br />
T-test to determine if significant differences were observed.<br />
Results: The zones <strong>of</strong> inhibition using the Kirby Bauer<br />
disc diffusion test to both newly opened and heat-exposed<br />
Moxifloxacin 0.5% eye drops showed no significant difference in<br />
all test organisms using the two-tailed T-test.<br />
Conclusion: Moxifloxacin 0.5% eye drops exposed to heat from<br />
gaseous sterilization showed non-inferior antimicrobial efficacy<br />
compared to a newly opened 0.5% Moxifloxacin eye drops in<br />
vitro. Re-sterilization <strong>of</strong> the eye drops bottle with its content for<br />
multiple intracameral use may be an option for cost-effectiveness.<br />
However its safety pr<strong>of</strong>ile is undetermined.<br />
Key Words: intracameral prophylaxis, gas sterilization<br />
PP-11<br />
Comparison <strong>of</strong> the Sealing Ability Between the Wong Incision<br />
and Standard Stromal Hydration <strong>of</strong> Clear Cornea Incisions in<br />
Phacoemulsification Surgery: An Animal Eye Study<br />
Raymond Nelson C. Regalado, Ruben Lim Bon Siong,<br />
Jay Marianito S. Vicencio, Lee Verzosa<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
Objective: The primary objective is to determine the efficacy<br />
<strong>of</strong> the Wong incision in providing CCI wound seal against influx<br />
<strong>of</strong> ocular surface fluid compared to the standard lateral stromal<br />
wall hydration using pig’s eyes. Secondary objectives include:<br />
to document the presence <strong>of</strong> refluxed ocular surface fluid in the<br />
corneal incision tract by microscopic examination <strong>of</strong> histologic<br />
corneal sample, to assess the magnitude <strong>of</strong> ocular surface fluid<br />
influx in the anterior chamber <strong>of</strong> the using trypan blue dye and<br />
UV spectrophotometry, and to assess wound leakage <strong>of</strong> the main<br />
incision after hydration.<br />
Methods: A total <strong>of</strong> 10 pig’s eyes were used. Half were placed<br />
in the stromal wall hydration group (control) and half in the<br />
Wong incision group (experimental). On a globe holder, a side<br />
port was made and viscoelastic placed in the AC. The main<br />
incision was made 180 degrees away; in the experimental group,<br />
a Wong incision was made prior. Phacoemulsification with IOL<br />
implantation was simulated. The main incision was sealed. An AC<br />
maintainer was placed. A sample from the AC was taken and sent<br />
for analysis. Trypan blue was then dripped over the main incision.<br />
At this time, another sample was taken from the AC and sent for<br />
analysis. The whole eyeball was sent for histopathology.<br />
Results: All samples showed no significant change in<br />
spectrophotometric absorbance, indicating that in both, no<br />
significant amount <strong>of</strong> trypan blue was able to enter the AC.<br />
Histological samples failed to show trypan blue staining in<br />
both incision tracts, suggesting that no passage <strong>of</strong> trypan blue<br />
occurred. Video documentation showed significant wound<br />
leakage in the control group and none in the experimental.<br />
Conclusion: The Wong incision provided no significant benefit<br />
compared to stromal wall hydration in preventing fluid influx after<br />
cataract surgery simulation. The Wong incision, however, showed
a more stable wound seal against wound leakage.<br />
Key Words: Wong incision, Superior stromal pocket, Sutureless<br />
clear corneal incision, Endophthalmitis<br />
PP-12<br />
Evaluation <strong>of</strong> the Effectiveness <strong>of</strong> the Angled Sinskey Hook<br />
for Vertical Quick-Chop Nucleotomy in Phacoemulsification<br />
Lenard Paul Concepcion, Antonio Say, Alex Sua<br />
University <strong>of</strong> Santo Tomas Hospital, Philippines<br />
Objective: To evaluate the effectiveness <strong>of</strong> the unmodified angled<br />
Sinskey hook when used as a phaco chopper in performing the<br />
vertical quick-chop nucleotomy technique in phacoemulsification.<br />
Methods: This is a prospective randomized study involving 18<br />
eyes <strong>of</strong> 18 consecutive patients randomly assigned to undergo<br />
vertical quick-chop nucleotomy in phacoemulsification using<br />
the angled Sinskey hook, or the Chang vertical chopper for<br />
vertical chop nucleotomy. Vertical quick-chop nucleotomy in<br />
phacoemulsification was performed by 1 surgeon (L.P.A.C, a<br />
SENIOR RESIDENT IN TRAINING) using the INFINITIR phaco<br />
machine. The parameters, the vertical chop success, number<br />
<strong>of</strong> vertical chop attempts, and Effective Phaco Time (E.P.T.)<br />
/ Cumulative Dissipated Energy (C.D.E.), measured were in<br />
relation to nuclear density. The chi-square test, independentsamples<br />
t test, and analysis <strong>of</strong> covariance were used to compare<br />
the groups for statistical significance.<br />
Results: The chi-square showed that the difference between<br />
overall chop successes <strong>of</strong> the 2 groups was not statistically<br />
significant (P value: 0.527). The independent-samples t test<br />
showed that there is no significant difference between the 2<br />
groups in terms <strong>of</strong> the number <strong>of</strong> vertical quick-chop attempts<br />
(P value: 0.653) and EPT/CDE (P value: 0.859). Analysis <strong>of</strong><br />
covariance comparing the relationship <strong>of</strong> nuclear density to chop<br />
successes <strong>of</strong> the 2 groups showed that the difference between the<br />
numbers <strong>of</strong> chop attempts (P value: 0.547) was not statistically<br />
significant. Analysis <strong>of</strong> covariance comparing the relationship <strong>of</strong><br />
nuclear density to the EPT/CDE <strong>of</strong> the 2 groups showed that the<br />
difference between the EPT/CDE (P value: 0.666) <strong>of</strong> the 2 groups<br />
was not statistically significant.<br />
Conclusion: The angled Sinskey hook, with proper surgical<br />
competency in vertical quick-chop, may be used as an effective<br />
primary chopping instrument for vertical quick-chop nucleotomy<br />
in phacoemulsification.<br />
Key Words: Nucleotomy, Nagahara horizontal chop, Sinskey<br />
hook, phacoemulsification, Vertical quick-chop, Nucleotomy,<br />
Sinskey hook, phacoemulsification, Nagahara horizontal chop<br />
Neuro-ophthalmology<br />
PP-13<br />
Ocular Myasthenia Gravis with Probable Thymoma in a<br />
Prepubertal Male<br />
Jennifer Aurea S. Sarmiento, Karen B. Reyes<br />
Cardinal Santos Medical Center, Philippines<br />
Objective: To report a case <strong>of</strong> a prepubertal male with ocular<br />
myasthenia gravis and probable thymoma.<br />
Methods: This is a case report.<br />
Results: A 10-year old Filipino male presented with a one-month<br />
history <strong>of</strong> drooping <strong>of</strong> the left eyelid. Eyelids are apparently well<br />
upon waking up, but droop towards the end <strong>of</strong> the day. There<br />
were no noted diplopia, blurring <strong>of</strong> vision and eye pain. No history<br />
<strong>of</strong> trauma or any previous eye insults. The patient denied difficulty<br />
in swallowing or breathing. He was born full-term via normal<br />
delivery born to a primi-mother. On examination, visual acuity<br />
was 20/20 in both eyes. Ductions and versions were normal, with<br />
no deviation. Left ptosis was noted. The interpalpebral fissure<br />
measured 9mm on the right and 4 mm on the left. Margin Reflex<br />
Distance (MRD) on the right eye was 4/5 while it was 0/4 mm<br />
on the left. The levator functions were good. There were no lid<br />
swelling, lagophthalmos, and proptosis. Cogan’s lid twitch sign and<br />
Gorlick’s test were positive. Ice pack test showed improvement<br />
<strong>of</strong> ptosis. Single Fiber electromyogram (EMG) results support<br />
the diagnosis <strong>of</strong> ocular myasthenia gravis. Chest computed<br />
tomography confirmed the presence <strong>of</strong> an anterior mediastinal<br />
mass, probably thymoma. The patient was co-managed with<br />
Pediatric service and was started on Pyridostigmine 60mg/tab,<br />
which was gradually increased to 27.8mg/pptab. At 10-month<br />
follow-up, patient showed improvement with pyridostigmine.<br />
Conclusion: We present a rare case <strong>of</strong> ocular myasthenia<br />
gravis with probable thymoma in a prepubertal male. Ocular<br />
manifestations have stabilized with Pyridostigmine alone.<br />
Key Words: Ocular Myasthenia Gravis, Thymoma, Pyridostigmine<br />
PP-14<br />
Poster Presentations<br />
A Review <strong>of</strong> Prevalence <strong>of</strong> Neuro-Ophthalmic Disorders in a<br />
Government Tertiary Hospital in Quezon City, Philippines -<br />
A 4 years Study<br />
Ryan R. Bacani<br />
DOH Eye Center East Avenue Medical Center, Philippines<br />
Objective: Determine the pattern, co morbidities and prevalence<br />
<strong>of</strong> Neuro-Ophthalmologic cases in a government tertiary hospital<br />
in the Philippines.<br />
Methods: This is a retrospective study <strong>of</strong> all neuro-ophthalmologic<br />
cases within 4 years - period (January 2008 to December 2011) in<br />
the DOH Eye Center East Avenue Medical Center, East Avenue,<br />
Quezon City, Philippines.<br />
Results: There were a total <strong>of</strong> 460 neuro-ophthalmic cases<br />
seen during the 4 years study period. With 2011 has the highest<br />
number <strong>of</strong> cases. The estimated prevalence rate <strong>of</strong> neuroophthalmic<br />
cases was noted by having the total number <strong>of</strong><br />
General ophthalmology consult as denominator per year. Overall,<br />
Vision-related disorders were the most frequently seen, followed<br />
by ocular motility related diseases. Traumatic related disorders<br />
(n = 85 cases, 18.48%) were the most commonly encountered<br />
among neuro-ophthalmic consults. Other primary causes include<br />
Optic Neuritis (11.78%), and Ethambutol toxicity optic neuropathy<br />
(7.83%). Other etiologies noted for the vision related disorders<br />
32
are ischemia and compressive disorders. For specific neuroophthalmic<br />
entities, palsies <strong>of</strong> the abducens nerve (9.13%),<br />
oculomotor nerve (6.3%), and multiple cranial nerve palsy<br />
(4.35%) were observed with most number <strong>of</strong> cases.<br />
Conclusion: During the 4 years retrospective study, traumatic<br />
related disorder was noted to be the leading cause <strong>of</strong> neuroophthalmology<br />
diseases in our setting. The burden <strong>of</strong> this disorder<br />
should be addressed in a multi center approach. Risk factors<br />
and other co- morbdities that affects other Neuro-ophthalmology<br />
etiologies are to be properly determined and resolve.<br />
Key Words: Neuro-ophthalmic disorders, prevalence,<br />
retrospective study, DOH Eye Center East Avenue Medical<br />
Center<br />
PP-15<br />
Poster Presentations<br />
Ptosis and Ophthalmoplegia in a 56 Year Old Post Corneal<br />
Transplant Patient: A Case Report<br />
Kristine Belen Pascua, Leonides Karlo C. Melendres, III<br />
DOH Eye Center- East Avenue Medical Center, Philippines<br />
Objective: To present a case <strong>of</strong> an early onset, progressive<br />
ptosis and ophthalmoplegia who underwent lid surgery and<br />
presented with lagaophthalmos, chronic exposure keratopathy<br />
and ruptured corneal ulcer<br />
Case: This is a case <strong>of</strong> a 56 year old female who presented with<br />
ptosis and ophthalmoplegia.<br />
Methods: The patient presented with progressive drooping <strong>of</strong><br />
both upper lids with limited extraocular muscle movement 30<br />
years prior to consult. Due to persistence <strong>of</strong> symptoms patient<br />
underwent a lid surgery. Following lid surgery there was note <strong>of</strong><br />
lagophthalmos and exposure keratopathy.<br />
Results: Patient came in to our institution with a ruptured<br />
corneal ulcer secondary to Central Microbial Keratitis and chronic<br />
exposure keratitis <strong>of</strong> the right eye necessitating penetrating<br />
keratoplasty.<br />
Conclusion: Patients with chronic progressive external<br />
ophthalmoplegia have a limited ability to protect the eye from<br />
chronic exposure leading to corneal damage. Lagophthalmos<br />
in the presence <strong>of</strong> extraocular movement dysfunction requires<br />
preventive measures to avoid exposure keratopathy. Also,<br />
meticulous history taking and ophthalmologic exam before the lid<br />
surgery should have prevented the sequalae <strong>of</strong> chronic exposure<br />
keratopathy.<br />
Key Words: lagophthalmos, mitochondrial myopathy, exposure<br />
keratopathy, ptosis, chronic progressive external ophthalmoplegia<br />
33<br />
PP-16<br />
Unilateral Optic Nerve Atrophy in a Child with Schizencephaly:<br />
A Case Report<br />
Denver K. Ching, Leonides Karlo Melendres, III<br />
DOH Eye Center East Avenue Medical Center, Philippines<br />
Objective: To present a case <strong>of</strong> unilateral optic atrophy in a child<br />
with schizencephaly.<br />
Method: This is a case report<br />
Result: An 8 year old female presented with a month history<br />
<strong>of</strong> progressive blurring <strong>of</strong> vision on the left eye and slurring <strong>of</strong><br />
speech. Left sided body weakness was already noted since 1<br />
year <strong>of</strong> age. Visual acuity <strong>of</strong> the affected eye on initial consult<br />
was counting fingers at 2 feet. Funduscopic exam showed left<br />
optic nerve pallor while the rest <strong>of</strong> ophthalmologic examination<br />
findings were unremarkable. Cranial MRI revealed open lip<br />
schizencephaly involving the right frontal lobe with evidence <strong>of</strong><br />
polymicrogyria. The corpus callosum and septum pellucidum are<br />
intact. Optical coherence tomography showed severe generalized<br />
rim thinning <strong>of</strong> the left optic nerve.<br />
Conclusion: Neuroimaging studies and detailed clinical<br />
examination are equally important for the diagnosis and<br />
appropriate management <strong>of</strong> schizencephaly presenting both with<br />
neurologic and visual symptoms.<br />
Key Words: schizencephaly, optic nerve atrophy, polymicrogyria<br />
PP-17<br />
Third Nerve Palsy Probably Ischemic: A Non Resolving Palsy<br />
in a 58 Year Old Male<br />
Abegaile O. Bartolome, Erwin D. Palisoc, Emilio Macias, III,<br />
Evelyn S. Morabe<br />
Jose R. Reyes Memorial Medical Center, Philippines<br />
Objective: To present a case <strong>of</strong> ischemic third nerve palsy with<br />
pupillary involvement and persistent course<br />
Method: Case Report<br />
Results: A 58 year old hypertensive male, smoker was seen<br />
at the OPD JRRMMC 2 years ago with complaint <strong>of</strong> drooping<br />
<strong>of</strong> right eyelid. Impression then was complete third nerve palsy<br />
with pupillary involvement. CT Scan revealed: Atherosclerotic<br />
bilateral internal carotid and vertebral arteries; Unremarkable<br />
plain and contrast enhanced orbital CT scan. He was referred to<br />
Neurology Service but was lost to follow-up until 4 months ago<br />
when he came back still with drooping <strong>of</strong> right eyelid, associated<br />
with blurring <strong>of</strong> vision on both eyes. On examination, visual acuity<br />
on the right is 20/63 improved to 20/40 and on the left is 20/63<br />
improved to 20/25. Right pupil is 3-4 mm sluggishly reactive to<br />
light and left pupil is 2-3 mm briskly reactive to light. The right<br />
eyelid was ptotic. The right eye was deviated outward and there<br />
was limitation <strong>of</strong> elevation, depression, and adduction. The lenses<br />
were cataractous. The rest <strong>of</strong> the eye findings were unremarkable.<br />
Neurological examination was likewise unremarkable except
for Cranial nerve III palsy. Magnetic Resonance Imaging with<br />
angiography showed: Mild chronic small vessel ischemic changes<br />
involving the fronto-parietal white matter bilaterally. Small<br />
abnormal signal in the left subinsular region which is non specific,<br />
could be due to focus <strong>of</strong> infarct, chronic small vessels change or<br />
venous angioma.<br />
Conclusion: Ischemic third nerve palsy <strong>of</strong>ten spares the pupil<br />
and is usually self limiting. In this 58 year old hypertensive male,<br />
the pupil was involved, the findings on MR angiography showed<br />
microvascular injury with no aneurysm, and the condition has<br />
persisted for 2 years from onset. The non resolution <strong>of</strong> the<br />
findings may be attributed to poor control <strong>of</strong> the hypertension,<br />
which caused permanent microvascular injury.<br />
Key Words: third nerve palsy, ischemia, neuro-ophthalmology<br />
PP-18<br />
Post Operative Abducens Nerve Palsy<br />
Caesar Percival F. Sunio, Karen B. Reyes<br />
Ospital ng Makati, Philippines<br />
Objectives: To report a case <strong>of</strong> unilateral abducens nerve palsy<br />
in a post repeat mastoidectomy patient.<br />
Methods: This is a case report.<br />
Results: This is a case report <strong>of</strong> a 4 y/o female with the complaint<br />
<strong>of</strong> abducens nerve palsy after undergoing repeat mastoidectomy.<br />
The patient had a history <strong>of</strong> Bell’s palsy and chronic otitis media.<br />
Ophthalmologic and neurologic examination revealed a left<br />
facial nerve paralysis and abducens nerve palsy. Orbital CT<br />
and Temporal CT scan was done which showed a s<strong>of</strong>t tissue<br />
mass involving the pons, clivus and temporal petrous bone.<br />
Histopathology test done during the operation showed a s<strong>of</strong>t tissue<br />
sarcoma, further histoimmunological test for sarcomeric actin and<br />
desmin were both positive, indicative <strong>of</strong> a Rhabdomyosarcoma.<br />
Patient was referred to the Pediatric Oncology service for<br />
chemotherapy with cyclophosphamide and vincristine.<br />
Conclusion: The presence <strong>of</strong> sudden abducens nerve palsy in<br />
a pediatric patient requires a thorough history and neurologic<br />
examination, this in turn, would aid in the proper diagnostic<br />
approach to help determine the etiology <strong>of</strong> the disease, especially<br />
in life-threatening cases.<br />
Key Words: Abducens nerve palsy, Facial nerve palsy,<br />
Rhabdomyosarcoma, Chemotherapy<br />
PP-19<br />
Dengue Fever with Optic Neuropathy<br />
Pius Jonas F. Ocampo, Buenjim Mariano<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
Objective: The purpose <strong>of</strong> this study is to report a case <strong>of</strong> optic<br />
neuropathy associated with dengue fever.<br />
Method: The study design is a case report. The patient is an 18<br />
year old male admitted because <strong>of</strong> dengue fever who complained<br />
<strong>of</strong> blurring <strong>of</strong> vision <strong>of</strong> both eyes. Visual acuity was 20/20 on the<br />
right and 20/400 on the left. Optic nerve examination showed<br />
no edema. Fluorescein angiography and optical coherence<br />
tomography <strong>of</strong> the macula were done and revealed normal<br />
results. Color vision using Ishihara chart showed 15/17 on the<br />
right and 0/17 on the left. Visual Field examination revealed<br />
central scotoma on both eyes. The patient was started on<br />
methylprednisolone 250mg/ IV every 6 hours for 3 days and was<br />
tapered slowly.<br />
Results: Improvement <strong>of</strong> visual acuity, color vision and visual<br />
fields were noted on the second day <strong>of</strong> steroid treatment<br />
Conclusions: Since severe and permanent visual loss have<br />
been reported in cases <strong>of</strong> optic neuropathy in patients with<br />
dengue fever, steroid therapy using IV methylprednisolone can<br />
be a treatment option aside from observation.<br />
Key Words: Dengue, Fever, Optic, Neuropathy<br />
PP-20<br />
Giant Cell Arteritis: A Case Report <strong>of</strong> a 77 year old Female<br />
Almira A. Manzano, Roberto Uy<br />
University <strong>of</strong> Santo Tomas Hospital, Philippines<br />
Objective: To report a patient diagnosed with Giant cell arteritis<br />
in the Philippines.<br />
Methods: This is a case report.<br />
Poster Presentations<br />
Results: A case <strong>of</strong> a 77 year old Filipino female who presented<br />
with sudden painless blurring <strong>of</strong> vision on left eye accompanied<br />
by headache, jaw claudication and body weakness. Visual acuity<br />
on the left eye was no light perception. Laboratory work-up was<br />
initially done which showed elevated erythrocyte sedimentation<br />
rate <strong>of</strong> 110, CRP <strong>of</strong> 21.06mg/L and thrombocytosis. Treatment<br />
with oral Prednisone 60mg/day was immediately initiated.<br />
Because <strong>of</strong> high index <strong>of</strong> suspicion <strong>of</strong> giant cell arteritis, biopsy <strong>of</strong><br />
the left temporal artery was done which revealed multinucleated<br />
giant cells with numerous neutrophils, lympho-plasmacytic<br />
inflammatory cell infiltrates and histiocytes concentrated in elastic<br />
laminae.<br />
Conclusion: Giant cell arteritis commonly affects elderly in<br />
Western world but not in Southeast Asia. It is usually suspected<br />
in cases <strong>of</strong> severe unilateral sudden visual loss in the elderly<br />
however, temporal artery biopsy which is the gold standard for its<br />
diagnosis is rarely done to document the disease. It is significant<br />
to diagnose it early because the second eye can be involved<br />
later in the course and less <strong>of</strong>ten it may lead to other serious<br />
complications.<br />
Key Words: temporal artery biopsy, giant cell arteritis, giant cell<br />
arteritis, temporal artery biopsy<br />
34
Poster Presentations<br />
Optics, Refraction, and Contact Lens<br />
PP-21<br />
Comparison <strong>of</strong> Visual and Refractive Outcomes Using a<br />
Microkeratome Versus Femtosecond Laser in Creating a<br />
Flap for Corneal Inlay Implantation<br />
Vincent Joseph Corpus, Robert Edward T. Ang<br />
Cardinal Santos Medical Center, Philippines<br />
Objective: To compare post-operative visual, refractive<br />
outcomes and patient satisfaction in eyes that underwent corneal<br />
inlay implantation underneath a thick flap created using either a<br />
femtosecond laser (FS) or a microkeratome (MK).<br />
Methods: This is a retrospective study <strong>of</strong> patients who underwent<br />
monocular implantation <strong>of</strong> Acufocus KAMRA ACI7000PDT inlay<br />
in the nondominant eye using either a mechanical keratome<br />
or a femtosecond laser from July 2008 to January <strong>2012</strong>. We<br />
reviewed the records <strong>of</strong> 48 patients implanted with the inlay with<br />
at least a 6-month follow-up. The main outcome measures were<br />
postoperative monocular and binocular uncorrected distance,<br />
(UDVA), intermediate (UIVA), and near (UNVA) visual acuities.<br />
Postoperative refractive errors, subjective assessment <strong>of</strong><br />
symptoms and patient satisfaction were also evaluated.<br />
Results: The mean UDVA and UIVA remained stable at 20/20<br />
or better monocularly and binocularly for both groups, while the<br />
mean monocular and binocular UNVA improved from J5 to J1 in<br />
both groups. No significant difference between preoperative and<br />
postoperative mean manifest refraction spherical equivalent was<br />
noted between the FS and MK groups. 85% <strong>of</strong> patients in the FS<br />
group and 77% in the MK group were satisfied with the procedure.<br />
In the MK group, implantation with the corneal inlay was aborted<br />
in three eyes due to inadequate flap thickness.<br />
Conclusion: Visual and refractive outcomes and patient<br />
satisfaction were similar between the two groups. Achieving<br />
the desired flap thickness was less predictable using the<br />
microkeratome as compared to the femtosecond laser. We<br />
recommend using the femtosecond laser for flap creation to avoid<br />
aborted inlay implantation.<br />
Key Words: Corneal Inlay, Presbyopia, Mechanical Keratome,<br />
Acufocus<br />
Orbit, Eyelids, Lacrimal, and Plastic<br />
PP-22<br />
Beveled Osteotomies in Lateral Orbitotomy Using a<br />
Customized Rotating Bone Saw for Orbital Neoplasms<br />
Ma. Donna D. Santiago<br />
Far Eastern University - Nicanor Reyes Memorial Foundation,<br />
Philippines<br />
Objective: To evaluate the outcome <strong>of</strong> beveled osteotomies<br />
in lateral orbitotomy using a customized rotating bone saw for<br />
orbital neoplasms. This method involves creating the bone flap in<br />
35<br />
a manner that promotes osseous union and eliminates the need<br />
for miniplate titanium hardware.<br />
Methods: This paper represents a case series (19 orbits from<br />
18 patients) <strong>of</strong> lateral orbitotomies for excision biopsy <strong>of</strong> orbital<br />
neoplasms, over a 10-year period (from September 2001 to<br />
October 2011). Preoperative and postoperative measurements<br />
were tabulated and statistically analyzed.<br />
Results: The case series demonstrated that beveled osteotomies<br />
in lateral orbitotomy are technically possible for excision biopsy <strong>of</strong><br />
all neoplasms in this study. No patient needed the use <strong>of</strong> miniplate<br />
hardware for lateral orbital wall repositioning, nor complained <strong>of</strong><br />
a palpable orbital wall deformity. Ninety-five percent (95%) <strong>of</strong><br />
cases demonstrated significant improvement in proptosis with an<br />
average Hertel exophthalmometry reduction <strong>of</strong> 3.5 mm. Evidence<br />
<strong>of</strong> osseous union was demonstrated in 5 patients who underwent<br />
postoperative computed tomography scan.<br />
Conclusion: Beveled osteotomies in lateral orbitotomy using<br />
a customized rotating bone saw is a modified technique that<br />
provides excellent access to the lateral subperiorbital, peripheral<br />
and central surgical spaces. The exposure was adequate for<br />
excision biopsy <strong>of</strong> all neoplasms in this study. The technique<br />
promotes osseous union without the use <strong>of</strong> miniplate hardware.<br />
Key Words: Osteotomy, Lateral orbitotomy, Orbital neoplasms,<br />
Excision biopsy<br />
PP-23<br />
Mixed Capillary and Cavernous Hemangioma: A Case Report<br />
Jesilyn Penny E. Lim, Ma. Donna D. Santiago<br />
Far Eastern University-Nicanor Reyes Medical Foundation<br />
Medical Center, Philippines<br />
Objective: To present a case <strong>of</strong> a 14-year old male with an orbital<br />
mass diagnosed with histopathology as Mixed Capillary and<br />
Cavernous Hemangioma.<br />
Methods: Complete ophthalmologic examination and computed<br />
tomography were done which led to a preoperative impression <strong>of</strong><br />
Cavernous Hemangioma. The patient underwent excision biopsy<br />
<strong>of</strong> the orbital mass through a medial orbitotomy.<br />
Results: A well-circumscribed ovoid mass was excised, which,<br />
histopathology revealed as a mixed capillary and cavernous<br />
hemangioma with thrombus formation. The intra-operative and<br />
post-operative courses were unremarkable. The vision on the<br />
operated eye was maintained at its preoperative level <strong>of</strong> 20/20<br />
even post-operatively. Resolution <strong>of</strong> proptosis and diplopia were<br />
also noted<br />
Conclusion: Vascular lesions <strong>of</strong> the orbit can be confusing with<br />
diagnostic imaging features that may overlap. The differentiation<br />
with this group <strong>of</strong> lesions is usually possible through correlation<br />
<strong>of</strong> characteristic imaging features with significant clinical findings.<br />
The choice <strong>of</strong> surgical intervention should consider lesion<br />
accessibility while minimizing possible complications.
Key Words: Mixed Hemangioma, Antero-medial Orbitotomy,<br />
Cavernous Hemangioma<br />
PP-24<br />
Recurrent Orbital Inflammatory Disease in a Pediatric Patient<br />
Jerica Paula D. Berdon, Ma. Donna D. Santiago<br />
Far Eastern University-Nicanor Reyes Medical Foundation<br />
Medical Center, Philippines<br />
Objective: To present a case <strong>of</strong> an 8-year old female with<br />
orbital inflammatory disease which presented as a mass on the<br />
superolateral aspect <strong>of</strong> the orbit. There was no resolution using<br />
standard steroid therapy, thus, excision biopsy was done through<br />
a lateral orbitotomy with bone flap but with recurrence three<br />
months postoperatively.<br />
Methods: Physical and diagnostic examinations led to an initial<br />
impression <strong>of</strong> orbital inflammatory disease. There was absence<br />
<strong>of</strong> resolution <strong>of</strong> orbital signs and symptoms on steroid therapy.<br />
Excision biopsy <strong>of</strong> orbital mass through a lateral orbitotomy with<br />
bone flap, with frozen section, was done.<br />
Results: Excision biopsy revealed an irregular reddish brown<br />
mass which on histopathology showed a chronic inflammatory<br />
process. Three months postoperatively, there was recurrence <strong>of</strong><br />
swelling <strong>of</strong> the left upper lid. Repeat Orbital CT scan revealed<br />
an enhancing s<strong>of</strong>t tissue mass that could be one or combination<br />
<strong>of</strong> fibrosing tissue or recurrence. Review <strong>of</strong> the histopathologic<br />
specimen was done for which the diagnosis <strong>of</strong> chronic<br />
inflammatory disease was re-affirmed. The patient was referred<br />
back to Pediatric service where steroid therapy was restarted.<br />
Orbital inflammatory signs were noted to respond favorably to<br />
steroid treatment.<br />
Conclusion: Orbital diseases may be inflammatory or<br />
non-inflammatory. Differentiating them is crucial to provide<br />
appropriate treatment for our patients. A detailed history, followed<br />
by a comprehensive physical examination and complimented<br />
by appropriate radiological evaluation is the optimal approach<br />
to arrive at the correct diagnosis. Surgical intervention should<br />
be reserved for cases <strong>of</strong> orbital inflammatory disease where an<br />
aggressive lesion or malignancy is being ruled out. The surgical<br />
approach should provide optimal exposure while minimizing<br />
perioperative morbidity.<br />
Key Words: Pseudotumor, lateral orbitotomy, chronic<br />
inflammation<br />
PP-25<br />
The Efficacy <strong>of</strong> Topical Mitomycin-C in the Prevention <strong>of</strong><br />
Recurrence <strong>of</strong> Conjunctival Squamous Cell Carcinoma in a<br />
36-year Old Male<br />
Kate Concepcion-Torio, Ma. Rachelle Katrina C. Solis<br />
Jo Anne P. Hernandez<br />
Cardinal Santos Medical Center, Philippines<br />
Objective: To report a case <strong>of</strong> conjunctival squamous cell<br />
carcinoma treated with Mitomycin C (MMC) 0.04% Post Excision<br />
for Prevention <strong>of</strong> Tumor Recurrence.<br />
Method: This a case report.<br />
Results: A 36-year old male came for consult due to conjunctival<br />
mass on the right eye. This was preceded 6 months ago with<br />
conjunctival hyperemia with no accompanying pain, itchiness<br />
or discharge. Two months after, with the persistence <strong>of</strong> the<br />
hyperemia, there was note <strong>of</strong> limbal mass. He was then assessed<br />
to have pterygium and was advised excision. Patient refused at<br />
the time and sought consult in our institution. On examination,<br />
visual acuity on the right is 20/25, on the left is 20/20. Anterior<br />
segment was unremarkable except for a raised, pinkish,<br />
conjunctival mass on the right eye with frond-like surface and<br />
dilated vessels measuring about 4x4 mm extending 1 mm into<br />
the temporal cornea. Patient underwent excision biopsy with<br />
cryotherapy. Histopathology <strong>of</strong> the mass revealed squamous<br />
cell carcinoma. A regimen <strong>of</strong> 4 times daily dosing <strong>of</strong> MMC 0.04%<br />
for 3 weeks, then discontinued for 3 weeks, then restarted for<br />
another 3 weeks, to complete 3 cycles was done postoperatively.<br />
Patient then followed up closely every 2 weeks. After completion<br />
<strong>of</strong> 3 cycles, there was no noted recurrence <strong>of</strong> the tumor and only<br />
conjunctival hyperemia was the adverse effect observed. This,<br />
however, disappeared upon discontinuation <strong>of</strong> the regimen.<br />
Conclusion: Squamous cell carcinoma <strong>of</strong> the conjunctiva is a<br />
slow growing tumor capable <strong>of</strong> extensive local tissue damage.<br />
Treatment would include complete surgical excision with<br />
cryotherapy. However, tumor recurrence is a concern. In this<br />
case, topical MMC proved to be an effective surgical adjunct in<br />
preventing its recurrence although longer period <strong>of</strong> follow up is<br />
recommended for further observation <strong>of</strong> recurrence.<br />
Key Words: Topical Mitomycin C, Conjunctival Mass, Excision<br />
Biopsy, Cryotherapy<br />
PP-26<br />
Wide Excision <strong>of</strong> a Large Upper Lid Sebaceous Gland<br />
Carcinoma with Reconstruction Using the Modified Cutler-<br />
Beard Technique<br />
Emerson Jay B. Molina, Alex U. Pisig,<br />
Margarita Justine O. Bondoc, Jo Anne P. Hernandez<br />
Cardinal Santos Medical Center, Philippines<br />
Objective: To report a case <strong>of</strong> a large upper eyelid sebaceous<br />
gland carcinoma, with subsequent reconstruction <strong>of</strong> the frozen<br />
section-guided excision defect using the modified Cutler-Beard<br />
procedure.<br />
Methods: This is a case report.<br />
Poster Presentations<br />
Results: An 81-year old Filipino female presented with an<br />
enlarging mass in the right upper eyelid. The lesion was noted<br />
8 months prior to consultation at our department. External exam<br />
on the left eye was unremarkable. Vision is 20/70 on the right<br />
and 20/100 on the left eye, with BCVA 20/50 for both. She is<br />
pseudophakic on both eyes, with the rest <strong>of</strong> the anterior segment<br />
36
Poster Presentations<br />
findings unremarkable. She had previously undergone incision<br />
and curettage <strong>of</strong> the same lesion at another institution, recurring<br />
rapidly after 4 weeks. She had a 1.5 x 1.5 cm multinodular, firm,<br />
non-tender, non-movable and well-circumscribed mass with some<br />
ulceration on her right upper eyelid and distortion <strong>of</strong> the lid margin.<br />
Subsequent referral and incision biopsy confirmed a sebaceous<br />
gland carcinoma. She underwent frozen-section guided wide<br />
excision <strong>of</strong> the tumor until resection margins were found to be<br />
clear. However, the conjunctiva was positive for pagetoid spread<br />
and focal subepithelial invasion. Orbital exenteration was not<br />
favored by the patient. Reconstruction was performed with the<br />
Modified Cutler-Beard technique followed by release <strong>of</strong> the bridge<br />
flap after 4 weeks as a second stage. Oncologic work-up was<br />
advised. Adjuvant treatment with Mitomycin C 0.04% eye drop<br />
solution was initiated at four times daily for a course <strong>of</strong> 2 weeks.<br />
The cosmetic result was satisfactory. The patient developed<br />
a corneal epithelial defect on the 2nd week after flap division.<br />
Mitomycin C was discontinued and the defect was treated<br />
successfully by bandage contact lens, topical antibiotics and<br />
lubrication. She remains stable at 3 months following excision<br />
with no recurrence observed.<br />
Conclusion: Sebaceous gland carcinoma is a relatively rare but<br />
potentially lethal malignancy <strong>of</strong> the eyelid. Wide excision <strong>of</strong> the<br />
tumor is mandatory and the resulting defect can be successfully<br />
repaired using the Cutler-Beard technique, producing a<br />
cosmetically favorable result.<br />
Key Words: Sebaceous gland carcinoma, Cutler-Beard<br />
procedure, Mitomycin C, Pagetoid spread<br />
PP-27<br />
Pfeiffer Syndrome-A Case Report<br />
Christine S. Siguan, Marissa N. Valbuena, Prospero Ma. C. Tuaño<br />
University <strong>of</strong> the Philippines-Philippine General Hospital,<br />
Philippines<br />
Objective: To report on a case <strong>of</strong> Pfeiffer Syndrome, discussing<br />
the diagnostic features <strong>of</strong> the disease and characteristics <strong>of</strong> each<br />
type.<br />
Methods: This is a descriptive, prospective report <strong>of</strong> one case<br />
seen at the UP-PGH, referred to the Department <strong>of</strong> Ophthalmology<br />
Orbit and Pediatric Ophthalmology Service.<br />
Results: The authors describe a newborn with cloverleaf skull,<br />
craniosynostosis, bilateral exorbitism, low-set ears, high arched<br />
palate, flat nasal bridge with fused elbows, long thin fingers on<br />
hands, broad thumbs, and medially deviated 2nd and 4th digit.<br />
The case reported was Pfeiffer syndrome type 2, which usually<br />
has poor prognosis.<br />
Conclusion: Pfeiffer syndrome is a clinically variable disorder.<br />
It has been divided into three types. Type 1 is associated with<br />
mild manifestations and normal intelligence and good prognosis.<br />
Types 2 and 3 have severe neurological compromise, poor<br />
prognosis and sporadic occurrence. Management for Pfeiffer<br />
syndrome is the primary treatment <strong>of</strong> crani<strong>of</strong>acial abnormalities<br />
associated with craniosynostosis.<br />
37<br />
Key Words: Pfeiffer syndrome, Cloverleaf skull, Craniosynostosis,<br />
Syndactyly<br />
PP-28<br />
Eyelid Neurilemmoma: A Vanishing Rarity<br />
Neal Vincent L. Torre, Fatima G. Regala<br />
DOH Eye Center East Avenue Medical Center, Philippines<br />
Objectives: To present a supposedly rare case <strong>of</strong> eyelid<br />
neurilemmoma and attempt to elucidate how this is possible.<br />
Methods: This is a case report <strong>of</strong> a 34-year old male who<br />
presented at Oculoplasty Clinic with an upper lid mass.<br />
Results: A 34-year old male was referred to the Oculoplasty<br />
Clinic with a slowly enlarging painless mass in his right upper<br />
eyelid for one and a half years. Eye examination revealed a<br />
round, well circumscribed, firm, slightly mobile, nontender mass,<br />
3.5 cm in diameter, the bulk <strong>of</strong> which was located in the medial<br />
third <strong>of</strong> the left upper eyelid. Orbital CT scan revealed a left<br />
medial orbital ovoid mass with well defined border measuring 3.3<br />
x 3.6 x 3.0 cm medial to and pressing the eyeball against the<br />
lateral orbital wall. Histopathologic evaluation revealed neoplastic<br />
Schwann cells whose nuclei tend to pallisade. They are arranged<br />
in interwoven ribbon bundles <strong>of</strong> pallisading cells alternating with<br />
acellular areas. The mass was removed en bloc with the aid <strong>of</strong><br />
cryoexcision. One year after surgery, no recurrence was noted, lid<br />
function was not diminished and it was aesthetically acceptable.<br />
In this case the lesion could come from any <strong>of</strong> the nerve branches<br />
supplying the upper eyelid, specifically its medial half, namely<br />
the superior orbital nerve, superior trochlear nerve, and inferior<br />
trochlear nerve, all <strong>of</strong> which contribute to the ophthalmic division<br />
<strong>of</strong> the trigeminal nerve, and the terminal twigs <strong>of</strong> the temporal<br />
branch <strong>of</strong> the facial nerve. Online review <strong>of</strong> literature revealed that<br />
there have been already 18 similar cases published.<br />
Conclusion: A slowly growing painless mass in the upper eyelid<br />
could be neurilemmoma. This report, as well as the growing<br />
number <strong>of</strong> case reports on this presentation, makes it a tenable<br />
differential diagnosis.<br />
Key Words: neurilemmoma, eyelid<br />
PP-29<br />
A Case <strong>of</strong> Basosquamous Carcinoma <strong>of</strong> the Central and<br />
Midface Area in a 62 year old Filipino Male<br />
Rhyan Francis T. Monsanto, Charmaine Y. Ang<br />
Fatima G. Regala<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
Objective: To describe the complications and surgical treatment<br />
<strong>of</strong> a case <strong>of</strong> neglected Basosquamous Carcinoma (10 years)<br />
involving the central and midface area in a 62 year old Filipino<br />
male.<br />
Method: Case Report
Results: The patient presented with a non-healing, spreading<br />
wound that involved the central forehead, medial right and<br />
left eyelids, nose and both mid-cheek areas. CT scan showed<br />
irregular shaped superficial s<strong>of</strong>t tissue mass involving the skin and<br />
subcutaneous fat <strong>of</strong> both naso-glabellar and pre-maxillary areas.<br />
Previous biopsy revealed Basosquamous carcinoma. Patient<br />
underwent wide excision with 5mm clearance and rush frozen<br />
section for control <strong>of</strong> margins <strong>of</strong> resection. Permanent medial<br />
tarsorrhapy done and the rest left to granulate. Reconstruction<br />
to be done later.<br />
Conclusion: Early treatment <strong>of</strong> Basosquamous Carcinoma will<br />
prevent its local destructive effect. Surgery with margin control<br />
can <strong>of</strong>fer cure for these patients.<br />
Key Words: wide excision, neglected Filipino, basosquamous<br />
carcinoma, basosquamous, carcinoma, midface<br />
PP-30<br />
A Case Report on an Unusual Intraorbital Foreign Body<br />
Jessica Guzman, Fatima G. Regala, Charmaine Y. Ang<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
Objective: To present a case <strong>of</strong> an orbital trauma, producing an<br />
unusual intraorbital foreign body with no globe involvement.<br />
Methods: This is a case report on an 18 year-old male with an<br />
intraorbital toothbrush extending to the nasal cavity. He presented<br />
with an embedded handle in the right orbit associated with<br />
periorbital swelling. Initial visual acuity was OD 20/80 improved to<br />
20/32-2 by pinhole, with commotio retinae and limited extraocular<br />
muscle movement in all gazes. He underwent removal <strong>of</strong> the<br />
toothbrush head, repair <strong>of</strong> inferior oblique and upper tarsus.<br />
Reinsertion <strong>of</strong> levator aponeurosis into the tarsal plate and repair<br />
<strong>of</strong> lid margin were also done. Intraoperative findings revealed that<br />
the toothbrush went through the medial wall into the nasal cavity<br />
with transection <strong>of</strong> the inferior oblique, levator aponeurosis and<br />
upper lid margin.<br />
Results: A 6cm by 1cm toothbrush with intact bristles was<br />
removed from the wound. The swab specimen revealed moderate<br />
growth <strong>of</strong> Enterobacter species. The patient was maintained on<br />
topical antibiotics, intravenous antibiotics for 3 days then oral<br />
antibiotics for 7 days. Visual acuity improved with resolution<br />
<strong>of</strong> commotio retinae. Improvements in extraocular muscle<br />
movements were observed, however there was residual ptosis.<br />
Conclusion: Intraorbital foreign bodies are quite uncommon,<br />
especially those with no globe involvement. Imaging is needed<br />
prior to planning the removal <strong>of</strong> intraorbital foreign body to assess<br />
the exact location. Indications for removing an intraorbital foreign<br />
body include the nature <strong>of</strong> the foreign body and wound exposure.<br />
Antibiotic coverage is important to prevent secondary infections.<br />
Key Words: intraorbital foreign body<br />
PP-31<br />
Bilateral Proptosis with Visual Loss: A Case Report<br />
J. Rotsen Evaristo, Fatima G. Regala<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
Objective: To report a case <strong>of</strong> chronic bilateral proptosis with<br />
visual loss.<br />
Methods: This is a descriptive case report <strong>of</strong> an 18-year-old<br />
male presenting with bilateral proptosis and visual loss caused by<br />
a tumor originating from the nasal cavity.<br />
Results: Biopsy <strong>of</strong> the nasal mass revealed histopathologic<br />
findings consistent with a nasal polyp.<br />
Conclusion: This is a case presentation <strong>of</strong> a nasal mass which<br />
extended intracranially, causing bilateral proptosis and visual<br />
loss. A tissue biopsy <strong>of</strong> the mass revealed it was a nasal polyp,<br />
however, the progression <strong>of</strong> signs and symptoms raises the<br />
suspicion that a malignant process is involved.<br />
Key Words: Bilateral, Visual loss<br />
PP-32<br />
Carcinosarcoma in a Newborn<br />
Aimee C. Ng Tsai<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
Objective: To describe a rare case <strong>of</strong> carcinosarcoma, probably<br />
from a metastatic Wilm’s tumor.<br />
Method: This is a case report.<br />
Poster Presentations<br />
Result: A newborn was noted to have a mass on the left eye<br />
upon delivery and was subsequently referred to our institution<br />
for evaluation. On initial consult at 4 days <strong>of</strong> age, a 3.5 x 3cm<br />
bleeding, fungating mass with areas <strong>of</strong> hematoma was noted<br />
arising from the conjunctiva. Initial impression was embryonal<br />
conjunctival mass, to consider malignancy. Other physical<br />
examination findings were normal except for the conjunctival<br />
mass. There was rapidly progressive enlargement <strong>of</strong> the mass<br />
accompanied by pr<strong>of</strong>use bleeding. She subsequently underwent<br />
examination under anesthesia, cryoexcision <strong>of</strong> conjunctival<br />
mass, and lid repair. Intraoperatively, the mass was found to<br />
be originating from the preseptal orbicularis muscle and was<br />
therefore thought to be a rhabdomyosarcoma. A 70 x 50 x 40<br />
mm3 tan-brown, encapsulated, lobulated, and smooth mass was<br />
obtained. Histopathologic findings turned out to be consistent<br />
with carcinosarcoma, rule out metastatic Wilm’s tumor. Contrastenhanced<br />
cranial CT scan done post-operatively only showed s<strong>of</strong>t<br />
tissue thickening in the left eyelid. Patient is still for Nephrologic<br />
work up and immunostaining.<br />
Conclusion: Metastatic process can present with a conjunctival<br />
mass and should be included in the differential diagnosis <strong>of</strong> such<br />
masses.<br />
Key Words: carcinosarcoma, embryonal tumor,<br />
rhabdomyosarcoma, wilm’s tumor<br />
38
PP-33<br />
Comparative Study <strong>of</strong> Using Dermal Fat Graft Alone and<br />
Dermal Fat Graft with an Orbital Implant in Children<br />
Majourette Dy Varela, Fatima G. Regala, Charmaine Y. Ang<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
Objective: To compare the outcome <strong>of</strong> using Dermal Fat<br />
Transplant alone and Dermal Fat Grafting with a small orbital<br />
implant in the pediatric age group.<br />
Methods: Autologous DFG was use in 3 children with pthisis<br />
bulbi and one who had an enucleation without any orbital implant.<br />
A 1 x 1.5 x 1 cm dermal fat graft harvested from the buttock<br />
was used in all patients. Two patients with pthisis bulbi had a<br />
10mm sphere implanted in the posterior Tenon’s followed by<br />
dermal fat grafting. Both horizontal recti muscles were sutured<br />
to the inferior edge <strong>of</strong> the dermis. The two other patients had<br />
immediate dermal fat grafting. No intra-operative complications<br />
were noted. Follow-up range from16 to 78 weeks. No signs <strong>of</strong><br />
graft rejection were observed. This was also seen in the patient<br />
who had chemotherapy for retinoblastoma. There was also no<br />
clinical difference in both groups.<br />
Results: The surface area problem in the patients were corrected<br />
at the same time having successfully fitted with a prosthesis<br />
Conclusion: In the pediatric age group, the use <strong>of</strong> dermal fat<br />
graft as the sole source or together with an orbital implant can<br />
correct volume loss. At the same time, correction <strong>of</strong> the surface<br />
area deficiency was observed.<br />
Key Words: Children, Contracted socket, Dermal Fat Graft,<br />
Contracted socket, Dermal Fat Graft<br />
PP-34<br />
Use <strong>of</strong> a Modified Metal Guide <strong>of</strong> a Bicanalicular Intubation<br />
Stent in Transected Canalicular Repair<br />
Marco A. Tumalad, Charmaine Y. Ang, Fatima G. Regala<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
Objectives: To describe the use <strong>of</strong> a modified metal guide <strong>of</strong><br />
a Bicanalicular Intubation Stent in the repair <strong>of</strong> a traumatically<br />
transected canaliculus. To outline modification <strong>of</strong> the metal guide<br />
<strong>of</strong> a bicanalicular stent into a pigtail probe. To report outcome in<br />
terms <strong>of</strong> surgical facilitation and patency restoration.<br />
Methods: All patients with traumatically transected canaliculi less<br />
than 24-hours from incident were recruited from the East Avenue<br />
Medical Center, Emergency Room Department. All transected<br />
canaliculi were repaired using our modified bicanalicular stents under<br />
general anesthesia within 48 hours. We modified a bicanalicular stent,<br />
by fashioning its malleable metal guide into a pigtail probe creating a<br />
one-piece instrument consisting <strong>of</strong> a pigtail probe, complete with the<br />
silicon tube trailing behind. This allowed us to stent the canaliculus up<br />
through the transection by passing the probe through the unaffected<br />
upper punctum and out the transection with the silicon stent threaded<br />
into place. After successful repair, silicon stents were kept in-place for<br />
three months. After removal, dye disappearance testing was done.<br />
39<br />
Poster Presentations<br />
Results: There were 10 patients included in this study. All<br />
underwent repair using a bicanalicular stent whose metal guide<br />
was fashioned into a pigtail probe. This eliminated the need to<br />
thread the stent and facilitated reattachment <strong>of</strong> the transected<br />
canaliculus. The silicone stent was removed after 3 months.<br />
Surgeries were successful in stenting the transected canaliculi,<br />
with anatomical restoration <strong>of</strong> the lid. All had normal DDT.<br />
Conclusion: Modifying the metal guide <strong>of</strong> a bicanalicular stent<br />
into a pigtail probe facilitated canalicular repair and is associated<br />
with a high degree <strong>of</strong> success.<br />
Key Words: Bicanalicular Silicon Stent, Prolene, Transected<br />
Canaliculus, Pigtail Probe Dye, Disappearance Test<br />
PP-35<br />
Cavernous Hemangioma <strong>of</strong> the Orbit: An Unusual Presentation<br />
Clarissa H. Tuliao, Anthony Christopher G. Ortiz, Evelyn S.<br />
Morabe, Ma. Lourdes R. Nañagas<br />
Jose R. Reyes Memorial Medical Center, Philippines<br />
Objective: To present a case <strong>of</strong> cavernous hemangioma <strong>of</strong> the<br />
orbit presenting as multiple lobulated lesions.<br />
Method: Case presentation<br />
Discussion: A 59 year old female with a two year history <strong>of</strong><br />
gradual progressive proptosis <strong>of</strong> the right eye with associated<br />
blurring <strong>of</strong> vision <strong>of</strong> the same eye. Ophthalmologic examination<br />
showed a VA <strong>of</strong> hand movement with good light projection, OD<br />
and a BCVA <strong>of</strong> 20/20, OS. The right eye was displaced forward,<br />
downward and medially. Hertel’s exophthalmometry showed 5<br />
mm proptosis. Mature cataract was noted on the right eye, which<br />
could explain the concomitant blurring <strong>of</strong> vision. Ophthalmologic<br />
findings for the left eye were normal. CT Scan with contrast<br />
showed lobulated hyperdense strongly enhancing mass in the<br />
right orbit involving the conal/intraconal region closely abutting<br />
the optic nerve sheath and lacrimal gland. The ocular wall was<br />
smooth, sharply defined and <strong>of</strong> normal thickness. Operative<br />
findings showed 3 discrete sausage-shaped masses connected<br />
by a fibrous band which were excised completely and submitted<br />
for histologic examination. Histopathology showed large<br />
cavernous spaces containing red blood cells, consistent with<br />
cavernous hemangioma. Cavernous hemangioma is the most<br />
common neoplasm <strong>of</strong> the orbit in adults. Growth <strong>of</strong> this mass<br />
usually causes axial proptosis but our patient presented with<br />
forward, downward, and inward deviation, likely due to extension<br />
<strong>of</strong> the mass to the area <strong>of</strong> the lacrimal gland as seen on CT scan.<br />
Thus, pleomorphic adenoma <strong>of</strong> the lacrimal gland was included<br />
in our differential diagnosis. The multiple nodular presentation <strong>of</strong><br />
the tumor also led to a consideration <strong>of</strong> lymphangioma. Inspite<br />
<strong>of</strong> the atypical lobulation and seeming extension into the area<br />
<strong>of</strong> the lacrimal gland, cavernous hemangioma was still mainly<br />
considered because <strong>of</strong> its frequency <strong>of</strong> occurrence, the slowly<br />
progressive course <strong>of</strong> the patient’s condition, and the CT scan<br />
findings <strong>of</strong> a homogenous, hyperdense, strongly enhancing<br />
mass with no sign <strong>of</strong> bone invasion. Timothy et. al. reviewed<br />
the presentation <strong>of</strong> cavernous hemangioma and found 4 reports
that described multiple lesions in the one orbit in none <strong>of</strong> six, one<br />
<strong>of</strong> 13, two <strong>of</strong> 66, and five <strong>of</strong> 85 patients. Mirjana Nagulic, et. al.<br />
reported a case <strong>of</strong> multiple recurrences after complete excision<br />
in a case <strong>of</strong> multi-lobulated tumor. Hence, long term followup<br />
is recommended especially in multi-lobulated cavernous<br />
hemangioma.<br />
Conclusion: Cavernous hemangioma may present as a multilobulated<br />
strongly enhancing mass and must be included in<br />
the differential diagnosis <strong>of</strong> such orbital lesions in adults. Long<br />
term follow-up is recommended because <strong>of</strong> reports <strong>of</strong> multiple<br />
recurrences after excision, especially <strong>of</strong> multi-lobulated tumors.<br />
Key Words: Multi-lobulated, Hemangioma, Intraconal, Orbit,<br />
Tumor, Proptosis<br />
PP-36<br />
Sebaceous Gland Carcinoma <strong>of</strong> the Eyelid Presenting as a<br />
Chalazion: A Case Report<br />
Pearl Trisha M. Padilla, Leonardo R. Mangubat<br />
Makati Medical Center, Philippines<br />
Objective: To discuss a case <strong>of</strong> a 38-year old female<br />
presenting with a slowly enlarging, painless, irregular nodular<br />
lesion resembling a chalazion on the left upper lid, diagnosed<br />
histopathologically with sebaceous gland carcinoma.<br />
Methods: Complete eye exam and baseline measurements were<br />
acquired. A prompt excision <strong>of</strong> the nodule with tissue biopsy was<br />
done under local anesthesia.<br />
Results: Tissue biopsy results confirmed the diagnosis<br />
<strong>of</strong> Sebaceous Gland Carcinoma <strong>of</strong> the eyelid. The goal <strong>of</strong><br />
management is to perform wide excision and to determine the<br />
extent <strong>of</strong> malignant spread, if any. Management included a<br />
referral to orbit and oculoplastic service. The proposed surgical<br />
plan six weeks post-operatively is to perform wide excision with<br />
frozen section <strong>of</strong> the lines <strong>of</strong> excision and reconstruction under<br />
local anesthesia.<br />
Conclusion: Current recommended treatment for Sebaceous<br />
Gland Carcinoma <strong>of</strong> the lid is wide excision <strong>of</strong> the involved tissue<br />
with histological monitoring <strong>of</strong> surgical margins. For extensive<br />
involvement, however, total exenteration may be necessary. This<br />
report emphasizes the importance <strong>of</strong> maintaining a high index <strong>of</strong><br />
suspicion on the ophthalmologists part when presented with such<br />
a history and a progressing nodular lesion. An early biopsy may<br />
likewise prove useful and lifesaving in potentially lethal tumors.<br />
Key Words: Wide excision<br />
PP-37<br />
Orbital Metastasis Arising From Adenocarcinoma <strong>of</strong> the Lung<br />
Bernardo Joaquin Tuaño, Yvette Marie Santiago<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
Objective: To present a case report <strong>of</strong> a 57 year old female with<br />
a one year history <strong>of</strong> ptosis <strong>of</strong> the left eye.<br />
Methods: On physical examination, there was a 2mm left<br />
hypoglobus with fullness over the left eyebrow. There was no<br />
resistance to retropulsion. Exophthalmometry revealed a 5mm<br />
proptosis on the left eye (15mm) when compared to the right<br />
(10mm). The initial approach to orbital disease <strong>of</strong> this patient<br />
was to determine if the proptosis was due to a vascular lesion,<br />
endocrine problem, inflammatory condition or a neoplastic<br />
disease.<br />
Results: After narrowing the differentials, a computed<br />
tomography (CT) scan <strong>of</strong> the orbits was requested to help<br />
determine the type <strong>of</strong> orbital disease. The CT scan showed lytic<br />
calvarial lesions involving the left frontal and sphenoid bones,<br />
including the left lateral orbital wall, with associated intraorbital<br />
and intracranial s<strong>of</strong>t tissue densities. A metastatic process (from<br />
a yet unspecified primary focus) is primarily considered. Further<br />
work up was done and it revealed a right retrobronchial mass<br />
abutting the major fissure and slightly indenting on the posterior<br />
wall <strong>of</strong> the right mainstem bronchus. A CT guided biopsy <strong>of</strong> the<br />
right retrobronchial lung mass showed findings consistent with<br />
adenocarcinoma.<br />
Conclusion: Although rare, orbital metastasis from a primary<br />
cancer should always be a consideration and should be<br />
investigated, because patients can initially present with proptosis.<br />
Key Words: Adenocarcinoma <strong>of</strong> the lung, Orbital Metastasis,<br />
Proptosis<br />
PP-38<br />
Poster Presentations<br />
Spontaneous Resolution <strong>of</strong> Dilated Superior Ophthalmic Vein<br />
in a Patient with Indirect Carotid-cavernous Sinus Fistula<br />
Karen Joyce G. Castro, Prospero Ma. C. Tuaño<br />
St Luke’s Medical Center, Philippines<br />
Objective: To describe a case <strong>of</strong> spontaneous resolution <strong>of</strong><br />
dilated superior ophthalmic vein in a patient with indirect carotidcavernous<br />
sinus fistula presenting with proptosis and marked<br />
congestive ophthalmopathy.<br />
Method: A 58 y/o male, Filipino, diabetic, presented with sudden<br />
pain, blurring <strong>of</strong> vision, diplopia, and proptosis <strong>of</strong> the right eye.<br />
There was no history <strong>of</strong> trauma. Examination revealed vision<br />
<strong>of</strong> 20/400 on the right eye, with ptosis, marked congestion,<br />
chemosis, limitation <strong>of</strong> ocular motility, and (+) RAPD. There was<br />
no bruit. The intraocular pressure (IOP) was 17mmHg.<br />
Results: CT scan and MRI/MRA <strong>of</strong> brain and orbits revealed<br />
dilated superior ophthalmic vein on the right with undue<br />
enhancement <strong>of</strong> walls. The extraocular muscles <strong>of</strong> the right eye<br />
showed diffused thickening and enhancement. Cavernous sinus<br />
also showed haziness and enhancement. No distinct mass lesion<br />
was noted. An initial diagnosis <strong>of</strong> orbital inflammatory disease<br />
versus an infectious etiology was considered. Patient was started<br />
on antibiotics and steroid. There was marked improvement<br />
after 3 weeks with vision <strong>of</strong> 20/40 on the right and improved<br />
ocular motility. However, chemosis and dilated conjunctival<br />
vessels persisted. Steroid was slowly tapered. Review <strong>of</strong> orbital<br />
40
Poster Presentations<br />
imaging was done and indirect carotid-cavernous sinus fistula<br />
was considered. CT angiography was planned to confirm the<br />
diagnosis. While waiting for funds for the procedure, chemosis<br />
and dilated conjunctival vessels resolved. Repeat orbital CT scan<br />
with contrast after 4 months revealed spontaneous resolution <strong>of</strong><br />
dilated superior ophthalmic vein.<br />
Conclusion: A high index <strong>of</strong> suspicion is necessary in diagnosing<br />
a case <strong>of</strong> indirect carotid-cavernous sinus fistula in a patient<br />
without any history <strong>of</strong> trauma presenting with proptosis, marked<br />
congestive ophthalmopathy, and orbital imaging showing dilated<br />
superior ophthalmic vein. Spontaneous resolution <strong>of</strong> dilated<br />
superior ophthalmic vein occurs in an indirect type <strong>of</strong> carotidcavernous<br />
sinus fistula. Orbital imaging such as CT scan and<br />
MRI/MRA are important in the diagnosis.<br />
Key Words: dilated superior ophthalmic vein, proptosis, carotid<br />
cavernous-sinus fistula<br />
PP-39<br />
Two-Stage Reconstruction <strong>of</strong> Upper and Lower Anterior<br />
Lamellar Eyelid Defect after Excision <strong>of</strong> Intradermal Nevus<br />
Pius Jonas F. Ocampo, Mary Rose Pe-Yan<br />
St. Luke’s Medical Center, Philippines<br />
Objective: The purpose <strong>of</strong> this study is to report a two-stage<br />
surgical procedure to reconstruct a large upper and lower anterior<br />
lamellar eyelid defect.<br />
Methods: The study design is a case report. The patient has<br />
an upper and lower eyelid (anterior lamellae) defect (horizontal<br />
extent: >90%, both upper and lower, vertical extent: > 15mm)<br />
after tumor excision (Intradermal Nevus). A two-stage eyelid<br />
reconstruction using a full thickness skin graft with apposition <strong>of</strong><br />
upper and lower eyelid skin and a secondary release and repair<br />
<strong>of</strong> blepharoptosis were done. The outcomes were an upper and<br />
lower eyelid anatomic cosmetic appearance and lid closure<br />
function.<br />
Results: Good anatomic cosmetic appearance and lid closure<br />
function were achieved after the second surgery. No remarkable<br />
ocular and extra-ocular side effects or complications were noted.<br />
Conclusions: In a two-stage procedure, assuring the integrity<br />
and viability <strong>of</strong> the graft prior to repair <strong>of</strong> blepharoptosis was done<br />
to repair large upper and lower eyelid (anterior lamellae) defect.<br />
Key Words: Eyelid, anterior, Reconstruction, lamellae<br />
PP-40<br />
Painful Ophthalmoplegia<br />
Honeylen Maryl Tiu Teo, Prospero Ma. C. Tuaño,<br />
Buenjim Mariano<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
Objective: To present a case report on painful ophthalmoplegia<br />
diagnosed as Tolosa Hunt Syndrome (THS)<br />
41<br />
Methods: We reported a case <strong>of</strong> a 49 year-old male who<br />
presented with periorbital pain, eye redness, blurred vision, lid<br />
drooping, and limited movement <strong>of</strong> the right eye. Physical exam<br />
revealed no light perception, proptosis; and involvement <strong>of</strong> all<br />
extraocular muscles, optic nerve, and conjunctival vessels on the<br />
right eye. History and ophthalmologic exam gave clues on the<br />
possible location <strong>of</strong> the lesion, and was confirmed through MRI.<br />
Trial <strong>of</strong> steroids using intravenous dexamethasone 5mg every<br />
6 hours for 3 days was done, and the patient was observed for<br />
improvement <strong>of</strong> the ophthalmologic signs and symptoms.<br />
Results: Orbital MRI with contrast revealed a homogeneously<br />
enhancing right intraconal s<strong>of</strong>t tissue mass extending into<br />
the posterior right eyeball, with radiologic considerations <strong>of</strong><br />
inflammatory, infectious, and neoplastic lesion. The patient<br />
was diagnosed with THS based on the International Headache<br />
Society 2004 Criteria for THS. There is currently no protocol or<br />
standardized dose <strong>of</strong> steroids for the treatment <strong>of</strong> THS. With<br />
the trial <strong>of</strong> steroids, the signs and symptoms <strong>of</strong> periorbital pain,<br />
conjunctival congestion, ptosis, ophthalmoplegia, and proptosis<br />
improved during the three-day admission. However, the visual<br />
acuity showed no improvement.<br />
Conclusion: Painful ophthalmoplegia has various etiologies.<br />
A thorough history, ophthalmologic exam, imaging, and trial <strong>of</strong><br />
steroids are necessary to confirm the diagnosis <strong>of</strong> Tolosa Hunt<br />
Syndrome.<br />
Key Words: Hunt, Syndrome, ophthalmoplegia, Tolosa, Hunt,<br />
Syndrome, ophthalmoplegia<br />
PP-41<br />
Canalicular Reconstruction in Long Standing Healed<br />
Canalicular Laceration<br />
Simeon Arni A. Pagdanganan, Reynaldo M. Javate<br />
University <strong>of</strong> Santo Tomas Hospital, Philippines<br />
Objective: Canalicular reconstruction in long standing healed<br />
canalicular laceration can be managed by dacryocystotomy<br />
followed by retrograde canalicular intubation. The surgical<br />
technique and significance <strong>of</strong> this procedure are discussed.<br />
Methods: A retrospective case study <strong>of</strong> a 26 year old male who had<br />
a history <strong>of</strong> long standing healed canalicular laceration following<br />
trauma to his right lower lid. He underwent dacryocystotomy with<br />
retrograde canalicular intubation under general anesthesia at<br />
University <strong>of</strong> Santo Tomas Hospital Eye Center on year <strong>2012</strong>.<br />
Results: Epiphora improved.<br />
Conclusion: Dacryocystotomy followed by retrograde canalicular<br />
intubation is a technique that can be used for canalicular<br />
reconstruction in patients with long standing healed canalicular<br />
laceration.<br />
Key Words: Dacryocystotomy followed by retrograde canalicular<br />
intubation, long standing healed canalicular laceration
PP-42<br />
Microendoscopic Recanalization with Silicone Intubation<br />
for the Treatment <strong>of</strong> Canalicular and Primary Acquired<br />
Nasolacrimal Duct Obstruction<br />
Armida L. Suller, Reynaldo M. Javate, Raul T. Cruz, Jr.<br />
University <strong>of</strong> Santo Tomas Hospital, Philippines<br />
Objective: To determine the surgical outcome <strong>of</strong> microendoscopic<br />
canalicular trephination (MCT) and endoscopic lacrimal duct<br />
recanalization (ELDR) with silicone intubation in restoring the<br />
passage <strong>of</strong> tears in patients with canalicular and primary acquired<br />
nasolacrimal duct obstruction (PANDO).<br />
Methods: This is a prospective, noncomparative, interventional<br />
case series <strong>of</strong> patients presenting with epiphora secondary to<br />
canalicular and/or nasolacrimal duct obstruction (NLDO) who<br />
underwent MCT and ELDR with silicone intubation from June<br />
2009 to March <strong>2012</strong>. A mean follow-up period <strong>of</strong> 10.2 months (3.0<br />
to 28.6 months) was conducted after stent removal and evaluation<br />
for anatomical and functional patency was done.<br />
Results: Twenty-five patients with a mean age <strong>of</strong> 64.6 years<br />
(36 to 86 years) were included in the study. Nineteen cases had<br />
canalicular obstruction while 26 cases had complete NLDO.<br />
Silicone stents were removed at a mean <strong>of</strong> 8.1 months (3.1 to<br />
12.0 months) after the surgery. The anatomic and functional<br />
success rate for patients with canalicular obstruction was 94.7%<br />
(95% CI, 74 to 99.9%). Patients with complete NLDO achieved<br />
an anatomic success rate <strong>of</strong> 96.2% (95% CI, 80.4 to 99.9%)<br />
and a functional success rate <strong>of</strong> 84.6% (95% CI, 65.1 to 95.6%).<br />
Two cases, 4.44% (95% Cl, 0.5 to 15.1%) had punctal slitting<br />
associated with silicone intubation. No other minor or major<br />
complication was observed.<br />
Conclusion: MCT and ELDR with silicone intubation allow<br />
precise localization, removal <strong>of</strong> obstruction, avoiding creation <strong>of</strong><br />
a false passage, preventing adhesion <strong>of</strong> the mucosal lining <strong>of</strong> the<br />
lacrimal excretory system; thus, increasing the success rates <strong>of</strong><br />
the procedures.<br />
Key Words: endoscopic lacrimal duct recanalization, silicone<br />
intubation, microendoscopic canalicular, trephination, canalicular<br />
obstruction, nasolacrimal duct obstruction<br />
Pathology and Intraocular Tumors<br />
PP-43<br />
Adenoid Cystic Carcinoma <strong>of</strong> the Lacrimal Gland: A Case Report<br />
Mamerto G. Capero, Jr., Anthony Christopher G. Ortiz,<br />
Evelyn S. Morabe, Ma. Lourdes M. Nañagas<br />
Jose R. Reyes Memorial Medical Center, Philippines<br />
Case Summary: Adenoid cystic carcinoma <strong>of</strong> the lacrimal gland<br />
is a very rare condition, accounting for only 1.6% <strong>of</strong> all orbital<br />
tumors. This is a case <strong>of</strong> a 31yo male seen at our clinic due to<br />
a 3 month history <strong>of</strong> protrusion <strong>of</strong> the left eye with pain scale <strong>of</strong><br />
3/10, associated with progressive blurring <strong>of</strong> vision and redness.<br />
Patient had a visual acuity <strong>of</strong> Counting fingers at 3ft, Proptosis<br />
<strong>of</strong> 9mm with Hertel?s Exophthalmometry, and EOM <strong>of</strong> -3 on all<br />
fields <strong>of</strong> gaze OS. A palpable, firm, tender, non-movable mass on<br />
the superolateral aspect <strong>of</strong> the left orbit was noted. CT scan with<br />
Orbital cuts revealed lacrimal Gland Mass probably malignant with<br />
metastasis to the left part <strong>of</strong> the frontal lobe <strong>of</strong> the brain and bone<br />
invasion. Exenteration <strong>of</strong> the left eye with Craniotomy excision<br />
<strong>of</strong> the tumor at the left frontal lobe was done together with the<br />
neurosurgery team. TNM staging was noted at T2NoM1 with a<br />
Histologic Grade <strong>of</strong> G3 due to malignant cells mainly basaloid<br />
(solid) pattern. Perineural invasion was also noted. Adenoid<br />
cystic Carcinoma is a very aggressive tumor in which there is no<br />
established treatment protocol yet. However, early detection and<br />
prompt intervention may improve treatment outcome and survival<br />
rate. On the basis <strong>of</strong> cases previously studied, exenteration plus<br />
radiation was the most efficacious treatment.<br />
Key Words: Adenoid Cystic Carcinoma <strong>of</strong> the Lacrimal Gland<br />
PP-44<br />
Poster Presentations<br />
Primitive Neuroectodermal Tumour <strong>of</strong> the Orbit in a 14 Year<br />
Old Male with Absolute Glaucoma Post Evisceration:<br />
A Case Report<br />
Manuel Benjamin B. Ibañez, IV, Leonardo R. Mangubat,<br />
Ramon Mario Ongsiako<br />
Makati Medical Center, Philippines<br />
Objective: To describe a rare case <strong>of</strong> a peripheral primitive<br />
neuroectodermal tumour <strong>of</strong> the orbit in a 14 year old boy.<br />
Methods: A 14 year old male presented with a 2 month history<br />
<strong>of</strong> an enlarging, mass on an anophthalmic socket. Complete<br />
eye exam was done and baseline characteristics were taken on<br />
presentation. A wedge biopsy <strong>of</strong> the orbital mass was done and<br />
specimens were sent for histopathology and immunostaining.<br />
Results: Wedge biopsy results showed round cell tumour, to<br />
consider high grade lymphoma. Further immunostaining revealed<br />
primitive neuroectodermal tumour.<br />
Conclusion: Primitive neuroectodermal tumour occurring<br />
peripherally is rare with only 9 reported cases. It is diagnosed<br />
through immunohistochemistry. There is no standardized<br />
treatment but goal <strong>of</strong> therapy is to remove as much tumour tissue<br />
as possible followed by chemotherapy and possible irradiation.<br />
Key Words: Primitive Neuroectodermal Tumour, Orbital Mass<br />
42
Poster Presentations<br />
Pediatric Ophthalmology and Strabismus<br />
PP-45<br />
A Case <strong>of</strong> Bilateral Persistent Fetal Vasculature in a<br />
Premature Infant<br />
Arturo B. Capulong, Emilio Macias, III, Evelyn Morabe<br />
Jose R. Reyes Memorial Medical Center, Philippines<br />
Case Summary: While frequently unilateral, persistent fetal<br />
vasculature (PFV) has been reported to be bilateral in 2.4-14%<br />
<strong>of</strong> cases. We report an interesting case <strong>of</strong> a 5month old baby<br />
born premature, 1st <strong>of</strong> twins, with bilateral leukocoria. ROP was<br />
considered in the differential diagnosis <strong>of</strong> this case because <strong>of</strong><br />
the bilaterality, the history <strong>of</strong> prematurity and the LBW <strong>of</strong> 1500<br />
gms. However, because <strong>of</strong> the findings <strong>of</strong> microphthalmia, the<br />
presence <strong>of</strong> retrolental membrane and optic stalk without the<br />
peripheral retinal cicatricial findings <strong>of</strong> ROP, PFV was considered<br />
the more likely diagnosis.<br />
Key Words: optic stalk, persistent primary vitreous<br />
PP-46<br />
Moebius Syndrome Associated with Exposure to Misoprostol<br />
JC Martin S. Cabrera, Bibhuti R. Thapa, Emilio L. Macias, III,<br />
Evelyn S. Morabe, Ma. Lourdes Nañagas<br />
Jose R. Reyes Memorial Medical Center, Philippines<br />
Objective: To discuss and help in recognition <strong>of</strong> a rare<br />
developmental anomaly. To report a case <strong>of</strong> child, born with<br />
Moebius Syndrome following exposure in utero to misoprostol for<br />
elective abortion.<br />
Method: A case report<br />
Case: An 8 years old boy, born full term by NSD to 21 years<br />
old primigravid at health center delivered by midwife with-out<br />
any fetomaternal complications. At 3 months age <strong>of</strong> gestation,<br />
the mother attempted abortion with misopro-stol taking 1 tablet<br />
orally. At birth, deviation <strong>of</strong> the eyes was noted. At 1 year <strong>of</strong><br />
age, deviation <strong>of</strong> mouth with incomplete closure <strong>of</strong> left eye was<br />
noted. Patient had normal growth but delay in development <strong>of</strong><br />
speech. On ophthalmologic examination, VA was 20/50 -> 20/25<br />
on right, 20/160 -> 20/63 on left eye. Restriction <strong>of</strong> movement <strong>of</strong><br />
eye laterally on both eyes was noted. Lagophthalmos, bilateral<br />
epicanthal folds with microcornea <strong>of</strong> left eye was observed. On<br />
slit lamp examination, positive punctuate epithelial dye uptake<br />
was present. Fundus examination was normal. Krimsky test on<br />
Right eye fixating was 35 prism diopter LHT and on cover uncover<br />
test, 35LHT on primary gaze, 20RET on right gaze and 45LHT<br />
with 50LET on left gaze was found. Atropine refraction was+ 2.50<br />
diopter sph -1.50 diopter cyl X180 on right eye and +4.50 diopter<br />
sph - 1.00 diopter cyl X180 on left eye. Amblyopia in this patient<br />
was most probably due to strabismus and anisometropia. Other<br />
non ophthalmologic findings were deviation mouth with deviation<br />
<strong>of</strong> tongue on protusion, and could not properly smile causing<br />
mask like face and club foot. Eye glasses was provided which<br />
improved the visual acuity to 20/32 on right eye and 20/100 on left<br />
43<br />
eye. Symptomatic treatment was done with ointments and eye<br />
patching started. Patient was suggested for regular followup and<br />
muscle surgery was planned.<br />
Case Discussion: In the clinical setting, the findings like various<br />
gaze palsies, associated with mask-like facies, incomplete eyelid<br />
closure, deviation <strong>of</strong> mouth and tongue, and speech impairment<br />
raises a high index <strong>of</strong> suspicion for Möbius syndrome, a disorder<br />
primarily involving the facial and abducens motor nerves. Ocular<br />
conditions that may present with with limited lateral rectus<br />
function include congenital sixth-cranial-nerve palsy, and Duane<br />
syndrome. These conditions, however, do not have signs and<br />
symptoms characteristic <strong>of</strong> facial nerve involvement. Facial nerve<br />
involvement with deviation <strong>of</strong> mouth can be seen in Assemetric<br />
crying facies but doesn’t have any ocular involvement. All these<br />
ocular and non-ocular findings can be seen in Möbius syndrome.<br />
Von Graefe initially described a patient with congenital facial<br />
diplegia in 1880 but Paul Julius Möbius, a German neurologist,<br />
reviewed more cases and reported an association with congenital,<br />
nonprogressive bilateral facial and abducens nerve palsy along<br />
with other systemic abnormalities.Later, Verzijl suggested<br />
facial palsy with impairment <strong>of</strong> ocular abduction as the primary<br />
criterion for Möbius syndrome. The etiology <strong>of</strong> Möbius syndrome<br />
is multifactorial, and several theories have been proposed, with<br />
the most supported theory being that <strong>of</strong> transient ischemic or<br />
hypoxic insult to the fetus. Other infectious and genetic etiologies<br />
have also been proposed. In addition, the use <strong>of</strong> misoprostol, a<br />
prostaglandin-E1 analog and abortifacient during pregnancy, has<br />
also been implicated. Misoprostol is a synthetic prostaglandin<br />
E analogue with greater antisecretory and mucosal-protective<br />
activity than natural prostaglandins. It is used to prevent and treat<br />
gastrointestinal lesions induced by nonsteroidal anti-inflammatory<br />
drugs and upper gastrointestinal ulceration. It is not<br />
recomended during early pregnancy, because it may mended<br />
stimulate uterine contractions and cause vaginal bleeding,<br />
which may endanger fetal survival. Misoprostol has been<br />
used for the elective induction <strong>of</strong> abortion. Congenital defects<br />
following prenatal exposure in early pregnancy to misoprostol<br />
include skull defects, bladder exstrophy, arthrogryposis, cranial<br />
nerve palsies, facial malformations, terminal transverse limb<br />
defects, and Moebius sequence. Möbius syndrome is congenital,<br />
non progressive. No definitive treatment available. Nonsurgical<br />
ophthalmologic management include early detection and<br />
treatment <strong>of</strong> amblyopia giving best correction and symptomatic<br />
treatment. Amblyopia in these patient might be due to strabismus<br />
or anisometropia. There is no single surgical approach to correct<br />
strabismus <strong>of</strong> patients with Möbius sequence, though muscles<br />
recessions and transpositions can be the option. Treatment for<br />
facial nerve palsy involves reconstructive plastic surgery with<br />
muscle transplantation ideally performed in patients just before<br />
they reach school age at 4 or 5 years.<br />
Conclusion: We therefore conclude that the public should be<br />
educated on the potential teratogenic effects <strong>of</strong> misoprostol in<br />
order to eliminate its use as an abortifacient. Awareness about<br />
this syndrome for early diagnosis and treatment <strong>of</strong> the patient is<br />
needed. Parents counseling and education are invaluable.<br />
Key Words: Moebius syndrome, Misoprostol.
PP-47<br />
Strabismus Surgery in a Child with Moebius Syndrome<br />
Maureen M. Resonable, Michelle M. Hernandez<br />
Ospital ng Maynila Medical Center, Philippines<br />
Objective: To report a case <strong>of</strong> Moebius syndrome with surgical<br />
management <strong>of</strong> strabismus.<br />
Methods: This is a case report<br />
Results: This is a case <strong>of</strong> a 9 year old male diagnosed with<br />
Moebius syndrome. The patient presented with loss <strong>of</strong> ocular<br />
abduction, esotropia <strong>of</strong> 65 PD by Krimsky, lagophthalmos, masklike<br />
facies and speech difficulties. Medial rectus recession with<br />
botulinum toxin injection and full tendon transposition <strong>of</strong> vertical<br />
muscles with ciliary sparing, OU was done. Esotropia was<br />
reduced to 15 PD by Krimsky 5 weeks post-operatively with no<br />
hypertropia nor anterior segment ischemia noted. Full cycloplegic<br />
refraction was prescribed to neutralize the residual esotropia.<br />
Conclusion: Moebius syndrome is a rare congenital disorder<br />
characterized by facial diplegia and lateral gaze paralysis. The<br />
management <strong>of</strong> strabismus in patients with Moebius syndrome<br />
is complex and no single surgical approach is successful in all<br />
patients. The family must be counseled prior to surgery to avoid<br />
non-realistic expectations.<br />
Key Words: esotropia, Moebius syndrome, strabismus surgery<br />
PP-48<br />
Prevalence <strong>of</strong> Amblyopia in School Aged Children in<br />
Maybunga Elementary School<br />
Airene M. Oloroso<br />
Rizal Medical Center, Philippines<br />
Objective: Amblyopia is responsible for more unilaterally<br />
reduced vision <strong>of</strong> childhood onset than other causes, with the<br />
prevalence <strong>of</strong> 2-4%. In children, vision impairment can affect<br />
school performance and other functions, such as ability to safely<br />
participate in sports. Strabismus, the most common contributing<br />
factor to amblyopia, can also result in loss <strong>of</strong> stereopsis, leading<br />
to impaired depth perception, as well as teasing and other<br />
psychosocial consequences. Amblyopia is therefore considered<br />
to be a developmental disorder that is most effectively treated<br />
during an early, sensitive period. This understanding has been<br />
one <strong>of</strong> the key justifications for vision screening. The other main<br />
justification for vision screening is that it provides an opportunity<br />
to correct any vision problems and potentially promoting school<br />
performance during an important period <strong>of</strong> social and functional<br />
development.<br />
Methods: This is a prospective study that includes all schoolaged<br />
children <strong>of</strong> Maybunga, Elementary School.<br />
Results: We screened 1050 students <strong>of</strong> Maybunga, Elementary<br />
School. 140 students were refracted using cyclopentolate.<br />
Conclusion: The school doctors or nurse need to be more<br />
diligent in identifying children with problems in vision or alignment<br />
in order to have a proper referral to o ophthalmologist to prevent<br />
or early treatment <strong>of</strong> amblyopia.<br />
PP-49<br />
Self-inflicted, Traumatic Disinsertion <strong>of</strong> the Lateral Rectus:<br />
A Case Report<br />
Patricia Isabel C. Manalastas, Fay Charmaine S. Cruz<br />
University <strong>of</strong> the East Ramon Magsaysay Memorial Medical<br />
Hospital, Philippines<br />
Objective: To present a case <strong>of</strong> a 23-year old male who presented<br />
with acute onset diplopia secondary to a self-inflicted disinsertion<br />
<strong>of</strong> the lateral rectus.<br />
Methods: A case <strong>of</strong> a self-inflicted disinsertion <strong>of</strong> the lateral<br />
rectus will be reviewed. Clinical findings as well as management<br />
<strong>of</strong> the case were compared with those reported in literature.<br />
Results: The ideal management for lost muscle is to retrieve<br />
and re-attach to the original insertion. However, in cases wherein<br />
the muscle is not located, a Hummelsheim procedure with<br />
Foster modification was effective in achieving orthophoria on<br />
primary gaze. The patient’s ability to fuse and early intervention<br />
contributed to the success <strong>of</strong> the surgery.<br />
Conclusion: The case <strong>of</strong> a 23-year old male who presented with<br />
acute onset diplopia secondary to a self-inflicted disinsertion <strong>of</strong> the<br />
lateral rectus was successfully treated by doing a Hummelsheim<br />
procedure with Foster modification.<br />
Key Words: Acute Esotropia, Avulsed conjunctiva, Hummelshei,<br />
Foster modification<br />
Retina and Vitreous<br />
PP-50<br />
Poster Presentations<br />
Neuritis and Neuro-retinitis as Initial Presentations <strong>of</strong> HIV<br />
Elenor Reina S. Aquino, Jessica Marie R. Abaño, Jocelyn Sy<br />
University <strong>of</strong> Santo Tomas Hospital, Philippines<br />
Objective: To describe ocular findings <strong>of</strong> two patients presenting<br />
with neuritis and neuro-retinitis who subsequently tested positive<br />
for HIV.<br />
Methods: This is a report <strong>of</strong> 2 cases.<br />
Results: Case 1 is that <strong>of</strong> an apparently healthy 27 year old male<br />
who consulted because <strong>of</strong> blurring <strong>of</strong> vision. Pertinent findings on<br />
the affected eye were vision <strong>of</strong> 20/30, quiet anterior segment and<br />
a swollen optic nerve with blurred disc margin and surrounding<br />
flame-shaped hemorrhages. Chest X-ray was normal, pure<br />
protein derivative (PPD) was zero and CBC showed leucopenia.<br />
Fluorescein angiography showed optic nerve hyperfluorescence<br />
with vessel leakage and staining. He further disclosed a history<br />
<strong>of</strong> cat scratch. He was diagnosed with probable Batonella<br />
44
Henselae infection and was treated with oral antibiotic with good<br />
response. An HIV screening later revealed positive result. Case<br />
2 is that <strong>of</strong> a 23-year old male who had a history <strong>of</strong> on and <strong>of</strong><br />
fever accompanied by rashes. He consulted because <strong>of</strong> blurring<br />
<strong>of</strong> vision. Pertinent findings on the affected eye were vision <strong>of</strong><br />
20/30, quiet anterior segment and a swollen optic nerve, blurred<br />
disc margin with surrounding flame-shaped hemorrhages and<br />
exudates involving the papillo-macular area. Chest X-ray was<br />
normal, PPD was negative and CBC showed leucocytosis. CMV<br />
antigenemia was elevated. He was diagnosed to have CMV<br />
retinitis and was treated accordingly. An HIV screening later<br />
revealed positive result<br />
Conclusion: With the increasing incidence <strong>of</strong> HIV/AIDS in the<br />
Philippines, HIV-associated ocular infections should therefore be<br />
considered as differentials in patients with uveitis presenting as<br />
neuritis or neuro-retinitis.<br />
Key Words: HIV, Neuroretinitis, Cat-scratch disease, Bartonella<br />
henselae, CMV<br />
PP-51<br />
Bilateral Serous Retinal Detachment in Toxemia <strong>of</strong><br />
Pregnancy: A Case Series<br />
Mayjane Joan G. Tumulak, Jocelyn Sy<br />
DOH Eye Center East Avenue Medical Center, Philippines<br />
Objective: To describe a series <strong>of</strong> gravid patients with toxemia<br />
<strong>of</strong> pregnancy presenting with bilateral retinal detachment.<br />
To describe the clinical course and management <strong>of</strong> retinal<br />
detachment in patients with preeclampsia, eclampsia and HELLP<br />
syndrome<br />
Method: This is a case series <strong>of</strong> three pregnancy induced<br />
hypertensive patients (1 eclampsia, 1 preeclampsia, 1<br />
preeclampsia with HELLP syndrome) at the East Avenue Medical<br />
Center Department <strong>of</strong> Obstetrics delivery room who complained<br />
<strong>of</strong> blurring <strong>of</strong> vision, which on fundus examination revealed<br />
bilateral serous retinal detachment. Baseline VA: CF to HM in<br />
both eyes. All patients underwent emergency caesarean section<br />
and all eyes were managed clinically. One case had subtenon<br />
triamcinolone, acetazolamide and hypertension control and the 2<br />
cases had hypertension control only. Fundus photos were taken<br />
to monitor reattachment.<br />
Results: After 1 week postpartum, all eyes had improvement<br />
<strong>of</strong> vision at 20/32 with note <strong>of</strong> resorption <strong>of</strong> the bilateral retinal<br />
detachment, 2 cases had stabilization <strong>of</strong> the systemic disease,<br />
however 1 case had poor hypertension control whose eyes had<br />
bilateral central retinal vein occlusion.<br />
Conclusion: Early assessment <strong>of</strong> blurring <strong>of</strong> vision in pregnant<br />
patients should be warranted for this may give a clue for maternal<br />
and fetal prognosis. Although bilateral retinal detachment in this<br />
case is managed clinically, this will assure the patient that there is<br />
good visual recovery. The need for an eye consult in all patients<br />
with pregnancy induced hypertension is strongly recommended<br />
especially in a community based set-up.<br />
45<br />
Poster Presentations<br />
Key Words: Bilateral serous retinal detachment, toxemia in<br />
pregnancy, preeclampsia, eclampsia, HELLP syndrome<br />
PP-52<br />
Choroidal Hemangioma: A Case Report<br />
Jan Carlo Y. Alegre, Jocelyn Sy<br />
DOH Eye Center East Avenue Medical Center, Philippines<br />
Objective: To report investigative and treatment measures in a<br />
patient with choroidal hemangioma.<br />
Methods: This is a case report.<br />
Results: A 15 year old female complaining <strong>of</strong> progressive<br />
blurring <strong>of</strong> vision <strong>of</strong> the right eye for two years duration. On eye<br />
examination, visual acuity was 20/200 over the right eye with<br />
positive RAPD and 30 degrees exotropia. Fundus examination<br />
showed a reddish-orange mass with overlying exudative retinal<br />
detachment, around two disc diameters temporal to the optic<br />
nerve <strong>of</strong> the right eye. Fundus photo, orbital MRI with contrast,<br />
T1/T2 weighted, fluorescein angiography and macular OCT were<br />
requested. Transpupillary Thermotherapy was then initiated<br />
followed by anti-VEGF treatment.<br />
Conclusion: Choroidal hemangiomas are rare, benign vascular<br />
tumors, which can be mistaken for other malignant intraocular<br />
tumors. With the use new technologies, confusion regarding the<br />
diagnosis can be minimized. Transpupillary Thermotherapy is still<br />
the gold standard for treatment however, anti-VEGF medications<br />
can be an adjunct to therapy in order to provide better resolution<br />
<strong>of</strong> symptoms.<br />
Key Words: anti-VEGF, choroidal hemangioma, intraocular<br />
tumor, transpupillary thermotherapy<br />
PP-53<br />
Central Retinal Artery Occlusion in the Young<br />
Erica Blanca Daquil<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
Objectives: To present a rare case <strong>of</strong> Central Retinal Artery<br />
Occlusion (CRAO) in a 15 year old young, Filipino female.<br />
Methods: This is an emergency room case <strong>of</strong> a young female<br />
with a complaint <strong>of</strong> sudden blurring <strong>of</strong> vision in the right eye which<br />
was thoroughly investigated.<br />
Results: This is a case report <strong>of</strong> a 15 year old, Filipino, female<br />
which developed a Central Retinal Artery Occlusion <strong>of</strong> the right<br />
eye. The symptoms started a few hours upon waking up where<br />
patient had sudden blurring <strong>of</strong> her vision. The fundus exam<br />
revealed a pale retina with a cherry red spot in the macula and<br />
noted an obstruction in the inferior retinal vessel. A prompt<br />
emergency treatment for CRAO was administered upon note <strong>of</strong> the<br />
findings. Further laboratory work up was done and concomitantly<br />
managed with the Pediatric Department to investigate the cause<br />
and for proper evaluation and treatment administration. Persistent
investigation resulted into the diagnosis <strong>of</strong> Rheumatic Heart<br />
Disease in the patient in which clenched the probable cause <strong>of</strong><br />
the obstruction.<br />
Conclusion: This report shows a rare case <strong>of</strong> CRAO in the young<br />
wherein the retinal obstructive symptoms preceded the systemic<br />
symptoms and finding <strong>of</strong> the cardiac problem. The patient was<br />
for a long time asymptomatic systemically until the manifestation<br />
<strong>of</strong> the sudden blurring <strong>of</strong> vision which lead to the finding <strong>of</strong> the<br />
presence <strong>of</strong> the cardiac disease after thorough investigation.<br />
This prompt evaluation has helped the clinicians to properly treat<br />
and more importantly minimize additional systemic and ocular<br />
morbidity in this young individual.<br />
Key Words: Central Retinal Artery Occlusion, Cherry Red Spot,<br />
Rheumatic Heart Disease<br />
PP-54<br />
Best’s Vitelliform Macular Dystrophy with Normal EOG:<br />
A Case Report<br />
Nikki Doreen Angbue Te<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
Objective: To describe a case <strong>of</strong> Best’s Disease with normal<br />
EOG.<br />
Methods: This is a case report <strong>of</strong> a 14 year old female with a 1<br />
year history <strong>of</strong> central scotoma on the right eye.<br />
Results: Vision on the right eye was 20/100, 20/20 on the left<br />
eye. Fundoscopy <strong>of</strong> the right eye showed a round retinal elevation<br />
at the center <strong>of</strong> the macula with vitelliform changes inferiorly and<br />
subretinal hemorrhage superiorly. The left eye likewise showed<br />
retinal elevation at the macula with vitelliform changes. Fluorescein<br />
angiography <strong>of</strong> the right eye showed a hyperfluorescent patch<br />
at the macula with areas <strong>of</strong> blocked fluorescence. The left eye<br />
similarly revealed a hyperfluorescent patch. ICG <strong>of</strong> both eyes<br />
showed hyp<strong>of</strong>luorescent patches which corresponds to the<br />
vitelliform changes with areas <strong>of</strong> hyperfluorescence in the right<br />
eye. ERG and EOG were normal. Patient subsequently underwent<br />
PDT on the right eye with improvement <strong>of</strong> vision.<br />
Conclusion: A normal EOG light rise is uncommon in Best’s<br />
disease. However, this does not rule out the diagnosis.<br />
Key Words: Best Vitelliform Maculary Dystrophy, Best disease,<br />
Normal EOG, Best disease, Best Vitelliform Maculary Dystrophy<br />
PP-55<br />
Neovascular Glaucoma and Exudative Retinal Detachment in<br />
a Young Male: A Case Report<br />
Mark Angelo B. Hosaka<br />
St. Luke’s Medical Center, International Eye Institute, Philippines<br />
Objective: The purpose <strong>of</strong> this report is to present a case <strong>of</strong><br />
a retinal detachment which eventually leads to neovascular<br />
glaucoma. Highlighting the clinical course, evaluation and<br />
management <strong>of</strong> the case.<br />
Methods: A case report series<br />
Results: B-scan ultrasonography showed a dome shaped<br />
elevation connected to the optic nerve. Hyperechoic subretinal<br />
punctate densities with after movement were seen. Moderate<br />
amplitude echo was noted in the midvitreous cavity. Fundus<br />
photo <strong>of</strong> the left eye showed total bullous retinal detachment with<br />
extensive exudates and hemorrhage. Patient had undergone<br />
diode cyclophotocoagulation which relieves the patient’s pain and<br />
reduces the patient’s IOP.<br />
Conclusions: Patient was diagnosed with Neovascular<br />
Glaucoma and Exudative Detachment secondary to Coat’s<br />
Disease. Coats disease is a distinct clinical entity characterized<br />
by idiopathic retinal telangiectasia with subsequent sequelae<br />
<strong>of</strong> exudative retinal exudation and if left untreated can cause<br />
neovascular glaucoma. The clinician should follow strict criteria<br />
as stated by Shields in making the diagnosis, to avoid confusing<br />
Coats disease with other forms <strong>of</strong> exudative retinopathy that have<br />
<strong>of</strong>ten been called Coats disease erroneously. The differential<br />
diagnosis <strong>of</strong> Coats disease includes retinoblastoma and many<br />
other conditions that produce exudative retinopathy, particularly<br />
in children.<br />
Key Words: Retina, Neovascular Glaucoma, Pediatric Patients<br />
PP-56<br />
Poster Presentations<br />
Treatment <strong>of</strong> Polypoidal Choroidal Vasculopathy<br />
Paul Samuel Del Mundo, Johanna T. Cervantes<br />
Pearl Tamesis-Villalon<br />
St. Luke’s Medical Center International Eye Institute, Philippines<br />
Objective: To describe new modalities in the treatment <strong>of</strong><br />
Polypoidal Choroidal Vasculopathy (PCV).<br />
Methods: This is a retrospective, non-comparative case series <strong>of</strong><br />
3 patients with PCV who were treated with newer methods.<br />
Results: All three patients were diagnosed to have PCV causing<br />
blurred vision. All patients were treated with either focal laser,<br />
photodynamic therapy with Verteporfin (PDT), intravitreal<br />
Ranibizumab injection (IVR) or both PDT+IVR. Treatment showed<br />
improvement in the visual acuity and resolution <strong>of</strong> the PCV with<br />
PDT + IVR and IVR alone.<br />
Conclusion: New treatment modalities must be considered in the<br />
treatment <strong>of</strong> PCV.<br />
Key Words: Polypoidal Choroidal Vasculopathy, Photodynamic<br />
Therapy with Verteporfin<br />
46
Poster Presentations<br />
PP-57<br />
Retinopathy <strong>of</strong> Prematurity Screening in a Tertiary<br />
Care Center: Incidence and Percentage <strong>of</strong> Referrals by<br />
Neonatologists<br />
Anna Karina D. Leopando<br />
The Medical City, Philippines<br />
Objective: To determine the percentage <strong>of</strong> premature neonates<br />
referred for retinopathy <strong>of</strong>m prematurity (ROP) screening among<br />
admitted infants in a Neonatal Intensive care Unit (NICU) and<br />
to identify the incidence <strong>of</strong> ROP in a tertiary care center in a<br />
developing country.<br />
Methods: A retrospective case control observational study on<br />
preterm infants admitted to the NICU <strong>of</strong> a tertiary hospital between<br />
2009 to 2011, with either birthweight
Uveitis and Intraocular Inflammation<br />
PP-60<br />
Vogt-Koyanagi-Harada Syndrome: A Case Report<br />
Anna Francesca B. Bayrante, Jessica Marie R. Abaño<br />
DOH Eye Center, East Avenue Medical Center, Philippines<br />
Objective: A case <strong>of</strong> Vogt-Koyanagi-Harada Syndrome, from<br />
diagnosis to treatment, is presented.<br />
Method: A case report <strong>of</strong> a 28 year old Filipino female<br />
who presented with bilateral blurring <strong>of</strong> vision, associated<br />
with dermatological and neurosensory symptoms, with the<br />
development <strong>of</strong> serous retinal detachment in both eyes.<br />
Result: A diagnosis <strong>of</strong> Vogt-Koyanagi-Harada Disease (VKH) was<br />
made. Treatment with high-dose intravenous and oral steroids<br />
was initiated with concurrent optical coherence tomography<br />
studies <strong>of</strong> the macula. Improvement in visual acuity and resolution<br />
<strong>of</strong> subretinal fluid on serial OCT scans was observed within<br />
2 months <strong>of</strong> treatment. Methotrexate was likewise started to<br />
facilitate tapering <strong>of</strong> the oral steroids.<br />
Conclusion: The case demonstrated that immediate diagnosis<br />
and treatment, guided by standard drug protocols, and close<br />
monitoring <strong>of</strong> patients with the aid <strong>of</strong> optical diagnostic modalities,<br />
are essential in controlling and ceasing the destructive<br />
inflammatory process in VKH, resulting in good visual outcomes.<br />
Key Words: Vogt-Koyanagi-Harada, methotrexate,methylprednisolone,<br />
exudative retinal detachment<br />
PP-61<br />
Ocular Involvement in Adamantiades-Beh’et Disease (ABD)<br />
Aileen Viguilla, Egidio Jose S. Fortuna<br />
The Medical City, Philippines<br />
Objective: To discuss the clinical history, diagnosis, associated<br />
ocular manifestations, treatment and long-term visual morbidity <strong>of</strong><br />
Adamantiades-Beh’et Disease (ABD).<br />
Methods: This is a case report.<br />
Results: We reviewed a case <strong>of</strong> a 31 year old Filipino male who<br />
presented with intermittent bilateral blurring <strong>of</strong> vision associated<br />
with recurrent oral ulcers. Upon ophthalmologic evaluation,<br />
visual acuity was counting fingers with anterior and vitreous<br />
inflammation, and bilateral vasculitis on both eyes. Fluorescein<br />
angiogram showed consistent findings <strong>of</strong> bilateral vasculitis. He<br />
underwent two sessions <strong>of</strong> cyclophosphamide infusion and was<br />
maintained on oral prednisone and azathioprine. Visual acuity<br />
gradually improved to 20/50 (right eye) and 20/25 (left eye). There<br />
was note <strong>of</strong> resolution <strong>of</strong> inflammation and vasculitis. Optimal<br />
dose <strong>of</strong> prednisone was noted to be at 50mg. He was lost to<br />
follow-up for two months, and upon consult, visual acuity was at<br />
20/150 (right eye) and 20/400 (left eye), with new retinal lesions<br />
Poster Presentations<br />
noted. He underwent 3rd infusion <strong>of</strong> cyclophosphamide. Visual<br />
acuity improved and the retinal lesions resolved. Oral prednisone<br />
and azathioprine were maintained.<br />
Conclusion: Adamantiades- Beh’et disease (ABD) is a clinical<br />
diagnosis that relies mainly on the history and recognition <strong>of</strong><br />
signs and symptoms. For ophthalmologists, the ultimate goal for<br />
patients with the disease is to preserve vision through control <strong>of</strong><br />
inflammation, prevention <strong>of</strong> recurrent attacks and early detection<br />
<strong>of</strong> retinal involvement that may lead to blindness if left untreated.<br />
Treatment is individualized and adjusted according to the patient’s<br />
need. Close follow-up is warranted to prevent further morbidity.<br />
Key Words: Adamantiades-Beh’et disease, ocular inflammation,<br />
steroids, retinal vasculitis, oral ulcers, blurring <strong>of</strong> vision,<br />
cyclophosphamide, blurring <strong>of</strong> vision, ocular inflammation<br />
48
Notes<br />
49
Notes<br />
50
Notes<br />
51
ACS <strong>2012</strong> EFOCAL POINT <strong>PAO</strong> <strong>2012</strong> PJO