Company Presentation January 2013 - Epigenomics AG

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Contents � Epigenomics overview � Epi proColon • Unmet need & opportunity • Characteristics & clinical data • US strategy � Epi proLung & future product opportunities � Summary � Appendix 6 | January 2013
Colorectal Cancer (CRC) Screening Saves Lives and Money; However 1 in 3 Screening Eligible Adults are not Screened CRC Screening Saves Lives and Money… � CRC is the second largest cancer killer in the US 7 | January 2013 140,000 new cases 50,000 deaths 1 � CRC is treatable if detected early enough � 5-year survival for diagnosed and treated Stage I/II CRC: 90% � Estimated US direct medical cost of CRC care in 2010 was $14 billion …However a Substantial Percentage of Citizens Remains Unscreened For CRC Colonoscopy 35 million U.S. citizens are unscreened Stool based tests Key challenge: non-compliance to existing stool-based or invasive (colonoscopy) CRC screening options 1) American Cancer Society.: Cancer Facts and Figures 2012. Atlanta, Ga: American Cancer Society, 2012. Graph: Centers for Disease Control. "Vital signs: Colorectal cancer screening, incidence, and mortality---United States, 2002-2010. " MMWR Morb. Mortal. Weekly Report. 2011, 60(26):884-889.
Page 1 and 2: Epigenomics AG Corporate Presentati
Page 3 and 4: Contents � Epigenomics overview
Page 5: Key Financials 9M 2012 � Tightly
Page 9 and 10: Blood-based Screening is Widely Acc
Page 11 and 12: Methylated Septin9 is a Suitable Ma
Page 13 and 14: Epi proColon®: One Assay - One Mar
Page 15 and 16: Fecal Immunochemical Test (FIT) Com
Page 17 and 18: Comparison Study Top Line Data: Sen
Page 19 and 20: Comparison Study Top Line Data: Det
Page 21 and 22: FDA Submission Status: Completed in
Page 23 and 24: Expected US Product Launch of Epi p
Page 25 and 26: Epi proLung® - Market Introduction
Page 29 and 30: Why Invest in Epigenomics.... 29 |
Page 33 and 34: Septin9 Tests: Continious Improveme

Company Presentation January 2013 - Epigenomics AG

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