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The Pressure Cooker: Hypertension and Hemorrhagic Stroke

The Pressure Cooker: Hypertension and Hemorrhagic Stroke

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<strong>Hypertension</strong> <strong>and</strong> the Vessel<br />

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High intralumen pressures alter the endothelium<br />

<strong>and</strong> smooth muscle in intracerebral arteries<br />

Degenerative changes in the smooth muscle<br />

predisposes for ICH<br />

Endothelial damage can lead to thrombi formation<br />

<strong>and</strong> ischemic lesions<br />

Increased endothelial stress can increase the<br />

permeability of the blood brain barrier

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