Directory of Cyclotrons used for Radionuclide Production in Member ...

IAEA-DCRP/2006
Directory of Cyclotrons used for
Radionuclide Production in
Member States
2006 Update
October 2006

The originating Section of this publication in the IAEA was:
Industrial Applications and Chemistry Section
International Atomic Energy Agency
Wagramer Strasse 5
P.O. Box 100
A-1400 Vienna, Austria
DIRECTORY OF CYCLOTRONS USED FOR
RADIONUCLIDE PRODUCTION IN MEMBER STATES:
2006 UPDATE
IAEA, VIENNA, 2006
IAEA-DCRP/2006
ISBN 92-0-111506-7
© IAEA, 2006
Printed by the IAEA in Austria
October 2006

FOREWORD
The present directory of cyclotron facilities used for the production of radionuclides in Member
States is an update of the one compiled by the International Atomic Energy Agency (IAEA) in late
2001 and published in 2002. This directory was prepared through information collected by
questionnaires that the IAEA sent to known institutions operating cyclotrons for radionuclide
production. Technical as well as administrative data supplied to the IAEA as of November 2005 were
taken into account.
The directory is considered to include most of the cyclotrons of the world that are used at least
partially for radionuclide production. There are 262 entries for cyclotrons operating in 39 Member
States of the IAEA. This is an increase of 7% over the 246 reported in the 2002 cyclotron directory.
This can be compared to the 350 or so cyclotrons believed to be presently operating in the world,
which are involved in some aspects of radionuclide production. The increase has been in the number
of cyclotrons in developed countries, but even more so in the developing countries. The increase in
number during the last four years was driven by several factors, i.e. advent of advances in medical
imaging, introduction of compact, user friendly medical cyclotron, and a recent decision that costs for
15 O-oxygen position emission tomography (PET) studies in Japan and 18 F-FDG PET studies in
Germany and the United States of America are eligible for reimbursement by government or health
insurance companies. There is no doubt that the fastest growing segment of the market is in the
commercial distribution of FDG to local hospitals.
The IAEA is promoting cyclotron technology as applied to nuclear medicine. Requests for
cyclotron technology is steadily increasing; many developing Member States are interested in this
technology. There is need to stimulate, build and maintain consulting capability in interested
developing Member States. There are good reasons to believe that the number of cyclotron facilities
dedicated to the production of PET tracers will continue to grow in the near future, so the need to
further update the directory will be assessed in due course, depending on comments and suggestions
receiving from users of the directory. This directory will help decision makers and specialists in
Member States to draft mid and long term strategies regarding the implementation of cyclotron
technology for radioisotope production and their medical applications, as well as for selection of the
most suitable alternative.
The IAEA wishes to thank D.J. Schlyer of the Brookhaven National Laboratories, USA, for his
analysis of the data. The IAEA officer responsible for the compilation of the directory was M. Haji-
Saeid of the Division of Physical and Chemical Sciences.

EDITORIAL NOTE
This CD-ROM has been prepared from the original material as submitted by contributors. Neither the
IAEA nor its Member States assume any responsibility for the information contained on this CD-
ROM.
The use of particular designations of countries or territories does not imply any judgement by the
publisher, the IAEA, as to the legal status of such countries or territories, of their authorities and
institutions or of the delimitation of their boundaries.
The mention of names of specific companies or products (whether or not indicated as registered) does
not imply any intention to infringe proprietary rights, nor should it be construed as an endorsement
or recommendation on the part of the IAEA.

CONTENTS
SUMMARY ............................................................................................................................................ 1
1. Argentina......................................................................................................................................... 7
2. Australia........................................................................................................................................ 11
3. Austria........................................................................................................................................... 17
4. Belgium......................................................................................................................................... 21
5. Brazil............................................................................................................................................. 37
6. Canada........................................................................................................................................... 41
7. China............................................................................................................................................. 59
8. Czech Republic ............................................................................................................................. 77
9. Denmark........................................................................................................................................ 81
10. Egypt........................................................................................................................................... 85
11. Finland ........................................................................................................................................ 87
12. France.......................................................................................................................................... 95
13. Germany.................................................................................................................................... 107
14. Hungary..................................................................................................................................... 153
15. India .......................................................................................................................................... 155
16. Indonesia................................................................................................................................... 159
17. Iran, Islamic Republic of........................................................................................................... 161
18. Israel.......................................................................................................................................... 163
19. Italy ........................................................................................................................................... 167
20. Japan ......................................................................................................................................... 193
21. Kazakhstan................................................................................................................................ 265
22. Korea, Republic of.................................................................................................................... 267
23. Mexico ...................................................................................................................................... 297
24. Netherlands ............................................................................................................................... 299
25. Norway...................................................................................................................................... 319
26. Philippines................................................................................................................................. 321
27. Poland ....................................................................................................................................... 323
28. Romania .................................................................................................................................... 327
29. Russian Federation.................................................................................................................... 329
30. Saudi Arabia.............................................................................................................................. 347
31. Slovakia..................................................................................................................................... 349
32. South Africa.............................................................................................................................. 351
33. Spain ......................................................................................................................................... 353
34. Sweden...................................................................................................................................... 363
35. Switzerland ............................................................................................................................... 365
36. Syrian Arab Republic................................................................................................................ 371
37. Turkey....................................................................................................................................... 373
38. United Kingdom........................................................................................................................ 377
39. United States of America .......................................................................................................... 391

SUMMARY
The directory of cyclotrons used for radionuclide production in Member States contains
technical, utilization and administrative information supplied to the IAEA as of November 2005. It
was prepared through information collected by questionnaires sent to institutions that either have a
cyclotron or were identified to be in the process of installing a cyclotron.
Included in the directory are a significant fraction of the cyclotrons of the world that are used at
least in part for radionuclide production. If replies were not received from institutions, it was assumed
that the cyclotron is still being used for similar tasks as it was at the time of the last survey. Some
institutions reported that older cyclotrons had been shut down and replaced with newer cyclotrons. The
questionnaire was, in general, not completed by institutions that have cyclotrons dedicated to physics
and/or material science activities. Certain of the institutions constructing superconducting cyclotrons
for medical and nuclear physics applications responded even though they are not yet involved in
radionuclide production initiatives.
The directory is organized alphabetically by Member States and by institutes. There are
individual entries for each cyclotron even for institutions having more than one cyclotron. The names,
title/position of the persons listed in position in the entries for individual countries were taken directly
from the answers in the questionnaires.
There are 262 entries for cyclotrons operating in 39 Member States of the IAEA. This is an
increase of 7% over the 246 reported in the 2002 cyclotron directory. This can be compared to the 350
or so cyclotrons believed to be presently operating in the world, which are involved in some aspects of
radionuclide production. The increase has been in the number of cyclotrons in developed countries, but
even more so in the developing countries. Large concentrations of cyclotrons for radionuclide
production are located in the United States of America, Japan and Germany. The largest number of
cyclotrons for a single country is in the United States of America. However, taken collectively there
are more cyclotrons located in the European Union countries that are used for medical radionuclide
production.
The number of institutions which distribute radiopharmaceuticals and 18 F-FDG, in particular, is
significant and growing. In this sample, 75% of the cyclotrons are being used to produce FDG, either
for internal use or for distribution. This is certainly an underestimate as the commercial suppliers are
under represented in this survey.
The expansion in the number of cyclotrons during the last 10 years has been driven by the
advent of advances in medical imaging instrumentation (PET, SPECT and more recently PET/CT);
introduction of user friendly compact medical cyclotrons from several companies that manufacture
cyclotrons; and recent decisions that some PET radiopharmaceuticals are eligible for reimbursement
by government or insurance companies. There is no doubt that the fastest growing segment of the
market is in the commercial distribution of 18 F-FDG to local hospitals. Many centers have begun
distributing FDG and at present at least 36% of the centers producing FDG are distributing it. Again
this is a lower limit rather than an accurate assessment. The satellite approach is cost-effective
because it is not necessary for every medical imaging centre to own a cyclotron as a source of shortlived
radiopharmaceuticals. 18 F-FDG is gaining widespread clinical acceptance for a variety of disease
states.
The number of types of cyclotrons available commercially is quite large and growing. The
energies range from a few MeV for only PET isotope production to a few hundreds MeV for proton
therapy or production of radioisotopes requiring these high energies. The beam currents range upwards
from 40 µ to over 1 mA. The characteristics of the machines available for commercial acquisition are
shown in Table I.
1

TABLE I. CHARACTERISTICS OF COMMERCIAL CYCLOTRONS
Company Model Description Oper. Plan
CTI, Inc. RDS 111 11 MeV H - , 60µA 44 10
RDS 112 11 MeV H - , 60µA 30
Ebco Technologies TR 14 11-14 MeV H - , 100µA 2
TR 19 14-19 MeV H - , 160µA 2
TR 19/9 19 MeV H - , 9 MeV D - , 160µA 1 3
TR30 30 MeV H - , 100µA 2
TR30/15 30 MeV H - , 15 MeV D - , 160µA 1
D.V. Efremov Institute MGC-20 18 MeV H - , 10 MeV D - , 160µA 4 2
General Electric MiniTrace 9.6 MeV H - , 50µA 2
PETrace 16.5 MeV H - , 8.6 MeV D - , 80µA 16
Ion Beam Applications Cyclone 3 3.8 MeV D - , 60µA 2
Cyclone 10/5 10 MeV H - , 5 MeV D - , 60µA 3
Cyclone 18/9 18 MeV H - , 9 MeV D - , 80µA 15 5
Cyclone 18+ 18 MeV H - , 80µA 1
Cyclone 30 30 MeV H - , 15 MeV D - , 400µA 16 2
Cyclone 235 240 MeV H - 1
Japan Steel Works BC168 16 MeV H + , 8 MeV D + , 50µA 2
BC1710 17 MeV H + , 10 MeV D + , 60µA 7
BC2010N 20 MeV H - , 10 MeV D - , 60µA 2
BC2211 22 MeV H + , 11 MeV D + , 60µA 1
BC3015 30 MeV H + , 15 MeV D + , 60µA 1
Oxford Instrument Co. OSCAR 12 12 MeV H - , 60µA 5
Scanditronix Medical AB MC17 17.2 MeV H + , 8.3 MeV D + , 60µA 13
12 MeV 3 He ++ , 16.5 4 He ++ , 60µA
MC30 30 MeV H + , 15 MeV D + , 60µA
MC32NI 15-32 MeV H - , 8-16 MeV D - , 60µA 3
11-23 MeV 3 He ++ , 15-31 4 He ++ , 60µA
MC40 10-40 MeV H + , 5-20 MeV D + , 60µA 6
13-53 MeV 3 He ++ , 10-40 4 He ++ , 60µA
MC50 18-52 MeV H + , 9-25 MeV D + , 60µA 1
24-67 MeV 3 He ++ , 18-50 4 He ++ , 60µA
MC60 50 MeV H + , 60µA 1
K130 6-90 MeV H - , 10-65 MeV D - , 60µA
16-173 MeV 3 He ++ , 20-130 4 He ++
Sumitomo Heavy Industries CYPRIS 325 16 MeV H + , 8 MeV D + , 60µA 1
CYPRIS 370 16 MeV H + , 10 MeV D + , 60µA 4
HM 18 18 MeV H - , 10 MeV D - , 60µA 7
HM 12 12 MeV H - , 6 MeV D - , 60µA 1
480 AVF 30 MeV H + , 60µA 1
AVF 680 40 MeV H + , 60µA 1
AVF 715 50 MeV H + , 60µA
AVF 750 70 MeV H + , 60µA 1
AVF 930 90 MeV H + , 60µA 2
AVF 1000 80 MeV H + , 60µA
Ring Cyclotron 400 400 MeV H + (K=400), 60µA 1
Ring Cyclotron 540 240 MeV H + (K=540), 60µA 1
C235 240 MeV H - , 60µA 1
KIRAMS Kirams-13 13 MeV H + , 100 µA 3
2

Of the respondents to the survey, the number of existing cyclotrons broken down by energy
level is given in Fig. 1.
Number of Cyclotrons
180
160
140
120
100
80
60
40
20
0
100 MeV
Energy Distribution
FIG. 1. Distribution of proton energies as reported by respondents to the IAEA survey.
The preponderance of low energy cyclotrons can be clearly seen from the distribution which is
very similar to the distribution from the 2002 edition of the directory. Another interesting aspect is the
distribution of time being devoted to radioisotope production. This distribution is shown in Figure 2.
Number of Instutions
80
70
60
50
40
30
20
10
0
100 hrs
Radioisotope Production Hours per week
FIG. 2. Distribution of hours of radioisotope production from the respondents to the IAEA survey.
3

One interesting aspect of this distribution is that many institutions are spending a very small
fraction of the available time in radioisotope production. The cyclotron is idle for a significant fraction
of the week. This implies that the cyclotron is not the slow step in clinical applications and that a
single cyclotron can support several PET or PET/CT cameras.
The other interesting trend is in the compounds that are being synthesized with these
radioisotopes. A graph of the number of centres that responded synthesizing these compounds is given
in Fig. 3.
Number of Instutions
250
200
150
100
50
0
FDG FLT FDOPA Methonine Ammonia Water
Compound
FIG. 3. Number of reporting institutions that use a particular compound.
This figure clearly shows that 18 F-FDG is the most widely produced compound at cyclotron
facilities world wide. It is now used in many applications in diagnostic nuclear medicine.
TABLE II. EXPECTED PRODUCTION YIELDS (MCI) OF SYNTHETIC PRECURSORS OF PET
RADIOPHARMACEUTICALS WITH SELECTED PROTON AND DEUTERON ENERGIES AND
IRRADIATION AT 20 TO 35 ΜA AS RECOMMENDED BY THE MANUFACTURER OF VARIOUS
CYCLOTRONS.
Precursor 12 MeV p only 10 MeV p + 5 MeV d 18 MeV p + 9 MeV d
11 CO2 1500 1000 2800
11 CO 1000 350 1400
11 CO 1250 350 700
11 CO 750 250 1200
13 NH3 200 100 450
15 O2 1000 >150/min. 1200
15 OC 500 >75/min. 700
15 OCO 500 >150/min. 700
15 OH2 750 200 1000
18 F - 700 >500 800
18 FF 300
4

One of the areas of current research is on the development of very high current targets that can
produce several curies of fluorine-18 for synthesis of 18 F-FDG. This type of target is advantageous for
production facilities where distribution of 18 F-FDG is being carried out on a routine basis.
5

1. ARGENTINA
2005 COUNTRY: ARGENTINA ARG-1
[1] INSTITUTE: Comisión Nacional de Energia Atómica (CNEA)
Avenida del Libertador 8250
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
[3]
OTHER SENIOR STAFF:
NAME/POSITION
TYPE OF
Isochronous,
CYCLOTRON: negative ion
MANUFACTURER: The Cyclotron
Corporation
MODEL: CP - 42
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
1429 Buenos Aires
+54 11 4379 8250
rocco@cae.cnea.gov.ar
+54 11 4480 0615
Mr. Carmelo Rocco
Head of the Facility
Mr. Ortega Daniel, in charge of Operation and Maintenance
Mr. Guevara Ernesto, in charge of Radiochemistry
YEAR OF:
(I) INSTALLATION:
1994
(II) UPGRADE: Beam current increase
Dual Beams
Beam energies (MeV) 25/42 Yes No
Maximum beam available (µA) 150
Typical beam employed (µA) 100
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research maintenance applications
29 22 - 7 -
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
123 123 67 111
I, I iodide and other compounds, Ga, In
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s and how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals
carried out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
Number
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
71

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
2
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2?
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18 O (p, n) 18 F 25 95 1.7 45 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name Yield on batch Frequency of
Used on site Distribution/ Price/
(list)
(GBq) production
Sales
GBq
18
FDG 15 4 weekly Yes No Yes No U$S 392
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name Yield on batch Frequency of Used on site Distribution/ Price
(list)
(GBq) production
Sales
/GBq
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield
on batch, GBq
Frequency of
production
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
OTHER ISOTOPES PRODUCED
Typical yield on batch
(GBq)
Nuclear reaction used Distribution/
Sales
Yes No
Yes No
Yes No
Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
Name Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq) production
Sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl 37 2 monthly Yes No Yes No US$ 324
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being
produced)
The production of high purity 123 I is a project that was carried out under the IAEA’s Technical Co-operation
Programme (ARG/4/085). The IAEA supported the CNEA efforts to set up required facilities including different
system provision of expert and personnel training.
8

2005 COUNTRY: ARGENTINA ARG-2
[1] INSTITUTE: Fundación Escuela de Medicina Nuclear
Garibaldi 405, CP 5500
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Mendoza 1429
+54 261 4201 615 ( 1 ext. 564; 2 ext. 562; 3 ext. 508)
enoya@fucsmen.edu.ar
+54 261 4203 288
Ing. Enrique R. Noya
Electronic Engineer – Head of Operation and Maintenance
Dr. Fernando Spigatin 2 , Head of Radiochemical Laboratory
Ing. Norma Acosta 3 , Head of Radiological Security
YEAR OF:
CYCLOTRON:
Negative ion hospital
cyclotron
(I) INSTALLATION
1997
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
This cyclotron is not self-shielded. This is installed inside a bunker. All the support equipment is located in
different rooms.
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 50
Typical beam employed (µA) 20-40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
10 8 2 3
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
15 11
O, C
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
511 KeV coincidence 1
Gamma camera 1
Single photon tomography (SPET) 1
Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
93

4
18F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 20 >97 0.330 100 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of
(list)
(GBq)
production
Used on site Distribution/sales Price/
GBq
18 FDG 10 5/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 4 6/week p+ H20 Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being produced)
10
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2. AUSTRALIA
2005 COUNTRY: AUSTRALIA AUL-1
[1] INSTITUTE: Austin and Repatriation Medical Centre
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
Studley Road, Heidelberg, VIC 3084
+61 3 9496 3995
htd@austin.unimelb.edu.au
+61 3 9496 5892
Dr. Henri Tochon-Danguy
Senior Radiochemist
Dr. John Sachinidis, Radiochemist
Dr. Uwe Ackermann, Radiochemist
Mr. Stan Poniger, Cyclotron/Robotic Engineer
YEAR OF:
1992
CYCLOTRON:
Negative ion
accelerator
(I) INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE: 1996 (new sources)
MODEL: Cyclone 10/5 2001 (remote start-up &
control)
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 10 5 Yes No
Maximum beam available (µA) 50 20
Typical beam employed (µA) 25 8
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
25 25 1 4
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
124 I,
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Number
Single photon tomography (SPET)
Positron emission tomography (PET)
4
– Clinical
– Small animal
– Plant biochemistry
2
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
115

6
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 37 90 1 200 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
Sales
18
FDG 24 7/week Yes No Yes No
18
F MISO 2 1/week Yes No Yes No
18
FLT 2 2/month Yes No Yes No
18 FA85380 2 1/week Yes No Yes No
11 C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq) production
Sales
PIB 2 2/week Yes No Yes No
SCH23390 2 1/month Yes No Yes No
Ro151788 2 2/month Yes No Yes No
Choline 2 2/month Yes No Yes No
PK11195 2 2/month Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
Sales
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 1/min 1/week
14 15
N[d, n] O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
Sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being produced)
12
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: AUSTRALIA AUL-2
[1] INSTITUTE: Australian Nuclear Science & Technology Organization
(ANSTO)
Radiopharmaceutical Division
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
New Illawarra Road
+61 2 9717 9079
stuart.carr@ansto.gov.au
POSITION:
Dr. S. Carr
Director, Radiopharmaceuticals
OTHER SENIOR STAFF:
NAME/POSITION
D. Arnott
[3] TYPE OF
Negative ion YEAR OF:
CYCLOTRON:
(I) INSTALLATION
1991
MANUFACTURER: IBA, s.a. (II) UPGRADE: 1997
MODEL: Cyclone 30
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
Typical beam employed (µA)
Yes No
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
140 90 60 10
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
137

8
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Y
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
Sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
Sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
Sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
Sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being produced)
14
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: AUSTRALIA AUL-3
[1] INSTITUTE: Peter MacCallum Cancer Institute
12 Cathedral Place
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
East Melbourne 3002, Victoria
Superconducting YEAR OF: (I)
INSTALLATION
+61 3 9656 1852
peu@petermac.unimelb.edu.au
+61 3 9656 1826
Dr. Rodney J. Hicks
Associate Professor/Director, PET Centre
Mr. Peter Eu, Radiochemist
MANUFACTURER: Oxford (II) UPGRADE:
MODEL: 12 MeV
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 12 Yes N
Maximum beam available (µA) 80
Typical beam employed (µA) 50
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
13 12 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
18 18
F-AZA, F-LT
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 18 F, Wesley Private Hospital/ 2-3
times/week
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Number
Single photon tomography (SPET)
Positron emission tomography (PET)
2
– Clinical 2
– Small animal
– Plant biochemistry
1 (Jan. 2002 delivery)
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1998
159

10
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 55 95 5 500 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 6.5 1-2/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being produced)
16
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

3. AUSTRIA
2005 COUNTRY: AUSTRIA AUS-1
[1] INSTITUTE: ARGOS Zyklotron
Betriebs-Ges.m.b.H.
LKH Klagenfurt, PET-Zentrum NMSE
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
St. Veiter Str. 47, A-9026 Klagenfurt
+43 (0) 463 500 705
+43 (0) 463 500 705 14
Dr. Dirk W. Becker
POSITION:
OTHER SENIOR STAFF:
Dipl. Ing. Mustafa Skenderi, QC
NAME/POSITION
Stefan Weber, Leading Technician
[3] TYPE OF
PT YEAR OF:
1999
CYCLOTRON:
(I) INSTALLATION
MANUFACTURER: GE Medical Systems (II) UPGRADE:
MODEL: PET Trace
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 16 8.5 Yes N
Maximum beam available (µA) 75 60
Typical beam employed (µA) 50
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
32 30 1 1 0
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) Isotope
production
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
( 18 F) FLT, 124 I, 86 Y
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
17
11

12
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 120 95-96 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
FDG 65 Yes No Yes No
DOPA 10 Yes No Yes No
MISO 30 Yes No Yes No
Fluoride 150 Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methionin Yes No Yes No
Cholin Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being produced)
18
Price/
GBq
Price/
GBq
Price/
GBq
Price
/GBq
Price/
GBq

2005 COUNTRY: AUSTRIA AUS-2
[1] INSTITUTE: Österreichisches Forschungszentrum Seibersdorf
Department of Radiopharmaka
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
A-2444 Seibersdorf
+43 0 50 550 3470
Peter.Angelberger@arcs.ac.at
+43 0 50 550 3473
Dr. Peter Angelberger
Department Head
Dr. Herbert Kvaternik, Deputy
Negative ion YEAR OF:
1999
CYCLOTRON:
(I) INSTALLATION
MANUFACTURER: GE Uppsala (II) UPGRADE:
MODEL: PET Trace
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 16.5 8.4 Yes N
Maximum beam available (µA) 75 60
Typical beam employed (µA) 40 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
15 10 4 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
Further 18 F radiopharmaceuticals
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
Number
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
19
13

18F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
14
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 130 95 250 Yes
No
20 Ne (d, α) 18 F 20
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 65 5/week Yes No Yes No
FDOPA 2 2/month Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being produced)
20
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

4. BELGIUM
2005 COUNTRY BELGIUM BEL 1
[1] INSTITUTE: ULB/Erasme hospital
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OFCYCLOTRON:
MANUFACTURER:
MODEL:
Negative ion
IBA
Cyclone-30
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
808 Lennik street, B-1070 Brussel
00.32.2.555.47.10
sgoldman@ulb.ac.be
00.32.2.555.47.01
Dr. S.Goldman
Doctor in medicine
M.Monclus (PhD, radiochemist)
M.Kadiata (PhD, radiochemist)
J.Van Naemen (cyclotron engineer)
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
3 He
4 He
1990
1999-2006
Dual Beams
Beam energies (MeV) 30 Yes No
Maximum beam available (µA) 200
Typical beam employed (µA) 30
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week
Hours/week for research Hours/week for Hours/week for
for radio. product
maintenance applications
20 3 2.5 1 0
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: 20 Radiography: 0
Materials science: 0 Proton therapy: 0
Physics: 0 Neutron therapy: 0
Activation analysis: 0 Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18
F labeled amino acid and derivatives
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] Type of imaging equipment available on-site Number of
511 KeV coincidence 0
Gamma camera 4
Single photon tomography (SPET) 4
Positron emission tomography (PET) 2
- Clinical 2
- Small animal 0
- Plant biochemistry 0
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
[17] COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)
21
15

16
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 111 95 1.5 ml 600 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 67 254/year Yes No Yes No
18
F MPPF 2 10/year Yes No Yes No
18
F F- 2 5/year Yes No Yes No
18
F
phenylalanine
2 5/year Yes No Yes No
18
F FET 2 10/year Yes No Yes No
11 C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
11
C methionine 8 154 Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N radiopharmaceuticals produced
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
13
N NH3 3 10
16 13
O(p,α) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
15
O H2O 3 10/year
16 15
O(p,pn) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu 0 Yes No Yes No
67
Ga 0 Yes No Yes No
86
Y 0 Yes No Yes No
94m
Tc 0 Yes No Yes No
103
Pd 0 Yes No Yes No
111
In 0 Yes No Yes No
123
I
0 Yes No Yes No
124
I
0 Yes No Yes No
201
Tl 0 Yes No Yes No
211
At 0 Yes No Yes No
22
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 Country: BELGIUM BEL-2
[1] Institute: Institute of Nuclear Sciences
University of Ghent
Telephone no.:
E-mail address:
Fax No.:
[2] Person in charge:
Position:
Proeftuinstraat 86, B-9000 Gent
+32 9 264 6616
karel.strijckmans@rug.ac.be
+32 9 264 6699
Professor Dr. Karel Strijckmans
Professor
Other senior staff:
Name/Position
[3] Type of cyclotron: Isochronous Year of: (i) installation 1977
Manufacturer: CGR-MeV (France) (ii) upgrade: 1982
Model: 520
[4] Cyclotron characteristics:
1 H
2 H
Dual Beams
Beam energies (MeV) 2.5 – 24 3 – 14.5 6 – 32 10 – 29 Yes No
Maximum beam available (µA) 100 100 60 60
Typical beam employed (µA) 20 5 - -
[5] Cyclotron operation:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
20-30 10 10-20

18
18 F Radionuclide production
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 15 97 0.8 50 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F radiopharmaceuticals produced
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 4 3-4/week Yes No Yes No
seronotin
receptor
antagonist
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C radiopharmaceuticals produced
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
PK 11195 4

2005 COUNTRY: BELGIUM BEL-3
[1] INSTITUTE: MDS Nordion S.A.
Zone Industrielle
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
B-6220 Fleurus
+32 10 829 211
+32 10 829 696
Dr. Claude Pirarat
Manager, Radiochemical Production
Isochronous YEAR OF:
1992
CYCLOTRON: Cyclotron H- (I) INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 30
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 15 - 30 Yes No
Maximum beam available (µA) 400
Typical beam employed (µA) 400
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
160 160 8
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
[9] Do you supply radionuclides to other institutions? If yes and available, name of
institution/s & how often?
Bulk 201 Tl – Europe, North and South America, 123 I, 201 Tl – Europe (OEM manufacturing)
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
Number
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
25
19

20
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
123
I 100 – 250 4/week Yes No Yes No
201
Tl 150 - 300 5/week Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being produced)
26
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

-
2005 COUNTRY: BELGIUM BEL-4
[1] INSTITUTE: Universite catholique de Louvain
Centre de Recherches du Cyclotron
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Compact H- YEAR OF: (I)
INSTALLATION
2, Chemin du Cyclotron, B-1348 Louvain-la-Neuve
+32 10 472 998
ryckewaert@cyc.ucl.ac.be
+32 10 452 183
Mr. Guido Ryckewaert
Director
Mr. Daniel Labar – Head of Radiochemistry
MANUFACTURER: UCL/IBA, s.a. (II) UPGRADE:
MODEL: Prototype
Cyclone 30
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 15 – 30 Yes No
Maximum beam available (µA) 350
Typical beam employed (µA) 50/300
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
30 - 4 15
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: 15 Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 2
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1987
27
21

22
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 80 95 2 200 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 40 daily Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Acetate 5 monthly Yes No Yes No
Methionine 5 weekly Yes No Yes No
Flumazenil 5 monthly Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
NH4OH 5 weekly
16 13
O(p, α) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 10 2/week
16 15
O (p, pn) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y 1 weekly Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being produced)
28
Price/G
Bq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: BELGIUM BEL-5
[1] INSTITUTE: Universite catholique de Louvain
Centre de Recherches du Cyclotron
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Isochronous
multiparticle variable
energy
2, Chemin du Cyclotron, B-1348 Louvain-la-Neuve
+32 10 472 998
ryckewaert@cyco.ucl.ac.be
+32 10 452 183
Mr. Guido Ryckewaert
Director
Mr. Daniel Labar – Head of Radiochemistry
YEAR OF: (I)
INSTALLATION
1969-1972
MANUFACTURER: Thomson – CSF. (II) UPGRADE:
MODEL: Cyclone
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 20 – 85 10 – 55 15 – 145 20 - 110 Yes No
Maximum beam available (µA) 30 20 5 20
Typical beam employed (µA) 20 10 5 10
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
production
research
maintenance
h/week for
applications
150 8 - 4 -
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? To two centres, sporadically.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Number
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
29
23

24
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
28
Mg 20 MBq Al (100%) Yes No Yes No
52
Fe 0,2 – 2 MBq Mn (100%) Yes No Yes No
94,95,96
Tc 0,1 – 0,01 MBq Mo (nat) Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being produced)
30
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: BELGIUM BEL-6
[1] INSTITUTE: Universite de Liege
Centre de Recherches du Cyclotron
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
Sart Tilman, B-4000 Liege
+32 4 366 2360
cyclotron@ulg.ac.be
+32 4 366 2946
Dr. A. Luxen
Director
C. Brihaye, Senior Radiochemist
G. Del Fiore, Senor Radiochemist
C. Lemaire, Senior Radiochemist
A. Plenevaux, Senior Radiochemist, Aerts/Pharmacist
H-/D- YEAR OF:
[3] TYPE OF
CYCLOTRON:
(I) INSTALLATION
1999
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: 18/9
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 9 Yes No
Maximum beam available (µA) 50 35
Typical beam employed (µA) 50 35
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
30 10 20 8
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) PET/30
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
Several radiopharmaceuticals specific for receptoe and gene expression imaging.
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Number
Positron emission tomography (PET) 1
–Clinical
–Small animal
–Plant biochemistry
2
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
31
25

26
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 4 Ci 95 2 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 75 250/year Yes No Yes No
FTyrosine 11 12/year Yes No Yes No
FDopa 11 12/year Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 0.37 4000/year
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being produced)
32
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: BELGIUM BEL-7
[1] INSTITUTE: University of Leuven (KUL)
Department of Nuclear Medicine, U.Z. Gasthuisberg
Herestraat 49
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
B-3000 Leuven
+32 16 34 3715
luc.mortelmans@UZ.kuleuven.ac.be
+32 16 34 3759
Luc Mortelmans, MD, PhD.
Head of Nuclear Medicine
Negative ion YEAR OF: (I) INSTALLATION 1990
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 10/5
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 10 5 Yes No
Maximum beam available (µA) 70 50
Typical beam employed (µA) 45 10
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
5 4 0 1 0
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 0
� Gamma camera 3
� Single photon tomography (SPET) 3
� Positron emission tomography (PET) 2
– Clinical 0
– Small animal 0
– Plant biochemistry 0
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
33
27

28
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 18
O (p, n) F #1 — 20 GBq 97 #1 — 0,5 mL
20 18
Ne (d, α) F
16 18
O (α, d) F
#2 — 70 GBq
#2 — 2 mL
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
18
FDG 350 GBq 1-2/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
Methionine 2 1/week Yes No Yes No
Acetate 2 0,5/week Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
13
N H3 2 3/week
15 O RADIOPHARMACEUTICALS PRODUCED
sales
sales
sales
16 O(p,x) Yes No
Yes No
Yes No
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
H2 15 O 2 2-3/week
14 N(d,n)
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being produced)
34
Yes
No
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: BELGIUM BEL-8
[1] INSTITUTE: Vrije Universiteit Brussels
Eenheid Cyclotron
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
Laarbeeklaan 103, B-1090 Brussels
+32 2 4774 864 or +32 2 477 4860
pvdwink@vucy.vub.ac.be
aherman@vucy.vub.ac.be
+32 2 477 4855
Professor A. Hermanne
Head, Cyclotron Department
Professor P. Van den Winkel
Professor J. Mertens
AVR YEAR OF:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
(I) INSTALLATION
1983
MANUFACTURER: CGR France (II) UPGRADE:
MODEL: 560
[4] CYCLOTRON CHARACTERISTICS: All beams are extracted with an electrostatic deflector – average 50%.
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 5-42 10-22 20-50 20-43 Yes No
Maximum beam available (µA) 100 100 10 20
Typical beam employed (µA) 2-30 8
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
2 3 2 10
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: 7 Proton therapy:
Physics: 3 Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No En > 25 MeV. Thin targets
neutron TOF spectroscopy
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
Neurotensin analogues; 18 F peptides and aromatic amino acids; Pd- 103 for research labelling and rodent studies;
188 186
Rh Rh
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? RUG , SCK
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site? In academic hospitals – Nuclear Medicine
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
511 KeV coincidence 1
Gamma camera > 3
Single photon tomography (SPET)
Positron emission tomography (PET)
1
–Clinical From June 2001
–Small animals
–Plant biochemistry
collaboration with RUG
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience Yes No
35
29

30
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 16 95 0.45 40 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 8 2/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/GBq
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl 37 2-4 /week Yes No Yes No Stopped in
1996
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being produced)
Additional labelled compounds:
77 Br, 56 Co, 123 I , 111 In, 206 Tl neurotensin analogues, 123 I peptides and aromatic amino acids
36

5. BRAZIL
2005 COUNTRY: BRAZIL BRA-1
[1] INSTITUTE: Instituto de Engenharia Nuclear (IEN)
Caixa Postal 68550, Cidade Universitária S/N – Ilha do Fundão
21945-970 – Rio de Janeiro – RJ
TELEPHONE NO.:
+55 21 560-4113 ext. 2184
E-MAIL ADDRESS:
suita@cnen.gov.br
[2] PERSON IN CHARGE:
Dr. Julio Cezar Suita
POSITION:
Head, Radiopharmaceutical Division
OTHER SENIOR STAFF:
Ana Maria Silveíra Braghirolli
NAME/POSITION
José Antônio Dias Furlaneto
NAME/POSITION
Jackson Louis Queiroz de Britto
Migual Ângelo Valle Bastos
[3] TYPE OF
Isochronous YEAR OF:
1975
CYCLOTRON:
(I) INSTALLATION
MANUFACTURER: The Cyclotron
Corporation
(II) UPGRADE:
MODEL: CV-28
[4] CYCLOTRON CHARACTERISTICS: Variable energy and multiparticle
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 24 14 36 28 Yes No
Maximum beam available (µA) 50 75 30 25
Typical beam employed (µA) 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
32 20 4 8
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No Occasionally
Mössbauer sources? (specify which & quantity) Yes No Occasionally
X ray sources? (specify which & quantity) Yes No Occasionally
Intense neutron beam? (specify average En = ?) 17 MeV Yes No Occasionally
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
n-isopropyl para-iodine anphetamine labelled with 123 I
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
Number
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
37
31

32
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (ml)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 11 96 0.3 30 Yes
No
20 Ne (d, α) 18 F
16 O (α, d) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
Frequency of
production
Used on site Distribution/
sales
18 FDG 6 2/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Frequency of
production
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
15 3/week Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being produced)
Meta – iodinebenzilguanine labelled with 123 I has also been produced.
38
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: BRAZIL BRA-2
[1] INSTITUTE: Instituto de Pesquisas Energéticas e Nucleares – IPEN/CNEN-
SP
Travesa , R, 400, Cidade Universitária
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
CEP – 05508-900, São Paulo, SP
+55 11 3816 9275/ 9265
wdelima@net.ipen.br
+55 11 3816 9263
Dr. Wanderley de Lima
Head, Cyclotron Laboratory
Dra. C. Pagano G. da Silva, Head – Radioisotope Department
Uylton Matsoda
[3] TYPE OF
Fixed field, fixed
Valdir Sciani
YEAR OF: (I)
1998
CYCLOTRON: frequency
INSTALLATION
MANUFACTURER: TBA, S.A. (II) UPGRADE:
MODEL: Cyclone - 30
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 15-30 Yes No
Maximum beam available (µA) 500
Typical beam employed (µA) 200
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20 18 - 2 -
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
201 111
Tl, In
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Hospitals and medical centers/
weekly
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
Number
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
39
33

34
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year
18 OH2 (ml)
18 O2 (ml)
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 37 94 2 200 Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
FDG 500 2/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
18 OH2
?
Price/G
Bq
Price/G
Bq
Nuclear reaction used Distribution/sales Price/G
Bq
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/G
Bq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/G
(list)
(GBq)
production
sales
Bq
64
Cu Yes No Yes No
67
Ga 50 1/week Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
20 1/week Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being produced)
As of June 2001, MIBG 123 I, HEPPURAN 123 I and radiopharmaceutical for neuroreceptors are produced.
40

6. CANADA
2005 COUNTRY: CANADA CAN-1
[1] INSTITUTE: Clark Institute of Psychiatry
250 College Street
Toronto, ON M5T 1R8
TELEPHONE NO.:
E-MAIL ADDRESS:
+1 416 979 4651
FAX NO.:
+1 416 979 4656
[2] PERSON IN CHARGE:
Dr. Sylvain Houle
POSITION:
Head, PET Centre
OTHER SENIOR STAFF:
Allan A. Wilson
NAME/POSITION
Jean Da Silva
[3] TYPE OF
Fixed energy YEAR OF: (I)
1991
CYCLOTRON: isochronous
INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL: MC-17
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 17 8.5 Yes No
Maximum beam available (µA) 15-60 20-25
Typical beam employed (µA) 10-40 10-12
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20-25 20-22 2-3 (additional 1weekmaintenance/y)
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Number
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
41
35

36
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year
18 OH2 (ml)
18 O2 (ml)
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
F-FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
11
C-raclopride Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
15 O-water
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
18 OH2
?
Price/G
Bq
Price/G
Bq
Price/G
Bq
Price/G
Bq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/G
(list)
(GBq)
production
sales
Bq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being produced)
42

2005 COUNTRY CANADA CAN -2
[1] INSTITUTE: Edmonton PET Centre, Cross Cancer Institute
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
MODEL:
Negative ion
Advanced Cyclotron
Systems
TR19/9
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Edmonton, AB, T6G 1Z2, Canada
780-989-4311
stevemcq@cancerboard.ab.ca
780-432-8483
Steve McQuarrie, PhD
Director, Cyclotron Operations and
Professor, Faculty of Medicine, University of Alberta
John Wilson, PhD
Sr. Cyclotron Operator
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 19 9 Yes x No
Maximum beam available (µA) 200 100 200
Typical beam employed (µA) 75 20 75
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week for
Hours/week for research Hours/week for Hours/week for
radioproduction
maintenance applications
30 30 1
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (Medical research) 30
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No X
Mössbauer sources? (specify which & quantity) Yes No X
X ray sources? (specify which & quantity) Yes No X
Intense neutron beam? (specify average En = ?) Yes No X
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
Radionuclides: 124 I, 64 Cu, 86 Y
Radiopharmaceuticals: Development of new tracers to study metabolic processes in cancer.
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Foothills Hospital, Calgary. 3 – 4/week
Health Sciences Centre, Winnipeg. 3 -4/week
Yes X No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes X No
[11] Type of imaging equipment available on-site
511 KeV coincidence
Gamma camera
Number of
Single photon tomography (SPET)
Positron emission tomography (PET)
3
–Clinical 3
–Small animal
–Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No X
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No X
[14] Is the cyclotron used for targetry development? Yes X No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes X No
[16] Does your institute accept IAEA research fellows for training/experience? Yes X No
3 He
4 He
2001
N/A
43
37

38
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 180 95 2 Yes X
No
Ne (d, α) 18 F 0
16 O (α, x) 18 F 0
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 50 - 100 3/day Yes X No Yes X No
18
FES 2 - 10 1/week Yes X No Yes No X
18
FLT 2 - 10 1/week Yes X No Yes No X
18
FAZA 2 - 10 3/week Yes X No Yes No X
11 C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
11
C-choline Yes X No Yes No X
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
18 OH2
?
Price/G
Bq
Price/G
Bq
Price/G
Bq
Price/G
Bq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
< 0.05 1 – 4 /month Yes X No Yes No X
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)
The Edmonton PET centre is a basic science and translational research centre whose mission is the discovery,
elucidation and clinical evaluation of the molecular mechanisms associated with cancer.
44

2005 COUNTRY: CANADA CAN-3
[1] INSTITUTE: Hamilton Health Sciences Corporation
Department of Nuclear Medicine
Mc Master Site, 1200 Main Street West, Room 1 P 6
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
Hamilton, ON L8N3Z5
+1 905 521 2100 ext. 76893/73025
chiraklr@mcmaster.ca
+1 905 546 1125
Dr. Raman Chirakal
Radiochemist
Jia Juen Chen
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
RDS 112 YEAR OF: (I)
1990
CYCLOTRON:
INSTALLATION
MANUFACTURER:
MODEL:
CTI, Inc. (II) UPGRADE:
[4] CYCLOTRON CHARACTERISTICS: Negative ion cyclotron
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 10 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
5 3 2 1 3
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 3 Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) Research - 2
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Ottawa Heart Institute, 1/week
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
45
39

40
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year
18 OH2 (ml)
18 O2 (ml)
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 18.5 94 0.8 14 200 10 Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
FDG 10 6/week Yes No Yes No
J6 – F MT 1.12 1/week Yes No Yes No
J6 - FDOPA 0.3 2/month Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
ACETATE 0.3 2/month Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
AMMONIA 0.8 4/week
16 13
O(p, α) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
WATER 5.6 9/month
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
46
18 OH2
?
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: CANADA CAN-4
[1] INSTITUTE: Montreal Neurological Institute
McGill University
3801, University Street
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Montreal, Quebec H3A2BA
+1 514 398 8526
mirko@pet.mni.mcgill.ca
+1 514 398 8540
Prof. Mirko Diksic
Dean Jolly
Negative ion YEAR OF: (I)
INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 18/9
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 9 Yes No
Maximum beam available (µA) 100 60
Typical beam employed (µA) 30-40 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20-30 20-30 2-3
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Number
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
2
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
1993
47
41

42
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
F-FDG Yes No Yes No
18
F-DOPA Yes No Yes No
11 C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
11
C-RO Yes No Yes No
Deprenyl Yes No Yes No
α-methyl-
L-trypotophan
Yes No Yes No
Bensotropine Yes No Yes No
PK-11195 Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being produced)
48

2005 COUNTRY: CANADA CAN-5
[1] INSTITUTE: TRIUMF
4004 Westbrook Mall
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Vancouver, BC V6T 2A3
+1 604 222 1047
Zeisler@triumf.ca
+1 604 222 1074
Dr. Stefan K. Zeisler
Manager, Applied Technology Groups
Mr. R. Van Den Elzen
H- / sector-focused YEAR OF: (I)
INSTALLATION
1990
MANUFACTURER: EBCO (II) UPGRADE: 1995
MODEL: TR30
[4] CYCLOTRON CHARACTERISTICS
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 30 Yes No
Maximum beam available (µA) 1200
Typical beam employed (µA) 1000
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
168 148 - 20 -
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
49
43

44
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd ~7/week Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
3/week Yes No Yes No
201
Tl ~5/week Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being produced)
Yields and prices of commercial products are confidential and cannot be reported.
50
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: CANADA CAN-6
[1] INSTITUTE: TRIUMF
4004 Wesbrook Mall
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER: EBCO
MODEL: TR30-2
[4] CYCLOTRON CHARACTERISTICS
1 H
Vancouver, BC V6T 2A3
+1 604 222-7364
Zeisler@triumf.ca
+1 604 221-0436
Dr. Stefan K. Zeisler
Manager, Applied Technology Group
Mr. R. van den Elzen
H- / sector-focused YEAR OF: (I)
INSTALLATION
2 H
Dual Beams
Beam energies (MeV) 30 Yes No
Maximum beam available (µA) 1200
Typical beam employed (µA) 1000
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
168 148 - 20 -
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
[9] Do you supply radionuclides to other institutions?
Yes No
If yes and available, name of institution/s & how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
3 He
4 He
2002
Yes No
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
51
45

46
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd ~7/week Yes No Yes No
111
In Yes No Yes No
123
I
3/week Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may include names of additional labelled compounds/radiopharmaceuticals being produced)
Yields and prices of commercial products are confidential and cannot be reported.
52
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: CANADA CAN-7
[1] INSTITUTE: TRIUMF
4004 Wesbrook Mall
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Vancouver, BC V6T 2A3
+1 604 222-7364
zeisler@triumf.ca
+1 604 221-0436
Dr. Stefan K. Zeisler
Manager, Applied Technology Group
Mr. R. van den Elzen
520 MeV H-/ YEAR OF: (I)
1962
CYCLOTRON: sector-focused INSTALLATION
MANUFACTURER:
MODEL:
TRIUMF (II) UPGRADE: 1997
[4] CYCLOTRON CHARACTERISTICS: Isotope production beam line only
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 500 Yes No
Maximum beam available (µA) 100
Typical beam employed (µA) 70
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
production
research
maintenance
144 4 months/year
h/week for
applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
Number
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
53
47

48
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
82 Sr/ 82 Rb, Mo(p, spall) — ~ 8 targets/year
54
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: CANADA CAN-8
[1] INSTITUTE: TRIUMF
4004 Wesbrook Mall
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Vancouver, BC V6T 2A3
+1 604 222-7364
zeisler@triumf.ca
+1 604 221-0436
Dr. Stefan K. Zeisler
Manager, Applied Technology Group
Mr. R. van den Elzen
H-/sector-focused YEAR OF:
INSTALLATION
(I)
1980
(II) UPGRADE: 1991
MANUFACTURER: The Cyclotron
Corporation
MODEL: CP42
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 42 Yes No
Maximum beam available (µA) 200
Typical beam employed (µA) 180
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
168 158 1 9 -
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? University of British Columbia,
Botany Department, 1-2 times/week
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
Yes No
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
55
49

50
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of
(list)
batch (GBq) production
13 N – NO3 7 1/week
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Nuclear reaction used Distribution/
sales
16
O(p, α) Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga 5/week Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In 1/month Yes No Yes No
123
I
3/week Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Yields and prices of commercial products are confidential and cannot be reported.
56
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: CANADA CAN-9
[1] INSTITUTE: UBC/TRIUMF PET Programme
4004 Wesbrook Mall
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Vancouver, BC V6T 2A3
+1 604 222 1047
truth@triumf.ca
+1 604 222 1074
Dr. Thomas Ruth
PET Director/Senior Research Scientist
Ken Buckley, PET Project Engineer
Negative ion, YEAR OF: (I)
1994
CYCLOTRON: sector focused
INSTALLATION
MANUFACTURER: EBCO (II) UPGRADE:
MODEL: TR13
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 13 Yes No
Maximum beam available (µA) 100
Typical beam employed (µA) 50
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
25 15 10 4 2
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: 2 Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
Same as below.
[9] Do you supply radionuclides to other institutions?
Yes No
If yes and available, name of institution/s & how often? Various, on request
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET) 3
–Clinical
–Small animal
–Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
57
51

52
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 18
O (p, n) F F 2 – 18.5 >90 0.5 500 50 1 Ye
20 18
Ne (d, α) F
16 18
O (α, d) F
F -26
No
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
18
FDG 3.7 1/week Yes No Yes No
18
F SETOPERONE 1.8 1/week Yes No Yes No
18 F DOPA 0.8 2/week Yes No Yes No
18 F EF5 0.8

7. CHINA
2005 COUNTRY: CHINA CPR-1
[1] INSTITUTE: China Institute of Atomic Energy
P.O. Box 275 (99)
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
Beijing 102413
+86 01 69358090
+86 01 69357195
Dr. Li Da Kang
OTHER SENIOR STAFF:
Zhao Gui Zhi; Zhao Zhen Lu
NAME/POSITION
Shen de Heng Xu Shu He
[3] TYPE OF
Negative ion YEAR OF: (I)
1995
CYCLOTRON:
INSTALLATION
MANUFACTURER: IBA sa (II) UPGRADE:
MODEL: Cyclone 30
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
15-30 Yes No
Typical beam employed (µA) 100-220
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
production
research
maintenance
4 days/week 4 days/week 1 day/week
h/week for
applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
123 186
I, Re
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 57 Co to USA 1 per month
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET) 2
–Clinical
–Small animal
–Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
59
53

54
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
60
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: CHINA CPR-2
[1] INSTITUTE: Guangdong Province People's Hospital
96 Dong Chuan Road
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Guangzhou 5 10 100
+11 86 20 8382 7812
+11 86 20 8382 5453
Dr. Tang Au-Wu
YEAR OF: (I)
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 111
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 11.1 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 38.5
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
18 12 2 2 2
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET) 2
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
3 He
4 He
1999
Yes No
Yes No
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
61
55

56
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 1.2 260 Yes
No
Ne (d,α) 18 F
16 O (α , d) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
FDG 30 4/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
Frequency of
production
AMMONIA 4 1/week
15 O RADIOPHARMACEUTICALS PRODUCED
Nuclear reaction used Distribution/
sales
16 O (p , α ) 13 N Yes No
Yes No
Yes No
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 22 3/month
15 15
N (p , n ) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
62
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: CHINA CPR-3
[1] INSTITUTE: Hong Kong Sanatorium & Hospital, Ltd.
Department of Radiology & Radiotherapy
2 Village Road, Happy Valley
Hong Kong
TELEPHONE NO.:
E-MAIL ADDRESS:
+11 852 2835 8989
FAX NO.:
+11 852 2835 8825
[2] PERSON IN CHARGE:
Dr. C.L. Ho
POSITION:
Director, Department of Nuclear Medicine and PET
OTHER SENIOR STAFF:
Dr. David W.C. Young, Deputy Director
NAME/POSITION
Mr. Steve H.Q. Sitt, Manager
Dr. M.K. Cheung, Radiochemist
[3] TYPE OF
- YEAR OF: (I)
1998
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE: -
MODEL: RDS 111
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
6 5 – 18 F; 1 – 11 C 1 6
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
15 18 18 18 18
O-oxygen; F-Fluoroestradiol, F-choline, F-fluoro-α-methyltyrosine, F-DOPA
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 1
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
63
57

58
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F ~ 37 95 1100 Y
No
Ne(d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG ~ 15 5 batches/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Acetate ~ 3.7 1-2/week Yes No Yes No
Choline ~ 3.7 1/month Yes No Yes No
Methionine ~ 3.7 1/ month Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia ~ 1.8 1/month O(p, α) 13 N Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
64
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: CHINA CPR-4
[1] INSTITUTE: Key Laboratory of Radiopharmaceuticals (Beijing Normal
University), Ministry of Education of China
Beijing Normal University
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Beijing ,100875 , P. R. China
+86-01-6220 7786
zhulin@bnu.edu.cn
+86-01-62207786
Professor Lin Zhu
Zhi-Gang Tang/senior Engineer
Zheng-Hao Liu/Professor
Ming-Da Hua/Professor
Positive ion YEAR OF:
(I) INSTALLATION
MANUFACTURER: TCC (II) UPGRADE:
MODEL: CS-22
[4] CYCLOTRON CHARACTERISTICS: Our CS-22 will be used to produce radiopharmaceuticals in 2002.
1 H
2 H
Dual Beams
Beam energies (MeV) 22 11 29 Yes No
Maximum beam available (µA) 50 50 50
Typical beam employed (µA)
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
production
h/week for
research
3 He
h/week for
maintenance
4 He
1997
h/week for
applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 67 111 18 18
F, Ga, In, FDG, F - DOPA
[9] Do you supply radionuclides to other institutions?
Yes No
If yes and available, name of institution/s & how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
microSPECT 1 Next year
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
65
59

60
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 95 0.3 Yes
No
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
18
F - DOPA Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
66
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: CHINA CPR-5
[1] INSTITUTE: Institute of Applied Chemistry
Beijing Normal University
Bejing Cyclotron Produced Radiopharmaceutical Laboratory
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
100875 Beijing, China P.R.
+86 01 6220 7786 or 8396
Liuboli@bnu.edu.cn
+86 01 6220 0567
Professor Bo Li Liu
Dean of Radiochemistry
Huang Zheng Xing
Professor Liu Zheng Hao
Zhang Hui Xing
Chen Ru Yi
Positive ion YEAR OF:
[3] TYPE OF
CYCLOTRON:
(I) INSTALLATION
1986
MANUFACTURER: TCC (II) UPGRADE:
MODEL: CS-30
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 26 15 30 Yes No
Maximum beam available (µA) 200 200 100
Typical beam employed (µA) 110
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
Number
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
67
61

62
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year
18 OH2 (ml)
18 O2 (ml)
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F Ye
No
Ne (d, α) 18 F
16 O (α , d) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
68
18 OH2
?
Price/G
Bq
Price/G
Bq
Price/G
Bq
Price/G
Bq
Price/G
Bq

COUNTRY: CHINA CPR-6
[1] INSTITUTE: Peking Union Medical College Hospital
Nuclear Medicine Department PET Centre
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Beijing 100730
+86 10 652 33129
+86 10 652 33129
Dr. Chien Chou
YEAR OF: (I)
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 111
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 35-40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
4 – 8 2 - 3 1 - 2 1 - 2
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence EXACT HR +
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
3 He
4 He
1998
Yes No
Yes No
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
69
63

64
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year
18 OH2 (ml)
18 O2 (ml)
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 14.8 - 29.6 > 94 1.1 Ye
No
Ne (d, α) 18 F
16 O (α , d) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 7.4 – 11.1 2-3/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
18 F-F–Ethyl–tyrosine: not in clinical trial yet.
70
18 OH2
?
Price/G
Bq
Price/G
Bq
Price/G
Bq
Price/G
Bq
Price/G
Bq

2005 COUNTRY: CHINA CPR-7
[1] INSTITUTE: Shanghai Institute of Nuclear Research
P.O. Box 800-204
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
201800 Shanghai
+86 21 5955 3634
wyxydz@ihw.com.cn
+86 21 5955 2509
Professor Wang Yongxian
Director
Cao Benhong
Gao Wenzhao
Yuyi
Negative ion YEAR OF: (I)
INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 30
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) Yes No
Maximum beam available (µA) 400
Typical beam employed (µA) 150
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
production
h/week for
research
3 He
h/week for
maintenance
4 He
1996
h/week for
applications
50 50
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
Yes No
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
71
65

66
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year
18 OH2 (ml)
18 O2 (ml)
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F Ye
No
Ne (d, α) 18 F
16 O (α ,d) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 5500 - 7400 2/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga 12950 - 14800 1/week Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl 14800- 16650 2/week Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
72
18 OH2
?
Price/G
Bq
Price/G
Bq
Price/G
Bq
Price/G
Bq
Price/G
Bq

2005 COUNTRY: CHINA CPR-8
[1] INSTITUTE: The PLA General Hospital
28 Fuxing Road
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Beijing 100853
+86 10 6693 9424
tianih@public.east.cn.net or zhangim@sina.com
+86 10 681 31142
Professor Jia-he Tian
Jinming Zhang
YEAR OF: (I)
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 111
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA)
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
production
research
maintenance
8 4 1 2
3 He
4 He
1999
h/week for
applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET) 1
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
Yes No
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
73
67

68
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year
18 OH2 (ml)
18 O2 (ml)
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 37 1.1 150 Ye
No
Ne (d,α) 18 F
16 O (α ,d) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
FDG 18.5 2-4/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq) production
sales
Acetate 3.7 1-2/week Yes No Yes No
Methioine 2 0-1/week Yes No Yes No
RACLOPRIDE 2 0-1/week Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
AMMONIA 1.5 2/week
16 13
O(p, α ) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
WATER 74 0-1/week
15 15
N(p, n ) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
74
18 OH2
?
Price/G
Bq
Price/G
Bq
Price/G
Bq
Price/G
Bq
Price/G
Bq

2005 COUNTRY: CHINA CPR-9
[1] INSTITUTE: Zibo Wanjie Hospital
Boshan, Zibo
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
Shandong
+86 533 4650 000 8730
+86 533 4650 830
Dr. Sun Qiyin
Wang Ming Fang
Zhao Jun
Wang Changqing
Li Jiamin
[3] TYPE OF
Negative ion YEAR OF: (I)
1995
CYCLOTRON:
INSTALLATION
MANUFACTURER: GE (II) UPGRADE:
MODEL: PET Trace
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
16.5 Yes No
Typical beam employed (µA) 20-30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
6 5 7
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11 15 82
C, O, Rb
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
75
69

70
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year
18 OH2 (ml)
18 O2 (ml)
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F Ye
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
76
18 OH2
?
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

8. CZECH REPUBLIC
2005 COUNTRY: CZECH REPUBLIC CZR-1
[1] INSTITUTE: Nuclear Physics Institute
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Rez near Prague, 25068 Rez
+420 2 6617 3613
stursa@ujf.cas.cz
+420 2 20941130
Ing. Jan Stursa, MSc.
Head of the Cyclotron Division
J. Kucera, Deputy Head
J. Lacman, Control System
M. Cihak, Beam Dynamics
Isochronous YEAR OF: (I)
INSTALLATION
1977 First beam
MANUFACTURER: JINR Dubna, Russia (II) UPGRADE: 1992 Axial injection
MODEL: U-120M 1997 H - , D - Beams
2000 New beam line
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 10-38 10-20 17-53 20-40 Yes No
Maximum beam available (µA) 40 25 3 3
Typical beam employed (µA) 20 10 3 3
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
78 62 13 1 2
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) - Stent
activation
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) = 15 MeV Yes No 7
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
86 123
Y, I
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
- Clinical
- Small animal
- Plant biochemistry
Number
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
77
71

72
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year
18 OH2 (ml)
18 O2 (ml)
18 OH2 (g)
18 O2 (l)
18 18
O (p, n) F
20 18
Ne (d, α) F
16 18
O (α, d) F
80 95 2.0 1000 Ye
No
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
18
FDG 45 12/week Yes No Yes No 335
USD
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga 4 1/week Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
clinical studies Yes No Yes No
124
I
Yes No Yes No
201
Tl 4 1/week Yes No Yes No
211
At 1 1/month Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
81 Rb/ 81m Kr – radionuclide generator, 3/week, not used on site, distribution – yes.
78
18 OH2
?
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: CZECH REPUBLIC CZR-2
[1] INSTITUTE: Nuclear Research Institute Rez plc
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
250 68 Rez
+42 02 572 16 982 or +42 02 570 90 616
mailto:koy@ujv.cz or ami@ ujv.cz
+4202 572 15 949
Ing. Michal Antos
Head, Department of PET Radiopharmaceuticals
Ing. Karel Mudra, Cyclone Operator
Ing. Petr Kopecky, Vice Director – Division of
Radiopharmaceuticals
IBA cyclone YEAR OF: (I)
INSTALLATION
MANUFACTURER: IBA Belgium (II) UPGRADE:
MODEL: Cyclone 18/9
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 18 9 Yes No
Maximum beam available (µA) 80 40 Possible, but
not used
Typical beam employed (µA) Up to 37 not used
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research maintenance applications
36 36 0 6 0
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
3 He
4 He
1999
18 F -5 GBq/year
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
18 11
F- FDG, C- labelled pharmaceuticals
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yellow Hill Hospital Brno,FDG twice per day
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
511 KeV coincidence
Gamma camera
0
Single photon tomography (SPET) 2
Positron emission tomography (PET) 2 1xPET,
1xPET/CT
- Clinical
- Small animal
- Plant biochemistry
x
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
Yes No
agricultural applications such as plant biochemistry/research?
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
79
73

74
18 F RADIONUCLIDE PRODUCTION
Production Typical
production yield
(GBq)
18 O (p, n) 18 F 140/2hrs-large
65/1,5hrs-medium
20 Ne (d, α) 18 F Not used
16 O (α, d) 18 F Not used
18 F RADIOPHARMACEUTICALS PRODUCED
% Isotopic
enrichment
18 O used
>95 2,0 (2x)-large
1,0 (1x)medium
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
32g/week
totally
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 50 –large volume 2x/ day Yes No Yes No
18 FDG 20-medium
volume
1x/ day Yes No Yes No
Yes No Yes No
Yes No Yes No
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Routine production of FDG only – Monday to Thursday 3 batches per day, Friday to Sunday 2 batches per day.
80
Ye
No
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

9. DENMARK
2005 COUNTRY: DENMARK DEN-1
[1] INSTITUTE: University Hospital of Copenhagen
Cyclotron and PET Unit, KF 3982
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
Blegdamsvej 9, DK – 2100 Copenhagen
+45 3545 3915
mikaelj@rh.dk
+45 3545 3898
Dr. Mikael Jensen
Physicist-in-Chief
Holger Jensen, Physicist
Nic Gillings, Chemist
Jacob Madsen, Chemist
Negative ion, YEAR OF: (I)
1992
CYCLOTRON: sector-focused INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE: 1994 – Addition of positive
ions and 4 He
MODEL: MC 32-NI
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 32 16 - 32 Yes No
Maximum beam available (µA) 100 80 30
Typical beam employed (µA) 20 10 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
30-40 25 5 2 0-8
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: 1 Neutron therapy:
Activation analysis: Other (specify) Space component tests
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11
C – FLB 457
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 6
� Single photon tomography (SPET) 1
� Positron emission tomography (PET)
– Clinical 2
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
81
75

76
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 18
O (p, n) F
20 18
Ne (d, α) F
16 18
O (α, d) F
40 >95 1.2 200 Ye
No
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/GBq
(list)
(GBq) production
sales
if available
18
FDG 25 2-3/week Yes No Yes No ~600 Euro
18
F -ALTANSERIN 4 1/week Yes No Yes No ~400 USD
per. patient
dose
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of
(list)
batch (GBq) production
Ammonia 2 2-8/week
15 O RADIOPHARMACEUTICALS PRODUCED
Nuclear reaction used Distribution/
sales
16 13
O (p, α) N Yes No
Yes No
Yes No
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water on line 8 hours/week
14 15
N (d, n ) O
CO on line
14 15
N (d, n ) O
OO on line
14 15
N (d, n ) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
0.1 5/year Yes No Yes No
201
Tl Yes No Yes No
211
At 1 1/week Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
The home of : gas phase Methyl iodine - 11 C, 10 C - carbon dioxide
Production of 81 Rb/ 81m Kr generators 16/week – 12 GBq/week.
82
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY DENMARK DEN-2
[1] INSTITUTE: The Hevesy Laboratory
Risø National Lab
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
MODEL:
Compact, negative
ion
General Electric
Pettrace
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
P.O.Box 49, DK 4000 Roskilde, Denmark
+45 4677 5300
isotop@risoe.dk
+45 4677 5347
Mikael Jensen
Professor
Head of Programme Lars Martiny
Radiochemist Palle Rasmussen
Physicist Dennis Ringkjøbing
Radiochemist Sorin Aburel
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 16,5 8 Yes X No
Maximum beam available (µA) 100 60
Typical beam employed (µA) 60 50
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week
for radionuclide
production
3 He
4 He
Hours/week for research Hours/week for
maintenance
2004
Hours/week for
applications
40 36 4
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] Type of imaging equipment available on-site
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
Number of
–Clinical 3
–Small animal
–Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes x No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No X
[14] Is the cyclotron used for targetry development? Yes X No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes X No
[16] Does your institute accept IAEA research fellows for training/experience? Yes X No
83
77

78
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 150 95-97 2,1 Yes X
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 100 2/week Yes No X Yes X No
18
FDOPA 0.4 1/month Yes No Yes No
18
Fluoride 0.5 1/month Yes No Yes No
18
FMISO 2 1/month Yes No Yes No
11 C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Raclopride 0.5 1/week Yes No Yes No
PK11195 0.5 1/month Yes No Yes No
Acetate 5 1/month Yes No Yes No
Methonine 3 1/month Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 4 2/week
16
O(p,α) Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 3 daily
14
N(d,n)
Oxygen 6 1/week
14
N(d,n)
CO 3 1/week
14
N(d,n)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu 3 1/mo Yes x No Yes x No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)
84

10. EGYPT
2005 COUNTRY EGYPT EGY-1
[1] INSTITUTE: Cyclotron Project, Nuclear Research Center
Atomic Energy Authority, 13759,
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
MODEL:
AVF
NIIEFA
MGC-20
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Egypt
+(202)4620786
+(202)4620786
Ppof.Dr. Sh.M. Saad
Supervisor
Prof.Dr. M.N.H. Comsan
Prof.Dr. Z.A. Saleh
Dr. S. Abdel-Samad
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 5-18 3-10 8-24 6-20 Yes No X
Maximum beam available (µA) 50 50 25 25
Typical beam employed (µA) 30 -- 10 10
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week for
Hours/week for research Hours/week for Hours/week for
radioproduction
maintenance applications
40 Not yet 30 10 --
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
I-123, Ga-67, In-111, Cu-64
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No X
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No X
[11] Type of imaging equipment available on-site
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
Number of
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes X No
[14] Is the cyclotron used for targetry development? Yes X No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes X No
[16] Does your institute accept IAEA research fellows for training/experience? Yes X No
3 He
4 He
2000
85
79

80
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F In plan In plan In plan Ye
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Trial Yes No Yes No
67
Ga Trial Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Trial Yes No Yes No
123
I
Trial Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)
86

11. FINLAND
2005 COUNTRY: FINLAND FIN-1
[1] INSTITUTE: Laboratory of Radiochemistry
University of Helsinki, Department of Chemistry
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
P.O. Box 55, 00014 University of Helsinki
+358 9191 50133
kerttuli.helariutta@helsinki.fi
+358 9191 50121
Dr. Kerttuli Helariutta ,
Senior Laboratory Manager
Martti Hakanen, Laboratory Manager
YEAR OF: (I)
INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 10/5
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 10 5 Yes No
Maximum beam available (µA) 80 40
Typical beam employed (µA) 10-20 Not yet used
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
~ 4.5 ~ 4 ~ 0.5 ~ 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: A couple of times Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
57
Co
X ray sources? (specify which & quantity) Yes No
109
Ag
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
124 64 86
I, Cu , Y
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Hospitals (Helsinli, Tampere,
Lahti, Kuojno) 1-3 times/week
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
- Clinical
- Small animal
- Plant biochemistry
Number
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1997
87
81

82
8 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 1-5 0.4, 2.0 Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 1-3/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
We are still in the beginning of using Cyclotron. Probably this year, the production of radionuclides will increase
significantly.
88

2005 COUNTRY: FINLAND FIN-2
[1] INSTITUTE: Turku PET Centre
Turku University Central Hospital
Kiinamyllynkatu 4-8
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
FIN-20520 Turku
+358 2 313 1860
hannu.sipila@tyks.fi
+358 2 313 2882
Mr. Hannu Sipilä
Chemist
Mika Teräs, Hospital Physicist
Kari Lindberg, Technician
Jukka Kaikkonen, Technician
Positive ion 2H YEAR OF: (I)
INSTALLATION
MANUFACTURER: IBA, s.a. Belgium (II) UPGRADE:
MODEL: Cyclone 3
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 3-7 Yes No
Maximum beam available (µA) 60
Typical beam employed (µA) 5-35
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
production
h/week for
research
3 He
h/week for
maintenance
4 He
1992
h/week for
applications
14 14
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography: 14
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET) 4
� Positron emission tomography (PET) 4
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
89
83

84
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
H2 O 0.2 – 1.4 4 days/week
14 15
N (d, n) O
CO 2.6 0-1 days/week
O2 1.2 0-1 day/week
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
90
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: FINLAND FIN-3
[1] INSTITUTE: Turku PET Centre
Accelerator Laboratory
Äbo Akademi, Porthansgatan 3
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
FIN-20500 Turku
+358 2 2654 608
esheselius@abo.fi
+358 2 2654 912
Dr. Sven-Johan Heselius
Director
Olof Solin; Jörgen Bergman; Jan-Olof Lill;
Ulf Hällsten; Stefen Johansson; Erkki Stenvall;
Per Olof Eriksson
AVF YEAR OF:
INSTALLATION
(I)
(II) UPGRADE:
MANUFACTURER: D.V. Efremov
Institute
MODEL: MGC-20
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 3-20 6-10.5 9-28 12-21 Yes No
Maximum beam available (µA) 30 30 20 20
Typical beam employed (µA) 300 300 80 80
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
42 32 8
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? …….
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 2
� Gamma camera 4
� Single photon tomography (SPET) 4
� Positron emission tomography (PET) 2
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
1974
91
85

86
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced
92
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: FINLAND FIN-4
[1] INSTITUTE: University of Jyväskylä
Department of Physics, P.O. Box 35
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
40351 Jyväskylä
+358 14 260 2350
esko.liukkonen@phys.jyu.fi
+358 14 260 2351
Professor Esko Liukkonen
Professor
Pauli Heikkinen, in charge of Accelerator Physics
Hannu Koivisto, in charge of Ion Sources
Teuvo Poikolainen, Radiation Safety Officer
Isochronous YEAR OF: (I)
1990-92
CYCLOTRON:
INSTALLATION
MANUFACTURER: JYFL, Scandinotrix (II) UPGRADE: 2000 for H - MODEL:
acceleration
[4] CYCLOTRON CHARACTERISTICS: E = q2 m 130 MeV
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 5-70 5-65 15 - 168 Yes No
Maximum beam available (µA) 100 50 20
Typical beam employed (µA) 30-50 0.1 - 10 0.1 - 10
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
10 120 18 20
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: 20 Proton therapy:
Physics: 120 Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? …….
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
93
87

88
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
150 1/week Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced
94
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

12. FRANCE
2005 COUNTRY: FRANCE FRA-1
[1] INSTITUTE: Centre Antoine Lacassagne
Laboratoire du Cyclotron
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
[3]
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
TYPE OF
Compact isochronous
CYCLOTRON: - negative ion
MANUFACTURER: Centre Antoine
Lacassagne
MODEL:
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
227, Avenue de la Lanterne, 06200 Nice
+33 4 920 31070
Pierre.Mandrillon@FNCLCC.fr
+33 4 920 31095
Dr. Pierre Mandrillon
Head of Cyclotron Laboratory
Donadey
Trimud
Giusto
YEAR OF: (I)
INSTALLATION
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 65 65 65 65 Yes No
Maximum beam available (µA) 40 40 40 40
Typical beam employed (µA) 0.1 - 25 0.1 - 25 0.1 - 25 0.1 - 25
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
30 10 20
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy: 20
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11
C
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1991
95
89

90
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 150 Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
96
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY FRANCE FRA-2
[1] INSTITUTE: CNRS/CERI
3a rue de la Férollerie
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
MODEL:
K50 isochronous
CGR MeV
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
45071 Orléans cedex 2 France
+33238255410
blondiaux@cnrs-orleans.fr
+33238630271
Gilbert Blondiaux
Director
J.Briaud : Technical director
L.Le Polotec : assistant of the technical director
M.F.Barthe : leader of the research staff
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
3 He
4 He
1974
upgraded continuous by the
technical staff from 1998-
2005
Dual Beams
Beam energies (MeV) 36 25 65 50 Yes No X
Maximum beam available (µA) 50 40 10 5
Typical beam employed (µA) 50 40 5 5
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week
for radionuclide
production
Hours/week for research Hours/week for
maintenance
Hours/week for
applications
64 6 30 8 20
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: 30 Proton therapy:
Physics: Neutron therapy: 20
Activation analysis: 5 Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes X No 25
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 11 81m 64 123
F for FDG and fluoride, C, Kr, Cu, I,
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No X
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No X
out on-site?
[11] Type of imaging equipment available on-site Number of
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical
–Small animal 1 in end 2006
–Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No X
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? X No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes X No
97
91

92
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F Ye
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At 0.1 3/month Yes No X Yes No X
[17] COMMENTS:(e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)
We are installing on the site a production of classical 511 keV positrons emitter form PET imaging of small animals.
We are also starting this month a production of 211 At for research A large part of the beam time of this machine is utilized
for nuclear waste management studies (alpha radiolysis simulation with external beam). A project of boron capture
enhance fast neutron therapy is also under progress.
98

2005 COUNTRY: FRANCE FRA-3
[1] INSTITUTE: Centro d'Exploration et de Recherche Medicales
par Emission de Positrons (CERMEP)
Cyclotron Biomedical de Lyon
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
G. Galy
P. Lanai
D. Comar
Positive ion YEAR OF:
59 Boulevard Pinel, F-69003 Lyon
+33 4 726 88600
Pierre.Mandrillon@aima.fr
+33 4 726 88610
Dr. D. Le Bars
Head of Radiochemistry
(I) INSTALLATION
MANUFACTURER: CGR-MeV (II) UPGRADE:
MODEL: Cypris 325
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 16 8 Yes No
Maximum beam available (µA) >50 >50
Typical beam employed (µA) 30 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
>15 4
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 18 F-FDG one per/month to one
per week.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Number
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
2
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1987
99
93

94
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
100
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: FRANCE FRA-4
[1] INSTITUTE: CERMEP – Imagerie du Vivant
Hopital Neurocardiologique
59 Bd Pinel
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
F - 69003 Lyon
+33 4 72 688600
secretariat@cermep.fr
POSITION:
Dr. Gimenez
Director
OTHER SENIOR STAFF:
Dr. D. Le Bars, Head of Radiochemistry Radiopharmacy
NAME/POSITION
Dr. L. Zimmer, Radiopharmacology Radiopharmacy
NAME/POSITION
Dr. S. Guillouet, Radiochemist
[3] TYPE OF
CYCLONE 18/9 YEAR OF: (I)
1999
CYCLOTRON:
INSTALLATION
MANUFACTURER:
MODEL:
IBA, s.a. (II) UPGRADE:
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 9 Yes No
Maximum beam available (µA) 80 40
Typical beam employed (µA) 15-35 5
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
production
h/week for
research
h/week for
maintenance
h/week for
applications
20-30
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
101
95

96
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 25-75 >95 0.5 50-100 Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 10 3/week Yes No Yes No
DOPA 6 1/week Yes No Yes No
MPPF 3 3/week Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methionine 2 1/week Yes No Yes No
Flumazenil 2 1/week Yes No Yes No
Raclopride 2 1/week Yes No Yes No
Diprenorphine 2 2/month Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 0.33 2/week
14 15
N(d, n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
[ 11 C]acetate, [ 11 C]MQNB, [ 11 C]PE2I; [ 18 F]FLT, [ 18 F]FCH, [ 18 F]NaF
102
Price/
GBq
Price/
GBq
Price/G
Bq
Price/G
Bq
Price/G
Bq

2005 COUNTRY FRANCE FRA-5
[1] INSTITUTE: CNRS CERI
45071 Orleans Cedex 02
TELEPHONE NO.:
E-MAIL ADDRESS:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
[3] TYPE OF CYCLOTRON
MANUFACTURER:
MODEL:
Compact
CGR-MeV
680
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
France
33 2 38 25 54 05
briaud@cnrs-orleans.fr
Joseph Briaud
Engineer
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 38 25 65 50 Yes No x
Maximum beam available (µA) 40 40 10 10
Typical beam employed (µA) 40 20 1 1
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week for
Hours/week for research Hours/week for Hours/week for
radioproduction
maintenance applications
65 2 30 8 25
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: 20 Proton therapy:
Physics: Neutron therapy: 15
Activation analysis: 10 Other (specify) 10
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes x No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 18 18
F by O (p, n) F
11
C
64
Cu
123
I
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
For the moment we deal with industrial partnerships the conditions of production and
delivery radionuclides(frequency, activityies,…).
Yes X No
Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No X
[10] out on-site?
[11] Type of imaging equipment available on-site Number of
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical
2
–Small animal
–Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No x
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1971
103
97

98
18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F Ye
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS:(e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)
104

2005 COUNTRY FRANCE FRA-6
[1] INSTITUTE: Advanced Accelerator Applications
20 rue Diesel
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
MODEL:
Negative ions, fixed
energy
General Electric
PETrace
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
01630 Saint-Genis-Pouilly France
+33-4-50993070
info@adacap.com
+33-4-50993071
Stefano Buono
President & CEO
Luca Maciocco/cyclotron engineer & researcher
Vincent Tadino/research radiochemist
Philippe Dasse/responsible radiopharmacist
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 16.5 Yes No
Maximum beam available (µA) 80
Typical beam employed (µA) 42
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week for
Hours/week for research Hours/week for Hours/week for
radionuclide production
maintenance applications
…… 30 10 8
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
F-MISO (2005)
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] Type of imaging equipment available on-site Number of
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
2003
105
99

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
100 106
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 160 98 1.6 2500 Ye
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 90 3/day Yes No Yes No
18
F-Choline 20 2/week Yes No Yes No
18
FLT 20 2/week Yes No Yes No
18
MPPF 10 1/week Yes No Yes No
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name (list) Yield on batch Frequency of Used on site Distribution/
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
124
I
Yes No Yes No
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Yes No Yes No
201 Tl Yes No Yes No
211 At Yes No Yes No
[17] COMMENTS:(e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)

13. GERMANY
2005 COUNTRY: GERMANY GER-1
[1] INSTITUTE: Cyclotron Laboratory
Forschungszentrum Karlsruhe Technik und Umwelt
Hauptabteilung Zyklotron
P.O. Box 3640, 76021 Karlsruhe
TELEPHONE NO.:
+49 7247 82 2433
E-MAIL ADDRESS:
Hermann.Schweickert@hzy.fzk.de
FAX NO.:
+49 7247 82 3156
[2] PERSON IN CHARGE:
Dr. H. Schweickert
POSITION:
Director, Cyclotron Laboratory
OTHER SENIOR STAFF:
Dr. V. Bechtold, in charge of Radioisotope Production
NAME/POSITION
Dr. P. Fehsenfeld, RTM, Radionuclide Technique
[3] TYPE OF
Negative ion YEAR OF: (I)
1984
CYCLOTRON:
INSTALLATION
MANUFACTURER: Cyclotron
Corporation
(II) UPGRADE: Continuous
MODEL: CP 42 H -
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 15-40 Yes No
Maximum beam available (µA) 200
Typical beam employed (µA) 100
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
140 50 70 when needed 20
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) TLA
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? To hospitals and industry
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
107
101

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
102 108
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 75-150 >95 Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 37 - 75 1/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Planned Yes No Yes No
94m
Tc Planned Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
175 1/day Yes No Yes No
124
I
3.7 1/week Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: GERMANY GER-2
[1] INSTITUTE: Cyclotron Laboratory
Forschungszentrum Karlsruhe Technik und Umwelt
Hauptabteilung Zyklotron
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
P.O. Box 3640, 76021 Karlsruhe
+49 7247 82 2433
Hermann.Schweickert@hzy.fzk.de
+49 7247 82 3156
Dr. H. Schweickert
Director, Cyclotron Laboratory
Dr. V. Bechtold, in charge of Radioisotope Production
Dr. P. Fehsenfeld, RTM, Radionuclide Technique in Mechanical
Engineering
Positive ion YEAR OF: (I)
INSTALLATION
1964
MANUFACTURER: AEG (II) UPGRADE: Continuous
MODEL:
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 52 104 Yes No
Maximum beam available (µA) 50 50
Typical beam employed (µA) 20 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
15 5 5 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
109
103

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
104 110
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F >95 Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At 1/week Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: GERMANY GER-3
[1] INSTITUTE: Eberhard-Karls-University Tübingen
Interdisciplinary PET Centre, Radiopharmacy
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
Röntgenweg 15, D-72076 Tübingen
+49 7071 29 87443
machulla@uni-tuebingen.de
+49 7071 29 5264
[2] PERSON IN CHARGE: Professor Dr. H.-Juergen Machulla
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Dr. rer. nat. C. Solbach
Dr. rer. nat. G. Reischl
Dipl.-Ing. A. Stahlschmidt
Negative ion YEAR OF: (I)
INSTALLATION
MANUFACTURER: GE (II) UPGRADE:
MODEL: PETtrace
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 16.5 8 Yes No
Maximum beam available (µA) 75
Typical beam employed (µA) 35-55 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
15-20 15-20 15-20 1 15-20
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 15-20 Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Katharinenhospital (Stuttgart) 4/week, Kernchemie (Mainz) 1/week, Dr. Hörr (Plochingen)
1/week, Universitätsklinikum RDI (München) 1/week
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
511 KeV coincidence 1
Gamma camera 2
Single photon tomography (SPET)
Positron emission tomography (PET)
2
–Clinical 2 PET and
PET/CT
–Small animal 1
–Plant biochemistry 0
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1995
111
105

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
106 112
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 18
O (p, n) F
20 18
Ne (d, α) F
16 18
O (α, d) F
75 95 0.6 1000 Yes
No
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/GBq
(list)
(GBq)
production
sales
if available
FDG 30 5/week Yes No Yes No
FLT 10 1/week Yes No Yes No
FAZA 10 1/week Yes No Yes No
FMISO 10 1/week Yes No Yes No
FEC 13 2/week Yes No Yes No Depends
on number
of patients:
~100
€/GBq
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/GBq
(list)
(GBq)
production
sales
if available
Raclopride 4 3/week Yes No Yes No
Methylphenidat 5 3/week Yes No Yes No
DASB 6 1/week Yes No Yes No
BTA-1 8 1/3 months Yes No Yes No
6-OH-BTA-1 6 1/3 months Yes No Yes No
Cholin 30 4/week Yes No Yes No Depends
on number
of patients:
~750
€/batch
Methionin 8 1/month Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/ Price/GBq
(list)
batch (GBq) production
sales
if available
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 12 1/3month
14 15
N(d, n ) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y 1 2/month Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
0.4 1/month Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/GBq
if available
Price/GBq
if available

2005 COUNTRY: GERMANY GER-4
[1] INSTITUTE: Euro-PET GmbH
Hugstetlerstrasse 55
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
NAME/POSITIO
D-79106 Freiburg
+49 761 270 9204
Euro.PET@compuserve.com
+49 761 270 9200
Professor Dr. Peter Reuland
Dr. Ursula Sahm, Chief Chemist
Kenneth Stalmo, Technician
Bernd Morasch, Chemist
Dagmar Hentschel, Engineer
[3] TYPE OF
Negative Ion YEAR OF: (I)
1996
CYCLOTRON:
INSTALLATION
MANUFACTURER: GE. (II) UPGRADE:
MODEL: PET Trace
[4] CYCLOTRON CHARACTERISTICS: …….
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) Yes No
Maximum beam available (µA) 75 75
Typical beam employed (µA) 40 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
3 0.25
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11 15
C-carbon monoxide and carbon dioxide, O–water, carbon monoxide and oxygen.
[9] Do you supply radionuclides to other institutions? To different institutions
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET) 2
- Clinical
- Small animal
- Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
113
107

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
108 114
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 110 >95 1.2 1000 Ye
No
20 Ne (d, α) 18 F 25
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 35-45 8-10/week Yes No Yes No
Fluoride Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
(see comments) Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Yes No Yes No
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
13
NH3 10-13 10/year Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
N2 13 O 8-10 50/year
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY GERMANY GER – 5
[1] INSTITUTE: Forschungszentrum Rossendorf
Institut fuer Bioanorganische und Radiopharmazeutische Chemie
P.O Box 51 01 19
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OFCYCLOTRON:
MANUFACTURER:
MODEL:
Negative ion
IBA, Belgium
CYCLONE 18/9
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
01314 Dresden, Germany
+49 (0) 351 260 3170
s.steinbach@fz-rossendorf.de
+49 (0) 351 260 3232
Prof. Dr. habil. Joerg Steinbach
Director of the Institute
Dr. Frank Wuest, Head of PET Tracer Dept.
Dipl.-Ing. Stephan Preusche, Head of PET Cyclotron Unit
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 18 9 ----- ----- Yes X No
Maximum beam available (µA) 35 20 Possible for
1 H, 2 H; not
used
Typical beam employed (µA) 30 15-18
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week
for radionuclide
3 He
4 He
Hours/week for research Hours/week for
maintenance
1996
Hours/week for
applications
13-25
production
13-25 for PET
routine and R&D
3
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: --------- Radiography: ---------
Materials science: --------- Proton therapy: ---------
Physics: --------- Neutron therapy: ---------
Activation analysis: --------- Other (specify): RN
production
13-25
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes X No
56
Co (1-2)/year
some kBq
Mössbauer sources? (specify which & quantity) Yes No X
X ray sources? (specify which & quantity) Yes No X
Intense neutron beam? (specify average En = ?) Yes No X
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes X No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes X No
[11] Type of imaging equipment available on-site
511 KeV coincidence
Number of
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
1
– Clinical, Small animal , Plant biochemistry 1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No X
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No X
[14] Is the cyclotron used for targetry development? Yes X No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes X No
[16] Does your institute accept IAEA research fellows for training/experience? Yes X No
115
109

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
110 116
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O(p, n) 18 F 60-90 97 1.4 ml 300 Yes X
No
20 Ne(d, α) 18 F 8-11 600 ml Ne/F2
16 18
O(α, x) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
[ 18 F]FDG 33-45 1/day Yes X No Yes X No
[ 18 F]FDOPA 1.2 2/week Yes X No Yes X No
[ 18 F]3-O- 1.2 2/week Yes X No Yes No X
Methyl-FDOPA
[ 18 F]NAF 1/week Yes X No Yes No X
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
[ 11 C]Acetate 12-15 2/week Yes X No Yes No X
Various
research
products
on request Yes X No Yes No X
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Currently not
used
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
[ 15 O]H2O 5-6 2/month
14 15
N(d,n) O
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y 1.1 2/month Yes X No Yes X No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS:(e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Our internet home pages: Forschungszentrum Rossendorf: http://www.fz-rossendorf.de
Institut für Bioanorganische und Radiopharmazeutische Chemie: http://www.fz-rossendorf.de/pls/rois/Cms?pNid=130
CYCLONE 18/9 and 10/5 USER COMMUNITY: http://www.fz-rossendorf.de/pls/rois/Cms?pNid=531

2005 COUNTRY: GERMANY GER-6
[1] INSTITUTE: Forschungszentrum Rossendorf
Institut für Bioanorganische und
Radiopharmazische Chemie
P.O. Box 510119, 01314 Dresden
TELEPHONE NO.:
+49 351 260 3170
E-MAIL ADDRESS:
b.johannsen@fz-rossendorf.de
FAX NO.:
+49 351 260 3232
[2] PERSON IN CHARGE:
Professor habil. Bernd Johannsen
POSITION:
Director of the Institute
OTHER SENIOR STAFF:
F. Wuest, Head of PET Tracer Department
NAME/POSITION
St. Preusche, Head of Cyclotron Unit
[3] TYPE OF
U-120 YEAR OF: (I)
1958
CYCLOTRON:
INSTALLATION
MANUFACTURER:
MODEL:
NIIEFA St.
Petersburg
(II) UPGRADE: 1989
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 7 14 28 Yes No
Maximum beam available (µA)
Typical beam employed (µA) 50 50 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
production
research
maintenance
h/week for
applications
50 10 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? External application of
radionuclides generally
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
117
111

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
112 118
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: GERMANY GER-7
[1] INSTITUTE: German Cancer Research Centre (DKFZ)
Im Neuenheimer Feld 280
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Isochronous,
D-69120 Heidelberg
+49 6221 550 3
g.wolber@dkfz.de
+49 6221 422 572
Dr. Gerd Wolber, Head, Cyclotron Operation Group
Professor Dr. Wolfhard Semmler, Head – Biophysics
Professor Dr. Michael Eisenhut, Head – Radiochemistry
YEAR OF: (I)
1991
CYCLOTRON: negative ion
INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL: MC 32 NI
[4] CYCLOTRON CHARACTERISTICS: Average magnetic field: 1.59 T; pole face diam.: 135 cm; accel. freq: 24.3 MHz;
2 Dees 90º; dual cold cathode ion source; total weight: 53 tons; total power dissipation: 185 kva.
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 16-32 8-16 Yes No
Maximum beam available (µA) 100 100
Typical beam employed (µA) 30 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
50 (aver), 1997-2000 25 15 2-5 45
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 1 Radiography:
Materials science: 2-3 Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) Neutron dosimetry - 2
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No 140 Pr
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No εn= 14MeV
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
see comments
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Dept. of Nuclear Medicine,
Radiological Clinic of the University of Heidelberg; daily
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Both
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 1
� Single photon tomography (SPET) 1
� Positron emission tomography (PET) 1
– Clinical 1
– Small animal planned
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
119
113

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
114 120
% Isotopic
enrichment
18 O used
18 18
O (p, n) F 50-70 >95 1 16 at 30
bar
20 18
Ne (d, α) F 20-30
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
300 1 Ye
No
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 15-20 1-2/day Yes No Yes No
FLT 1.7 on demand Yes No Yes No
Others, see
Yes No Yes No
comments Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Others, see
Yes No Yes No
comments Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 5-6 2-3/week
14 15
N(d, n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu rare Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
in preparation Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
18
F – DOPA, FU, FET, 2F-Throsine,Choline
11
C – AIB, ethanole, doxorubicine, dacarbacine, acetate, choline
In preparation : Iodinated compounds ( 124 I, 121 I)
140 Pr ( 20%β +,via 141 Pr (p, 2n) 140 Nd is used for calibration of PET systems.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: GERMANY GER-8
[1] INSTITUTE: Herz- und Diabeteszentrum NRW
Universitaetsklinik der Ruhr-Universitaet Bochum
Institut für Molekulare Biophysik, Radiopharmazie u.
Nuklearmedizin
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
Georgstrasse 11. D-32535 Bad Oeynhausen
+49 5731 97 1308
wburchert@hdz-nrw.de/phadjilazaros@hdznrw.de/hhenneken@hdz-nrw.de
+49 5731 97 1819
Professor W. Burchert
Director of Institute
Ms. Petra Hadjilazaros (responsible for cyclotron operation)
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Mr. Harald Henneken
[3] TYPE OF
Negative Ion YEAR OF: (I)
1994
CYCLOTRON:
INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 18/9
[4] CYCLOTRON CHARACTERISTICS:
d P
3
He
4
He Dual Beams
Beam energies (MeV) 9 18 Yes No
Maximum beam available (µA) 40 80
Typical beam employed (µA) 5 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20 20 2 days quarterly
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
4-[18F]-FBA (in vivo identification and quantification of apoptotic cells with PET)
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 4
� Single photon tomography (SPET) 3
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
121
115

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
116 122
% Isotopic
enrichment
18 O used
18 18
O (p, n) F 25
95 1
20 18
Ne (d, α) F
16 18
O (α, d) F
50
1.6
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
400 Ye
No
Used on site Distribution/
(list)
(GBq)
production
sales
18
F-FDG 20 5-7 syntheses/week Yes No Yes No
18
F-Fluorine 5 10/year Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Acetate 3.7 4/week Yes No Yes No
MHED 2.6 2/month Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 4.5 4/day
16 13
O(p, α ) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 3 6/week
14 15
N(d,n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: GERMANY GER-9
[1] INSTITUTE: Institut für Nuklearchemie
Forschungszentrum Jülich GmbH
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
D-52425 Juelich
+49 2461 614141
s.m.qaim@fz-juelich.de
+49 2461 612535
Professor H.H. Coenen
Professor S.M. Qaim
Dr. M. Holschbach
[3] TYPE OF
Fixed energy, two YEAR OF: (I)
1997
CYCLOTRON: particle
INSTALLATION
MANUFACTURER: General Electric (II) UPGRADE: 1999
MODEL: PET Trace
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 16.5 8.4 Yes No
Maximum beam available (µA)
Typical beam employed (µA) 40 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
30 30 4
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET) 1
� Positron emission tomography (PET)
– Clinical 2
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.?
(radiochemistry)
Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
123
117

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
118 124
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Ye
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Flumazenil 3 2/week Yes No Yes No
Raclopride 3 2/week Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 15 daily
14 15
N(d, n) O
Butanol 5 daily
14 15
N(d, n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: GERMANY GER-10
[1] INSTITUTE: Institut für Nuklearchemie
Forschungszentrum Jülich GmbH
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
D-52425 Juelich
+49 2461 614141
s.m.qaim@fz-juelich.de
+49 2461 612535
Professor H.H. Coenen
Professor S.M. Qaim
Dr. J. Ermert
[3] TYPE OF
Baby Cyclotron
Dr. K. Hamacher
YEAR OF: (I)
1987
CYCLOTRON:
INSTALLATION
MANUFACTURER: Japan Steel Works,
Ltd.
(II) UPGRADE:
MODEL: BC 1710
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
17 10 Yes No
Typical beam employed (µA) 30 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
35 20 15 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET) 1
� Positron emission tomography (PET)
– Clinical 2
– Small animal 1
– Plant biochemistry 1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.?
(radiochemistry)
Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
125
119

18F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
120 126
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 60 96 1.5 200 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 30 4/week Yes No Yes No
CPFPX 15 1/week Yes No Yes No
FET 15 occasionally Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methionine 1-3 occasionally Yes No Yes No
Flumazenil 1-3 occasionally Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 1 occasionally
16 13
O(p, α ) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/GBq
if available
Price/GBq
if available
Price/GBq
if available
Price/GBq
if available
Price/GBq
if available

2005 COUNTRY: GERMANY GER-11
[1] INSTITUTE: Institut für Nuklearchemie
Forschungszentrum Jülich GmbH
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Variable energy
CYCLOTRON: compact
MANUFACTURER: The Cyclotron
Corporation
MODEL: CV 28
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
D-52425 Juelich
+49 2461 614141
s.m.qaim@fz-juelich.de
+49 2461 612535
Professor H.H. Coenen
Professor S. Qaim
Dr. B. Scholten
YEAR OF:
(I) INSTALLATION
1976
(II) UPGRADE: 1986, 1991, 1997
Dual Beams
Beam energies (MeV) 6-22 4-14 18-36 10-28 Yes No
Maximum beam available (µA) 30 20 10 20
Typical beam employed (µA) 30 20 10 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
56 12 16 7
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: 28 Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 86 Y, 94m Tc and 12y I to several
clinics under co-operative research
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET) 1
� Positron emission tomography (PET)
– Clinical 2
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
127
121

18F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
122 128
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 35 95 50 5 Yes
No
20 Ne (d, α) 18 F 15
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y 2 on demand Yes No Yes No
94m
Tc 2 on demand Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
0.5 ½ weeks Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: GERMANY GER-12
[1] INSTITUTE: Institute for Medical Radiation Physics
Hufelandstrasse 55
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Positive Ion, sector-
CYCLOTRON: focused
MANUFACTURER: The Cyclotron
Corporation
MODEL: CV 28
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
D-45122 Essen
+49 201 723 4182
+49 201 723 5907
Professor Dr. A. Bochisch
Director
G. Hudepohl, Technician/Engineer
YEAR OF: (I)
INSTALLATION
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 24 14 36 28 Yes No
Maximum beam available (µA) 100 100 50 50
Typical beam employed (µA) 100 100 50 50
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
40 20 10 5 Neutrons 5 patient
treatment
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: research 5 Radiography:
Materials science: Proton therapy:
Physics: research 5 Neutron therapy: 5
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1975
129
123

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
124 130
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 18
O (p, n) F
16 3 18
O ( He,p) F
20 18
Ne (d, α) F
16 18
O (α, d) F
37
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 18.5 3/week Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
11
CO2 37 2/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
O 2 15/min 3/week
14 15
N(din) O
CO2 15/min 3/week
14 15
N(din) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y temporary Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
7.4 temporary Yes No Yes No
124
I
3.7 temporary Yes No Yes No
201
Tl Yes No Yes No
211
At temporary Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Yes
No
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: GERMANY GER-13
[1] INSTITUTE: Institute of Radiology and Nuclear Medicine
Adickes-Allee 51-53
60322 Frankfurt am Main
TELEPHONE NO.:
E-MAIL ADDRESS:
+49 69 95961 626
FAX NO.:
+49 69 95961 630
[2] PERSON IN CHARGE:
POSITION:
Professor G. Hoer
OTHER SENIOR STAFF:
NAME/POSITION
Dr. W.T. Kranert
[3] TYPE OF
Negative ion H YEAR OF: (I)
1998
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI. (II) UPGRADE:
MODEL: RDS 111
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
40 20 15 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) Nuclide production for
Nuclear Medicine
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
94m Tc, 124 I
[9] Do you supply radionuclides to other If yes and available, name of institution/s & Yes No
institutions?
how often? We can give addresses, after
the cyclotron is established.
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 1
� Gamma camera 3
� Single photon tomography (SPET) 2
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
131
125

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
126 132
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 80 0.8 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 40 1/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
CO 5 1/week Yes No Yes No
CO2 5 1/week Yes No Yes No
Amino acids 5 1/week Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 5 2/week Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 1/week
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
The cyclotron is not established so far.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: GERMANY GER-14
[1] INSTITUTE: Max-Planck-Institut fuer Neurologische Forschung
Gleueler Strasse 50
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
D-50931 Koeln (Lindenthal)
+49 221 4726 220
wdh@pet.mpin-koeln.mpg.de
+49 221 4726 298
Professor Wolf-Dieter Heiss
Director
Professor Dr. Klaus Wienhard
[3] TYPE OF
Baby cyclotron YEAR OF: (I)
1987
CYCLOTRON:
INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE: 2005
MODEL: MC 16
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 17 8.5 Yes No
Maximum beam available (µA) 50 50
Typical beam employed (µA) 25 25
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20 20 4
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other If yes and available, name of institution/s & Yes No
institutions?
how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� Positron emission tomography (PET)
– Clinical 3
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
133
127

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
128 134
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 15 95 1.2 100 Yes
No
20 Ne (d, α) 18 F 10
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 10 4/week Yes No Yes No
Dopa 1 2/week Yes No Yes No
FLT 1 1/week Yes X No Yes No X
FHBG 1 1/week Yes X No Yes No X
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methionine 12 3/week Yes No Yes No
Raclopride 5 2/week Yes No Yes No
Flumazenil 10 1/week Yes No Yes No
MPHA 8 1/week Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 6 25/week
14 15
N(d,n) O
CO 5 1/month
14 15
N(din) O
O2 5 3/month
14 15
N(din) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced):
124 I – FIAU with 124 I from outside.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY GERMANY GER-15
[1] INSTITUTE: Medizinische Hochschule Hannover
Klinik für Nuklearmedizin
TELEPHONE NO.:
E-MAIL ADDRESS:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
MODEL:
Isochronous,
Scanditronix
MC 35
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Carl-Neuberg-Str. 1, D-30625 Hannover
+49 (0) 511 532 3085
Helmeke.Hans-J@MH-Hannover.de
Dr. Helmeke
Head of the Cyclotron Group
Prof. Dr. W.H. Knapp / Director of Nuclear Medicine
Prof. Dr. G.J. Meyer / Head of the Radiopharmazie Group
YEAR OF:
(I) INSTALLATION:
1976/77
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 7,5-35 3,8-18 5,6-47 7,5-35 Yes No X
Maximum beam available (µA) 50 50 20 20
Typical beam employed (µA) 30-40 30 15
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week
for radionuclide
production
3 He
4 He
Hours/week for research Hours/week for
maintenance
Hours/week for
applications
18,5 (incl. stand by) 17 1,5 6
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No x
Mössbauer sources? (specify which & quantity) Yes No x
X ray sources? (specify which & quantity) Yes No x
Intense neutron beam? (specify average En = ?) Yes No x
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No X
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes X No
out on-site?
[11] Type of imaging equipment available on-site Number of
� 511 KeV coincidence 1
� Gamma camera 3
� Single photon tomography (SPET) 5
� Positron emission tomography (PET)
– Clinical 2
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No X
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No X
[14] Is the cyclotron used for targetry development? Yes X No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No X
[16] Does your institute accept IAEA research fellows for training/experience? Yes No X
135
129

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
130 136
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 20 - 40 85-97 1,5 ml 200 Yes X
No
Ne (d, α) 18 F 1,8
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
F-FDG 9-20 5 / week Yes X No Yes X No
18
F-dopa 0,6 1 / week Yes X No Yes No X
18
F-NaF 4 2 / week Yes X No Yes No X
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
11
C-acetic acid 6-10 2 / week Yes X No Yes No X
11
C-methionine 2-5 1 / week Yes X No Yes No X
11
C-m-Hed 0,5-1,5 1 / week Yes X No Yes No X
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
15
O[H2O] 0,15 2 / week
14 15
N(d,n) O
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At up to 0,16 1-2/week Yes X No Yes X No
[17] COMMENTS: (e.g., you may add names of additional labelled compounds/ radiopharmaceuticals being produced)

2005 COUNTRY GERMANY GER-16
[1] INSTITUTE: Klinik für Nuklearmedizin
Universitätsklinikum Aachen
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
Pauwelsstraße 30 . 52057 Aachen . Germany
+49 241 80 88740
ubuell@ukaachen.de
+49 241 80 82520
Univ.Prof. Dr.med. Dr.med.habil. Udalrich Büll
OTHER SENIOR STAFF: Dr.rer.physiol. Berthold Müller
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
MODEL:
Negative Ion
CTI, Inc.
RDS 111
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No ⎩
Maximum beam available (µA) 50
Typical beam employed (µA) 25
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week
for radionuclide
production
Hours/week for research Hours/week for
maintenance
1997
Hours/week for
applications
22 20 2 -
[6] CYCLOTRON APPLICATIONS: Hours/week --- none --- Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No ⎩
Mössbauer sources? (specify which & quantity) Yes No ⎩
X ray sources? (specify which & quantity) Yes No ⎩
Intense neutron beam? (specify average En = ?) Yes No ⎩
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11
C
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No ⎩
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes ⎩ No
out on-site?
[11] Type of imaging equipment available on-site Number of
� 511 KeV coincidence
� Gamma camera (planar) 2
� Single photon tomography (SPET) 3
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No ⎩
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No ⎩
[14] Is the cyclotron used for targetry development? Yes No ⎩
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No ⎩
[16] Does your institute accept IAEA research fellows for training/experience? Yes No ⎩
137
131

18 F RADIONUCLIDE PRODUCTION --- none ---
Production Typical
production
yield (GBq)
132 138
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED --- none ---
Name
(list)
Yield on batch
(GBq)
Frequency of
production
11 C RADIOPHARMACEUTICALS PRODUCED --- none ---
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
[ 13 N]NH4 + 4 50 (per month) 16 13
O (p,α) N Yes No ⎩
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
[ 15 O]H2O 1 20 (per day)
15 15
N (p,n) O
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED --- none ---
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Aachen, 2005-09-28 B.Müller

2005 COUNTRY GERMANY GER-17
[1] INSTITUTE: Klinikum Rechts der Isar der Technischen Universitaet
Muenchen, Nuklearmedizinische Klinik und Poliklinik
Ismaninger Strasse 22
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
MODEL:
Siemens / CTI
RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
D-81675 Muenchen / Germany
+49 (0)89 4140-2972
M.Schwaiger@lrz.tu-muenchen.de
+49 (0)89 4140-4841
Markus Schwaiger, MD
Director
Hans-Jürgen Wester, PhD / Radiopharm. Chemistry
Ingo Wolf, PhD / Targeting
Michael Herz / FDG Production
Petra Watzlowik / PET Tracer Production
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 10.5 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 30 - 40
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week for
Hours/week for research Hours/week for Hours/week for
radioproduction
maintenance applications
16 16 — 2 —
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] Type of imaging equipment available on-site Number of
511 KeV coincidence —
Gamma camera 1
Single photon tomography (SPET)
Positron emission tomography (PET)
4
–Clinical 2
–Small animal
–Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1992
—
139
133

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
134 140
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 45 97 0.7 700 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 20.0 3 / day Yes No Yes No
FLT 0.75 1 / week Yes No Yes No
FET 3.0 2 / week Yes No Yes No
RGD 0.75 2 / month Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
methionine 2.6 2 / week Yes No Yes No
choline 6.0 3 / week Yes No Yes No
flumazenil 1.5 1 / month Yes No Yes No
BTA 1.2 1 / week Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
13
NH3 1.2 4 / week
16 13
O(p,α) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
H2 15 O 1.2 2 / month
Price/
GBqe
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS:(e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)
11
C-hydroxyephedrine 2.2 GBq 1 / month
11 C-diprenorphine 0.9 GBq
18 F-octreotide 0.5 GBq 1 / week
18 F-fluoride 1.2 GBq 1 / month

2005 COUNTRY: GERMANY GER-18
[1] INSTITUTE: Universitätsklinikum Hamburg-Eppendorf
Klinik u. Poliklinik für Radiologie, Abteilung für
Nuklaermedizin, Bereich Zyklotron u. Radiopharmazie
Luruper Chaussee 149
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
D-22761 Hamburg
+49 40 8998 2968
bruno@ukezyk.desy.de
+49 40 8998 2960
Dr. Pal Mikecz
Head
Uve Kirchner
Dr. Oliver Schulze
Isochronous YEAR OF: (I)
INSTALLATION
MANUFACTURER: Philips (II) UPGRADE:
MODEL: 140/IV
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 30 16 42 30 Yes No
Maximum beam available (µA) 130(internal)
Typical beam employed (µA) 20(external)
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research maintenance applications
40 30 2 8
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 5-7/week
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for agricultural
applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1968
141
135

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
136 142
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 28 75-95 0.9 500 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 15 10/week Yes No Yes No
18FLT 1-5 1 Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
McN 5652z 1-3 4/week Yes No Yes No
Choline 1 1 Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: GERMANY GER-19
[1] INSTITUTE: Universitätsklinikum Ulm, Abteilung Nukleamedizin
Robert-Koch-Strasse 8
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
D-89081 Ulm
+49 731 500 24981
bernd.neumaier@medizin.uni-ulm
+49 731 500 24979
Dr. Bernd Neumaier
Head of PET Chemistry
Dr. Andreas Vogg, Radiochemist
Christoph Solbach, Radiochemist
Dr. Michaela Schmid, Chemist
Negative ion YEAR OF: (I)
INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 18/9
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 18 9 Yes No
Maximum beam available (µA) 40 20
Typical beam employed (µA) 30 15
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
20 16 3 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) 20
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
Research, still not specified.
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Munich, Nuklearneclizimsche
und Polikline, KRI & in cases of cyclotron maintenance
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
e.g. with FLP, FDOpa
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 5
� Single photon tomography (SPET) 2
� Positron emission tomography (PET)
– Clinical 2
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience?
The candidate can only visit our cyclotron site, self-operation is impossible.
Yes No
3 He
4 He
1994
143
137

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
138 144
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 50 95 2 600 Yes
No
20 Ne (d, α) 18 F 6 21
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 22 4/week Yes No Yes No
Dopa 0.8 2/week Yes No Yes No
FLT 3 1/week Yes No Yes No
Fluoride 6 1/week Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methionine 7 2/week Yes No Yes No
Acetate 2.5 2/week Yes No Yes No
Raclopride 4 2/week Yes No Yes No
PK11195 1 0-1/week Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonic 16 0/week 16
O(p,α) Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 8 0/week
14
N(din)
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced):
18F micliosides by electrophilic fluorination. 0.4GBq, occasionaly for research
11
C chlorine, 6GBq/batch, 0.1/week
11
C alpha-methyl-tryptophane, 1.5 GBq/batch, 0.1/week
11 C carfentanil, 4GBq/batch, 0-1/week
11 C flumazenile, 4GBq/batch, 0.1/week.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: GERMANY GER-20
[1] INSTITUTE: Universitätsklinikum Ulm
Abteilung Nukleamedizin
Robert-Koch-Strasse 8
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
1994 TYPE OF
CYCLOTRON:
D-89081 Ulm
+49 731 500 24981
bernd.neumaier@medizin.uni-ulm
+49 731 500 24979
Dr. Bernd Neumaier
Head of Cyclotron / Radiopharmacy
Dr. Andreas Vogg, Radiochemist
Wolfgang Scheel, Cyclotron Engineer
Dr. Michaela Schmid, Chemist
Negative ion YEAR OF: (I)
INSTALLATION
MANUFACTURER: GE Medical Systems. (II) UPGRADE:
MODEL: PETtrace
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
3 He
4 He
07 / 2002
Dual Beams
Beam energies (MeV) 16.5 8.4 Yes No
Maximum beam available (µA) 75 30
Typical beam employed (µA) 35 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
25 h 20 h 5 h 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) Radpharm 25
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
Research, still not specified.
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
e.g. with FLP, FDOpa
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 5
� Single photon tomography (SPET) 2
� Positron emission tomography (PET)
– Clinical 3
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience?
The candidate can only visit our cyclotron site, self-operation is impossible.
Yes No
145
139

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
140 146
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 60 95 2 600 Yes
No
20 Ne (d, α) 18 F 10 21
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
FDG 26 4/week Yes No Yes No
DOPA 0.8 2/week Yes No Yes No
Fluoride 6 1/week Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methionine 7 2/week Yes No Yes No
Choline 9 9/week Yes No Yes No
Raclopride 2 1/week Yes No Yes No
BTA-1 2 2/week Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonic 16 0/week 16
O(p,α) Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 8 0/week
14
N(d,n)
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced):
11 C alpha-methyl-tryptophane, 1.5 GBq/batch, 1/week
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

COUNTRY: GERMANY GER-21
[1] INSTITUTE: University of Frankfurt
Department of Nuclear Medicine
Klinikum der Johann Wolfgang Goethe-Universität
Theodor-Stern-Kai 7, Jaus 21 D
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
D-60590 Frankfurt am Main
+49 69 6301 4330
christian.menzel@em.uni-frankfurt.de
+49 69 6301 6805
Professor Dr. Frank Grünwald
Chairman and Director
Professor Dr. Christian Menzel, Deputy Director
YEAR OF:
2002
CYCLOTRON:
(I) INSTALLATION
MANUFACTURER: (II) UPGRADE:
MODEL: PetTrace?
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
Typical beam employed (µA)
Yes No
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] RADIONUCLIDES AND RADIOPHARMACEUTICALS PLANNED TO BE PRODUCED IN THE NEXT 1-3 YEARS (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? …….
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 1
� Gamma camera 2
� Single photon tomography (SPET) 2
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
147
141

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
142 148
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: GERMANY GER-22
[1] INSTITUTE: Westfaelische Wilhelms Universitaet
Klinik und Poliklinik fuer Nuklearmedizin
Domagkestrasse 5
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
48189 Münster
+49 251 83 473 76 or 473 62
eckardt@uni-muenster.de
+49 251 83 473 63
Professor Dr. O. Schober
Director
Jörg Eckardt, Physicist
Dr. Markus Knickmeier, Chemist
Negative ion YEAR OF:
(I) INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 111
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 50
Typical beam employed (µA) 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
production
research
maintenance
11 10 1
3 He
4 He
1999
h/week for
applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 10 Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 3
� Single photon tomography (SPET) 3
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
149
143

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
144 150
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 40 97 1.1 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 20 Daily Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 2 weekly 15 N(p,n) 15 O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: GERMANY GER-23
[1] INSTITUTE: Zentralklinik Bad Berka GmbH
Bad Berka PETCT Centre
Robert-Koch-Allee 9
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
99437 Bad Berka, Germany
+49 364 585 2200
info@rpbaum.de
+49 364 585 3515
Professor Dr. Richard P. Baum
Chairman, Department of Nuclear Medicine/Centre for PETCT
Negative ion
Dipl.-.Ing. R. Wortmann, Head of Radiopharmacy
YEAR OF:
CYCLOTRON:
(I) INSTALLATION
1997
MANUFACTURER: CTI, Inc. (II) UPGRADE: 1998/99 (Dual Beam)
MODEL: RDS 111
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 35
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
16
Installation underway
14 - 15
none
1-2
none
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: none Radiography: none
Materials science: none Proton therapy: none
Physics: none Neutron therapy: none
Activation analysis: none Other (specify) none
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11 13 15 18
C, N, O, F
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Hospitals in Germany, daily
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals caried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Number
Gamma camera 1
Single photon tomography (SPET) 1
Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
151
145

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
146 152
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 18
O (p, n) F > 3.4 GBq/µA > 95 0.8 500 Yes
20 18
Ne (d, α) F
16 18
O (α, d) F
34 - 120 GBq
No
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
18
FDG 20 - 70 daily Yes No Yes No
18
Fluoride 20 2/week Yes No Yes No
18
FET (Tyrosin) 4 1/week Yes No Yes No
18
FECh (Cholin) 4 1/week Yes No Yes No
11 C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
None Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
None Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
None
used
OTHER ISOTOPES PRODUCED
None
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Ga-68 DOTA-NOC, Y-90 DOTA-TATE, Lu177-DOTA-TATE
N-13 ammonia
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

14. HUNGARY
2005 COUNTRY: HUNGARY HUN-1
[1] INSTITUTE: Institute of Nuclear Research
of the Hungarian Academy of Sciences
Bem ter 18/c, P.O. Box 51
TELEPHONE NO.:
E-MAIL ADDRESS:
+36 52 417 266
FAX NO.:
+36 52 416 181
[2] PERSON IN CHARGE:
F. Tarkanyi
POSITION:
Head, Cyclotron Department
OTHER SENIOR STAFF:
Dr. L. Trón, Head of PET Centre
NAME/POSITION
Z. Kormany
NAME/POSITION
P. Kovacs
[3] TYPE OF
Compact isochronous YEAR OF: (I)
1985
CYCLOTRON:
INSTALLATION
MANUFACTURER: NIIEFA Russia (II) UPGRADE: 1997
MODEL: MGC 20E
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 20 10 26 20 Yes No
Maximum beam available (µA) 200 300 50 50
Typical beam employed (µA) 50 50 25 25
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
94 28 (56 every 2nd week) 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
13 15 11 111 123 123
N-Ammonia, O-Water, C-Flumezinil, In-DTPA, I-mIBG, I-Imoazine
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Na 123 I-every 2 weeks; 67 Ga-citric
acid – every 2 weeks.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
511 KeV coincidence 1
Gamma camera 2
Single photon tomography (SPET) 1
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
153
147

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
148 154
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Neutron source (radiobiology, radiation hardness test, neutron activation, Thin Layer Activation (TLA), wear
measurements, activation analysis (charged particle) Basic nuclear physics (in beam nuclear spectroscopy, astrophysical
nuclear reactions)

15. INDIA
2005 COUNTRY: INDIA IND-1
[1] INSTITUTE: Radiation Medicine Centre
Bhabha Atomic Research Centre (BARC)
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
Trombay, Mumbai 400 085
+91 22 550 5326
samuel@apsara.barc.ernet.in
+91 22 550 5326
Dr. A.M. Samuel
Director, Bio-Medical Group, BARC, Mumbai
Dr. N. Ramamoorthy
Chief Executive, BRIT, Mumbai
Dr. B.N. Karkers, Head, MD & PDS
Dr. M.R.A. Pillai, Head, Radiopharmaceuticals Division
Dr. N. Nair, Head, Radiation Medicine Centre
[3] TYPE OF
Medical YEAR OF: (I)
2001
CYCLOTRON:
INSTALLATION
MANUFACTURER: Wipro GE, Mumbai (II) UPGRADE:
MODEL: PET Trace
[4] CYCLOTRON CHARACTERISTICS: Dual particle (16.5 MeV Proton and e MeV Deuteron)
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 16.5 8.5 Yes No
Maximum beam available (µA) 80 80
Typical beam employed (µA) 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
10-12 10-12 Not yet decided
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions? If yes and available, name of
institution/s & how often? Planned to supply 18 F to Nuclear Medicine Departments
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 4
� Single photon tomography (SPET) 3
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
155
149

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
150 156
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
This is the first facility to be set up in the country with expertise in accelerations, radiopharmaceuticals, radiation biology
and nuclear medicine. It is anticipated that apart from the routine PET radiopharmaceuticals, research in the
development of new PET labeled compounds will be initiated.

2005 COUNTRY: INDIA IND-2
[1] INSTITUTE: Variable Energy Cyclotron Centre (VECC)
1/AF, Bidhan Nagar
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Sector-focused (pole
CYCLOTRON:
diameter 224 cm)
Calcutta - 700 064
+91 33 3371 230
+91 33 3346 871
Dr. B.C. Sinha
Director
YEAR OF: (I)
INSTALLATION
MANUFACTURER: VEC Centre (II) UPGRADE:
MODEL: (Individual design)
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 6.30 12.30 25.80 Yes No
Maximum beam available (µA) 200 200 200
Typical beam employed (µA) 20 20 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
160 24 8
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
201
Tl
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Regional Radiation Medicine
Centre, Thakurpukur, Calcutta – weekly, Radiation Medicine Centre Mumbai - monthly
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1997
157
151

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
152 158
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

16. INDONESIA
2005 COUNTRY: INDONESIA INS-1
[1] INSTITUTE: National Atomic Energy Agency, BATAN
PPR-Batan Kawasan
TELEPHONE NO.:
E-MAIL ADDRESS:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Positive ion
Puspiptek Serpong 15310
+21 756 3141
mutalib_a@yahoo.com
Mr. Silakhuddin
Head, Cyclotron Division
Mr. Tonny Heryanto
Budi Tarigan
YEAR OF: (I) INSTALLATION 1990
MANUFACTURER: CTI, Inc. (II) UPGRADE: 1995 (modified to negative
ion by IBA)
MODEL: CS 30
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 24-27 Yes No
Maximum beam available (µA) 60
Typical beam employed (µA) 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
6 4 2 2 2
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
We would like to produce 123 I. Unfortunately we have no experts and facility.
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Hospitals, 1-2/week
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
159
153

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
154 160
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl 1/2week Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
We are planning to produce 18 FDG in 2002.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

17. IRAN, ISLAMIC REPUBLIC OF
COUNTRY: IRAN IRA-1
[1] INSTITUTE: Nuclear Research Centre for Agriculture
and Medicine (NRCAM)
P.O. Box 31585-4395, Karaj
TELEPHONE NO.:
E-MAIL ADDRESS:
+98 261 313 0676
FAX NO.:
+98 261 411 105
[2] PERSON IN CHARGE:
POSITION:
Professor Hossein Afarideh
OTHER SENIOR STAFF:
Satari; Partovi
NAME/POSITION
Rafii; Akbari; Shafiei
[3] TYPE OF
Negative ion YEAR OF: (I)
1995
CYCLOTRON:
INSTALLATION
MANUFACTURER: IBA, Belgium (II) UPGRADE:
MODEL: Cyclone 30
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
15-30 7-15 Yes No
Typical beam employed (µA) 500 150 175
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20-25 12-17 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
81m Kr – Rb generator, 18 F – FDG , 123 In
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? To all nuclear medicine centres –
Once a week
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
161
155

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
156 162
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga 0.1 0.5/week Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In 0.5 0.5/week Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl 0.037 1/week Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

18. ISRAEL
2005 COUNTRY: ISRAEL ISR-1
[1] INSTITUTE: Hadassah Medical Organization
Ein Karem
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
Il-91 120 Jerusalem
+972 2 6777 197
mishani@md2.huji.ac.il
+972 2 6438 506
Dr. Eyal Mishani
Head of Cyclotron Unit
Mr. Desideriu Laky, Cyclotron Operator
Dr. Revital ben-Daniel, Research
Mr. Daniel Wajnblum, Engineer
[3] TYPE OF
Negative ion YEAR OF: (I)
1997
CYCLOTRON:
INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 18/9
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 9 Yes No
Maximum beam available (µA) 40 25
Typical beam employed (µA) 30 18
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
18 12 6 12
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 4 Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 F – FDG, DOPA, 18 F – FES; 18 F –FLT; 11 C – Choline ; 15 O - Water
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 2
� Gamma camera 2
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
163
157

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
158 164
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 110 97 2.3 900 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 50 2-3/day Yes No Yes No
Dopa Yes No Yes No
ML 01 Yes No Yes No
ML 03 Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Choline 10 Yes No Yes No
Deprenyl 3 Yes No Yes No
Methionine Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 8
16 13
O(p,α ) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 4 -8 1/week
14 15
N (d, n ) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: ISRAEL ISR-2
[1] INSTITUTE: Soreq NRC
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
NAME/POSITION
81800 Yavne
+97 2 8943 4615
shohet@mailbox.soreq.gov.il
+97 2 8943 4133
Engineer Yosef Shohet
Head of Facility
Dr. M.B. Goldberg, Head, Steering Committee
Dr. D. Berkovits, Chief Physicist
Bs. Phrm. B. Hoch, Chief Radiochemist
Mr. T. Arbel, Head of Operation Staff
[3] TYPE OF
Cyclone series YEAR OF: (I)
2000
CYCLOTRON:
INSTALLATION
MANUFACTURER: IBA, Belgium (II) UPGRADE:
MODEL: 10/5
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 10 5 Yes No
Maximum beam available (µA) 80 80
Typical beam employed (µA) 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20-25 15-20 1-2 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 15-20 Radiography:
Materials science: 1-2 Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11 66-68 15
C Ga F-DOPA
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
165
159

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
160 166
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 15000 94 2 600 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 50 1-2 Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

19. ITALY
2005 COUNTRY: ITALY ITA-1
[1] INSTITUTE: Azienda Ospedaliero Universitaria
Policlinico S. Orsola - Malpighi
Via Massarenti, 9
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
40138 Bologna
+39 051 636 3952
marengo@med.unibo.it
+39 051 636 3954
Professor Roberto Franchi
Professor of Nuclear Medicine
Dr. Mario Marengo, Medical Physicist, Head Nuc. Med. Physics
Dr. Stefano Boschi, Chemist, Head Radiopharmacy
PETtrace YEAR OF: (I)
2001
CYCLOTRON:
INSTALLATION
MANUFACTURER:
MODEL:
GE (II) UPGRADE:
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 16.5 8 Yes No
Maximum beam available (µA) 75 60
Typical beam employed (µA) 38 35
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
25 18 6 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify): 64Cu
[9] Do you supply radionuclides to other If yes and available, name of institution/s & Yes No
institutions?
how often? Hospitals of Cesena and Forlì,
daily
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Number
Gamma camera 5
Single photon tomography (SPET)
Positron emission tomography (PET)
5
– Clinical 2
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
167
161

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
162 168
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 100 >95 1.5 1000 Yes
No
20 Ne (d,α) 18 F 5.5 Ne+0.3 %F2 60
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of
Used on site Distribution/
(list)
(GBq)
production
sales
18
F - FDG 50 2/day Yes No Yes No
18 F - FDOPA 1 1 / week Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
11
C - Choline 26 1 / day Yes No Yes No
11 C - Methionie 26 1 / week Yes No Yes No
11 C - acetate 26 1 / week Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: ITALY ITA-2
[1] INSTITUTE: Azienda Ospedaliera 5. Maria Nuova
Servizio di Medicina Nucleare
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
V. le Risorgimento 80, Reggio Emilia
+39 0522 296 284
salvo.diana@asmn.re.it
+39 0522 296 392
Dr. Diana Salvo
Department Chief
OTHER SENIOR STAFF:
Dr. Annibale Versari
NAME/POSITION
chair of PET-Center activities
[3] TYPE OF
10 Mev YEAR OF: (I)
October 2001
CYCLOTRON:
INSTALLATION
MANUFACTURER: General Electric (II) UPGRADE:
MODEL: Minitrace
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 9.6 Yes No
Maximum beam available (µA) 50
Typical beam employed (µA) 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for
production
research
15 13 2
h/week for
maintenance
h/week for
applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
Maybe 11 C
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? In 2002
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 1
� Single photon tomography (SPET) 2
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
169
163

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
164 170
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 37 95 0.8 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of
Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 37 1or 2/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: ITALY ITA-3
[1] INSTITUTE: CNR Institute of Clinical Physiology
Via Moruzzi, 1
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
I-56100 Pisa
+39 050 315 3384
salvador@ifc.cnr.it
+39 050 315 2166
Piero A. Salvadori
Head – PET/Cyclotron Facility
Luca Menichetti, Radiopharmacist
Debora Petroni, Radiopharmacist
Michela Poli, Pharmacist
[3] TYPE OF
Negative ion YEAR OF: (I)
1996
CYCLOTRON:
INSTALLATION
MANUFACTURER: GE Medical Syst. (II) UPGRADE: 2001
MODEL: PET Trace
[4] CYCLOTRON CHARACTERISTICS: 5 beam ports used (6 available); targets resident on beam ports, no beam
transport lines.
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 16.7 8.4 Yes No
Maximum beam available (µA) 75 50
Typical beam employed (µA) 25 25
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
27 15 10 2
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
511 KeV coincidence
Gamma camera 3
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical 1
–Small animal planned
–Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
171
165

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
166 172
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 55 97 1 150 Yes
No
20 Ne (d, α) 18 F 11
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of
Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 11 1/day Yes No Yes No
Fluoride 3.7 2/week Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methyl iodide 37 Development Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 2 1/day Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
O Development
Water Development
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Development Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Development Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Development Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Additional activities planned for near future:
- use of cyclotron for research in Boron neutro capture therapy
- FDG manufacturing site
- research in molecular imaging applied to genomic and proteonomic.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: ITALY ITA-4
[1] INSTITUTE: Consiglio Nazionale delle Ricerche
Institute Pascale (CNR)
Via M. Semmola
I-80131 Napoli
TELEPHONE NO.:
E-MAIL ADDRESS:
+39 81 5903 528/527
FAX NO.:
+39 81 5465 797
[2] PERSON IN CHARGE:
POSITION:
Professor Marco Salvatore
OTHER SENIOR STAFF:
NAME/POSITION
Antonello Green
[3] TYPE OF
Positive ion YEAR OF: (I)
1991
CYCLOTRON:
INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL: MC 17
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 17 8.5 Yes No
Maximum beam available (µA) 75 50
Typical beam employed (µA) 50
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
40 15 25
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
15 O - Water , 11 C – CH3 I
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
173
167

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
168 174
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Fluoride Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Acetate Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: ITALY ITA-5
[1] INSTITUTE: Istituto Naziónale per lo Studío e la Çura dei Tumori
Via G. Venezian 1
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
I-20133 Milano
+39 2 2390 2220
bombardieri@istitutotumori.mi.it
+39 2 2367 874
Dr. Emilio Bombardieri
Director, Nuclear Medicine Department
Dr. Flavio Crippa, Co-ordinator, Clinical PET
Dr. Claudio Pascali, Co-ordinator, Radiopharmacy
Eng. Vinicio De Sanctis, Responsible for the Cyclotron
[3] TYPE OF
Positive ion YEAR OF: (I)
1995
CYCLOTRON:
INSTALLATION
MANUFACTURER: Scanditronix (II) UPGRADE:
MODEL: MC 17F
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 17 85 Yes No
Maximum beam available (µA) 50 50
Typical beam employed (µA) 25 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
12 6 6
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) PET 35
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other If yes and available, name of institution/s & Yes No
institutions?
how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
Number
–Clinical
–Small animal
–Plant biochemistry
9-10 patients/day
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
175
169

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
170 176
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 4500 94-97 ~ 1 250 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 10-15 1/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methionine 2 - 10 1/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: ITALY ITA-6
[1] INSTITUTE: Istituto Scientifico H. San Raffaele
Servizio di Medicina Nucleare
Via Olgettina, 60
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
I-20132 Milano
+39 02 2153 056
fazio@mednuc.hsr.it
Professor Ferruccio Fazio
Mario Matarrese
Francesco Perugini
[3] TYPE OF
Negative ion
Sergio Todde
YEAR OF: (I)
1988
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS: Negative hydrogen ions
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 25
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
27 20 5 2
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other If yes and available, name of institution/s & Yes No
institutions?
how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
511 KeV coincidence 1
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
5
–Clinical
–Small animal
–Plant biochemistry
3
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
177
171

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
172 178
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 26 > 94 0.65 500 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 13 2/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methyl choline 3 2/week Yes No Yes No
FE – CIT 1 2/week Yes No Yes No
Raclopride 1.5 1/week Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Water 370 MBq 3/week
15 N (p, n ) 15 O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: ITALY ITA-7
[1] INSTITUTE: Ospedale San Raffaele, Universita Degli Studi
Cattedra di Medicina Nucleare
Via Olgettina 60
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
I-20132 Milano
+39 2 2153056/2643/ 2716
fazio@mednuc.hsr.it
+39 2 2640390
Professor Ferruccio Fazio
Mario Matarrese, in charge of the Cyclotron
Francesco Perugini, in charge of Operations
Sergio Todde, in charge of Radiochemistry
[3] TYPE OF
Negative ion YEAR OF: (I)
2000
CYCLOTRON:
INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 18/9
[4] CYCLOTRON CHARACTERISTICS: Protons and deuterons beam.
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 9 Yes No
Maximum beam available (µA) 50 40
Typical beam employed (µA) 25 25
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
32 5 25 2
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other If yes and available, name of institution/s & Yes No
institutions?
how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
511 KeV coincidence 1
Gamma camera 5
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical 3
–Small animal
–Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
179
173

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
174 180
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 74 >94 2 700 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 37 1 run/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY ITALY ITA-8
[1] INSTITUTE: European Commission – Joint Research Centre
Institute for Health and Consumer Protection
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
MODEL:
Compact
Scanditronix
MC40
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Via E. Fermi 1, I-21020 Ispra (VA), Italy
+39-0332-785194
uwe.holzwarth@jrc.it
+39-0332-789385
Uwe Holzwarth
Technical Director
Kamel Abbas
Neil Gibson
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
3 He
4 He
1982
none to accelerator;
laboratory continuous
Dual Beams
Beam energies (MeV) 8-39 4-19.5 11-53 8-39 Yes No X
Maximum beam available (µA) 60 50 20 30
Typical beam employed (µA) 30 15 3 5
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week
for radionuclide
production
Hours/week for research Hours/week for
maintenance
Hours/week for
applications
70 35 20 5 10
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: 0 Radiography: 0
Materials science: 10 Proton therapy: 5
Physics: 5 Neutron therapy: 0
Activation analysis: 5 Other (Target developm.) 10
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No X
Mössbauer sources? (specify which & quantity) Yes No X
X ray sources? (specify which & quantity) Yes No X
Intense neutron beam? (specify average En = ?) Yes No X
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
Yes X No
If yes and available, name of institution/s & how often?
Istituto Nazionale di Fiscica Nucleare according to common project necessities
Istituto Europeo di Oncologia (start envisaged for 2006)
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
[11] Type of imaging equipment available on-site Number of
511 KeV coincidence 0
Gamma camera 0
Single photon tomography (SPET) 0
Positron emission tomography (PET), (PET-CT) 0
–Clinical 0
–Small animal 0
–Plant biochemistry 0
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No X
Yes No X
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes X No
[14] Is the cyclotron used for targetry development? Please, specify. Yes X No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes X No
[16] Does your institute accept IAEA research fellows for training/experience? Yes X No
181
175

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
176 182
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 100 95 1.5 ml Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 50 Yes No X Yes X No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu < 1 2/month Yes X No Yes X No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At < 1 1/month Yes X No Yes X No
[17] COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)
18
F-FDG production in collaboration with commercial partner that is in charge with distribution
(commercial data confidential) proton therapy: test and development of beam diagnostic equipment in collaborations
64 211
Cu and At: target development, alternative production routes, production capacity will increase
Distribution of 64 Cu and 211 At to collaboration partners in the nuclear and medical field for in vitro (later in vivo) studies;
studies with 211At have to start in our labs due to missing licenses for handling alpha-emitters in hospitals
CPAA for biokinetics studies on radioactive fallout components
TLA for release studies on biomedical materials and implants, as well as engine components

2005 COUNTRY ITALY ITA- 9
[1] INSTITUTE: U.O.Medicina Nucleare centro PET
Ospedale S.Giacomo via Ospedale n° 18 31033 Castelfranco
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
MODEL:
11 MeV
CTI
RDS 112
[4] CYCLOTRON CHARACTERISTICS:
MEDICAL CYCLOTRON
NEGATIVE IONS ACC.
1 H
2 H
Veneto Treviso, ITALY
+390423732435
franchierhome@tin.it
+390423732426
F.Chierichetti MD director of Nuclear Medicine Department
Head of PET center
Dr A.Fini, radiochmist
Dr M.Marcolin, radiopharmacist
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 10.5 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 28
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week for
Hours/week for research Hours/week for Hours/week for
radioproduction
maintenance applications
18 16 0 4 2
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) Clinical
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No X
Mössbauer sources? (specify which & quantity) Yes No X
X ray sources? (specify which & quantity) Yes No X
Intense neutron beam? (specify average En = ?) Yes No X
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18RFbFLT 18F MISO 18F DOPA
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
2 other regional institutios
Yes X No
[10] Are clinical medical research using cyclotron radiopharmaceuticals carried out on-site? Yes X No
[11] Type of imaging equipment available on-site Number of
511 KeV coincidence 0
Gamma camera 0
Single photon tomography (SPET) 2
Positron emission tomography (PET), (PET-CT) 1 PET
– Clinical, Small animal, Plant biochemistry 1 PET-TC
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No X
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No X
[14] Is the cyclotron used for targetry development? Please, specify. Yes No X
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes X No
[16] Does your institute accept IAEA research fellows for training/experience? Yes X No
3 He
4 He
1994
2002
183
177

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
178 184
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 37 >95 0.85 ml 800 gr Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 21 daily Yes X No Yes No X
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
11
C-Acetate 5 Twice a week Yes X No Yes No X
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
13
N-Ammonia 1.1 Twice a week
16 13
O ( p alfa ) N Yes No X
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 5.5 rare
15 15
N (p n ) O
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS: e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)

2005 COUNTRY: ITALY ITA-10
[1] INSTITUTE: Ospedale Maggiore di Milano
Servizio di Medicina Nucleare
Via Francesco Sforza 35
Pad. Granelli, I-20133 Milano
TELEPHONE NO.:
E-MAIL ADDRESS:
+39 02 5503 3340
FAX NO.:
+39 02 5503 5510
[2] PERSON IN CHARGE:
Dr. Paolo Gerundini Gherardi
POSITION:
OTHER SENIOR STAFF:
Primario
NAME/POSITION
Fabio Riccardo Colombo
NAME/POSITION
Rosangela Casati
[3] TYPE OF
PET Trace YEAR OF: (I)
2000
CYCLOTRON:
INSTALLATION
MANUFACTURER: (II) UPGRADE:
MODEL: PT GEMS
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 16.5 8.4 Yes No
Maximum beam available (µA) 75 60
Typical beam employed (µA) 25
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
10 8 2 2
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) PET
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
15 13 11
O - Water, N - Ammonia, C - Radiopharmaceuticals to be decided.
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 1
� Gamma camera 3
� Single photon tomography (SPET) 3
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
185
179

18F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
180 186
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 44.4 95 1.2 400 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 22.2 Daily Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY ITALY ITA-11
[1] INSTITUTE: Istituto Clinico Humanitas
Via Manzoni 56
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OFCYCLOTRON:
MANUFACTURER:
MODEL:
Cyclone
IBA
Cyclone 18/9
[4] CYCLOTRON CHARACTERISTICS:
PROTON BEAM 18 MEV
DEUTERON BEAM 9 MEV
1 H
2 H
20089 Rozzano (MI), Italy
+390282246622
medicina.nucleare@humanitas.it
+390282246691
Arturo Chiti
Director, Nuclear Medicine
Giovanni Tosi / Physicist
Katia Marzo/ Senior Radiochemist
Mauro Almangano / Junior Radiochemist
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 18 9 Yes No
Maximum beam available (µA) 80 35
Typical beam employed (µA) 30 25
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week for
radioproduction
3 He
4 He
Hours/week for research Hours/week for
maintenance
2003
Hours/week for
applications
12 12
[6] Cyclotron applications: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11C-choline; 11C-metionine; 13N-ammonia
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] Type of imaging equipment available on-site Number of
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET) 1
� Positron emission tomography (PET), (PET-CT) 1
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Please, specify. Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
187
181

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
182 188
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 18
O (p, n) F
Ne (d, α)
37 95 2000 µl
600 µl
18 F
16 18
O (α, x) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 14.8 2 / DAY Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Frequency of
production
18 O2 (l)
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Yes
No
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS:(e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)

2005 COUNTRY ITALY ITA-12
[1] INSTITUTE: AZIENDA OSPEDALIERA S. CROCE E CARLE - CUNEO
Via M Coppino 26
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
MODEL:
Self-shielded
GE Healthcare
MINItrace
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
12100 Cuneo , Italy
+39.0171.64.1690
fisici.mn@ospedale.cuneo.it
+39.0171.64.1554
Dr. Alberto Biggi
Head of Nuclear Medicine Dept
Dr. Gianni Perno, Physicist
Dr. Michelangelo Longo, Chemist
Ing. Roberto Giuliano. Chemist
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 9.6 Yes No X
Maximum beam available (µA) 35
Typical beam employed (µA) 30
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week
for radionuclide
production
3 He
2002
-
4 He
Hours/week for research Hours/week for
maintenance
Hours/week for
applications
9 8 0 1 0
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) Medical
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No X
Mössbauer sources? (specify which & quantity) Yes No X
X ray sources? (specify which & quantity) Yes No X
Intense neutron beam? (specify average En = ?) Yes No X
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11
C-Choline
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No X
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes X No
out on-site?
[11] Type of imaging equipment available on-site Number of
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET) 5
� Positron emission tomography (PET), (PET-CT)
– Clinical 1
– Small animal 0
– Plant biochemistry 0
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No X
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No X
[14] Is the cyclotron used for targetry development? Please, specify. Yes No X
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes X No
[16] Does your institute accept IAEA research fellows for training/experience? Yes X No
189
183

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
184 190
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 45 97 1 cc 300 Yes
No X
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 25 1/die Yes X No Yes No X
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
NH3 1 1/week 16 13
O (p, α) N Yes No X
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS:(e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)

2005 COUNTRY ITALY ITA-13
[1] INSTITUTE: A.O. CANNIZZARO
VIA MESSINA 829
TELEPHONE NO.:
E-MAIL ADDRESS:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:MO
DEL:
IBA
Cyclone 18/9
[4] CYCLOTRON CHARACTERISTICS:
1 H
95126 CATANIA (ITALY)
++ 30 095 7263588
sabini@lns.infn.it
Dr. M. Ippolito
MD/ head of Pet-Cyclotron Division
MG SABINI MEDICAL PHYSICIST
F. SCOPELLITI RADIOCHEMISTRY
P. DIRAIMONDO RADIOCHEMISTRY
YEAR OF:
(I) INSTALLATION:
2004
2 H
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 18 9 Yes x No
Maximum beam available (µA) 80 35
Typical beam employed (µA) 40 20
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week for
Hours/week for research Hours/week for Hours/week for
radioproduction
maintenance applications
12 7 N/A N/A N/A
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No x
Mössbauer sources? (specify which & quantity) Yes No x
X ray sources? (specify which & quantity) Yes No x
Intense neutron beam? (specify average En = ?) Yes No x
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11C- Methyoinine and Coline
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
in next future
Yes x No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No x
[11] Type of imaging equipment available on-site Number of
� 511 KeV coincidence
� Gamma camera 2
� Single photon tomography (SPET)
� Positron emission tomography (PET), (PET-CT) 2 (1+1)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No x
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No x
[14] Is the cyclotron used for targetry development? Please, specify. Yes No x
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No x
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
COMMENTS:(e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)
3 He
4 He
191
185

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
186 192
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 1500mCi 95% x 100% Yes x
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 900 mCi daily Yes x No Yes No x
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

20. JAPAN
2005 COUNTRY: JAPAN JAP-1
[1] INSTITUTE: Biomedical Imaging Research Centre
Fukui Medical University
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
OSCAR 5,
superconducting,
negative-ion
RDS eclipse,
23-3 Shimoaizuki, Matsuoka, Yoshida, Fukui, 910-1193
+81 776 61 8430
yfuji@fmsrsa.fukui-med.ac.jp
+81 776 61 8170
Yoshiharu Yonekura
Director, Professor of Medical Imaging
Yasuhisa Fujibayashi, Professor of Molecular Imaging
Tatsuo Ido, Professor of PET Engineering
YEAR OF:
(I) INSTALLATION
MANUFACTURER:
negative-ion
NKK
CMI/CTI
(II) UPGRADE: 2004
MODEL: Oxford
RD/HP
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 12
Yes No
11
Yes No
Maximum beam available (µA) 50 - 40
Typical beam employed (µA) 30 - 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
26 16 2 8 0
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
18
F — 0.5/week
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions? If yes, name of institutions. Yes No
[10] Are clinical& medical research using cyclotron radiopharmaceuticals carried out on-site? Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Number
Single photon tomography (SPET)
Positron emission tomography (PET)
3
–Clinical, Small animal, Plant biochemistry 2
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
1994
193
187

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
188 194
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 18
O (p, n) F
20 18
Ne (d, α) F
16 18
O (α, d) F
37 96 4.2
1.5
18
F RADIOPHARMACEUTICALS PRODUCED
Name Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 10 4/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Acetate 20 1/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 4 1/month
16 13
O(p,α) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
O2
OTHER ISOTOPES PRODUCED
800 Yes
No
Name Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 0.37 2/week
15 15
N(p,n) O
CO 0.37
1/week
15 15
N(p,n) O
CO2 0.37
0.37
1/week
1/week
15 15
N(p,n) O
15 15
N(p,n) O
Name Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu 0.37 1- 2/week Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
64 62 67 18
Cu - ATSM (Hypoxia), Cu - ATSM (Hypoxia), Cu - PTSM (Perfusion) and F - FES (Estrogen receptor)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JAP-2
[1] INSTITUTE: Daiichi Radioisotope Laboratories, Ltd.
453-1 Shimo-okura Matsuo-machi
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Sanbu-gun Chiba 289-1592
+81 479 86 4721
stakashi@drl.co.jp
+81 479 86 5112
Mr. Takashi Syogenji
Manager, RI Production Group
Yasuharu Sato
[3] TYPE OF
Negative ion YEAR OF: (I)
1991
CYCLOTRON:
INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 30
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 30 Yes No
Maximum beam available (µA) 350
Typical beam employed (µA) 300
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
120 120 12
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET) 1
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
195
189

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
190 196
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga 2/week Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
5/week Yes No Yes No
124
I
Yes No Yes No
201
Tl 1/week Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-3
[1] INSTITUTE: Daiichi Radioisotope Laboratories, Ltd.
453-1 Shimo-okura Matsuo-machi
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Sanbu-gun Chiba 289-1592
+81 479 86 4721
stakashi@drl.co.jp
+81 479 86 5112
Mr. Takashi Syogenji
Manager, RI Production Group
Yasuharu Sato
[3] TYPE OF
AVF YEAR OF: (I)
1984
CYCLOTRON:
INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL: MC-40
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 30 Yes No
Maximum beam available (µA) 200
Typical beam employed (µA) 180
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
production
research
maintenance
120 120 12
h/week for
applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET) 1
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
197
191

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
192 198
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl 4/week Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-4
[1] INSTITUTE: Department of Radiology
University of Tokyo
7-3-1 Hongo Bunkyo-ku
Tokyo 113
TELEPHONE NO.:
E-MAIL ADDRESS:
+81 3 381 55411 ext. 5129
FAX NO.:
+81 3 5800 8935
[2] PERSON IN CHARGE:
Toshimitsu Momose, MD
POSITION:
Assistant Professor
OTHER SENIOR STAFF:
NAME/POSITION
Shinya Oku
[3] TYPE OF
Positive ion YEAR OF: (I)
1988
CYCLOTRON:
INSTALLATION
MANUFACTURER: Sumitmo Heavy
Industries, Ltd.
(II) UPGRADE:
MODEL: Cypris 370
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
Typical beam employed (µA)
Yes No
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
production
h/week for
research
h/week for
maintenance
h/week for
applications
10
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) PET clinical
applications
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
199
193

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
194 200
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
DOPA Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
NHSP Yes No Yes No
NHPB Yes No Yes No
Methionine Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammpnia Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
O2
CO2
Water
CO
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-5
[1] INSTITUTE: Gunma University School of Medicine
39-15 Showa-machi 3-chome
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
Maebashi-shi, Gunma-ken 371
+81 27 220 8661
nuclear@med.gunma-u.ac.jp
OTHER SENIOR STAFF:
Professor Keigo Endo
Chairman
Tomio Inoue, M.D.
NAME/POSITION
Kunio Matsubara, PhD.
NAME/POSITION
Katsumi Tomiyoshi, PhD.
[3] TYPE OF
Baby cyclotron YEAR OF: (I)
1983
CYCLOTRON:
INSTALLATION
MANUFACTURER: Japan Steel Works,
Ltd.
(II) UPGRADE:
MODEL: BC 1700
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 10 Yes No
Maximum beam available (µA) 50 50
Typical beam employed (µA) 30 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
16 10 5 0.5 0.5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 0.5 Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 F - α- Methyl - Tryptophan, 11 C – Annexine
[9] Do you supply radionuclides to other If yes and available, name of institution/s & Yes No
institutions?
how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 1
� Gamma camera 2
� Single photon tomography (SPET) 3
� Positron emission tomography (PET)
– Clinical 1
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
201
195

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
196 202
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 4 -5 60 2.0 50 Yes
No
20 Ne (d, α) 18 F 4
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 4 -5 5/week Yes No Yes No
FAMT 4 1/week Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Choline 10 - 15 1/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 10 1/month
16 13
O(p, α) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
O2
Water
21
10
1/week
1/month
15 15
N(p, n) O
15 15
N(p, n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-6
[1] INSTITUTE: HIMEDIC Imaging Center at Lake Yamanaka
562-12 Yanagihara, Hirano
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
[3] TYPE OF
CYCLOTRON:
Yamanakako-mura, Minamitsuru-gun
+81 555 65 9135
himedic@mfi.or.jp
+81 555 20 3007
Dr. Michiru Ide
President
AVF YEAR OF:
INSTALLATION
(I)
(II) UPGRADE:
MANUFACTURER: Sumitomo Heavy
Industries, Ltd.
MODEL: HM 18
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 10 Yes N
Maximum beam available (µA) 70 50
Typical beam employed (µA) 25
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
7 6 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 3
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
1993
203
197

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
198 204
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 29 94 1.3 450 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of
Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 10 5/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of
(list)
batch (GBq) production
Ammonia 3 20/week
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Nuclear reaction used Distribution/
sales
16 13
O(p,α) N Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-7
[1] INSTITUTE: Hokkaido University, Graduate School of Medicine
Department of Tracer Kinetics
Kita 15 Nishi 7
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER: Sumitomo Heavy
Industries, Ltd.
Kita-ku, Sapporo 060-8638
+81 11 706 5150
kuge@med.hokudai.ac.jp
+81 11 706 7155
Nagara Tamaki
Professor and Chairman
Yuji Kuge, Associate Professor
YEAR OF: (I)
INSTALLATION
(II) UPGRADE:
MODEL: CYPRIS-HM 18
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 10 Yes N
Maximum beam available (µA) 50 50
Typical beam employed (µA) 20 15
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20 15 2 3
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11 C - NHSP, 18 F DOPA, 11 C Palmitic Acid , 11 C CGFI 2177
[9] Do you supply radionuclides to other If yes and available, name of institution/s & Yes No
institutions?
how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 2
� Gamma camera
� Single photon tomography (SPET) 5
� Positron emission tomography (PET)
– Clinical 2
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
1998
205
199

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
200 206
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 50 95 1.8 240 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 10 2/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Acetate 8 2/week Yes No Yes No
Methyonine 7 1/week Yes No Yes No
Flumazenil 5 1/week Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 2 Occasionally
16 13
O(p,α) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 1.5 2/week
14 15
N(d,n) O
O2
CO
0.5 2/week
2.0
3/week
14 15
N(d,n) O
14 15
N(d,n) O
CO2
1.0
2/week
14 15
N(d,n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-8
[1] INSTITUTE: Hyogo Institute for Aging Brain and Cognitive Disorders
520 Saisho-ko, Himeji
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Superconducting
negative ion
cyclotron
Hyogo 670
+81 792 95 5511
sasakii@hiabcd.go.jp
+81 792 95 8199
Dr. Masahiro Sasaki
Chief, Nuclear Pharmacology Laboratory
YEAR OF: (I)
INSTALLATION
MANUFACTURER: Oxford (II) UPGRADE:
MODEL: OSCAR-2
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 12 Yes No
Maximum beam available (µA) 100
Typical beam employed (µA) 50
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
production
research
maintenance
6 5 1
3 He
4 He
1992
h/week for
applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11
C MPHA
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
207
201

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
202 208
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 15 50 5 25/ 95% Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 4 2 - 3/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methionine 2 - 3/year Yes No Yes No
NMSP 2 - 3/year Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 5 6 - 10/week
13 15
N(p, n ) O
O2
CO
5
5
2 - 5/month
2 - 5/month
13 15
N(p, n ) O
13 15
N(p, n ) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-9
[1] INSTITUTE: Institute for Biofunctional Research
5-7-1 Fujishiro-dai, Suita-shi
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Osaka 565
+81 6 834 7000
n-ejima@po.iijnet.or.jp
+81 6 872 8761
Dr. Naoto Hashimoto
Director
Norimasa Ejima
[3] TYPE OF
AVF YEAR OF: (I)
1992
CYCLOTRON:
INSTALLATION
MANUFACTURER: Sumitomo Heavy
Industries, Ltd.
(II) UPGRADE:
MODEL: HM 18
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 10 Yes No
Maximum beam available (µA) 25 20
Typical beam employed (µA) 15-20 10-15
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
~24 810 10
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site? Specific to animal PET studies.
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
209
203

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
204 210
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
11
C - N2 40-50 1 per month Yes
Yes
No
No
Yes
Yes
No
No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
13
N –
H2 16 O+5mM
EtOH
1.7 1 per 3 months Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
15
O – N2+O2
(0.4%)
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
7.5 (2-3) × (5-7)
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-10
[1] INSTITUTE: International Medical Centre of Japan
Radiology Department
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
1-21-1 Toyama, Shinjaku-ku
+81 3 3202 7181
ahara@kt.rim.or.jp
+81 3 3202 7181
Toshihiko Hara, MD
Chief - Nuclear Medicine
Noboru Kosaka, MD
[3] TYPE OF
Negative ion YEAR OF: (I)
1994
CYCLOTRON:
INSTALLATION
MANUFACTURER: Japan Steel Works,
Ltd.
(II) UPGRADE:
MODEL: BC 2010N
[4] CYCLOTRON CHARACTERISTICS: p.d.
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 20 1 Yes No
Maximum beam available (µA) 50 30
Typical beam employed (µA) 30 10
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20 10 5 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No 1
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
211
205

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
206 212
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 18.5 70 2 260 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of
Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 7.4 Yes No Yes No
Choline 3.7 Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Choline 14.8 Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 3.7
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-11
[1] INSTITUTE: Japan Atomic Energy Research Institute (JAERI)
1233 Watanuki, Takasaki
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
AVF Cyclotron, K-
CYCLOTRON: 110
MANUFACTURER: Sumitomo Heavy
Industries
MODEL: 930
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Gunma 370-1292
+81 27 346 9420
sekine@taka.jaeri.go.jp
+81 27 346 9688
Dr. Toshiaki Sekine
Deputy Director
Department of Radiation Research for Environment and
Resources
Ms. Noriko Shigeta Ishikoka
Mr. Sutoshi Watanabe
YEAR OF: (I)
INSTALLATION
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 90 50 100 Yes No
Maximum beam available (µA) 5 7 7
Typical beam employed (µA) 5 5 3
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
production
h/week for
research
3 He
h/week for
maintenance
4 He
1990
h/week for
applications
101 15
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 32 Radiography:
Materials science: 28 Proton therapy:
Physics: 12 Neutron therapy:
Activation analysis: Other (specify) 29,cyclotron
technology
development
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
76 Br, 77 Br
[9] Do you supply radionuclides to other If yes and available, name of institution/s & Yes No
institutions?
how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry 2
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
213
207

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
208 214
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 O (α, d) 18 F 0.1
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 0.03 1/month Yes No Yes No
18 F - WATER 0.1 2/week Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Mehionine 0.4 3/week Yes No Yes No
CO2 3 8/week Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
NO - 3 0.3 15/week
16 13
O(p,α) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Products with our cyclotron are used in plant physiology only. Once, we have produced 186 Re for medical research.
Production of this radionuclide, for medical purposes may be done again.
Metallic positron emitters 48 V, 52 Mn, 52 Fe and 62 Zn are also produced.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-12
[1] INSTITUTE: Kanazawa Cardiovascular Hospital
Ha 16 Tanaka, Kanazawa
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
[3]
OTHER SENIOR STAFF:
TYPE OF
Baby cyclotron for
CYCLOTRON: medical use
MANUFACTURER: The Japana Steel
Works Ltd.
MODEL: BC 1710
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Ishikawa
+81 76 253 8000
Toshi@nshnet.or.jp
+81 76 253 0008
Mr. Toshihiko Morikawa
YEAR OF: (I)
INSTALLATION
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 17 10 Yes No
Maximum beam available (µA) 60 60
Typical beam employed (µA)
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
~ 20 ~ 4 ~ 2
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET) 1
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1991
215
209

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
210 216
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
………
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-13
[1] INSTITUTE: Kyoto University Hospital
54 Shogoin Kawahara-cho, Sakyo-ku
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
Kyoto 606-8507
+81-75-751-3306
kawap@kuhp.kyoto-u.ac.jp
+81-75-751-3217
Hidekazu Kawashima, PhD.
Mr. Haruhiro Kitano
[3]
NAME/POSITION
TYPE OF
AVF YEAR OF: (I)
1982
CYCLOTRON:
INSTALLATION
MANUFACTURER: Sumitomo Heavy
(II) UPGRADE: 1997 (change of electronic
Industries
circuit)
MODEL: Cypris 325
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 16 8 Yes No
Maximum beam available (µA) 50 50
Typical beam employed (µA) 25 15
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
8 7 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other:
Radiopharmaceuticals for
clinical and animal studies
7
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[ 11 C]SCH23390, [ 11 C]CFT, [ 18 F]FDOPA
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 2
� Single photon tomography (SPET) 3
� Positron emission tomography (PET)
– Clinical 2
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
217
211

18 F Radionuclide production
Production Typical
production
yield (GBq)
212 218
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 40 97 4 200 Yes
No
20 Ne (d, α) 18 F 17
16 18
O (α, d) F
18
F radiopharmaceuticals produced
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
FDG 16 140/year Yes No Yes No
FLT 2.0 10/year Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C radiopharmaceuticals produced
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Raclopride 2.0 12/year Yes No Yes No
Flumazenil 2.5 4/year Yes No Yes No
PK11195 1.0 6/year Yes No Yes No
Yes No Yes No
13
N radiopharmaceuticals produced
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15
O radiopharmaceuticals produced
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
CO 1.5/min 48/year
14 15
N(d, n ) O
O2
CO2
0.8/min
0.5/min
24/year
24/year
14 15
N(d, n ) O
14 15
N(d, n ) O
Other isotopes produced
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
Comments: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-14
[1] INSTITUTE: Kyushu University
Department of Radiology, Faculty of Medicine
Maidashi 3-1-1, Higashi-ku
Fukuoka 812-8582
TELEPHONE NO.:
E-MAIL ADDRESS:
+81 92 6425 788
FAX NO.:
+81 92 642 5833
[2] PERSON IN CHARGE:
Dr. Yasuo Kuwabara
POSITION:
Chief, Nuclear Medicine Section
OTHER SENIOR STAFF:
Masayuki Sasaki
NAME/POSITION
Isuyoshi Yoshida
NAME/POSITION
Toshimitsu Fukumura
[3] TYPE OF
AVF YEAR OF: (I)
1983
CYCLOTRON:
INSTALLATION
MANUFACTURER: Japan Steel Works,
Ltd.
(II) UPGRADE: 1998
MODEL: BC 1710
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 17 10 Yes No
Maximum beam available (µA) 50 50
Typical beam employed (µA) 30 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
11 7 2 2
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 1
� Single photon tomography (SPET) 3
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
219
213

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
214 220
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 10 95 2 40 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 2/week Yes No Yes No
DOPA Yes No Yes No
Estiradiol Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Raclopride 1/week Yes No Yes No
Methionine 1/week Yes No Yes No
NMPB 1/week Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
H2O
CO
1/week
1/week
14 15
N(d, n ) O
14 15
N(d, n ) O
O2
CO2
1/week
1/week
14 15
N(d, n ) O
14 15
N(d, n ) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-15
[1] INSTITUTE: Medical School of Nagoya University
Department of Radiology
65 Tsurumaicho, Showa-ku
Nagoya City 466
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
+81 52 741 2111 or 733 9415
[2] PERSON IN CHARGE:
POSITION:
Mr. Masanori Tadokoro
OTHER SENIOR STAFF:
Takeo Ishigaki
NAME/POSITION
Masanari Nishino
[3] TYPE OF
Baby cyclotron YEAR OF: (I)
1989
CYCLOTRON:
INSTALLATION
MANUFACTURER: Japan Steel Works,
Ltd.
(II) UPGRADE:
MODEL: BC 2211
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 22 11 Yes No
Maximum beam available (µA) 60 60
Typical beam employed (µA) 100 100
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
10 6 3
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Number
Gamma camera 2
Single photon tomography (SPET) 1
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
221
215

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
216 222
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 16 3 per week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
11
C–Methionine 100 1 per month Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
15
O-Water 100 1 per week
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-16
[1] INSTITUTE: Nagoya City Rehabilitation and Sports Center
1-2 Mikanyama, Yatomi-cho
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
Mizuho-ku, Nagoya 467-8622
+81 52 83 4573
y_ito@mua.biglobe.ne.jp
+81 52 835 3745
Yoshihiro Ito
OTHER SENIOR STAFF:
Noriyuki Kato
NAME/POSITION
Katsumi Araki
AVF YEAR OF: (I)
CYCLOTRON:
INSTALLATION
[3] TYPE OF
MANUFACTURER: Sumitomo Heavy
Industries
(II) UPGRADE:
MODEL: Cypris 370
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 10 Yes No
Maximum beam available (µA) 40 40
Typical beam employed (µA) 20 5 - 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
8 2 3
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11 C Raclopride , Na 18 H
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET) 1
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
1989
223
217

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
218 224
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F 18
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 1.8 1day/week Yes No Yes No
DOPA 1 Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
NMSP 2.5 5 days/year Yes No Yes No
Methionine 2.5 3days/year Yes No Yes No
Palmitic Acid 2.5 6 days/year Yes No Yes No
Acetic Acid 2.5
6 days/year Yes No Yes No
Flumazenil 2.5
1 day/month
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Name
Typical yield on batch Frequency of production Nuclear reaction
(list)
(GBq)
used
Water 4 days/week
14 15
N(d,n ) O
CO, CO2 & O2 1.5 days/week
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-17
[1] INSTITUTE: National Cardiovascular Centre
5-7-1 Fujishirodai, Suita
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER: Sumitomo Heavy
Osaka 565
+81 6 833 5012
ymiyake@hsp.ncvc.go.jp
+81 6 872 7486
Dr. Yoshio Ishida
Director of Nuclear Medicine
Dr. Yoshinori Miyake
AVF
Industries
YEAR OF:
(I) INSTALLATION
(II) UPGRADE:
1989
MODEL: Cypris 370
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 10 Yes No
Maximum beam available (µA) 70 70
Typical beam employed (µA) 20 15
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20 1 2 5 12
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography: 12
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other If yes and available, name of institution/s & Yes No
institutions?
how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
511 KeV coincidence 3
Gamma camera 5
Single photon tomography (SPET)
Positron emission tomography (PET)
5
–Clinical
–Small animal
–Plant biochemistry
2
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
225
219

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
220 226
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 18
O (p, n) F 22 94 0.7 60 Yes
In future
No
20 18
Ne (d, α) F
16 18
O (α, d) F
18.5
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
18
FDG 1.5 1/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
Acetate 3.3 2/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/ Price/
(list)
batch (GBq) production
sales
GBq
Ammonia 1.4 5/week Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction Price/
(list)
used
GBq
Water 3.3 3- 9/week
14 15
N(d, n ) O
CO,CO2,O2 0.01 9/week
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq

2005 COUNTRY: JAPAN JPN-18
[1] INSTITUTE: National Centre of Neurology and Psychiatry
4-1-1 Ogawahigashi-cho
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Superconducting
4-chome, Kodaira, Tokyo 187
+81 423 412 711
matsuda@ncnpmusashi.gr.jp
+81 423 446 745
Dr. Hiroshi Matsuda
Director, Radiological Division
Yutaka Takayama; Satoru Horikoshi
Kenichi Ogawa; Masato Kobayashi
YEAR OF: (I)
1997
CYCLOTRON: compact
INSTALLATION
MANUFACTURER: Oxford (II) UPGRADE:
MODEL: OSCAR, SCC12P
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 12 Yes No
Maximum beam available (µA)
Typical beam employed (µA)
11.4
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
7 10
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Number
Gamma camera 1
Single photon tomography (SPET) 1
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
227
221

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
222 228
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 20 1-2 per week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
15
O-Water 18
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

COUNTRY: JAPAN JPN-19
[1] INSTITUTE: National Institute for Longevity Sciences
Gengo, Morioka
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Negative ion
CYCLOTRON: acceleration AVF
MANUFACTURER: Sumitomo Heavy
Industries
MODEL: HM-18
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Obu 474-8522
+81 562 46 2311
hatanok@nils.go.jp
+81 562 44 6 596
Dr. Kengo Ito
Dr. Kentaro Hatano
Dr. Takashi Kato
YEAR OF: (I)
INSTALLATION
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 18 10 Yes No
Maximum beam available (µA) 50 40
Typical beam employed (µA) 20 25
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
8 4 3 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
18
F, 370MBq
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Number
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
1
–Clinical 1
–Small animal
–Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1995
229
223

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
224 230
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 17 >93 2 80 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 2.4 1/week Yes No Yes No
DOPA 0.875 1/week Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Raclopride 0.37 24/year Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 17.4 30/year
14 15
N(d, n ) O
CO 3.7 5/year
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
11 C - SCH 23390 and B-CFT are used for animal experiments (including PET). Some novel radiopharmaceuticals are
produced for drug development research.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-20
[1] INSTITUTE: National Institute of Radiological Sciences
Advanced Technology Division for Medical Imaging
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
Anagawa 4-9-1, Inage-ku
+81 43 206 3262
kazutosi@nirs.go.jp
+81 43 206 3261
Dr. Kazutoshi Suzuki
Head
Mr. Toshiaki Irie, Head
Mr. Kiyoshi Fukushi, Senior Researcher
Mr. Terushi Haradahira, Senior Researcher
[3] TYPE OF
Negative ion YEAR OF: (I)
2000
CYCLOTRON:
INSTALLATION
MANUFACTURER: Japan Steel Works,
Ltd.
(II) UPGRADE:
MODEL: BC - 2010 BC-2010
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 20 10 Yes No
Maximum beam available (µA) 70 50
Typical beam employed (µA) 20 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
40 36 10 4 26
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No for PET
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Number
Single photon tomography (SPET) 2
Positron emission tomography (PET)
–Clinical
3
–Small animal
–Plant biochemistry
2
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
231
225

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
226 232
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 1 – 10 50 1.5 30 Yes
No
20 Ne (d, α) 18 F 3
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 3 2/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methionine 4 8/week Yes No Yes No
McN5652X 1-2 3/week Yes No Yes No
Raclopride 1-2 1/week Yes No Yes No
MP4A 2 1/week Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 2-3 1/week
16 13
O(p,α) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 2 6/week 14 N(d, n ) 15 O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
11 C - Ro 15-1788, Ro 15- 4513, NMSP and SCH 23390
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-21
[1] INSTITUTE: National Institute of Radiological Sciences
Advanced Technology Division for Medical Imaging
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
Anagawa 4-9-1, Inage-ku
+81 43 206 3262
kazutosi@nirs.go.jp
+81 43 206 3261
Dr. Kazutoshi Suzuki
Head
Mr. Toshiaki Irie, Head
Mr. Kiyoshi Fukushi, Senior Researcher
Mr. Terushi Haradahira, Senior Researcher
[3] TYPE OF
Negative ion YEAR OF: (I)
1994
CYCLOTRON:
INSTALLATION
MANUFACTURER: Sumitomo Heavy
Industries
(II) UPGRADE:
MODEL: HM-18
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 10 Yes No
Maximum beam available (µA) 50 40
Typical beam employed (µA) 20 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
40 34 18 6 16
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No PET
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Number
Single photon tomography (SPET) 2
Positron emission tomography (PET)
–Clinical
3
–Small animal
–Plant biochemistry
2
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
233
227

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
228 234
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 1- 10 20 - 50 1.5 30 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 1 – 10 1 - 2/week Yes No Yes No
Labeled Compd. 1 1/week Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Ro15 - 4513 3 1 - 2/week Yes No Yes No
Methionine 4 6/week Yes No Yes No
WAY 100635 1 -2 2 - 3/week Yes No Yes No
MP4A 1 - 2 1/week Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 2-3 1/week
16 13
O(p,α) N Yes No
NPC 1 1/month Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 2 12/week
14 15
N(d, n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
11 C - NMSP, McN 5652X(+),McN 5652, Ro15 - 1788, SCH 23390, Raclopride, FLB 457, NMPB and Cyanoimipramine

2005 COUNTRY: JAPAN JPN-22
[1] INSTITUTE: National Institute of Radiological Sciences
Advanced Technology Division for Medical Imaging
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
Anagawa 4-9-1, Inage-ku
+81 43 206 3262
kazutosi@nirs.go.jp
+81 43 206 3261
Dr. Kazutoshi Suzuki
Head
Mr. Toshiaki Irie, Head
Mr. Kiyoshi Fukushi, Senior Researcher
Mr. Terushi Haradahira, Senior Researcher
[3] TYPE OF
AVF multi-particle YEAR OF: (I)
1973
CYCLOTRON:
INSTALLATION
MANUFACTURER: Thomson CSF (II) UPGRADE:
MODEL: AVF-930
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 90 55 145 110 Yes No
Maximum beam available (µA) 20 20 10 10
Typical beam employed (µA) 20 15 10 10
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
40 9 6 6 3
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 4 Radiography:
Materials science: Proton therapy: 3
Physics: 16 Neutron therapy:
Activation analysis: Other (specify) 2
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Number
Single photon tomography (SPET) 2
Positron emission tomography (PET)
–Clinical
3
–Small animal
–Plant biochemistry
2
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
235
229

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
230 236
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 1-10 20-50 1.5 30 Yes
No
20 Ne (d, α) 18 F 3
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 1-10 1-2/week Yes No Yes No
Labeled Compd 1 1/week Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
WAY 100635 1-2 1-2/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 2-3 1/week Yes No
NPC 1 1/month Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 2 6/week
14 15
N(d, n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
3 1/month Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
11 C - NMSP, MCN 5652X(+), MCN 5652, RO15-1788, SCH 23390, RACLOPRIDE, FLB457, NMPB,
CYANOIMIPRAMINE, 38K
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-23
[1] INSTITUTE: National Research Institute for Metals
1-2-1 Sengen, Tsukuba
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
Ibaraki 305
+81 298 592 014
NAKAGAWA.Johsei@nims.go.jp
+81 298 592 014
Mr. Johsei Nagakawa
Group Leader
Mr. Norikazu Yamamoto, Subgroup Leader
Mr. Yoshiharu Murase, Researcher
Mr. Toshimitsu Fukuzawa, Researcher
[3] TYPE OF
AVF (fixed energy) YEAR OF: (I)
1986
CYCLOTRON:
INSTALLATION
MANUFACTURER: Japan Steel Works,
Ltd.
(II) UPGRADE:
MODEL: BC 1710
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 17 10 26 20 Yes No
Maximum beam available (µA) 50 50 20 20
Typical beam employed (µA) 30 30 10 10
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
50 40 10
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: 40 Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
Number
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
237
231

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
232 238
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
We use our cyclotron only for studying radiation damage in nuclear reactor materials and not for RADIONUCLIDE
PRODUCTION
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-24
[1] INSTITUTE: Nihon Medi-Physics Co. Ltd. Chiba Facility
3-1 Kitasode, Sodegaura City
Chiba Pref., 299-0266
TELEPHONE NO.:
E-MAIL ADDRESS:
+81 438 634 771
FAX NO.:
+81 438 633 306
[2] PERSON IN CHARGE:
Dr. Masaji Takahashi
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Manager of Technical Section 1
[3] TYPE OF
AVF YEAR OF: (I)
1986
CYCLOTRON:
INSTALLATION
MANUFACTURER: Sumitomo Heavy
Industries
(II) UPGRADE:
MODEL: 750 PV
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 30 Yes No
Maximum beam available (µA) 130/55
Typical beam employed (µA) 120/50
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
130 90 40
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 F
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? — everyday to hospitals.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
239
233

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
234 240
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga 500(@EOB) 3/week Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
81 Rb
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-25
[1] INSTITUTE: Nihon Medi-Physics Co. Ltd. Chiba Facility
3-1 Kitasode, Sodegaura City
Chiba Pref., 299-0266
TELEPHONE NO.:
E-MAIL ADDRESS:
+81 438 634 771
FAX NO.:
+81 438 633 306
[2] PERSON IN CHARGE:
Dr. Masaji Takahashi
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Manager of Technical Section 1
[3] TYPE OF
AVF YEAR OF: (I)
1985
CYCLOTRON:
INSTALLATION
MANUFACTURER: Sumitomo Heavy
Industries, Ltd.
(II) UPGRADE: 1999 (H - acceleration)
MODEL: 480P
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 28 Yes No
Maximum beam available (µA) 55
Typical beam employed (µA) 55
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
120 80 40
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 F
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? — everyday, to hospitals.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals
carried out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
241
235

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
236 242
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
300(@EOS) 5/week Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
81 Rb
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-26
[1] INSTITUTE: Nihon Medi-Physics Co. Ltd., Hyogo Facility
9-1 Techno Park, Sanda City
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Fixed field, fixed
frequency,
accelerating H-ions
Hyogo Pref., 669-1339
+81 795 684 771
+81 795 683 071
Mr. Shigeaki Kataoka
Manager of Technical Section 1
YEAR OF: (I)
INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 30
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 15-30 Yes N
Maximum beam available (µA) 400
Typical beam employed (µA) 360
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
132 120 12
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 F
[9] Do you supply radionuclides to other If yes and available, name of institution/s & Yes No
institutions?
how often? Everyday, to Hospitals
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
Number
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1992
243
237

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
238 244
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In 120(EOB) 1/2week Yes No Yes No
123
I
500(EOS) 2-3/week Yes No Yes No
124
I
Yes No Yes No
201
Tl 400(EOS) 2-3/week Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-27
[1] INSTITUTE: Nihon Medi-Physics Co. Ltd., Hyogo Facility
9-1 Techno Park, Sanda City
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Fixed field, fixed
frequency,
accelerating H-ions
Hyogo Pref., 669-1339
+81 795 684 771
+81 795 683 071
Mr. Shigeaki Kataoka
Manager of Technical Section 1
YEAR OF:
(I) INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 30
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 16-30 Yes No
Maximum beam available (µA) 400
Typical beam employed (µA) 360
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
132 120 12
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 F
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Everyday, to Hospitals
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
Number
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1990
245
239

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
240 246
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In 120(EOB) 1/2week Yes No Yes No
123
I
500(EOS) 2-3/week Yes No Yes No
124
I
Yes No Yes No
201
Tl 400(EOS) 2-3/week Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-28
[1] INSTITUTE: Nikko Memorial Hospital
Shintomi-cho 1-5-13
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Deep valley fixed
CYCLOTRON:
energy proton
Muroran-shi, Hokkaido 51
+81 143 24 1331
+81 143 22 5296
Masahiro Shinohara
Chief of Radiology
Takafumi Mochizuki, Radiology
YEAR OF: (I)
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 111
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
3 He
4 He
1996/7
Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
production
h/week for
research
h/week for
maintenance
h/week for
applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 2
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
247
241

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
242 248
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 11 40% 1.1 100 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 3.7 1 Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-29
[1] INSTITUTE: Nishidai Clinic Diagnostic Imaging Center, Inc.
1-83-8 Takashimadaira, Itabashi-ku
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Tokyo 175-0082
+81 3 5922 0700
tomiyoshi@ncdic.org
+81 3 5922 0701
Kimiichi Uno, M.D.
Chairman
Keiichi Nakagawa, M.D.
Katsumi Tomiyoshi, PhD., M.D.
[3] TYPE OF
Baby cyclotron YEAR OF: (I)
2000
CYCLOTRON:
INSTALLATION
MANUFACTURER: Sumitomo Heavy
Industries, Ltd.
(II) UPGRADE:
MODEL: HM-18
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 10 Yes No
Maximum beam available (µA) 50 50
Typical beam employed (µA) 20 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
11 10 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 F - α - Methyl Tyrosine ( 18 F AMT)
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 5
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
249
243

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
244 250
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 20 95 2.0 100 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 10-15 1-2/day Yes No Yes No
18
F 10 1/week Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
MET 5 1/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 10 3/day
16 13
O(p,α) ) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 5 1/week
13 15
N(p, n) O
CO, O2 & C O2 10 1/week
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced
We carry out clinic diagnostic studies only, in collaboration with Gunma University School of Medicine.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-30
[1] INSTITUTE: Nishijin Hospital
1035 Mizomae-cho, Kamigyo-ku
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
Kyoto 602
+81 75 4615514
cyclo129@mbox.kyoto-inet.or.jp
OTHER SENIOR STAFF:
Dr. Takahiro Kanatsuna
President
Akira Fijii
NAME/POSITION
Hitoshi Horii
NAME/POSITION
Kazuo Wakita
[3] TYPE OF
Positive ion YEAR OF: (I)
1985
CYCLOTRON:
INSTALLATION
MANUFACTURER: Japan Steel Works,
Ltd.
(II) UPGRADE:
MODEL: BC 1710
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 17 10 Yes No
Maximum beam available (µA) 10 ~ 50
Typical beam employed (µA) 70 ~ 80 extracting
efficiency:
(60 ~ 65%)
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
6 ~10 6 ~10 4 ~ 8
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
Number
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
251
245

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
246 252
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-31
[1] INSTITUTE: Nishina Memorial Cyclotron Centre
348-58 Tomegamori, Takizawa
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
Iwate 020-0173
+81 19 688 6071
nmcc@jrias.or.jp
+81-19 688 6072
Tsuneo Takahashi
Director
Shoji Futatsugawa, General Manager
Kouichiro Sera, Professor
Satoru Hatakeyama, Manager
[3] TYPE OF
AVF YEAR OF: (I)
1989
CYCLOTRON:
INSTALLATION
MANUFACTURER: Shimazu (II) UPGRADE:
MODEL: MCY 1750
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 16.9 8.3 Yes No
Maximum beam available (µA)
Typical beam employed (µA)
30 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
40 6 8
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
253
247

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
248 254
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 14.5 1 per week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
Oxygen
Carbon dioxide
Water
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
64 Cu Yes No Yes No
67 Ga Yes No Yes No
86 Y Yes No Yes No
94m Tc Yes No Yes No
103 Pd Yes No Yes No
111 In Yes No Yes No
123
I
124
I
sales
Yes No Yes No
Yes No Yes No
201 Tl Yes No Yes No
211 At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-32
[1] INSTITUTE: Osaka City University Medical School
Division of Nuclear Medicine
1-4-3 Asahi-machi, Abenoku
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Compact
superconducting,
negative ion
Osaka 545-8585
+81 6 6645 3885
ochi@med.osaka-cu.ac.jp
Dr. Hironobu Ochi
Professor, Division of Nuclear Medicine
Dr. Masaji Okamoto
Susumu Shiomi, Associate Professor
YEAR OF: (I)
1992
INSTALLATION
MANUFACTURER: Oxford-NKK (II) UPGRADE: 1993
MODEL: OSCAR SCC12P
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 12 Yes No
Maximum beam available (µA) 50
Typical beam employed (µA) 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
8 2
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
255
249

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
250 256
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 5 50 5 50 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 5 15/month Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methionine 5 2/month Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 2 10/month Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
CO2 2 2/month
O2 4
CO 4
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-33
[1] INSTITUTE: Research Institute for Brain & Blood Vessels Akita
6-10 Senshu-Kubota-machi
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Akita City
+81 188 330 115
kazu@akita.nokenigo.jp
+81 188 332 104
Dr. Kazuhiro Takahashi
Head
Masanobu Ibaraki
[3] TYPE OF
Baby cyclotron YEAR OF: (I)
1983
CYCLOTRON:
INSTALLATION
MANUFACTURER: Japan Steel Works,
Ltd.
(II) UPGRADE:
MODEL: BC-168
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 16 8 Yes No
Maximum beam available (µA) 50 50
Typical beam employed (µA) 30 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
14 2 4
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other If yes and available, name of institution/s & Yes No
institutions?
how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 1
� Single photon tomography (SPET) 1
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
257
251

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
252 258
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 20 60 1.5 40 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 4 1/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methionine 6 2/week Yes No Yes No
3NHPB 2 15/year Yes No Yes No
NMSP 2 15/year Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
H2O 4 20/week
14 15
N(d, n ) O
O2 20 6/week
CO 10 6/week
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-34
[1] INSTITUTE: Tohohu University
Cyclotron and Radioisotope Center (CYRIC)
Aramaki, Aoba-ku
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
Sendai 980-7
+81 217 7798
shino@cyric.tahoku.ac.jp
+81 263 5358
Professor Tsutomu Shinozuka
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
AVF multi particle YEAR OF: (I)
CYCLOTRON:
INSTALLATION
MANUFACTURER: Sumitomo Heavy
(II) UPGRADE:
Industries
MODEL: 680 AVF
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 40 25 65 50 Yes No
Maximum beam available (µA) 15 12 5 5
Typical beam employed (µA)
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
87 ~ 96 16 12
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1977
259
253

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
254 260
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 11 3-4 per week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methionine Yes No Yes No
Doxepin Yes No Yes No
Nemonapride Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water ~ 30 2 per week
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-35
[1] INSTITUTE: Tokyo Metropolitan Institute of Gerontology
35-2 Sakaecho Itabashi
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
NAME/POSITION
Tokyo 173-0015
+81 3 3964 3241 ext. 3505
ishiwata@pet.tmg.or.jp
+81 3 3964 2188
Dr. Kiichi Ishiwata
Head, Positron Medical Center
Dr. Yuichi Kimura, Senior Research Scientist
Dr. Toru Sasaki, Research Scientist
Kenji Ishii, M.D., Research Scientist
Keiichi Oda, Research Scientist
[3] TYPE OF
AVF, positive ion YEAR OF: (I)
1990
CYCLOTRON:
INSTALLATION
MANUFACTURER: Sumitomo Heavy
Industries, Ltd.
(II) UPGRADE:
MODEL: Cypris 370
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 10 24 (not 18 (not Yes No
routinely routinely
Maximum beam available (µA)
used) used)
Typical beam employed (µA) 30 10 ~ 25
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
24 24 8
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
261
255

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
256 262
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
18
F-DOPA Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methionine Yes No Yes No
Flumazenil Yes No Yes No
N-methyl
spiperone
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
Oxygen
used
Carbon dioxide
Carbon
monoxide
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
64 Cu Yes No Yes No
67 Ga Yes No Yes No
86 Y Yes No Yes No
94m Tc Yes No Yes No
103 Pd Yes No Yes No
111 In Yes No Yes No
123
I
124
I
sales
Yes No Yes No
Yes No Yes No
201 Tl Yes No Yes No
211 At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: JAPAN JPN-36
[1] INSTITUTE: University of Tokyo
Department of Radiology
7-3-1 Hongo Bunkyo-ku
Tokyo 113
TELEPHONE NO.:
E-MAIL ADDRESS:
+81 3 3815 5411 ext. 5129
FAX NO.:
+81 3 5800 8678
[2] PERSON IN CHARGE:
POSITION:
Professor Johru Ontoke
OTHER SENIOR STAFF:
Toshimitsu Momose
NAME/POSITION
Shinya Oku
[3] TYPE OF
Positive ion YEAR OF:
1988
CYCLOTRON:
(I) INSTALLATION
MANUFACTURER: Sumitomo Heavy
Industries, Ltd.
(II) UPGRADE:
MODEL: Cypris 370
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
18 10 Yes N
Typical beam employed (µA) 50 50
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
32 32 8
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
511 KeV coincidence 1
Gamma camera 1
Single photon tomography (SPET) 3
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
263
257

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
258 264
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
18
F-DOPA Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methionine Yes No Yes No
N-Methylspiperone
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
Water
Oxygen
C. monoxide
Carbon dioxide
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
64 Cu Yes No Yes No
67 Ga Yes No Yes No
86 Y Yes No Yes No
94m Tc Yes No Yes No
103 Pd Yes No Yes No
111 In Yes No Yes No
123
I
124
I
sales
Yes No Yes No
Yes No Yes No
201 Tl Yes No Yes No
211 At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

21. KAZAKHSTAN
2005 COUNTRY: KAZAKHSTAN KAZ-1
[1] INSTITUTE: Institute of Nuclear Physics
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Variable energy
isochronous
K=50 MeV
MANUFACTURER: Efremov Institute,
Leningrad
MODEL: U 150
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
480082 Almaty-82, Ibragimov str., 1
+7 327 2 546 433
artem@cyclotron.samal.kz
+7 327 2 546 517
Professor A.A. Arzumanov
Head, Accelerator Laboratory
Sychikov Gennadi
Popov Yuri
Batischev Viktor
YEAR OF: (I)
INSTALLATION
1965
(II) UPGRADE: 1972, converted to
variable energy
isochronous
Dual Beams
Beam energies (MeV) 6-30 12-25 18.5-62 25-50 Yes No
Maximum beam available (µA) 500 200 50 100
Typical beam employed (µA) 300 100 20 50
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
40 16.5 15.7 4.3 3.5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: 1.8 Proton therapy:
Physics: 15.7 Neutron therapy:
Activation analysis: Other (specify) Neutron Source, 1.7
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
57
Co, (5)
Mössbauer sources? (specify which & quantity) Yes No
57
Co, (1)
X ray sources? (specify which & quantity) Yes No
57 109
Co, (4) Cd,(6)
[8]
Intense neutron beam? (specify average En = ?) Yes No 2 MeV
Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
201 Tl Chloride, 67 Ga Citzate, 57 Co, 109 Cd, 111 In, 237 Pu, 88 Y, 85 Sr
[9] Do you supply radionuclides to other institutions?If yes and available, name of
institution/s & how often? Hospitals, central clinics, on request.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical, Small animal, Plant biochemistry
Number
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
265
259

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
260 266
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2 (ml)
18 O2 (ml)
18 OH2 (g)
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
18 O2
(l)
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga 13 Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In 3.0 Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl 3.3 On request. Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

22. REPUBLIC OF KOREA
2005 COUNTRY: KOREA, REPUBLIC OF ROK-1
[1] INSTITUTE: Korea Cancer Centre Hospital
Korea Atomic Energy Research Institute
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
215-4 Gongneung-Dong, Nowon-Ku, Seoul
+82 2 970 1331
jschai@kcch.re.kr
+82 2 970 1332
CHAI, Jong-Seo
Principal Researcher/Director
KIM, Yu-Seok, Senior Engineer
HONG, Seong-Seok, Engineer
LEE, Min-Yong, Engineer
[3] TYPE OF
AVF YEAR OF: (I)
1987
CYCLOTRON:
INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL: MC 50
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 50 25 60 50.5 Yes No
Maximum beam available (µA) 100
Typical beam employed (µA) 60 low current low current
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
40 20 6
[6] CYCLOTRON APPLICATIONS: 60 h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 20 123 124 11 45 211 186 124
F production by Ne target; High purity I production by Xe target; on plan: C, Ti, At, Re, I
[9] Do you supply radionuclides to other If yes and available, name of institution/s &
institutions?
how often? 67 Ga-citrate, 201 TICI, Na 123 Yes No
I,
123
I-mIBG – 1 per week
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Number
Gamma camera 6
Single photon tomography (SPET) 1
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
267
261

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
262 268
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α,d ) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: KOREA, REPUBLIC OF ROK-2
[1] INSTITUTE: Korea Cancer Centre Hospital
Korea Atomic Energy Research Institute
215-4 Gongneung-Dong
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
Nowon-Ku, Seoul
+82 2 970 1331
jschai@kcch.re.kr
+82 2 970 1332
CHAI, Jong-Seo
Principal Researcher/Director
KIM, Yu-Seok, Senior Engineer
HONG, Seong-Seok, Engineer
LEE, Min-Yong, Engineer
[3] TYPE OF
Proton only YEAR OF: (I)
2002
CYCLOTRON:
INSTALLATION
MANUFACTURER: IBA (II) UPGRADE:
MODEL: Cyclone-30
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 30 Yes No
Maximum beam available (µA) 350
Typical beam employed (µA) 200
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
45 45
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 6
� Single photon tomography (SPET) 1
� Positron emission tomography (PET) 1
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
269
263

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
264 270
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α,d ) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 7 2/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methionine 1 2/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 1.5 2/week
15 15
N(p, n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: KOREA, REPUBLIC OF ROK-3
[1] INSTITUTE: Korea Cancer Centre Hospital
Korea Atomic Energy Research Institute
215-4 Gongneung-Dong
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
Nowon-Ku, Seoul
+82 2 970 1331
jschai@kcch.re.kr
+82 2 970 1332
CHAI, Jong-Seo
Principal Researcher/Director
KIM, Yu-Seok, Senior Engineer
HONG, Seong-Seok, Engineer
LEE, Min-Yong, Engineer
[3] TYPE OF
Negative ion YEAR OF: (I)
2001
CYCLOTRON:
INSTALLATION
MANUFACTURER: KIRAMS (II) UPGRADE:
MODEL: KIRAMS -13
[4] CYCLOTRON CHARACTERISTICS: H + 13 MeV, 4 sector magnet, 4 th harmonics, PIG internal ion source, GUI
computer control.
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 13 Yes No
Maximum beam available (µA) 60
Typical beam employed (µA) 50
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
24 18 6 4 6
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
F-18, FDG
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? National Cancer Center; Ajou
University Hospital, Yonsei University Hospital.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 2
� Gamma camera 4
� Single photon tomography (SPET) 4
� Positron emission tomography (PET) 2
– Clinical 2
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
271
265

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
266 272
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α,d ) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: KOREA, REPUBLIC OF ROK-4
[1] INSTITUTE: Seoul National University Hospital
Department of Nuclear Medicine
28 Yungun-Dong, Chongro-Ku
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Seoul 110-744
+82 2 760 3805
jmjing@plaza.snu.ac.kr
+82 2 745 7690
Dr. Jae Min Jeong
Director, Cyclotron and Radiochemistry; Associate Professor
In Won Lee, Chief Technologist
[3] TYPE OF
Proton only YEAR OF: (I)
1994
CYCLOTRON:
INSTALLATION
MANUFACTURER: EBCO Technology (II) UPGRADE:
MODEL: TR-13
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 13 Yes No
Maximum beam available (µA) 50
Typical beam employed (µA) 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
44 25 10 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Yunsei University Hospital —
5/week; National Cancer Center — 2/week
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
273
267

18F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
268 274
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 18 97 0.5 200 Yes
No
20 Ne (d, α) 18 F
16 18
O (α,d ) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 7 2/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methionine 1 2/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 1.5 2/week
15 15
N(p, n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: KOREA, REPUBLIC OF ROK-5
[1] INSTITUTE: Samsung Medical Centre
Department of Nuclear Medicine
Sungkyunkwan University School of Medicine
50 Ilwon-Dong, Kangnam-Ku
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Seoul 135-710
+82 2 3410 2623
yschoe@samsung.co.kr
+82 2 3410 2639
Yearn Seong Choe
Assistant Professor/Senior Research Scientist
[3] TYPE OF
Negative ion YEAR OF: (I)
1994
CYCLOTRON:
INSTALLATION
MANUFACTURER: GEMS (II) UPGRADE:
MODEL: PET Trace
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 16.5 8.4 Yes No
Maximum beam available (µA) 75 60
Typical beam employed (µA) 20 25
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
15 6 1 8
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 5
� Single photon tomography (SPET) 5/5
� Positron emission tomography (PET) 1
– Clinical 1/1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
275
269

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
270 276
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 37 97 1.5 ~ 310 Yes
No
20 Ne (d, α) 18 F
16 18
O (α,d ) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 7 -11 6/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
CFT Yes No Yes No
Methionine 1/week Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia > 1.9 1/week
16 13
O (p, α) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water > 3.7 1/week
14 15
N(d, n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: KOREA, REPUBLIC OF ROK-6
[1] INSTITUTE: Asan Medical Center
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
[3] TYPE OF
CYCLOTRON:
Seoul
+82 2 2224 4590
sjoh@amc.seoul.kr
+82 2 2224 4588
Dr. Seung Jun Oh
H - /D - YEAR OF: (I)
INSTALLATION
MANUFACTURER: IBA, s.a., Belgium (II) UPGRADE:
MODEL: Cyclone 18/9
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 18 9 Yes No
Maximum beam available (µA) 50 25
Typical beam employed (µA) 38 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
12 9 3 2
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 12 Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11
C-neuroreceptor imaging radiopharmaceuticals
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Two-three times in a week.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 1
� Gamma camera 5
� Single photon tomography (SPET) 2
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
2001
277
271

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
272 278
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 185 95 2.0 480 Yes
No
20 Ne (d, α) 18 F
16 18
O (α,d ) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 55 2/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Methonine 18.5 3-4/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 18.5 1-2/week 160 (p,a) 13 N Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 18.5 1-2/week 14 n(D,N) 15 O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: KOREA, REPUBLIC OF ROK-7
[1] Institute: Yonsei University Hospital
Department of Nuclear Medicine
134 Sinchon-dong, Seodaemun-gu,
Seoul 120-752
TELEPHONE NO.:
E-MAIL ADDRESS:
+82 2 365 8441
FAX NO.:
+82 2 365 8437
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Wan-won Seo
[3] TYPE OF
1 2
H, H YEAR OF: (I)
2003
CYCLOTRON:
INSTALLATION
MANUFACTURER: IBA (II) UPGRADE:
MODEL: Cyclone 18/9
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 9 Yes No
Maximum beam available (µA)
Typical beam employed (µA)
100 50
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
FDG
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 2
– Clinical 2
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
279
273

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
274 280
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 O (α,d ) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Frequency of
production
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: KOREA, REPUBLIC OF ROK-8
[1] INSTITUTE: NATIONAL CANCER CENTER
Department of Nuclear Medicine
809 Madu1-dong, Ilsan-gu, Goyang-si,
Gyeonggi-do 411-769
TELEPHONE NO.:
E-MAIL ADDRESS:
+82 31 920 0176
FAX NO.:
+82 31 920 0179
[2] PERSON IN CHARGE:
Yong-keun, Kim
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Director
[3] TYPE OF
Proton only YEAR OF: (I)
2001
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI (II) UPGRADE:
MODEL: RDS111
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 50
Typical beam employed (µA) 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
production
h/week for
research
h/week for
maintenance
h/week for
applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
FDG, 11C-acetate, FLT
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 1
� Gamma camera 3
� Single photon tomography (SPET)
� Positron emission tomography (PET) 2
– Clinical 2
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
281
275

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
276 282
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 O (α,d ) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Frequency of
production
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: KOREA, REPUBLIC OF ROK-9
[1] INSTITUTE: The Catholic University of Korea, Kangnam St. Mary's Hospital
Department of Radio-pharmaceutical
505 Banpo-dong, Socho-gu,
Seoul 137-701
TELEPHONE NO.:
E-MAIL ADDRESS:
+82 2 3478 1816
FAX NO.:
+82 2 3478 1819
[2] PERSON IN CHARGE:
Hee-cheol, Kim
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Director
[3] TYPE OF
Proton only YEAR OF: (I)
2004
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI (II) UPGRADE:
MODEL: RDS eclipse
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 60
Typical beam employed (µA) 60
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
12 12 0
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
FDG
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 2
� Single photon tomography (SPET) 2
� Positron emission tomography (PET) 1
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
283
277

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
278 284
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 O (α,d ) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Frequency of
production
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: KOREA, REPUBLIC OF ROK-10
[1] INSTITUTE: Kosin University Gospel Hospital
Department of Cyclotron
34 Ahnnam-Dong,Seo-Ku
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
Pusan 602-702
+82 51 253 1175
Lsk7209@hanmail.net
Sung-kwon Lee
Director,
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Proton only YEAR OF: (I)
2004
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI (II) UPGRADE:
MODEL: RDS eclipse
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 60
Typical beam employed (µA) 60
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
production
h/week for
research
h/week for
maintenance
h/week for
applications
5 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
FDG
[9] Do you supply radionuclides to other institutions?
Yes No
[10]
If yes and available, name of institution/s & how often?
Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
285
279

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
280 286
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 O (α,d ) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Frequency of
production
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: KOREA, REPUBLIC OF ROK-11
[1] INSTITUTE:
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
Kyungbook National University Hospital
50 Samduk-2ga, Jung-gu
Daegu, 700-721
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
YEAR OF: (I)
2005
CYCLOTRON:
INSTALLATION
MANUFACTURER: KIRAMS (II) UPGRADE:
MODEL: KIRAMS-13
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 13 Yes No
Maximum beam available (µA) 60
Typical beam employed (µA) 50
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
production
h/week for
research
h/week for
maintenance
h/week for
applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
287
281

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
282 288
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 O (α,d ) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Frequency of
production
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: KOREA, REPUBLIC OF ROK-12
[1] INSTITUTE: Yeungnam University Medical Center
Department of PET-CT
317-1 Daemyung-Dong, Nam-Ku
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
Daegu 705-717
+82 53 620 3126
stkim@carecamp.com
+82 53 625 3126
Ssang-tae Kim
Director,
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Proton only YEAR OF: (I)
2004
CYCLOTRON:
INSTALLATION
MANUFACTURER: GE (II) UPGRADE:
MODEL: G.E MINItrace
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 9.6 Yes No
Maximum beam available (µA) 35
Typical beam employed (µA) 25
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
7 7 10 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
FDG
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Daegu Catholic University
Hospital -5/week;
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Number
Positron emission tomography (PET) 1
–Clinical
–Small animal
–Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
289
283

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
284 290
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 O (α,d ) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Frequency of
production
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: KOREA, REPUBLIC OF ROK-13
[1] INSTITUTE: Chonnam National Univeristy Hospital
Department of Nuclear Medicine
8 Hak-dong, Dong-gu
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
Gwangju 501-757
+82 61 379 7262
Mozorida78@hanmail.net
+82 61 379 7281
Jeong-young Kim
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Proton only YEAR OF: (I)
2004
CYCLOTRON:
INSTALLATION
MANUFACTURER: GE (II) UPGRADE:
MODEL: G.E PETtrace
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 16.5 Yes No
Maximum beam available (µA) 70
Typical beam employed (µA) 35
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
6 5 1 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
FDG, Ammonia
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
291
285

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
286 292
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 O (α,d ) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Frequency of
production
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: KOREA, REPUBLIC OF ROK-14
[1] INSTITUTE: Eulji Univeristy Hospital
Department of Nuclear Medicine
1306 Dunsan-Dong, Seo-Ku
Daejeon 302-799
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
+82 42 259 1425
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Mon-hyung Gu
[3] TYPE OF
Proton only YEAR OF: (I)
2004
CYCLOTRON:
INSTALLATION
MANUFACTURER: Sumitomo (II) UPGRADE:
MODEL: Cypris HM-12S
12/6MeV
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 12 Yes No
Maximum beam available (µA) 60
Typical beam employed (µA) 60
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
production
h/week for
research
h/week for
maintenance
h/week for
applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
293
287

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
288 294
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 O (α,d ) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Frequency of
production
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: KOREA, REPUBLIC OF ROK-15
[1] INSTITUTE:
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
Chosun University Hospital
588 Seoseok-Dong,Dong-Ku
Gwangju 501-717
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
YEAR OF:
2005 (Installing)
CYCLOTRON:
(I) INSTALLATION
MANUFACTURER: KIRAMS (II) UPGRADE:
MODEL: KIRAMS-13
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) Yes No
Maximum beam available (µA)
Typical beam employed (µA)
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
production
h/week for
research
3 He
h/week for
maintenance
4 He
h/week for
applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
295
289

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
290 296
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 O (α,d ) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Frequency of
production
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GB q
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

23. MEXICO
2005 COUNTRY: MEXICO MEX-1
[1] INSTITUTE: Unidad PET, Facultad de Medicina
Univesidad Nacional Autónoma de México
Circuito Escolar S/N, Ciedad Universitaria
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
NAME/POSITION
Del. Coyoacán 04510 México, D.F.
+52 5623 22 88 or 5623 22 99
pet_unam@hotmail.com
+52 5623 21 15 or 5623 22 41
Dra. Nora E. Kerik Rotenberg
Chief of Department
Dr. René Drucker Colín, Scientific Committee Member
M. en C. Adolfo Zárate Morales, Cyclotron Operator
M. en C. Martha Pedraza López, Radiopharmacist
Q.F.I. Irma Martínez Hernández, Radiopharmacist
Fís. Miguel Angel Avila Rodríguez, Cyclotron Operators
YEAR OF:
2000
[3] TYPE OF
CYCLOTRON:
(I) INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 111
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 50
Typical beam employed (µA) 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
13 8 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18
F - DOPA and Raclopride
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? To hospitals in the future
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical, Small animal, Plant biochemistry 1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
297
291

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
292 298
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 37 95-97 0.8 7 250 Yes
No
20 Ne (d, α) 18 F
16 18
O (α,d ) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 14 1/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
HCN 33.3 1/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 3.7 2/week
16 13
O(p, α) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 28
15 15
N(p,n ) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

24. NETHERLANDS
2005 COUNTRY: NETHERLANDS NET-1
[1] INSTITUTE: Accrec B.V.
Eindhoven University of Technology (TUE)
Cyclotron Building
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Postbus 513, NL-5600 MB Eindhoven
+31 40 247 4048
office.cyclotron@tue.nl
+31 40 243 8060
Professor Dr. M.J.A. de Voight/Professor Dr. M.J. u.d. Wiel
Directors, Accrec B.V.
Negative ion YEAR OF:
Planned during 2002
CYCLOTRON:
(I) INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 30
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
Typical beam employed (µA)
18-30 Yes No
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
299
293

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
294 300
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α,d ) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: NETHERLANDS NET-2
[1] INSTITUTE: Accrec B.V.
Eindhoven University of Technology (TUE)
Cyclotron Building
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
2nd harmonic dees
with 6th harmonic
flat top dees
Postbus 513, NL-5600 MB Eindhoven
+31 40 247 4048
office.cyclotron@tue.nl
+31 40 243 8060
Professor Dr. M.J.A. de Voight/Professor Dr. M.J. u.d. Wiel
Directors, Accrec B.V.
YEAR OF:
(I) INSTALLATION
MANUFACTURER: Home-made (II) UPGRADE:
MODEL: ILEC
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 3 Yes No
Maximum beam available (µA)
Typical beam employed (µA) 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
20 4
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1989
301
295

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
296 302
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α,d ) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: NETHERLANDS NET-3
[1] INSTITUTE: Accrec B.V.
Eindhoven University of Technology (TUE)
Cyclotron Building
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Postbus 513, NL-5600 MB Eindhoven
+31 40 247 4048
office.cyclotron@tue.nl
+31 40 243 8060
AVF YEAR OF: (I)
INSTALLATION
Professor Dr. M.J.A. de Voight/Professor Dr. M.J. u.d. Wiel
Directors, Accrec B.V.
MANUFACTURER: Philips (II) UPGRADE:
MODEL:
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 3- 30 2-20 Yes No
Maximum beam available (µA)
Typical beam employed (µA)
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
~ 80 ~ 4
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Yes Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) Catalysis/
radiochemistry
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 1 (PEP)
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
3 He
4 He
1963
Yes No
Yes No
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
303
297

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
298 304
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α,d ) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
11
C alkanes weekly Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
NO
16 13
O(p, α) N Yes No
Ammonia
16 13
O(p, α) N Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
N2 15 0
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
14 15
N (d, n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Commercial isotope production for Nycomed, Amersham and Cygne
Production of short - lived positron emitters for University Research in catalysis using PEP
Beam analysis techniques for material research (University related)
This AVF Cyclotron will be shut - down in 2002 - 03 and a new Negative ion , IBA, Cyclone 30, 18-30 MeV is planned.

2005 COUNTRY: NETHERLANDS NET-4
[1] INSTITUTE: Groningen University Hospital
PET Centre
P.O. Box 30.001
NL-9700 RB Groningen
TELEPHONE NO.:
E-MAIL ADDRESS:
+31 50 361 3311
FAX NO.:
+31 50 361 1687
[2] PERSON IN CHARGE:
POSITION:
Professor William Vaalburg
OTHER SENIOR STAFF:
A.M.J. Paans
NAME/POSITION
P.H. Elsinga
[3] TYPE OF
AVF YEAR OF:
1991
CYCLOTRON:
(I) INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL: MC 17F
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 17 8.5 Yes No
Maximum beam available (µA) 780 750
Typical beam employed (µA) 20 - 30 20 - 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20 3.5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 2
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
Yes No
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
305
299

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
300 306
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 20 > 94 1 300 Yes
No
20 Ne (d, α) 18 F 7
16 18
O (α,d ) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG > 8 200/year Yes No Yes No
DOPA 0.5 60/year Yes No Yes No
MPPF 0.5 10/year Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Choline > 3 60/year Yes No Yes No
Tyrosine 2-3 40/year Yes No Yes No
Raclopride 0.5 30/year Yes No Yes No
Verapamil 2
20/year
Yes No
Yes No
Bicarbonate > 3
20/year
Yes No
Yes No
Acetate > 3
10/year
Yes No
Yes No
CSP - 12388 1
20/year
Yes No
Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of
(list)
batch (GBq) production
Ammonia 0.8 - 1.0 500/year
15 O RADIOPHARMACEUTICALS PRODUCED
Nuclear reaction used Distribution/
sales
16 13
O (p, n) N Yes No
Yes No
Yes No
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 2-4 600/year
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: NETHERLANDS NET-5
[1] INSTITUTE: Mallinckrodt Medical
P.O. Box 3
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
NL-1755 ZG Pette
+31 224 567 890
frank.de.lange@mkg.com
+31 224 563 566
Eng. (Ir.) H. Buurlage
General Manager
Eng. (Ir.) F. de Lange, Head of Cyclotron Operations
Negative ion YEAR OF:
1992
CYCLOTRON:
(I) INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 30
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 15-30 Yes No
Maximum beam available (µA) 400
Typical beam employed (µA) 2×180
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
130 130 0 10 0
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 0 Radiography: 0
Materials science: 0 Proton therapy: 0
Physics: 0 Neutron therapy: 0
Activation analysis: 0 Other (specify) 0
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
None
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 0
� Gamma camera 0
� Single photon tomography (SPET) 0
� Positron emission tomography (PET) 0
– Clinical 0
– Small animal 0
– Plant biochemistry 0
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
307
301

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
302 308
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α,d ) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga 2/week Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In 1/week Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl 5/week Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: NETHERLANDS NET-6
[1] INSTITUTE: Mallinckrodt Medical
P.O. Box 3
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
NL-1755 ZG Petten
+31 224 567 890
frank.de.lange@mkg.com
+31 224 563 566
Eng. (Ir.) H. Buurlage
General Manager
Eng. (Ir.) F. de Lange, Head of Cyclotron Operations
AVF – Positive ion YEAR OF:
1966
CYCLOTRON:
(I) INSTALLATION
MANUFACTURER: Philips (II) UPGRADE: 1996
MODEL: AVF
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 10-30 Yes N
Maximum beam available (µA) 150
Typical beam employed (µA) 120
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
100 100 0 10 0
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 0 Radiography: 0
Materials science: 0 Proton therapy: 0
Physics: 0 Neutron therapy: 0
Activation analysis: 0 Other (specify) 0
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 0
� Gamma camera 0
� Single photon tomography (SPET) 0
� Positron emission tomography (PET) 0
– Clinical 0
– Small animal 0
– Plant biochemistry 0
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
Yes No
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
309
303

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
304 310
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2 (ml)
18 O2 (ml)
18 OH2 (g)
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α,d ) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
18 O2
(l)
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga 2/week Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In 1/week Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl 5/week Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price
/GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUINRTY NETHERLANDS NET-7
[1] INSTITUTE: Vrije Universiteit, BV Cyclotron VU
De Boelelaan 1081
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
MODEL:
H -
IBA S.A.
Cyclone 18/9
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
NL-1081 HV Amsterdam
+31-20-4449123
info@cyclotron.nl
+31-20-4449128
Dr. P.J. van der Jagt
General Director
Drs. P. Kruijer/Chemist
Dr. ing. F. van Langevelde/Physicist
P.J. van Leuffen/Daily Operations
R. Mooij/Chief Cyclotron Operator
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 18 9 Yes x
Maximum beam available (µA) 80
Typical beam employed (µA) 70
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week for
Hours/week for research Hours/week for Hours/week
radioproduction
maintenance applications
38 35 3
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No x
Mössbauer sources? (specify which & quantity) Yes No x
X ray sources? (specify which & quantity) Yes No x
Intense neutron beam? (specify average En = ?) Yes No x
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
FLT, O-15, Zr-89, I-124
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes x No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes x No
[11] Type of imaging equipment available on-site Number of
� 511 KeV coincidence 1
� Gamma camera 3
� Single photon tomography (SPET) 2
� Positron emission tomography (PET) 2
– Clinical 1
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No x
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No x
[14] Is the cyclotron used for targetry development? Yes x No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes x No
[16] Does your institute accept IAEA research fellows for training/experience? Yes x No
3 He
4 He
1997
311
305

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
306 312
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 95 Yes x
Ne (d, α) 18 F
16 18
O (α, x) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 15 Yes x No Yes x No
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Frequency of
production
Used on site Distribution/
sales
Yes x No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS:(e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)

2005 COUNTRY NETHERLANDS NET- 8
[1] INSTITUTE: Vrije Universiteit
BV Cyclotron VU
De Boelelaan 1081
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
MODEL:
H +
Philips
AVF
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
NL-1081 HV Amsterdam
+31-20-4449123
info@cyclotron.nl
+31-20-4449128
Dr. P.J. van der Jagt
General Director
Drs. P. Kruijer/Chemist
Dr. ing. F. van Langevelde/Physicist
P.J. van Leuffen/Daily Operations
R. Mooij/Chief Cyclotron Operator
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 6-28 3-16 10-45 6-32 Yes No x
Maximum beam available (µA) 200
Typical beam employed (µA) 35 15 10 10
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week for
Hours/week for research Hours/week for Hours/week for
radioproduction
maintenance applications
85 75 10
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No x
Mössbauer sources? (specify which & quantity) Yes No x
X ray sources? (specify which & quantity) Yes No x
Intense neutron beam? (specify average En = ?) Yes No x
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes x No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes x No
[11] Type of imaging equipment available on-site Number of
� 511 KeV coincidence 1
� Gamma camera 3
� Single photon tomography (SPET) 2
� Positron emission tomography (PET) 2
– Clinical 1
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No x
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No x
[14] Is the cyclotron used for targetry development? Yes x No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes x No
[16] Does your institute accept IAEA research fellows for training/experience? Yes x No
3 He
4 He
1965
313
307

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
308 314
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 18
O (p, n) F
Ne (d, α) 18 F
16 18
O (α, x) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 15 Yes No Yes No
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
18 O2 (l)
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No x Yes x No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS:(e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Rb-81 is produced for the production of Rb/Kr-generators

2005 COUNTRY NETHERLANDS NET- 9
[1] INSTITUTE: Kernfysisch Versneller Institute
Zernikelaan 25
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
MODEL:
NL-9747 AA Groningen
+31 50 363 3600
info@kvi.nl
+31 50 363 4003
W K van Asselt
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
[4] CYCLOTRON CHARACTERISTICS:
Compact superconducting cyclotron for research in physics, also used for radiotherapy related radiobiological
experiments, development of dose imaging systems and radiation hardness testing
1996
Ions of alle elements up to lead are accelerated, for more information see http://www.kvi.nl/
1 H
2 H
Dual Beams
Beam energies (MeV) 200 Yes No x
Maximum beam available (µA) 100
Typical beam employed (µA)
[5] CYCLOTRON OPERATION:
Total hours/ year Hours/year
for radionuclide
production
3 He
4 He
Hours/year for research Hours/year for
maintenance
Hours/year for
applications
[6] CYCLOTRON APPLICATIONS: Hours/year Hours/year
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Detector development
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No x
Mössbauer sources? (specify which & quantity) Yes No x
X ray sources? (specify which & quantity) Yes No x
Intense neutron beam? (specify average En = ?) Yes No x
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] Type of imaging equipment available on-site Number of
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes X No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No X
[16] Does your institute accept IAEA research fellows for training/experience? Yes X No
315
309

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
310 316
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS:(e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)

2005 COUNTRY NETHERLANDS NET-10
[1] INSTITUTE: Vrije Universiteit, BV Cyclotron VU
De Boelelaan 1081
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
MODEL:
H -
IBA S.A.
Cyclone 18/9
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
NL-1081 HV Amsterdam
+31-20-4449123
info@cyclotron.nl
+31-20-4449128
Dr. P.J. van der Jagt
General Director
Drs. P. Kruijer/Chemist
Dr. ing. F. van Langevelde/Physicist
P.J. van Leuffen/Daily Operations
R. Mooij/Chief Cyclotron Operator
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 18 9 Yes x No
Maximum beam available (µA) 80
Typical beam employed (µA) 70
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week for
Hours/week for research Hours/week for Hours/week for
radioproduction
maintenance applications
28 25 3
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No x
Mössbauer sources? (specify which & quantity) Yes No x
X ray sources? (specify which & quantity) Yes No x
Intense neutron beam? (specify average En = ?) Yes No x
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
FLT, O-15, Zr-89, I-124
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes x No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes x No
[11] Type of imaging equipment available on-site Number of
� 511 KeV coincidence 1
� Gamma camera 3
� Single photon tomography (SPET) 2
� Positron emission tomography (PET) 2
– Clinical 1
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No x
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No x
[14] Is the cyclotron used for targetry development? Yes x No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes x No
[16] Does your institute accept IAEA research fellows for training/experience? Yes x No
3 He
4 He
2004
317
311

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
312 318
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 95 Yes x
Ne (d, α) 18 F
16 18
O (α, x) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 15 Yes x No Yes x No
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)

25. NORWAY
COUNTRY: NORWAY NOR-1
[1] INSTITUTE: University of Oslo
Department of Physics
P.O. Box 1048, Blindern
N-0316 Oslo
TELEPHONE NO.:
E-MAIL ADDRESS:
+47 22 856 460
FAX NO.:
+47 22 856 422
[2] PERSON IN CHARGE:
POSITION:
Professor Magne Guttormsen
OTHER SENIOR STAFF:
John Rekstad
NAME/POSITION
Svein Messelt
[3] TYPE OF
Sector focusing YEAR OF: (I)
1979
CYCLOTRON:
INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL: MC 35
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 35 17 47 35 Yes No
Maximum beam available (µA) 100 80 10 20
Typical beam employed (µA) 70 50 5 10
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
5 2 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18
F
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
319
313

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
314 320
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α,d ) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

26. PHILIPPINES
2005 COUNTRY: PHILIPPINES PHI-1
[1] INSTITUTE: Positron Emission Tomography and Cyclotron Facility
St. Luke’s Medical Center, E. Rodriguez Avenue
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Quezon City 1102
+63 2 7268369
isaac_nath@yahoo.com /nathgrace@yahoo.com
+63 2 7268369
Jonas Y. Santiago, MD, FACNP
Chief, Section of PET
Nathaniel B. de Vera, Manager, PET & Cyclotron Facility
Katheryn S. Mandap, Radiochemist
Negative Ion YEAR OF:
2001 (November)
(I) INSTALLATION
MANUFACTURER: GE (II) UPGRADE:
MODEL: Minitrace
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 9.5 Yes No x
Maximum beam available (µA) 50
Typical beam employed (µA) 25
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
5 4 0 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: N/A Radiography: N/A
Materials science: N/A Proton therapy: N/A
Physics: N/A Neutron therapy: N/A
Activation analysis: N/A Other (specify) N/A
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No x
Mössbauer sources? (specify which & quantity) Yes No x
X ray sources? (specify which & quantity) Yes No x
Intense neutron beam? (specify average En = ?) Yes No x
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
F-18 and N-13
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No x
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes x No x
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No x
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No x
[14] Is the cyclotron used for targetry development? Yes No x
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No x
[16] Does your institute accept IAEA research fellows for training/experience? Yes x No
3 He
4 He
321
315

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
316 322
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 18
O (p, n) F 18.9 for 60
min
bombardment
97
1.4
16 for 60 min 95
1.4
Ne (d, α) 18 F
16 18
O (α, x) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 5.5 for 30min 1 per day Yes x No Yes No x
9.4 for 60 min
bombardment
11 C RADIOPHARMACEUTICALS PRODUCED
Yes x No Yes No x
Yes No Yes No
Yes No Yes No
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
N/A Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
N-13 1.1 for 30 min occasional
16 13
O(p,a) N Yes No x
ammonia bombardment
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
N/A
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Yes
No x
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu N/A Yes No Yes No
67
Ga N/A Yes No Yes No
86
Y N/A Yes No Yes No
94m
Tc N/A Yes No Yes No
103
Pd N/A Yes No Yes No
111
In N/A Yes No Yes No
123
I
N/A Yes No Yes No
124
I
N/A Yes No Yes No
201
Tl N/A Yes No Yes No
211
At N/A Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
This is the first cyclotron in the country; will be dedicated to produce 18 F FDG and 13 N Ammonia for use in PET
procedures of the Medical Center and supply to other users on request. Detailed information will be supplied when the unit
becomes operational.

27. POLAND
2005 COUNTRY: POLAND POL-1
[1] INSTITUTE: Henryk Niewodnicanczanski Institute of Physics
(HNIP), Radzikowskiego 152
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
PL-31-341 Krakow
+48 12 637 0222
dyrektor@ifj.edu.pl
+48 12 637 5441
Mr. Edmund Makewicz, MSc., EE
Head of Cyclotron Unit
Mr. Henryk Doruch, MSc., EE/Mr. Marek Talach, MSc., EE
Dr. Ryszard Taraszkiewicz, Cyclotron Research
Dr. Barbara Petelenz, head – Laboratory of Physical Chemistry
[3] TYPE OF
AVF isochronous YEAR OF: (I)
1997
CYCLOTRON:
INSTALLATION
MANUFACTURER: HNIP (II) UPGRADE: 2001
MODEL: AIC-144
[4] CYCLOTRON CHARACTERISTICS: K-factor = 60; extraction radius R = 0.62 M.
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 10-60 15-30 30-60 Yes No
Maximum beam available (µA) 100/45
MeV
100 30
Typical beam employed (µA) 2-5 n/a 3-5
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
Variable
production
research
maintenance applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: planned Radiography:
Materials science: Proton therapy: planned
Physics: variable Neutron therapy: planned
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No variable
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No planned
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
111 211
In, At
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
323
317

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
318 324
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
F-Dopa Yes No Yes No
ML01 Yes No Yes No
ML03 Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Choline Yes No Yes No
Deprenyl Yes No Yes No
Methionine Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
Water
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In variable Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At variable Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
57 Co — occasionally, used on site in test of Si strip detectors,
99 Rh — occasionally, used on site for Mössbauer research,
173 Hf — occasionally, used on site in model studies of chemistry of transuranium elements,
178 W, 181 W — occasionally, used on site in model studies of chemistry of transuranium elements.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: POLAND POL-2
[1] INSTITUTE: Warsaw University
Heavy Ion Laboratory
uL Pasteura 5A
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
AVF, 4-sector,
CYCLOTRON: 2-dee, 2 m diameter
MANUFACTURER: Magnet - Dubna,
rest all Polish parts
MODEL:
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
PL-02-097 Warszawa
+48 22 658 2021
+48 22 659 2714
Professor Dr. hab. Jan Kowracki
Mr. Tomasz Czosnyka
Mr. Jerzy Jastrzebski
YEAR OF:
INSTALLATION
(I)
1994
(II) UPGRADE: ECR installation, 1997
Dual Beams
Beam energies (MeV) * Yes No
Maximum beam available (µA)
Typical beam employed (µA)
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
100 24
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
123 111
I, In
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Planned after the ECR installation
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
325
319

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
320 326
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Basic research, e.g. Coulomb excitation, Giant Dipole Resonances
In-beam high-spin spectroscopy
Radioactive decays in He-jet system and isotope separation in-line.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

28. ROMANIA
2005 COUNTRY: ROMANIA ROM-1
[1] INSTITUTE: National Institute for Physics and Nuclear Engineering
IFIN-HH Bucharest, Str. Atomistilor 407
TELEPHONE NO./ FAX NO.:
E-MAIL ADDRESS:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Classical, var.
energy, 60 cm
magnetic pole radius
MANUFACTURER: URSS -
Petrograd/Leningrad
MODEL: U-120/1956
[4] CYCLOTRON CHARACTERISTICS:
1 H
POB MG-6, 76900 Bucharest-Magurele
+40 1 404 23 00/4406/+401 4023 1701
ddudu@ifin.nipne.ro
Dipl. Eng. Dorin Dudu
Head of the Cyclotron Accelerator
Dip. Eng. Nicolae Tetcu, Deputy Head
Dr. Eugen Ivanov
Dr. Petru Mihai Racolta
YEAR OF:
1957/1958
(I) INSTALLATION
2 H
(II) UPGRADE: 1970 development of 7 beam
transport lines
1999 upgrading of RF controls
Dual Beams
Beam energies (MeV) 10-15 10-13 - 20-27 Yes No
Maximum beam available (µA) 25 25 - 10
Typical beam employed (µA) 55 10 - 3
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
45 10 10 10 15
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: - Radiography: -
Materials science: 15 Proton therapy: -
Physics: 5 Neutron therapy: -
Activation analysis: 5 Other (specify) -
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) 22 Na/1 mCi Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) 5 MeV Ø –
10 12 n/cm 2 s typically for d (13 MeV) on Be target.
Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18f, 103 Pd, 22 Na, 67 Ga, 111 In, 123 I, 68 Ge
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
[12]
– Clinical; – Small animal; – Plant biochemistry
Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
327
321

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
322 328
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

29. RUSSIAN FEDERATION
2005 COUNTRY: RUSSIA RUS-1
[1] INSTITUTE: Bakoulev Scientific Centre for Cardiovascular Surgery
Roubevsekoe sh 135
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
Self-shielded, proton
121552 Moscow
+7 095 414 7917
izotop@ntt.ru
+7 095 414 7782
Dr. Evgeny Derevyanko, PhD.
Head of PET Radiochemistry
Professor Leo Bokeria, Director of Bakoulev Cardiosurgery
Dr. Iracly Aslanidis, Head of Nuclear Diagnostics
Dr. Vladimir Leonov, Cyclotron Engineer
YEAR OF: (I)
1998 - mounter
CYCLOTRON: cyclotron
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE: 2001 - accepted
MODEL: RDS 111
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Nil nil Nil Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
6 2 - 4 -
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11 15 11 11 15
C, O, C - acetate, C - methinione, O – water
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence -
� Gamma camera -
� Single photon tomography (SPET) 2
� Positron emission tomography (PET)
– Clinical 1
– Small animal -
– Plant biochemistry -
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
329
323

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
324 330
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 10 70-95 1.1 - 100 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 4 2/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of
(list)
batch (GBq) production
13
N - ammonia 1 1/month
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Water
Nuclear reaction used Distribution/
sales
16
O(p,a) Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: RUSSIA RUS-2
[1] INSTITUTE: Central Research Institute of Roentgenology and Radiology
189646 St. Petersburg
Pesochny-2
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Isochronous
cyclotron with
variable energy
Leningrad ul., 70
+7 812 596 6609
oshtuk@cards.lanck.net or chemcrir@cityline.spb.ru
+7 812 596 6609
Oleg A. Shtukovski, PhD.
Head of the Department of Cyclotron Radiopharmaceuticals
Mikhail Korsakov, Scientific Expert
YEAR OF: (I)
INSTALLATION
MANUFACTURER: Efremov Institute, St.
Petersburg, Russia
(II) UPGRADE:
MODEL: MGC-20P
[4] CYCLOTRON CHARACTERISTICS: H - and D - energy beam 16.4 MeV.
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 4-18 7-10 10-28 4-20 Yes No
Maximum beam available (µA) 100 50 30 25
Typical beam employed (µA) 30 - - -
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
60 40 12 8 -
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
67 111
Ga, In
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 11 different clinical institutions in
St. Petersburg, 2times/week
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 2
� Single photon tomography (SPET) 1
� Positron emission tomography (PET)
– Clinical 2
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
1991
331
325

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
326 332
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 15-18 95+ 1,4 nil 150 Yes
No
20 Ne (d, α) 18 F
16 18
O (α,d ) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 5-10 2/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
11
C – butyrate 4-6 2/week Yes No Yes No
11
C – acetate 2-3 validation for
patient studies
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
13
N – ammonia 3-5 1 runday/week Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
2/week Yes No Yes No
124
I
1/week Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
123 I - iodide, 123 I – iodo hippurate, 123 I – iodo bengal rose, 123 I – iodo iodopentadecanoic acid.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: RUSSIA RUS-3
[1] INSTITUTE: Cyclotron Co. Ltd.
Bondarenko Sq. 1, Obninsk,
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Kaluga Region 249033
+7 95 255 2385
cyclotron@obninsk.com
+7 95 255 2326
Professor N.N. Krasnov
Director General
A.A. Ponomarev, Chief Engineer
Dr. Yuri Sevastianov, Deputy Director General
[3] TYPE OF
lsochronic YEAR OF: (I)
1999
CYCLOTRON:
INSTALLATION
MANUFACTURER: Scientific Institute,
Electrophysics
(II) UPGRADE: 2003
MODEL: RIC - 14
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 14 Yes No
Maximum beam available (µA) 1000
Typical beam employed (µA) 850
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
52 weeks 130 8 20
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
57 Co, 109 Cd , 68 Ge
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
68
Ge
Mössbauer sources? (specify which & quantity) Yes No
57
Co
X ray sources? (specify which & quantity) Yes No
57 109
Co, Cd
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
333
327

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
328 334
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α,d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Upto 30 1/week Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Upto 200 1/week Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: RUSSIA RUS-4
[1] INSTITUTE: Cyclotron Co. Ltd.
Bondarenko Sq. 1, Obninsk,
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Kaluga Region 249033
+7 95 255 2385
cyclotron@obninsk.com
+7 95 255 2326
Professor N.N. Krasnov
Director General
A.A. Ponomarev, Chief Engineer
Dr. Yuri Sevastianov, Deputy Director General
[3] TYPE OF
Classical cyclotron YEAR OF: (I)
1963
CYCLOTRON:
INSTALLATION -
MANUFACTURER: Scientific Institute
Electrophysics
(II) UPGRADE: 1993
MODEL: U - 150 - 1
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 22 22 Yes No
Maximum beam available (µA) 1000 1000
Typical beam employed (µA) 700 700
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
52 weeks in year 2000 144 hours 4 20
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) 57 Co,
109 68
Cd, Ge
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
68
Ge
Mössbauer sources? (specify which & quantity) Yes No
57
Co
X ray sources? (specify which & quantity) Yes No
57 109
Co, Cd
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other If yes and available, name of institution/s & Yes No
institutions?
how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
335
329

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
330 336
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α,d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Up to 30 1/week Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Up to 200 1/week Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: RUSSIA RUS-5
[1] INSTITUTE: Institute of Human Brain RAS
9 Pavlov Street
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
St. Petersburg 197376
+7 812 234 9347
raisa@ihb.spu.ru
+7 812 234 3247
Demianov Alexandr
Cyclotron Engineer
OTHER SENIOR STAFF:
NAME/POSITION
Krasikova Raisa, Head of Radiopharmacy
[3] TYPE OF
Medical YEAR OF: (I)
1990
CYCLOTRON:
INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL: MC-17
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 17 85 Yes No
Maximum beam available (µA) 100
Typical beam employed (µA) 15-40 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
16 7 4 -
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify): PET 16
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
337
331

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
332 338
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 14.8 95 1.0 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 8.8 1/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
L- 11 C – methyl
methionine
4.4 4/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of
(list)
batch (GBq) production
13
N[NH3] 2.6 1/month
15 O RADIOPHARMACEUTICALS PRODUCED
Nuclear reaction used Distribution/
sales
15 13
O(p,a) N Yes No
Yes No
Yes No
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
15
O[H2O] 4.4 25/week
14 15
N(d,n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: RUSSIA RUS-6
[1] INSTITUTE: Kurchatov Institute of Atomic Energy (KIAE)
Moscow 123 182
TELEPHONE NO.:
E-MAIL ADDRESS:
+7 095 196 9782 or +7 095 196 9977*
FAX NO.:
+7 095 737 0600
[2] PERSON IN CHARGE:
POSITION:
Unezhev Vitaly
OTHER SENIOR STAFF:
Oglobin Alexei
NAME/POSITION
V.E. Jarosh
[3] TYPE OF
KIAEC YEAR OF: (I)
1976
CYCLOTRON:
INSTALLATION
MANUFACTURER:
MODEL:
(II) UPGRADE:
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 32 30 70 60 Yes No
Maximum beam available (µA) 30 15 15 20
Typical beam employed (µA) 25 10
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
60 35 4 15 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: 2 Proton therapy:
Physics: 4 Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
[8]
Intense neutron beam? (specify average En = ?) Yes No En=30MeV
Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
339
333

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
334 340
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 98.6 1.5 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of
Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
18
FDG Yes No Yes No
Yes No Yes No On
request
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
37 3 days/week Yes No Yes No On
request
124
I
Yes No Yes No
201
Tl 10 2 days/month Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)

COUNTRY: RUSSIA RUS-7
[1] INSTITUTE: Nuclear Physics Institute at Tomsk Polytechnic University
Lenina 2-1 St., P.O. Box 25
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
634050 Tomsk
+7 3822 417 953 or +7 3822 424 003*
golovkov@npi.tpu.ru
+7 3822 423 934
V.M. Golovkov
Deputy Director
OTHER SENIOR STAFF:
NAME/POSITION
A.I. Komov*, Chief of the Cyclotron Department
[3] TYPE OF
Tomsk(U-120) YEAR OF: (I)
1959
CYCLOTRON:
INSTALLATION
MANUFACTURER: “Electrosila” St.
Petersburg
(II) UPGRADE: 1971
MODEL: R - 7M
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 15 14 30 28 Yes No
Maximum beam available (µA) 35 50 20 55
Typical beam employed (µA) 30 45 50
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
35 19 5 11
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy: 6
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No En=7.5 MeV
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
123
I, Sodium Iodide, Iod - O - gippurate, MIBG, Iodophen
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Institute of Cardiology of Tomsk
Research Centre (TRC) of Siberian Branch of Russian Academy Medical Sciences (SB
RAMS)- 2 per week; Institute of Oncology of TRC SB RAMS- 2 per week; Siberian State
Medical University- 2 per week.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 3
� Single photon tomography (SPET) 1
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
341
335

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
336 342
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Since 1990, TI-199 isotope is produced as analog of TI-201. The “Thallium Chloride, TI-99” radiopharmaceutical is
provided to some medical institutes. Deliverables are realized twice per week. Quantity of the supplying
radiopharmaceutical with the TI-11 is equal to 5-6 Ku/year.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: RUSSIA RUS-8
[1] INSTITUTE: Research Institute of Nuclear Physics
St. Petersburg Technical University
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
194223 St. Petersburg, ul. Kurchatova 10
+812 552 98 96
zabrodin@yandex.ru
+812 552 98 31
V.N. Lomasov
Director, Research Institute of Nuclear Physics (RINP)
B.V. Zabrodin, Director of the Cyclotron Laboratory, RINP
[3] TYPE OF
MGC-20 YEAR OF: (I)
1985
CYCLOTRON:
INSTALLATION
MANUFACTURER:
MODEL:
SRIEPhA, Russia (II) UPGRADE:
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 10 27 20 Yes No
Maximum beam available (µA) 50 50 20 25
Typical beam employed (µA) 20 20 5 15
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
0 – 50 0 - 50 0 – 20 2 – 5 50
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: 0 - 20 Proton therapy:
Physics: 0 - 20 Neutron therapy:
Activation analysis: sometimes Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
67 Ga, 124 I, 85 Sr.
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? As required.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
343
337

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
338 344
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga 1 - 10 As required Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
1 - 10 as required Yes No Yes No
124
I
0,5 - 4 as required Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
85 Sr
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: RUSSIA RUS-9
[1] INSTITUTE: V.G. Khlopin Radium Institute
2nd Murinski Prospect 28
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
149 021 St. Petersburg
+7 812 247
solin@atom.nw.ru
+7 812 237 6181
L.M. Solin, PhD.
Head of Laboratory
YEAR OF: (I)
INSTALLATION
MANUFACTURER: Efremov NIIEFA (II) UPGRADE:
MODEL: MGC-20
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 5-18 3-10 8-24 8-20 Yes No
Maximum beam available (µA) 50 50 20 20
Typical beam employed (µA) 5-15
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
production
research
maintenance
60 48 12
3 He
4 He
1988
h/week for
applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
Sodium iodide, 123 I; Sodium-Iodohippurate, 123 I; 123 I -MIBG; 123 I -BMIPP; 67 Ga Citrate:
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
345
339

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
340 346
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga 3.5 1/ month Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
10 2-3 / week Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

30. SAUDI ARABIA
2005 COUNTRY: SAUDI ARABIA SAU-1
[1] INSTITUTE: King Faisal Specialist Hospital and Research Centre
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Positive ion, AVF,
electrostatic
P.O. Box 3354, Riyadh 11211
+966 1 442 7856
Jamnaz@kfshrc.edu.sa
+966 1 442 4743
Eng. Salman Melibari
Head of, Cyclotron Operations
Eng. Salam Rahma, Senior Engineer
Ahmad Algaith, Engineer
Faisal Alromayanman, Engineer
YEAR OF: (I)
INSTALLATION
MANUFACTURER:
extraction
The Cyclotron
Corporation
(II) UPGRADE:
MODEL: CS 30
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 28.5 15 38 30 Yes No
Maximum beam available (µA) 200 300 135 90
Typical beam employed (µA) 100 100 100 80
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
45 < 10 < 10 < 10
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy: 25 (on hold)
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
[8]
Intense neutron beam? (specify average En = ?) Yes No En =14 MeV
Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11 103 123
C, Pd, and I
[9] Do you supply radionuclides to other institutions?
Yes No
If yes and available, name of institution/s & how often?
124 203
I, Pb
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 5
� Single photon tomography (SPET) 3
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
1981
347
341

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
342 348
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 28 > 95 0.33 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 15 Every day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 3.7 1-2/week Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga 44.0 Every week Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In 16.7 Occasionally Yes No Yes No
123
I
28.0 Every day Yes No Yes No
124
I
16.0 Occasionally Yes No Yes No
201
Tl 34.0 Every Week Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Kr 81m generator production everyday.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

31. SLOVAKIA
2005 COUNTRY: SLOVAKIA SLR-1
[1] INSTITUTE: Slovak Office for Standards, Metrology and Testing
Cyclotron Centre of the Slovak Republic
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Stefanovicova 4, P.O. Box 76, SK-81005 Bratislava
+421 7 524 91085
podhorsky@normoff.gov.sk
+421 7 524 91050
Dr. Dusan Podhorsky
Chairman
Dr. Peter Kovac, Senior Operators
Dr. Josef Kristiak, Senior Scientist
Professor Fedor Macasek, Senior Scientist
Professor Jan Ruzicka, Scientific Secretary
Professor Stefan Saro, Senior Scientist
[3] TYPE OF
Fixed energy H
CYCLOTRON:
- and
D - YEAR OF: (I)
2001 - 2002
ions
INSTALLATION
MANUFACTURER: IBA, s.a., Belgium (II) UPGRADE:
MODEL: Cyclone 18/9
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 9 Yes No
Maximum beam available (µA)
Typical beam employed (µA)
80 35
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: 5 (Planned) Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 11
F – FDG, C – Raclopride
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
349
343

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
344 350
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 2 x 50 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 2 x 20 Yes No Yes No
18
F-DOPA Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Raclopride 40 Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 4
16 13
O(p,α) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
CO2 (10)
14 15
N(p,n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

32. SOUTH AFRICA
2005 COUNTRY: SOUTH AFRICA SAF-1
[1] INSTITUTE: Themba LABS
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Separated sector w/
solid pole injector
cyclotron
P.O. Box 722, Somerset West 7129
+27 21 843 1334
director@tlabs.ac.za or clive@tlabs.ac.za*
+27 21 843 3525
Professor J.F. Sharpey-Schafer until 30 June 2005
Professor K Bharuth-Ram from 1 July 05 to 31 December 06
Dr ZZ Vilakazi, from 1 January 2007 Director
Mr Y Manjoo, Head - Administration
Dr C. Naidoo*, Head - Radionuclide Production
Dr. L. Conradie, Head - Accelerator Group
YEAR OF:
INSTALLATION
(I)
1986
MANUFACTURER: NAC (II) UPGRADE: 1994 (2nd injector)
MODEL:
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 66 - 200 Yes No
Maximum beam available (µA) 180
Typical beam employed (µA) 90
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
144 38 24 24 ~20
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy: 12
Physics: 24 Neutron therapy: 10
Activation analysis: Other (specify)
Radionuclide production
38
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 18 68 82 88
F and F FDG; Ge; Sr, Yr
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Nuclear medicine centres in
South Africa and Namibia — on a weekly basis. 22 Na to USA , European and Far East
Markets, RbCl & Ga irradiated targets to USA (DOE)
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical, Small animal, Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
351
345

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
346 352
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 2 2-4 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch
(list)
(GBq)
18
FDG To be
determined, not
in production
yet
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of Used on site Distribution/ Price/
production
sales
GBq
4 times a week Yes No Yes No Not
availabl
Frequency of
production
Frequency of
production
Yes No Yes No
Yes No Yes No
Yes No Yes No
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga weekly Yes No Yes No $ 372
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
weekly Yes No Yes No $ 405
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
81 Rb/ 81M Kr generators, 123 I – MIBG, 123 I-NaI capsule, , 123 I-NaI solution, 67 Ga-resin

33. SPAIN
2005 COUNTRY: SPAIN SPA-1
[1] INSTITUTE: BARNATRON
Anselm Clave, 100
08950 Espluges de Llobregar
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
Barcelona
+34 93 473 5144
iramirez@cetir.es
+34 93 473 4839
Isabel R. de Arellano
Radiochemist, responsible for Installation
Carlos Piera, responsible for Quality Control
Pedro Larroza, Technician – Production
Martin Vargas, Technician – Quality Control
YEAR OF: (I)
2001
CYCLOTRON:
INSTALLATION
MANUFACTURER: GE (II) UPGRADE:
MODEL: PET Trace
[4] CYCLOTRON CHARACTERISTICS: H - and D - energy beam 16.4 MeV.
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
16.4 MeV Yes No
Typical beam employed (µA) 36
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
11 7 - 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1 Advanced GE
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
353
347

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
348 354
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F >95.5 1.6 mL Yes
No
20 Ne (d, α) 18 F
16 18
O (α,d ) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 65/2 MR bomb 4/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: SPAIN SPA-2
[1] INSTITUTE: Centro Andaluz de Díagnóstíco PET (CADPET)
Ronda de Capuchinos, 11
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
41009 Sevilla
+34 954 432 537 ext. 172
administracíon@cadpet.es/mcantero@cadpet.es/riglesias@cadpe
t.es
+34 954 435 5850
Mr. Miguel Perez
Consejero Delegado (Managing Director)
Mr. Miguel Cantero, Radiochemist
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Mrs. Rocío Iglesias, Radiopharmacist
[3] TYPE OF
YEAR OF: (I)
2001
CYCLOTRON:
INSTALLATION
MANUFACTURER: GE (II) UPGRADE:
MODEL: PET Trace 2132402
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 16.5 Yes No
Maximum beam available (µA) 75
Typical beam employed (µA) 36
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
26 26 n/a
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
Radiopharmaceuticals 26/week
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
CADPET Málaga: 3/week; Hospital Universitario Virgen del Rocío (Sevilla): 5/week
Hospital Universitario Virgen de las Nieves (Granada): 6/week;
IPO (Lisboa): 5/week ;
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
355
349

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
350 356
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 95 1,5 mL Yes
No
20 Ne (d, α) 18 F
16 18
O (α,d ) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 37 17/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: SPAIN SPA-3
[1] INSTITUTE: Centro PET Complutense (CPC)
Manuel Bartolome Cossio, 10
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
Superconducting,
E-28040 Madrid
+34 91 534 4896
radiofarmacia@petmadrid.com
+34 91 553 0845
José Miguel Alfonso
President
Antonio Maldonado, Medical Director
Magdalena Melgarejo Icaza, Laboratory Director
José Manuel Nieto, Administrative Director
YEAR OF: (I)
1994
CYCLOTRON: negative ion
INSTALLATION
MANUFACTURER: Oxford Intr. (II) UPGRADE:
MODEL: OSCAR IV
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 12 Yes No
Maximum beam available (µA) 50
Typical beam employed (µA) 50
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
15 3
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
FDG fabrication
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? IVO (Valencia): 3-4/week;
Hospital del Rocío (Sevilla: 5-9/week; Hospital Dr. Peset (Valencia): 2-3/week
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
Number
–Clinical
–Small animal
–Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
357
351

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
352 358
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 25 >95 5 ± 400 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
18
FDG 25 2-4/day Yes No Yes No P45,000
/injectio
n to
patient
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Centro PET Complutense S.A. is dedicated only in the production and utilization of 1`8 FDG for clinical use. During this
utilization it participates in diverse projects of clinical investigation.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: SPAIN SPA-4
[1] INSTITUTE: Clinica Universitaria de Navarra
Facultad de Medicina
Apartado, 4029
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
NAME/POSITION
31080 Pamplona
+34 948 255 400 ext. 4941
jarichter@unav.es
+34 948 296 500
José A. Richter
MD, PhD.
Chief of Nuclear Medicine
Josep M. Marti-Climent, PhD.
Iván Peñuelas, PhD.
Javier Arbizu, MD
María J. García-Velloso, MD, PhD.
[3] TYPE OF
Double particle YEAR OF: (I)
1996
CYCLOTRON:
INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 18/9
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 9 Yes No
Maximum beam available (µA) 80 35
Typical beam employed (µA) 30 15
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
10
production
research
maintenance applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
359
353

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
354 360
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d,a) 18 F
16 18
O (α, x) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: SPAIN SPA-5
[1] INSTITUTE: MOLYPHARMA
Avenida Dr. Severo Ochoa, 37-41-1
28100 Alcobendas
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
Madrid
+34 91 490 5730
[www.molypharma.es]
+34 91 490 5740
Mr. Rafael Jimenez Shaw
Director de Operaciones
OTHER SENIOR STAFF:
NAME/POSITION
Mr. Tomas Arroyo, Radiopharmacist
[3] TYPE OF
GE Minit-11 YEAR OF: (I)
2001
CYCLOTRON:
INSTALLATION
MANUFACTURER:
MODEL:
(II) UPGRADE:
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 9.6 Yes No
Maximum beam available (µA) 50
Typical beam employed (µA) 35
[5] CYCLOTRON OPERATION: (ESTIMATION)
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20 19 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 5 during 2001 (expected)
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
361
355

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
356 362
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 52 96 0.5 Yes
No
20 Ne (d,α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 37 Daily Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of
(list)
batch (GBq) production
Ammonia 5 Daily
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Nuclear reaction used Distribution/
sales
16 13
O(p, α) N Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

34. SWEDEN
2005 COUNTRY: SWEDEN SWE-1
[1] INSTITUTE: Uppsala Universitet
PET-Centrum
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
UAS, S-75185 Uppsala
+46 18 471 5388
Joachim.Schulz@pet.uu.se
+46 18 471 53890
Joachim Schultz
Engineer
Mr. Gunnar Antonio, Senior Chemist
[3] TYPE OF
Isochron, deflector YEAR OF: (I)
1991
CYCLOTRON:
INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL: MC 17
[4] CYCLOTRON CHARACTERISTICS: 17 MeV protons, 8,5 deuterons, mx 50 µA on target
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 17 17 Yes No
Maximum beam available (µA) 50 50
Typical beam employed (µA) 45 45
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
60 57 0 2 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 3
– Small animal 2
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
363
357

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
358 364
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 37 95 0.9 1.2 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 15 3/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
CO2 ~20 5/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
15
O water 1 5/week
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

35. SWITZERLAND
2005 COUNTRY: SWITZERLAND SWI-1
[1] INSTITUTE: Paul Scherrer Institute
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
CH-5232 Villigen-PSI
+41 56 310 2813
August.Schubiger@psi.ch
+41 56 310 2849
Professor P.A. Schubiger
Head of Centre for Radiopharmacy
Simon Ametamey
Peter Bläuenstein
[3] TYPE OF
PSI construction
Roger Schibli
YEAR OF: (I)
1974
CYCLOTRON:
INSTALLATION
MANUFACTURER:
MODEL:
Philips (II) UPGRADE:
[4] CYCLOTRON CHARACTERISTICS: Total beam is 200 Micro Amp; a splitter divides into main beam and a small part
for the radiopharmacy; this sheet is filled out with respect to RPH applications
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 72 - - - Yes No
Maximum beam available (µA) 70
Typical beam employed (µA) 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
140 150
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
365
359

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
360 366
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 50 >80 2 50 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Dopa Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Flumazenil Yes No Yes No
Raclopride Yes No Yes No
Methionine Yes No Yes No
Ketamine Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Water
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
20 2/month Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
We are concentrating on research of new radiopharmaceuticals for brain imaging and tumour therapy. The products are
investigated in vitro and in vivo (animals). If good results are obtained, first clinical tests are started, but there is no regular
distribution to hospitals anywhere. In addition to 18 F, we are producing 11 C, 67 Cu and 76 Br.

2005 COUNTRY: SWITZERLAND SWI-2
[1] INSTITUTE: Geneva University Hospitals (HUG)
Department of Radiology and Medical Informatics,
Nuclear Medicine Service,
Cyclotron Unit
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Negative ion, fixed
energy
24, rue Micheli-du-Crest, CH-1211 Geneva
+41 22 37 27 580
soloviev.dmitri@hcuge.ch
+41 22 37 27 585
Dr. Dmitri Soloviev, PhD.
Radiopharmacist, Qualified Person, Head of Cyclotron Unit a.i.
Claire Tamburella, PhD., Cyclotron Physicist
YEAR OF:
(I) INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 18/9
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
3 He
4 He
2001
(machine manufactured in
1997)
Dual Beams
Beam energies (MeV) 18 9 Yes No
Maximum beam available (µA) 40 15
Typical beam employed (µA) 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
40 30 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11 C, 18 F, 64 Cu, 55 Co, 86 Y, 124 I
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? [ 18 F]FDG to PET Centers in
Switzerland daily beginning in December, 2005.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 1
� Gamma camera 2
� Single photon tomography (SPET) 2
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
367
361

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
362 368
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 40 95 1.5; 2.5;3 600 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
[ 18 F]FDG 20 daily Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
[ 11 C]acetate 20 3 d/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: SWITZERLAND SWI-3
[1] INSTITUTE: University Hospital Zürich, PET Center
Raemistrasse 100
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
CH-8081 Zürich
+41 1 255 1111
gerrit.westera@dmr.usz.ch
+41 1 255 4428
Professor A. Schubiger
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Dr. G. Westera
[3] TYPE OF
Fixed energy, YEAR OF:
CYCLOTRON: negative ion (I) INSTALLATION
1994
MANUFACTURER: GE (II) UPGRADE:
MODEL: PET Trace
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
Typical beam employed (µA)
16.5 8.5 Yes No
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
40 Stand-by 20 Beam on target 3
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 11
F – DOPA, FLT, C – Various
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Number
Gamma camera 2
Single photon tomography (SPET)
Positron emission tomography (PET)
3
–Clinical 2
–Small animal
–Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
369
363

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
364 370
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 110 95 1.6 600 Yes
No
Ne (d, α) 18 F 600 MBq
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
18
FDG 45 1/day Yes No Yes No SFR
200
18
FET 2.5 1/week Yes No Yes No
18 -
F 1.5 1/week Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
Raclopride 2.5 1/2 weeks Yes No Yes No
Flumarenil 2.5 1/2 weeks Yes No Yes No
Acetate 2.5 1/month Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/ Price/
(list)
batch (GBq) production
sales
GBq
13
NH3 10 10 / week
16 13
O (p, a) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
H2O Continuous 10 / week
15 15
N(p.n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq

36. SYRIAN ARAB REPUBLIC
2005 COUNTRY: SYRIA SYR-1
[1] INSTITUTE: Atomic Energy Commission of Syria (AECS)
P.O. Box 6091
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Damascus
+963 11 391 2896 or 391 3923
+963 11 611 2289
Dr. Abdul Hamid Al-Reyyes
Negative ion,
2001
CYCLOTRON: variable energy
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 30
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 15-30 Yes No
Maximum beam available (µA) 350
Typical beam employed (µA)
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
production
YEAR OF: (I)
INSTALLATION
h/week for
research
h/week for
maintenance
h/week for
applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
123 111 103 11 15
I, In, Pd, C, O
[9] Do you supply radionuclides to other institutions?
Yes No
If yes and available, name of institution/s & how often? Not yet.
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET) 1
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
371
365

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
366 372
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F ~ 90 97 1.3 250 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 30 3/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

37. TURKEY
2005 COUNTRY TURKEY TUR-1
[1] INSTITUTE: MONROL Nuclear Products Inc.
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
MODEL:
(-) Ion Beam
CTI
RDS 111
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Tubitak MAM Teknoparki Gebze / Kocaeli
+90 262 646 40 66
monrol@monrol.com
+90 262 646 40 66
Baris Cakir
Eng. / Specialist
Ozgur Ustaoglu / Asst. Specialist
H. Ozgur Kazanci / Asst. Specialist
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 35
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week for
Hours/week for research Hours/week for Hours/week for
radioproduction
maintenance applications
31 30 - 1 -
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
FLT, FDOPA
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Various National Institutions
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] Type of imaging equipment available on-site Number of
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
2000
373
367

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
368 374
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l) Yes
No
18 18
O (p, n) F
Ne (d, α)
55.5 97 1.2 600
18 F
16 18
O (α, x) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
18
FDG 25 2 Yes No Yes No -
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)

2005 COUNTRY TURKEY TUR-2
[1] INSTITUTE: MONROL Nuclear Products Inc.
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
MODEL:
(-) Ion Beam
IBA
18/9
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Tubitak MAM Teknoparki Gebze / Kocaeli
+90 262 646 40 66
monrol@monrol.com
+90 262 646 40 66
Baris Cakir
Eng. / Specialist
Ozgur Ustaoglu / Asst. Specialist
H. Ozgur Kazanci / Asst. Specialist
Halil Kusanlı / Asst. Specialist
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 18 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 35
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week
for radionuclide
production
3 He
4 He
Hours/week for research Hours/week for
maintenance
2004
-
Hours/week for
applications
31 30 - 1 -
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
FLT
FDOPA
[9] Do you supply radionuclides to other institutions?
Yes No
If yes and available, name of institution/s & how often?
Various National Institutions
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
[11] Type of imaging equipment available on-site Number of
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
375
369

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
370 376
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l) Yes
No
18 18
O (p, n) F
Ne (d, α)
166.5 97 2.1 2000
18 F
16 18
O (α, x) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
18
FDG 74 2 Yes No Yes No -
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS:(e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)

38. UNITED KINGDOM
2005 COUNTRY: UNITED KINGDOM UK-1
[1] INSTITUTE: Douglas Cyclotron Unit
Clatterbridge for Oncology
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
AVF, single particle,
CYCLOTRON:
fixed energy
Bebington, Wirral L63 4JY
+44 151 334 6366
andrzejk@cco.trust.co.uk
+44 151 334 2845
Dr. Andrzej Kacperek
Head, Cyclotron Unit
B. Marsland
YEAR OF: (I)
INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE: 1988 (beamline of proton
therapy)
MODEL: MC-62
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 62 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 20 - 50
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
10 5 2 10
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy: 15
Physics: 2 Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
22
Na
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
64 55
Cu, Co
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Paterson Institute, Christie
Hospital, (4-8/month) Manchester, M20 4BX, U.K.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 1
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1984
377
371

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
372 378
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 18
O (p, n) F
Ne (d, α)
40 95 1 Mostly
recycled
18 F
16 18
O (α, x) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Yes
No
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
1 1/month Yes No Yes No Research
contract
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
We only produce isotopes, not pharmaceuticals.

2005 COUNTRY: UNITED KINGDOM UK-2
[1] INSTITUTE: Hammersmith Imanet Limited
Cyclotron Building
Hammersmith Hospital
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
Ducane Road, London W12 ONN
+44 (0) 208 383 3162
bruce.mackay@csc.mrc.ac.uk
+44 (0) 208 383 2029
Sue Matthews
Managing Director
Bruce Mackay, Cyclotron Operations Manager
Mike Renton, Chief Cyclotron Engineer
Shaun Creasey, Radiochemistry Production Manager
[3] TYPE OF
O-15 generator YEAR OF: (I)
1991
CYCLOTRON:
INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 3D
[4] CYCLOTRON CHARACTERISTICS: Positive ion, fixed energy, fixed frequency, internal beam only.
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 3.8 Yes N
Maximum beam available (µA) 50
Typical beam employed (µA) 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
30 28 2
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) O-15
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 2
– Clinical 2
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
379
373

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
374 380
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
15
H2O
15
CO
continuous
continuous
daily
daily
14 15
N(d,n) O
14 15
N(d,n) O
15
O continuous weekly
14 15
N(d,n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED KINGDOM UK-3
[1] INSTITUTE: Hammersmith Imanet Limited
Cyclotron Building
Hammersmith Hospital
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
Positive ion, variable
Ducane Road, London W12 ONN
+44 (0) 208 383 3162
bruce.mackay@csc.mrc.ac.uk
+44 (0) 208 383 2029
Sue Matthews
Managing Director
Bruce Mackay, Cyclotron Operations Manager
Mike Renton, Chief Cyclotron Engineer
Shaun Creasey, Radiochemistry Production Manager
YEAR OF: (I)
1986
CYCLOTRON: energy
INSTALLATION
MANUFACTURER: Scanditronix (II) UPGRADE:
MODEL: MC 40 Mark II
[4] CYCLOTRON CHARACTERISTICS: Isochronous cyclotron for acceleration of light ions, delivers high quality
external beams via a beam transport system with seven (7) lines to more than 20 installed targets.
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 10-40 5-20 12-53 10-40 Yes No
Maximum beam available (µA) 65 65 50 60
Typical beam employed (µA) 30 30 30 55
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
110 65 40 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Daily
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 2
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
381
375

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
376 382
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 10/F2; 55/F- 95 1.2 150 400 10 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 20 daily Yes No Yes No
Wide range of
compounds
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Extensive range
of compounds
daily Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
15
CO continuous daily
14 15
N(d,n) O
15
CO2
15
H2O
continuous
continuous
daily
daily
14 15
N(d,n) O
14 15
N(d,n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
0.3 Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
81 Rb/Kr generators
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED KINGDOM UK-4
[1] INSTITUTE: Hammersmith Imanet Limited
Cyclotron Building
Hammersmith Hospital
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
Ducane Road, London W12 ONN
+44 (0) 208 383 3162
bruce.mackay@csc.mrc.ac.uk
+44 (0) 208 383 2029
Sue Matthews
Managing Director
Bruce Mackay, Cyclotron Operations Manager
Mike Renton, Chief Cyclotron Engineer
Shaun Creasey, Radiochemistry Production Manager
[3] TYPE OF
GE PETtrace YEAR OF: (I)
2004-2005
CYCLOTRON:
INSTALLATION
MANUFACTURER: GEMS Uppsala. (II) UPGRADE:
MODEL: PETtrace selfshielded
[4] CYCLOTRON CHARACTERISTICS: Positive ion, fixed energy, fixed frequency, internal beam only.
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 16.5 8.4 Yes No
Maximum beam available (µA) 75 60
Typical beam employed (µA) 40 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
60 60 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) O-15
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 2
– Clinical 2
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
383
377

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
378 384
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 18
O (p, n) F 100 95 0.8 Yes
as F-
No
18 18
Ogas (p, n) F
as F2
16 18
O (α, x) F
50
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
11C CO2 Yes No Yes No
11C Methane Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/ Price/
(list)
batch (GBq) production
sales
GBq
Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction Price/
(list)
used
GBq
15
H2O
15
CO
continuous
continuous
daily
daily
14 15
N(d,n) O
14 15
N(d,n) O
15
O continuous weekly
14 15
N(d,n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)

2005 COUNTRY: UNITED KINGDOM UK-5
[1] INSTITUTE: John Mallard Scottish PET Centre
University of Aberdeen
Department of Biomedical Physics and Bioengineering
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Foresterhill, Aberdeen, AB9 2ZD
+44 1 224554767
m.g.dodd@abdn.ac.uk
+44 1 224552514
Dr. Andrew Welch
Director
M.G. Dodd, Cyclotron Engineer
Dr. Lutz Schweiger, Senior Chemist
Negative ion YEAR OF: (I)
1998
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 111
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20 12 4 0.2 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 16 Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify): Target dev. 1
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 1
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
385
379

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
380 386
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 16 40 1.1 180 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 8 daily Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Choline 2 weekly Yes No Yes No
Methylene blue 4 weekly Yes No Yes No
methionone 4 Yes x No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 3 as required
16 ��
O(p, �� � Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 3 weekly
15 15
N(p,n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED KINGDOM UK-6
[1] INSTITUTE: St. Thomas Hospital
The Clinical PET Centre
Guy’s, King’s, St. Thomas School of Medicine
Lambeth Palace Road, London SE1 7EH
TELEPHONE NO.:
E-MAIL ADDRESS:
+44 207 188 4988
FAX NO.:
+44 207 922 0790
[2] PERSON IN CHARGE:
Dr Michael O’Doherty
POSITION:
Director, The Clinical PET Centre
OTHER SENIOR STAFF:
Ms. Margaret Dakin
NAME/POSITION
Mr. Gavin d’Costa
NAME/POSITION
Mr. Phil Halstead
NAME/POSITION
Mr. Paul Marsden
[3] TYPE OF
Negative ion YEAR OF: (I)
1991
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11.5 Yes No
Maximum beam available (µA) 50
Typical beam employed (µA) 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
19 15 4 As required
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
64 18 18
Cu – In development; F – FLT – In development; F –Peptides – In development
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Fluoride for scanner applications
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 2
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
387
381

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
382 388
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F > 95 0.5 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
18
FDG 2 /day Yes No Yes No £ 325/
patient
dose
FLT Yes No Yes No
FMISO Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
11
C Metnionine Yes No Yes No
11
C Fumazenl Yes No Yes No
11
C Methyl
acetate
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
13 NH3
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Water
Frequency of
production
Nuclear reaction used Distribution/
sales
16 13
O(p,��) N Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
15 15
N(p,n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED KINGDOM UK-7
[1] INSTITUTE: University of Cambridge
Wolfson Brain Imaging Centre
Box 65, Addenbrook's Hospital
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
NAME/POSITION
[3] TYPE OF
Negative ion, fixed
CYCLOTRON:
energy
Cambridge CB2 2QQ
+44 1223 33 1820
jcc24@wbic.cam.ac.uk
+44 1223 33 1826
John C. Clark, DSc.
PET Science Director
Professor John D. Pickard, Clinical Director and Chairman
Dr. Franklin I. Aigbirhio, Radiopharmaceutical Chemist
Dr. Peter J. Johnstrom, Radiopharmaceutical Chemist
Mr. Paul Burke, Cyclotron Engineer
YEAR OF:
(I) INSTALLATION
MANUFACTURER: GE (II) UPGRADE:
MODEL: PET Trace
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 16 8.5 Yes No
Maximum beam available (µA) 100 40
Typical beam employed (µA) 45 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
28 6 10 4 8
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify): PET
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 11 64
F peptides; C ligands and substrates; Cu antibody fragments/chelates
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 3/week to two centres.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
511 KeV coincidence 1
Gamma camera 1
Single photon tomography (SPET)
Positron emission tomography (PET)
1
– Clinical 1
– Small animal
– Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1994
389
383

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
384 390
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Water
CO
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
O2
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

39. UNITED STATES OF AMERICA
2005 COUNTRY: UNITED STATES OF AMERICA USA-1
[1] INSTITUTE: Bowman Gray School of Medicine
Medical Centre Boulevard
Winston-Salem, NC 27157
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
+1 910 716 7461
[2] PERSON IN CHARGE:
Dr. Richard L. Witcofski
POSITION:
Director
OTHER SENIOR STAFF:
Richard Ehrenkaufer
NAME/POSITION
Henry Chilton
[3] TYPE OF
Negative ion YEAR OF:
1991
CYCLOTRON:
(I) INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS-112
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
11 Yes No
Typical beam employed (µA) 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
15 15 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 18 F-FDG, daily
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
391
385

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
386 392
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
F – FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
11
C - methionine Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
15
O - water
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-2
[1] INSTITUTE: Brookhaven National Laboratory
Chemistry Department, Bldg. 901
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER: Japan Steel Works,
Upton, NY 11973
+631 344 4587
schlyer@bnl.gov
+631 344 4587
David J. Schlyer
Isochronous YEAR OF:
Ltd.
MODEL: BC 1710
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Manager, BNL Cyclotron Facility
Joanna Fowler, Programme Director
Richard Ferrieri, Chemist
Michael Schueller, Assistant Chemist
1981
(I) INSTALLATION
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 17 10 Yes No
Maximum beam available (µA) 50 50
Typical beam employed (µA) 35 10
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
30 30 0 4 0
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET) 1
� Positron emission tomography (PET) 2
– Clinical
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
393
387

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
388 394
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 13.5 95 3.1 45 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 3.5 daily Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Cocaine 0.5 3/week Yes No Yes No
Raclopride 0.5 3/week Yes No Yes No
Deprenyl 0.5 2/week Yes No Yes No
Clorgyline 0.5 2/week Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 1.0 On demand
16 13
0(p, α) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
195m Pt
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY UNITED STATES OF AMERICA USA-3
[1] INSTITUTE: Brookhaven National Laboratory
Building 901
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
MODEL:
Negative ion
Ebco Technologies
Inc.
TR19
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Upton, NY 11973
(631) 344-4587
schlyer@bnl.gov
(631) 344-7350
David J. Schlyer
Head, BNL Cyclotron Facility
Michael Schueller Assistant Scientist
Richard Ferrieri Chemist
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 19 10 Yes No
Maximum beam available (µA) 100 100 100
Typical beam employed (µA) 30 20
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week
for radionuclide
production
3 He
4 He
Hours/week for research Hours/week for
maintenance
2002
Hours/week for
applications
25 20 5 4
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: 0 Radiography: 0
Materials science: 0 Proton therapy: 0
Physics: 0 Neutron therapy: 0
Activation analysis: 0 Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
New tracers for receptor systems
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] Type of imaging equipment available on-site Number of
511 KeV coincidence 2
Gamma camera 0
Single photon tomography (SPET) 0
Positron emission tomography (PET) 0
–Clinical 2
–Small animal 2
–Plant biochemistry 1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
395
389

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
390 396
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 13.5 95% 2.3 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 13.5 daily Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Cocaine 0.5 3/week Yes No Yes No
Raclopride 0.5 8/week Yes No Yes No
Ritalin 0.5 1/week Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
ammonia 0.25 1/week
16 13
O (p, a) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS:(e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)
[ 11 C] Jasmonic acid for plant studies

2005 COUNTRY: UNITED STATES OF AMERICA USA-4
[1] INSTITUTE: Carolinas Medical Center
Department of NM & PET
1000 Blyth Blvd., P.O. Box 32861
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Charlotten NC 28232
+1 704 355 2276
Zedd@worldnet.att.net
Dr. Ron Borchert
YEAR OF: (I)
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 11.5 Yes N
Maximum beam available (µA) 80
Typical beam employed (µA) 20-40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
production
h/week for
research
3 He
h/week for
maintenance
4 He
1993
h/week for
applications
80 80
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Confidential
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 6
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
397
391

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
392 398
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F ~ 37 95 0.5 500 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 400-450 2-4/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of
(list)
batch (GBq) production
Ammonia 15 - 22 1-2/week
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Nuclear reaction used Distribution/
sales
16 13
O(p, α) N Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-5
[1] INSTITUTE: Case Western Reserve University
and University Hospitals of Cleveland
Division of Radiology
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
11100 Euclid Avenue, Cleveland, OH 44139
+1 216 844 7350
msb5@po.cwru.edu
Dr. Marc Berridge
Associate Professor
Lei Zheng
Ken Voelker
YEAR OF: (I)
1985
CYCLOTRON:
INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL: MC-17
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
17 8 Yes No
Typical beam employed (µA) 30 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
25 25 average: 6 (some
weeks, none)
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 18 F-Fluoride; 13 N-Ammonia; 18 F-
FDG
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 1
� Gamma camera 2
� Single photon tomography (SPET) 3
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
399
393

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
394 400
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-6
[1] INSTITUTE: Childrens Hospital of Michigan
PET Center
3901 Beaubien Boulevard
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Detroi, MI 48201
+1 313 993 2618
tmangner@PET.wayne.edu
+1 313 993 3845
Dr. Thomas J. Mangner
Director, PET Chemistry
Dr. Harry T. Chugani, Medical Director
[3] TYPE OF
Negative ion YEAR OF: (I)
1993
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 100
Typical beam employed (µA) 20 - 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
40 20-24 10 4
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 20 - 24 Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11 11
C – leucine; C - DWAY
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
401
395

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
396 402
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 22 >95 0.35 150 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 12 5-6/week Yes No Yes No
18
F FLT 2 1/week Yes No Yes No
18
F FMAU 1.5 1/monoth Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
11
C FMZ 15 2-3/week Yes No Yes No
11
C AMT 6 2-3/week Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
13
N NH3 2 5-10/week 16 13
O(p, α) N Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
15
O Water 4 5-6/month
15 15
N(p,n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Other radiopharmaceuticals produced on an irregular basis: C-11 acetate, C-11 m-hydroxyephedrine (HED), 2-C-11
thymidine, C-11 methionine, F-18 FAU, F-18 FIAU, F-18 FBAU.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY UNITED STATES OF AMERICA. USA-7
[1] INSTITUTE: Columbia University, Kreitchman PET Center
177 Ft Washington Ave, MHB B1 room 4
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
Negative Ion
Medical Cyclotron
CTI
New York, NY 10032
(212)923-1555
nrs17@columbia.ed
(212)543-8879
Ronald Van Heertum M.D
Director Kreitchman PET Center
Norman Simpson, Director Radioisotope & Radioligand
Product
Dave Wilson, Radiopharmacy Manager
YEAR OF:
(I) INSTALLATION:
MODEL:
RDS112
(II) UPGRADE:
n/a
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11MeV N/A N/A N/A Yes No
Maximum beam available (µA) 120 µA
(spilt
beam)
N/A N/A N/A N/A
Typical beam employed (µA) 30-40 N/A N/A N/A N/A
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week for Hours/week for research Hours/week for Hours/week for
radioproduction
maintenance applications
75
18
F – 15
0 cyclotron research 20
15
O – 0.5
13
N – 0.25
11
C -15
2 hours chem. Res
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: 40 Radiography: 0
Materials science: 0 Proton therapy: 0
Physics: 0 Neutron therapy: 0
Activation analysis: 0 Other (specify) 0
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] Type of imaging equipment available on-site Number of
� 511 KeV coincidence 3
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical, Small animal, Plant biochemistry 3
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
1992
403
397

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
398 404
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 81.4 98% 1.2ml 624 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
18
FDG 40.7 2 Batches/Day Yes No Yes No
FPS 3.7 1/month Yes No Yes No
Fallypride 3.7 2/month Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
M100907 7.4 2 Batches/week Yes No Yes No
Raclopride 7.4 4 Batches/week Yes No Yes No
WAY 100635 0.37 2 Batches/week Yes No Yes No
DASB .74 2 Batches/week Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/ Price/
(list)
batch (GBq) production
sales
GBq
Ammonia 1.85 2-3 per week 16 13
0(p,α) N Yes No N/A
Yes No N/A
Yes No N/A
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction Price/
(list)
used
GBq
Oxygen 3.7 1 Batch every 2-3 months
15 15
N(p,n) O N/A
Water 3.7 2-3 Batches per month
15 15
N(p,n) O N/A
Carbon
Monoxide
N/A
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu N/A N/A Yes No Yes No
67
Ga N/A N/A Yes No Yes No
86
Y N/A N/A Yes No Yes No
94m
Tc N/A N/A Yes No Yes No
103
Pd N/A N/A Yes No Yes No
111
In N/A N/A Yes No Yes No
123
I
N/A N/A Yes No Yes No
124
I
N/A N/A Yes No Yes No
201
Tl N/A N/A Yes No Yes No
211
At N/A N/A Yes No Yes No
[17] COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)
[C-11]NNC112, [C-11]acetate, [C-11]Palmitate, [C-11]mHED, [C-11]cocaine, [C-11]Carfentil, [C-11]DTBZ,
[C-11]McN5652

2005 COUNTRY: UNITED STATES OF AMERICA USA-8
[1] INSTITUTE: Creighton University
Center for Metabolic Imaging
901 Dorcas Street
Omaha, NE 88106
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
+1 402 346 4181
[2] PERSON IN CHARGE:
Dr. Marc Wrichelt
POSITION:
Manager
OTHER SENIOR STAFF:
Dr. Mike Harrington
NAME/POSITION
Mr. Steve Torres
[3] TYPE OF
Negative ion YEAR OF: (I)
1989
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
11 Yes No
Typical beam employed (µA) 20-40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
~ 7 2
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other If yes and available, name of institution/s &
institutions?
how often? 18 Yes No
F-FDG
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
405
399

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
400 406
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-9
[1] INSTITUTE: Crocker Nuclear Laboratory
University of California, Davis, 1 Bainer Drive
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER: W.M. Brobeck &
Davis, CA 95616
+1 916 752 1460
Solar@Crocker.UCDavis.edu
+1 916 752 0952
Dr. Manuel C. Lagunas-Solar
Senior Radiochemist
Mr. Nolan X. Zeng
Mr. Carlos M. Castaneda
Ms. Krystyna Trzepla-Nabaglo
76 inch isochronous
Associates
YEAR OF:
(I) INSTALLATION
(II) UPGRADE:
1964-1966
[4]
MODEL:
CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
4-68 15-45 20-90 16-90 Yes No
Typical beam employed (µA) 30 40 1 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
112 4-8 ~ 16
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) Food irradiation
& conservation
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 205 206 67
F; Bi; Bi; Cu
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Benedict Nuclear Pharmaceuticals,
CO. USA – 4/w; University of California, Irvine, CA, USA – 1-2/w; University of California,
Berkley, CA, USA –1-2/w; VA Hospital, Palo Alto CA. USA – 1-2/w; National Institute of
Health, MD, USA – 2-4/y; NeoRx Corporation, WA, USA – 2-4/y
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried out
on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
– Clinical; – Small animal; – Plant biochemistry
Number
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
407
401

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
402 408
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
3.7 – 7.4 4/week Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
205 Bi, 206 Bi
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-10
[1] INSTITUTE: Downstate Clinical PET Center
Methodist Medical Center
221 North East Glen Oak Ave.
Illinois 61606
TELEPHONE NO.:
E-MAIL ADDRESS:
+1 309 6724 191
FAX NO.:
+1 309 6712 166
[2] PERSON IN CHARGE:
Dr. Danny Bingham
POSITION:
Manager
OTHER SENIOR STAFF:
NAME/POSITION
Brenda Shields
[3] TYPE OF
Negative ion YEAR OF: (I)
1990
CYCLOTRON:
INSTALLATION
MANUFACTURER:
MODEL:
CTI, Inc. (II) UPGRADE:
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
11 Yes No
Typical beam employed (µA) 20-40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20 20 0.5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 18 F-FDG, 5/week
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 1
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
409
403

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
404 410
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-11
[1] INSTITUTE: Duke University Medical Centre
Department of Radiology
Box 3808
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Isochronous fixed
CYCLOTRON: field, positive ion
MANUFACTURER: The Cyclotron
Corporation
MODEL: CS-30
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Durham, NC 27710
+1 919 684 7708
zalut001@mc.duke.edu
+1 919 684 7121
Dr. Bruce Wieland
Director, Cyclotron
Dr. Michael Zalutsky, Professor
YEAR OF: (I)
INSTALLATION
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 27.6 14 28.3 Yes No
Maximum beam available (µA) 120 120 100
Typical beam employed (µA) 70 70 50
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
32 28 4 8
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 1
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1985
411
405

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
406 412
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 40 97 0.4 300 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 12 3/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
ammonia 1 3/week 13 C(p,n) 13 N Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
H2O
O2
CO
1
8
8
2/week
2/week
2/week
14 15
N(d,n) O
14 15
N(d,n) O
14 15
N(d,n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
0.1 4/week Yes No Yes No
201
Tl Yes No Yes No
211
At 4 1/week Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-12
[1] INSTITUTE: Emory University, Division of Nuclear Medicine
1364 Clifton Road NE
Atlanta, GA 30322
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
+1 404 712 7930
[2] PERSON IN CHARGE:
POSITION:
Mark Goodman
OTHER SENIOR STAFF:
NAME/POSITION
Ronald Crowe
[3] TYPE OF
Negative ion YEAR OF: (I)
1992
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
11 Yes No
Typical beam employed (µA) 20-40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
30 ~ 4
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 2
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
413
407

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
408 414
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-13
[1] INSTITUTE: Gershenson Radiation Oncology Center
Harper University Hospital and Wayne State University
3990 John R
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
50 MeV deuteron
superconducting
Detroit, MI 48201
+1 313 745 2487
maughanr@kci.wayne.edu
+1 313 745 2314
Dr. Richard L. Maughan
Mark Yudelev, PhD., Senior Clinical Medical Physicist
YEAR OF:
(I) INSTALLATION
MANUFACTURER:
cyclotron
Michigan State
University
(II) UPGRADE:
MODEL: K100-Harper
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 48.5 Yes No
Maximum beam available (µA) ~ 20
Typical beam employed (µA) ~ 12
[5] CYCLOTRON OPERATION:
Totalhours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
71 6 15 50
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 1 Radiography:
Materials science: Proton therapy:
Physics: (medical) 5 Neutron therapy: 50
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No En = 19MeV, 55
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
None
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
1990
415
409

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
410 416
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-14
[1] INSTITUTE: Good Samaritan Medical Center
PET Net Pharmaceutical Services
1111 E. McDowell Road, West Tower, Lower Level 1
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
NAME/POSITION
+1 602 239 4100/4747
+1 602 239 2810
Dr. Tricia Giurlani
PDC Manager
Dr. Michael Lawson
Mr. David Stith
Mr. Jay Stivers
[3] TYPE OF
Negative ion YEAR OF: (I)
1990
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 40-100
Typical beam employed (µA) 20-100
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
15-30 5-10 5-10
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 18 F-FDG, daily; 13 N-ammonia,
1/month.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
417
411

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
412 418
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-15
[1] INSTITUTE: Indiana University Cyclotron Facility
2401 Milo B. Sampson Lane
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
Bloomington, IN 47408
+1 812 8559 365
@iucf.indiana.edu
+1 812 8556 645
Dr. John M. Cameron
Director
D. Friesel
J. Collins
[3] TYPE OF
Separated sector
G. East
YEAR OF: (I)
1975
CYCLOTRON:
INSTALLATION
MANUFACTURER: In-house (II) UPGRADE:
MODEL: K200
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 205 Yes N
Maximum beam available (µA) 5
Typical beam employed (µA) 5
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
125 10 20 95
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 5 Radiography:
Materials science: 50 Proton therapy: 90
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
None
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
419
413

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
414 420
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-16
[1] INSTITUTE: Indiana University Cyclotron Facility
2401 Milo B. Sampson Lane
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
Bloomington, IN 47408
+1 812 8559 365
@iucf.indiana.edu
+1 812 8556 645
Dr. John M. Cameron
Director
D. Friesel
J. Collins
G. East
Separated sector YEAR OF:
1972
CYCLOTRON:
(I) INSTALLATION
MANUFACTURER: In-house (II) UPGRADE:
MODEL: K16
[4] CYCLOTRON CHARACTERISTICS: (Used as injector to K2000).
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 16 Yes No
Maximum beam available (µA) 20
Typical beam employed (µA) 5
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
125 10 20 95
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 5 Radiography:
Materials science: 50 Proton therapy: 90
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
421
415

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
416 422
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-17
[1] INSTITUTE: John Hopkins University School of Medicine
Division of Nuclear Medicine, PET Center
600 North Wolfe Street, Nelson B1-150
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
Baltimore, MD 21287
+1 410 955 2916
rfd @jhu.edu
+1 410 955 0691
Robert F. Dannais, PhD.
Professor, Radiology/Director, PET Center
Hayden T. Ravert, PhD.
John L. Musachio, PhD.
William B. Mathews, PhD.
[3] TYPE OF
Negative ion YEAR OF: (I)
2000
CYCLOTRON:
INSTALLATION
MANUFACTURER: GE (II) UPGRADE: The installation of the
PETtrace
MODEL: PET Trace represents an upgrace from our previous Scandinotrix MC-16F
which is still on-site, but no longer used.
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 9 Yes No
Maximum beam available (µA) 75 40
Typical beam employed (µA) 60 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
40 39 20 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify): Radiotracer
chemistry
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 2
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
423
417

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
418 424
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F ~ 90 > 90 1.5 800 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG > 55 2/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Many 11 C
ligands
~ 3.7 4/daily Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water On-line, ~ 3 GBq daily
14 15
N(d,n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-18
[1] INSTITUTE: Kettering Memorial Hospital
Department of Nuclear Medicine and PET
3535 Southern Boulevard
Kettering, OH 45429
TELEPHONE NO.:
E-MAIL ADDRESS:
+1 937 296 7211
FAX NO.:
+1 937 296 4265
[2] PERSON IN CHARGE:
POSITION:
Dr. Joseph Mantil
OTHER SENIOR STAFF:
NAME/POSITION
Dr. Martin Satter
[3] TYPE OF
Negative ion YEAR OF: (I)
1989
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 25-43
Typical beam employed (µA) 20-35
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
12 12 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
425
419

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
420 426
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-19
[1] INSTITUTE: LA Tech Center
UCLA School of Medicine
Department of Molecular and Medical Pharmacology and
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PETNet Pharmaceuticals, Inc.
+1 310 670 1010
hpadgett@mednet.ucla.edu
+1 310 670 2521
[2] PERSON IN CHARGE:
Henry C. Padgett, PhD.
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Managing Director
[3] TYPE OF
Deep Valley YEAR OF: (I)
2000
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS-111 (2)
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 60
Typical beam employed (µA) 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20-30 20-30
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
124
I
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
427
421

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
422 428
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 95+ ~ 1 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 5 days/week Yes No Yes No
F-dopa (in progress) Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
[ 11 C] CO2 Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-20
[1] INSTITUTE: Lawrence Berkeley Laboratory
Department of Functional Imaging
1 Cyclotron Road, 55-121
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
Berkeley, CA 94720
+1 510 486 5276
JPONEIL@LBL.gov
+1 510 486 6208
James P. O’Neil
Supervisor, Biomedical Isotope Facility
Dr. Thomas F. Budinger
Dr. Henry VanBrocklin
[3] TYPE OF
Negative ion YEAR OF: (I)
1994
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 111
[4] CYCLOTRON CHARACTERISTICS: Prototype(1 st built), H + only, dual beam, 1 fixed 112–style target, 1 8 position
turret assembly
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 50
Typical beam employed (µA) 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics:

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
424 430
% Isotopic
enrichment
18 O used
18 18
O (p, n) F 9
33
20 18
Ne (d, α) F
16 18
O (α, d) F
37
> 95
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
0.3
1
10 Yes
No
Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Various 1/week Yes No Yes No
18
FMT 1.9 - 3.7 24/week Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Choline Various 1 week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 1.1 3/month
16 13
O(p, α) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-21
[1] INSTITUTE: Mallinckrodt Institute of Radiology
Washington University
510 Kingshighway
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Cyclone 30; 4 beam
CYCLOTRON:
lines
MANUFACTURER: IBA, s.a., The
Cyclotron Corp., and
Japan Steel Works
MODEL: CS-15 (3); JSW 168
(1)
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
St. Louis, MO
+1 314 362 8435
Professor M.J. Welch
Division Head of Radiological Sciences
YEAR OF:
(I) INSTALLATION
(II) UPGRADE:
3 He
4 He
1977 and 1991
Dual Beams
Beam energies (MeV) 16 8 Yes No
Maximum beam available (µA) 80 80
Typical beam employed (µA) 40-50 30-40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
production
h/week for
research
h/week for
maintenance
h/week for
applications
35 35
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify): PET 35
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 5
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
431
425

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
426 432
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 18
O (p, n) F
20 18
Ne (d, α) F
16 18
O (α, d) F
37-111 95 1.7
1.2
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 29-60 daily Yes No Yes No
Captopi1 Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Acetate 10 3/week Yes No Yes No
Palmitate 8 3/week Yes No Yes No
Glucose 1.5 3/week Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 4
16 13
O(p, α) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 4-8 Varies
14 15
N(d,n) O
Oxygen 4-8 Varies
14 15
N(d,n) O
CO 4-8 Varies
14 15
N(d,n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu 15 2/week Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
76 Br, 66 Ga
Yes
No
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-22
[1] INSTITUTE: Massachusetts General Hospital
Department of Radiology
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
NAME/POSITION
Boston, MA 02114
+1 617 726 8336
correia@PET.mgh.harvard.edu
+1 617 726 5123
John A. Correia, PhD.
Director, Cyclotron Laboratory
Eli Livni, PhD., Radiochemist
David Elmaleh, PhD., Radiochemist
Alan Fischman, MD, PhD., Physician
William Bucekwicz, Cyclotron Engineer
[3] TYPE OF
AVF YEAR OF: (I)
1989
CYCLOTRON:
INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL: MC-17
[4] CYCLOTRON CHARACTERISTICS: Fixed energy, 18 MeV protons, 8.5 MeV deuterons
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 8.5 Yes No
Maximum beam available (µA) 50 50
Typical beam employed (µA) 35 35
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
55 20 6 4 25
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 18 FDG daily, ten local
institutions/hospitals.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 2
� Gamma camera 15
� Single photon tomography (SPET) 6
� Positron emission tomography (PET)
– Clinical 3
– Small animal 3
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
433
427

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
428 434
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 80 97+ 1 500 Yes
No
20 Ne (d, α) 18 F 1.2 250
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 40 daily Yes No Yes No
DOPA 0.05 weekly Yes No Yes No
Setopirine 0.1-0.5 weekly Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
11
C-CFT,
Yes No Yes No
Raclopride
Altopene, SCH 50 mCi 10/week Yes No Yes No
11
CO 100 mCi 2/week Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
13
N2
13
N2H3
100 mCi
300 mCi
10/week
5/week
12
C(d,n)
16
O(p, α)
Yes
Yes
No
No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
C 15 O2
15
O2
H21
300 mCi
300 mCi
10/week
2/week
14 15
N(d,n) O
14 15
N(d,n) O
5 O 300 mCi 5/week
14 15
N(d,n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
0.037 Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

COUNTRY: UNITED STATES OF AMERICA USA-23
[1] INSTITUTE: Medi-Physics, Inc.
Amersham Healthcare
900 Durham Avenue
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Negative ion, fixed
field, fixed freq., var.
energy
South Plainfield, NJ 07080
+1 908 757 0500
Gordon Glass
Site Administration Manager
William McClain
YEAR OF: (I)
INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 30
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) Proprietary Yes No
Maximum beam available (µA)
Typical beam employed (µA)
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
production
h/week for
research
3 He
h/week for
maintenance
4 He
1989
h/week for
applications
Proprietary info
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Proprietary info
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
435
429

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
430 436
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-24
[1] INSTITUTE: Medi-Physics, Inc.
Amersham Healthcare
3350 Ridge Avenue
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Positive ion, variable
CYCLOTRON:
energy
Arlington Heights, IL 60004
+1 847 3988 400
Thomas Springer
Director of Operations
Brian Carus
YEAR OF: (I)
INSTALLATION
MANUFACTURER: Sumitomo & CGR (II) UPGRADE:
MODEL: PV-750
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) Proprietary Yes No
Maximum beam available (µA)
Typical beam employed (µA)
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
production
h/week for
research
3 He
h/week for
maintenance
4 He
1986
h/week for
applications
Proprietary info
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Proprietary info
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
437
431

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
432 438
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-25
[1] INSTITUTE: Medi-Physics, Inc.
Amersham Healthcare
3350 Ridge Avenue
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Positive ion, variable
CYCLOTRON:
energy
Arlington Heights, IL 60004
+1 847 3988 400
Thomas Springer
Director of Operations
Brian Carus
YEAR OF: (I)
INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL: MC-40
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) Proprietary Yes No
Maximum beam available (µA)
Typical beam employed (µA)
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
production
h/week for
research
3 He
h/week for
maintenance
4 He
1979
h/week for
applications
Proprietary info
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Proprietary info
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
439
433

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
434 440
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-26
[1] INSTITUTE: Medi-Physics, Inc.
Amersham Healthcare
900 Durham Avenue
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Positive ion,
Azimuthally varying
South Plainfield, NJ 07080
+1 847 3988 400
Gordon Glass
Site Administration Manager
William McClain
YEAR OF: (I)
INSTALLATION
MANUFACTURER:
field, isochronous
The Cyclotron
Corporation
(II) UPGRADE:
MODEL: MC-40
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
Typical beam employed (µA)
Proprietary Yes No
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
Proprietary info
production
research
maintenance applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Proprietary info
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
1973
441
435

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
436 442
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-27
[1] INSTITUTE: Mount Sinai Medical Center
4300 Alton Road
Miami Beach, FL 33140
TELEPHONE NO.:
E-MAIL ADDRESS:
+1 305 674 2465
FAX NO.:
+1 305 674 2428
[2] PERSON IN CHARGE:
Dr. Thomas E. Boothe
POSITION:
Director, Cyclotron/Radiochemistry
OTHER SENIOR STAFF:
Mike Plitnikes
NAME/POSITION
Patricia Smith
NAME/POSITION
Manny Tavana
[3] TYPE OF
Positive ion YEAR OF:
1972
CYCLOTRON:
(I) INSTALLATION
MANUFACTURER: The Cyclotron
Corporation
(II) UPGRADE:
MODEL: CS-30
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
Typical beam employed (µA)
Proprietary Yes No
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
Proprietary Proprietary Proprietary
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 67 Ga-chloride; 111 In-chloride;
201
Tl-chloride – world wide
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
443
437

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
438 444
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced):
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-28
[1] INSTITUTE: National Institute of Drug Abuse
NIDA/IRP, NIH
5500 Nathan Shock Drive, Room 405
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
Baltimore, MD 21224
+1 410 550 1440 (general)/ +1 410 550 2916 (cyclotron)
ahorti@intra.nida.nih.gov
+1 410 550 2724
Alane Kimes, PhD.
Acting Branch Chief
Andrew Horti, PhD., Chief Radiochemist
Carlo Contoreggi, MD, Authorized Radiation User/Nuclear
Medicine Physician
[3] TYPE OF
Negative ion YEAR OF: (I)
1997
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 111
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 25-40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20 0 8 20
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 0 Radiography: 0
Materials science: 0 Proton therapy: 0
Physics: 0 Neutron therapy: 0
Activation analysis: 0 Other (specify): 20: PET
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
445
439

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
440 446
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 12-15 95 1.1 200 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 4-8 1-2/week Yes No Yes No
18
F – 2-Fa 1 0-2/week Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Raclopride 4-8 0-6/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
n/a Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 0.7-1 0-30/week
15 15
N(p,n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Many research tracers labeled with 11 C and 18 F.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-29
[1] INSTITUTE: National Institute of Health
Building 10, Room 1C401, MSC 1180
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Bethesda, MD 20892
+1 301 496 0345
paul@nmdhst.cc.nih.gov
+1 301 402 3521
Dr. William Eckelman
Chief, PET Department
Paul S. Plascjak
YEAR OF: (I)
INSTALLATION
MANUFACTURER: (II) UPGRADE:
MODEL: PET Trace
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 16.5 8.4 Yes No
Maximum beam available (µA) 50 50
Typical beam employed (µA) 35 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
40 5 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 40 Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? ORNL - monthly;
NIST - yearly.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera 1
� Single photon tomography (SPET) 3
� Positron emission tomography (PET)
– Clinical 3
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1999
447
441

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
442 448
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 40 95 1.5 600 Yes
No
20 Ne (d, α) 18 F 10
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 20 1/day Yes No Yes No
Dopamine 0.3 1/week Yes No Yes No
DOPA 0.3 1/week Yes No Yes No
FPTZTP 0.2 1/week Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Raclopride 1 1/week Yes No Yes No
Palmitic acid 1 2/week Yes No Yes No
Aracidonic 0.5 4/week Yes No Yes No
CO 2 2/week Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 1.5 10/week
16 13
O(p, α) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water Continuous daily
14 15
N(d, n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y 0.75 1/week Yes No Yes No
94m
Tc 1.0 1/week Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
1.5 1/month Yes No Yes No
201
Tl Yes No Yes No
211
At 1.5 1/month Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-30
[1] INSTITUTE: National Institute of Health
Building 10, Room 1C401, MSC 1180
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Fixed energy
CYCLOTRON: compact
MANUFACTURER: Japan Steel Works,
Ltd.
Bethesda, MD 20892
+1 301 496 0345
+1 301 402 3521
Dr. William Eckelman
Chief, PET Department
Paul S. Plascjak
YEAR OF: (I)
INSTALLATION
(II) UPGRADE:
MODEL: JSW-1710
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 17.5 9.8 Yes No
Maximum beam available (µA) 150 150
Typical beam employed (µA) 50 50
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
72 (6 days/ week) ~ 35 4
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 18 F FDG provided to one centre
1/week
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 3
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
1985
449
443

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
444 450
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Dopa Yes No Yes No
Dopamine Yes No Yes No
F Pr TZPZ Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
6 - 18 F – Cylofoxy.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-31
[1] INSTITUTE: National Institute of Health
Building 10, Room 1C401, MSC 1180
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Fixed energy
CYCLOTRON: compact
MANUFACTURER: The Cyclotron
Corporation
MODEL: CS 30
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Bethesda, MD 20892
+1 301 496 0345
paul@nmdhst.cc.nih.gov
+1 301 402 3521
Dr. William Eckelman
Chief, PET Department
Paul S. Plascjak
YEAR OF: (I)
INSTALLATION
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 26.5 14.8 38.1 29.6 Yes No
Maximum beam available (µA) 200 300 135 90
Typical beam employed (µA) 60 100 60 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
72 (6 days/week) ~ 35 4
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 18 FDG provided to one centre,
1/week
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site? Research/diagnosis on site.
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 3
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1985
451
445

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
446 452
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Dopa Yes No Yes No
Dopamine Yes No Yes No
F Pr TZPZ Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
6 - 18 F – Cylofoxy.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY UNITED STATES OF AMERICA USA- 32
[1] INSTITUTE: National Superconducting Cyclotron Laboratory
Michigan State University, 1 Cyclotron
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OFCYCLOTRON:
MANUFACTURER:
MODEL:
Superconducting
magnet cyclotron
In-house, K1200
East Lansing, MI 48824-1321
+1-517-355-9671
gelbke@nscl.msu.edu
+1-517-353-5967
Dr. C.-K. Gelbke
Director
Dr. Peter S. Miller / Head, Operations Department
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
[4] CYCLOTRON CHARACTERISTICS:
1200 q 2 /A 2 MeV/nucleon, focusing limit 400 q/A MeV/nucleon
16 136 209
O 150 MeV/u, Xe 120 MeV/u, Bi 80 MeV/u for example
1 2
H H
3 He
4 He
1980-1987
1996-2000
Dual Beams
Beam energies (MeV) Yes No
Maximum beam available (µA)
Typical beam employed (µA)
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week
for radionuclide
production
Hours/week for research Hours/week for
maintenance
Hours/week for
applications
156 156 12
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
Production of rare isotope
beams by nuclear
fragmentation process
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
Yes No
If yes and available, name of institution/s & how often?
We supply beams of rare isotopes to users, many from other institutions.
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
[11] Type of imaging equipment available on-site Number of
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical Small animal Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
453
447

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
448 454
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
Frequency of
production
Used on site Distribution/
sales
18 FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/G
Bq
if
availabl
e
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS:(e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)

2005 COUNTRY UNITED STATES OF AMERICA USA-33
[1] INSTITUTE: National Superconducting Cyclotron Laboratory
Michigan State University, 1 Cyclotron
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OFCYCLOTRON:
MANUFACTURER:
MODEL:
[4] CYCLOTRON CHARACTERISTICS:
Superconducting
magnet cyclotron
In-house, K500
East Lansing, MI 48824-1321
+1-517-355-9671
gelbke@nscl.msu.edu
+1-517-353-5967
Dr. C.-K. Gelbke
Director
Dr. Peter S. Miller / Head, Operations Department
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
520 q 2 /A 2 MeV/nucleon, focusing limit 160 q/A MeV/nucleon
1 2
H H
3 He
4 He
1977-1981
1996-2000
Dual Beams
Beam energies (MeV) Yes No
Maximum beam available (µA)
Typical beam employed (µA)
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week
for radionuclide
production
Hours/week for research Hours/week for
maintenance
Hours/week for
applications
156 156 12
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
Injector for K1200cyclotron
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried Yes No
out on-site?
[11] Type of imaging equipment available on-site Number of
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
455
449

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
450 456
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS:(e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)

2005 COUNTRY: UNITED STATES OF AMERICA USA-34
[1] INSTITUTE: North Shore University Hospital
Research Department - Cyclotron/ PET Facility
350 Community Drive
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
Manhasett, NY 11021
+1 516 562 1055
rdahl@nshs.edu
+1 516 562 1120
Dr. J. Robert Dahl
OTHER SENIOR STAFF:
NAME/POSITION
Thomas Chaly
[3] TYPE OF
Positive ion YEAR OF: (I)
1987
CYCLOTRON:
INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL: MC-17F
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 17.5 8.75 17.5 Yes No
Maximum beam available (µA) 180 180
Typical beam employed (µA) 30-40 30-40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20 20 4, plus 2 weeks/year
for periodic
maintenance
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Only to research collaborators
with continuing joint projects.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 1
� Gamma camera 1
� Single photon tomography (SPET) 1
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
457
451

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
452 458
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-35
[1] INSTITUTE: Northern California PET Imaging Center
3195 Folsom Boulevard
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Sacramento, CA 95816
+1 916 737 3200
Dr. Peter Valk
Mason Jones
Negative ion YEAR OF: (I)
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA)
Typical beam employed (µA) 20-40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
10 10 2
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 18 F-FDG, 1/month
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 1
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1992
459
453

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
454 460
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
F-FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
13
N-ammonia Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
15 O-water
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-36
[1] INSTITUTE: Oak Ridge National Laboratory
Bldg. 6000, MS 6368
Oak Ridge, TN 37831-6368
TELEPHONE NO.:
E-MAIL ADDRESS:
+1 423 574 4111
FAX NO.:
+1 423 574 1268
[2] PERSON IN CHARGE:
B.A. Tatum
POSITION:
Engineering Manager
OTHER SENIOR STAFF:
NAME/POSITION
S.W. Mosko
[3] TYPE OF
K=100 Isochronous YEAR OF: (I)
1960
CYCLOTRON:
INSTALLATION
MANUFACTURER:
MODEL:
ORNL (II) UPGRADE:
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) < 60 < 40 Yes No
Maximum beam available (µA) < 100 < 200
Typical beam employed (µA) < 50 < 100
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20 40
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
461
455

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
456 462
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-37
[1] INSTITUTE: PET Net - Chicago
200 E. Howard Street No. 240
Des Plaines, IL 60018
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
+1 847 297 1322
Mr. Russ Greenberg
Manager
Clyde Cole
[3] TYPE OF
Negative ion YEAR OF: (I)
1995
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
11 Yes No
Typical beam employed (µA) 20-40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
10 10 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 18 F-FDG, 5 × per week
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
463
457

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
458 464
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
F-FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-38
[1] INSTITUTE: PETNet Pharmaceutical Services
1350 Manufacturing Drive, Suite 105
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
Dallas, TX 75207
+1 214 741 2075
steve.torres@cti-pet.com
+1 214 741 9323
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Mr. Steve Torres
[3] TYPE OF
YEAR OF: (I)
2001
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 111
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
40 33 18
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
465
459

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
460 466
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 133 96 1.3 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 59 3 /day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-39
[1] INSTITUTE: PETNet Pharmaceutical Services
1350 Manufacturing Drive, Suite 105
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Dallas, TX 75207
+1 214 741 2075
steve.torres@cti-pet.com
+1 214 741 9323
Mr. Steve Torres
YEAR OF: (I)
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 111
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
40 33 18
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1999
467
461

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
462 468
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 133 96 1.3 Yes
No
20 Ne (d, α) 18 F
16 18
O (α, d) F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 59 3 /day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-40
[1] INSTITUTE: PET Net/VAMC Palo Alto
Nuclear Medicine Service (115)
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
3801 Miranda Avenue
+1 415 493 5000
pa-pet@ix.netcom.com
OTHER SENIOR STAFF:
NAME/POSITION
Dr. Henry C. Padgett
Manager
Dave Wilson
[3] TYPE OF
Negative ion YEAR OF: (I)
1996
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
11 Yes No
Typical beam employed (µA) 25-40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
5-15 5-15 ~ 0
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
15
O
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 2-3/ week
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 1
� Gamma camera
� Single photon tomography (SPET) 3
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
469
463

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
464 470
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-41
[1] INSTITUTE: Regional Nuclear Pharmaceutical, LLC
1224 3rd Avenue South
University Park
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Birmingham, Alabama 35233
+1 205 322 4252
jhaynes@nti.net
+1 205 322 4859
Mr. John Haynes
Director of Operations
YEAR OF: (I)
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 111
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 100
Typical beam employed (µA) 80
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
30 25 0 2 0
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
18
F production
25/week
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? New Orleans, Regional PET;
Memphis Regional PET; Jeff Anderson Regional Medical Centre.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
2000
471
465

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
466 472
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 37 >95 1 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
18
FDG 55 2/day Yes No Yes No $750/
dose
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yield on batch
(GBq)
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Frequency of
production
Used on site Distribution/
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-42
[1] INSTITUTE: Saint Louis University
Health Sciences Center, School of Medicine
Division of Nuclear Medicine
3635 Vista Avenue at Grand Blvd.
P.O. Box 15250
St. Louis, MO 63110-0250
TELEPHONE NO.:
E-MAIL ADDRESS:
+1 314 577 8801
FAX NO.:
+1 314 268 5486
[2] PERSON IN CHARGE:
Dr. Ranajit K. Bera
POSITION:
Assistant Professor
OTHER SENIOR STAFF:
NAME/POSITION
Dr. James W. Fletcher, Director
[3] TYPE OF
Negative ion YEAR OF: (I)
1991
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 80
Typical beam employed (µA) 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
Radiopharmaceuticals 20 h/week
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) Advanced
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
473
467

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
468 474
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 40 95 0.38 140 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 15-20 everyday Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on
(list)
batch (GBq)
13
NH3 0.8
15 O RADIOPHARMACEUTICALS PRODUCED
Frequency of
production
Nuclear reaction used Distribution/
sales
13 13
C(p,n) N Yes No
Yes No
Yes No
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
H2 15 O 15
15 15
N(p,n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
18 F - Cyclofoxy
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-43
[1] INSTITUTE: Saint Joseph's Positron Center
3003 W. Dr. Martin Luther King, Jr. Boulevard
Tampa, FL 33607-4227
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
NAME/POSITION
+1 813 876 5620
John Mather
Kathie Krista
Mike Mosley
John O'Connen
[3] TYPE OF
Negative ion YEAR OF: (I)
1989
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
11 Yes No
Typical beam employed (µA) 20-40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
10 10 2
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 18 F-FDG, 5 days/week
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
Yes No
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
475
469

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
470 476
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-44
[1] INSTITUTE: State University of New York at Buffalo
Department of Nuclear Medicine
105 Parker Hall, 3435 Main Street
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Buffalo, NY 14214-3007
+1 716 838 5889
fred@nucmed.buffalo.edu
+1 716 838 4918
Prof. R. E. Ackerhalt
Director of the Cyclotron Facility
Michael S. Haka
Negative ion YEAR OF:
CYCLOTRON:
(I) INSTALLATION
1992
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 30
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 15-30 Yes No
Maximum beam available (µA)
Typical beam employed (µA)
0-450
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
164 8 ~ 4
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
103
Pd
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 18 F-FDG VA, daily; 13 Nammonia,
weekly; - 18 F-FDG, MFH 3-4 x/week/Roswell 1/week/Biomedical Research, 1-
2/week
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 1
� Gamma camera 15
� Single photon tomography (SPET) 22
� Positron emission tomography (PET) 3
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
477
471

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
472 478
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 1/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 1/week Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
Water
CO
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
62 Cu, 62 Zn
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY UNITED STATES OF AMERICA USA-45
[1] INSTITUTE: Texas A&M University
Cyclotron Institute
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
MANUFACTURER:
K500
Superconducting
TAMU
College Station, TX 77843
979-845-1411
office@comp.tamu.edu
979-845-1899
Robert Tribble
Director
Don May
Fred Abegglen
George Kim
Henry Clark
YEAR OF:
(I) INSTALLATION:
MODEL:
K500
(II) UPGRADE:
none
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He
Dual Beams
Beam energies (MeV) 10-70 55-70 MeV/nuc 25-40 15-70 Yes No
MeV/nuc
MeV/nuc MeV/nuc
Maximum beam available (µA) 0.2 1 1 1
Typical beam employed (µA) 0.01 0.01 0.01 0.05
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week Hours/week for research Hours/week for Hours/week for
for radionuclide
production
maintenance applications
168 0 69% 1% 30%
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: 0 Radiography: 0
Materials science: 30% Proton therapy: 0
Physics: 69% Neutron therapy: 0
Activation analysis: 0 Other (specify) 1%
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] Type of imaging equipment available on-site Number of
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
1988
479
473

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
474 480
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS:
produced)
(e.g., you may add names of additional labelled compounds/radiopharmaceuticals being

2005 COUNTRY: UNITED STATES OF AMERICA USA-46
[1] INSTITUTE: The Christ Hospital
2139 Auburn Avenue
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Cincinnati, OH 45219
+1 513 585 0836
kemmet@healthall.com
+1 513 585 0835
Mr. Thomas G. Kemme
Manager
Ms. Carla C. Pemberton, RPh.
Mr. George H. Day, RPh.
[3] TYPE OF
Negative ion YEAR OF: (I)
1991
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 20
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
12 12 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 13
F- FDG, NH3
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? University of Cincinnati –
2/week; Fort Hamilton Hughes Hostpital – 1/month; Proctor & Gamble – 1/month
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
481
475

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
476 482
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 32 > 95 0.33 100 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 10 daily Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Acetate 30 1-2/yr Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 1.2 1/week Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-47
[1] INSTITUTE: The Queen's Medical Center
1301 Punchbowl Street
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
Honolulu, HI 96813
+1 808 537 7077
pmcguigan@queens.org
+1 808 585 5095
Pat McGuigan
Manager
OTHER SENIOR STAFF:
NAME/POSITION
Marc Coel, MD
[3] TYPE OF
Negative ion YEAR OF: (I)
1998
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 111
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) (yes) Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
5 1 5 0
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[F-18] Choline
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Tripler Hospital and Kuakini
Hospital
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
483
477

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
478 484
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F > 95 1.1 200 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 9 1/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
[F-18] Choline
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-48
[1] INSTITUTE: Theragenics Corporation
5325 Oakbrook Parkway
Norcross, GA 30093
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
+1 770 381 8447
[2] PERSON IN CHARGE:
Tony Longo
POSITION:
Cyclotron Facility Manager
OTHER SENIOR STAFF:
Tom West; Ty Tobin
NAME/POSITION
Mr. Joe Rodgers; J. Hwung
[3] TYPE OF
Negative ion YEAR OF: (I)
1996
CYCLOTRON:
INSTALLATION
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 18+
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 Yes No
Maximum beam available (µA) various
Typical beam employed (µA) N/A
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
144-168 Typical 0-36
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Medical; Typical 1 to 10 / month/
client
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
Number
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
485
479

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
480 486
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd 10 - 60 1/week Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Brachytherapy
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-49
[1] INSTITUTE: Theragenics Corporation
5325 Oakbrook Parkway
Norcross, GA 30093
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
+1 770 3818 447
[2] PERSON IN CHARGE:
Tony Longo
POSITION:
Cyclotron Facility Manager
OTHER SENIOR STAFF:
Tom West; Ty Tobin
NAME/POSITION
Mr. Joe Rodgers; J. Hwung
[3] TYPE OF
Negative ion YEAR OF:
CYCLOTRON:
(I) INSTALLATION
1994
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 18+
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 Yes No
Maximum beam available (µA) various
Typical beam employed (µA) N/A
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
144-168 Typical 0-36
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Medical; Typical 1 to 10 / month/
client
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
–Clinical
–Small animal
–Plant biochemistry
Number
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
487
481

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
482 488
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd 10 - 60 1/week Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Brachytherapy
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-50
[1] INSTITUTE: Theragenics Corporation
5325 Oakbrook Parkway
Norcross, GA 30093
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
+1 770 381 8447
[2] PERSON IN CHARGE:
Tony Longo
POSITION:
Cyclotron Facility Manager
OTHER SENIOR STAFF:
Tom West; Ty Robin
NAME/POSITION
Joe Rodgers; J. Hwung
[3] TYPE OF
Negative ion YEAR OF:
CYCLOTRON:
(I) INSTALLATION
1992
MANUFACTURER: IBA, s.a. (II) UPGRADE:
MODEL: Cyclone 18+
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 Yes No
Maximum beam available (µA) various
Typical beam employed (µA) N/A
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
144-168 Typical 0-36
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Medical; Typical 1 to 10 / month/
client
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
489
483

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
484 490
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd 10 - 60 1/week Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Brachytherapy
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-51
[1] INSTITUTE: University of California at Los Angeles
Biomedical Cyclotron
10833 Le Conte Avenue
Los Angeles, CA 90095
TELEPHONE NO.:
E-MAIL ADDRESS:
+1 310 825 6231
FAX NO.:
+1 310 825 4517
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
N. Satyamurthy
[3] TYPE OF
Negative ion YEAR OF: (I)
1994
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 100
Typical beam employed (µA) 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
40 20 10 2-3
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
Several 18 F and 11 C labeled radiopharmaceuticals
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 3
– Small animal 3
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
491
485

18F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
486 492
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 40 95 0.8 15 750 5 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 20 10/week Yes No Yes No
Variety of 18 Flabeled
prods.
10/week Yes No Yes No
Yes No Yes No
Yes No Yes No
11 C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
11
C-Acetate 10 2/week Yes No Yes No
Variety of 11 Clabeled
prods.
4/week Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 3 20/week 16 13
O(p, α) N Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
H2O 4 10/week
15 15
N(p, n) O
O2 4 3/week
CO 4 3/week
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-52
[1] INSTITUTE: University of California-Irvine
Brain Imaging Centre
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Irvine, CA 92697
+1 714 824 2018
aanajafi@uci.edu
+1 714 824 2230
Dr. Ahmod A. Najafi
Positive ion YEAR OF
CYCLOTRON:
(I) INSTALLATION
1988
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL: MC 17
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 8-10 Yes No
Maximum beam available (µA) 20
Typical beam employed (µA) 2-3
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
12 12 2 -3
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) (yes)
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
493
487

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
488 494
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Dopa Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-53
[1] INSTITUTE: University of Iowa
PET Imaging Centre
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Positive ion, sectorfocused,
resistive
magnet
Iowa City, IA 52242
+1 319 356 4100
richard-hichwa@uiowa.edu
+1 319 353 6512
Professor Richard D. Hichwa
Director
G. Leonard Watkins
Laura Boles Ponto
Mark T. Madsen
YEAR OF: (I)
INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL: MC-17 F
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 18 7.3 (fixed energy) Yes No
Maximum beam available (µA) 1-70 1-70
Typical beam employed (µA) 25-50 100 10-15
max 100 max
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
> 40 20-30 < 1 target
maintenance 1/year
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site? Medical research/diagnosis
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1990
495
489

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
490 496
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Mehionine Yes No Yes No
Acetate Yes No Yes No
CO, CO2 Yes No Yes No
Receptor
ligands
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
Water
CO, CO2
O2
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
48 V
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-54
[1] INSTITUTE: University of Michigan
3480 Kresge III
Ann Arbor, MI 48109-0552
TELEPHONE NO.:
E-MAIL ADDRESS:
+1 313 763 9244
FAX NO.:
+1 313 764 0288
[2] PERSON IN CHARGE:
Professor Michael R. Kilbourn
POSITION:
Director, PET Chemistry
OTHER SENIOR STAFF:
Dr. Robert Koeppe
NAME/POSITION
Mr. James Moskwa
[3] TYPE OF
Medical YEAR OF:
1982
CYCLOTRON:
(I) INSTALLATION
MANUFACTURER: The Cyclotron
Corporation
(II) UPGRADE:
MODEL: CS-30
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 26.0 15.0 38.0 30.0 Yes No
Maximum beam available (µA) 200 300 100 90
Typical beam employed (µA) 30 30 50 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
15 12 4
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 3
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
497
491

18F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
492 498
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Epinephrine Yes No Yes No
Pseuolophedrine Yes No Yes No
Diahydiotetaben
azine
Yes No Yes No
Acetate Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
Water
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
62 Zn
Price/
Bq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY UNITED STATES OF AMERICA USA-55
[1] INSTITUTE: University of Pennsylvania
Department of Radiology
420 Curie Blvd
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
[3] TYPE OFCYCLOTRON:
MANUFACTURER:
MODEL:
Positive Ion
Japan Steel Works
3015 BC
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Philadelphia, PA 19104
215-662-7550
freifeld@mail.med.upenn.edu
215-662-7551
Richard Freifelder, Ph.D.
Senior Research Investigator,
Cyclotron Facility Manager
Joel S. Karp, Ph.D.
Harry White
Larry Toto
YEAR OF:
(I) INSTALLATION:
(II) UPGRADE:
Dual Beams
Beam energies (MeV) 18, 22, 30 11 Yes No
Maximum beam available (µA) 30 15
Typical beam employed (µA) 10-15 10
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week or
Hours/week for research Hours/week for Hours/week for
radioproduction
maintenance applications
40 30 3
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)PET Tracers 30
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18-F, 11-C Choline, FIAU, Fallypride, 11-C Cartentenil
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] Type of imaging equipment available on-site Number of
� 511 KeV coincidence
� Gamma camera 3
� Single photon tomography (SPET) 5
� Positron emission tomography (PET) 5
– Clinical 4
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1985
499
493

18F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
494 500
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 55 97 0.6 cc 250 g Yes
No
Ne (d, α) 18 F 3.7 50 cc Ne
gas
16 O (α, x) 18 F n/a
18 F RADIOPHARMACEUTICALS PRODUCED
Name Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 18 Daily Yes No Yes No
18
F-DOPA 0.37 Once/week Yes No Yes No
18
F-FHBG 0.19 Once/week Yes No Yes No
18
F-FLT 0.19 Once/week Yes No Yes No
11 C RADIOPHARMACEUTICALS PRODUCED
Name
(list)
11
C-
Raclopride
Yield on batch Frequency of Used on site Distribution/
(GBq)
production
sales
0.19 Once/month Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name Typical yield on Frequency of
(list)
batch (GBq) production
13
N-ammonia 3.7 Once/month
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Yes No Yes No
Yes No Yes No
Yes No Yes No
Nuclear reaction used Distribution/
sales
12 13
C(p,n) N Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS:(e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)
EF5 (18-F)
15-O water
18-F NaF

2005 COUNTRY: UNITED STATES OF AMERICA USA-56
[1] INSTITUTE: University of Southern California
1510 San Pablo, #350
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Los Angeles, CA 9003
+1 213 342 5884
pconti@hsc.usc.edu
+1 213 342 5778
Dr. Peter S. Conti
Director, PET Imaging & Radiological Resources
James R. Bading; Miar Alauddin
Mr. John Fissikis; Mr. Keith Higa
Negative ion YEAR OF:
CYCLOTRON:
(I) INSTALLATION
1990
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 111
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 150
Typical beam employed (µA) 20-40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
20 15 3
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 18 F-FDG daily
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site? Both on and off site
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
501
495

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
496 502
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
Water
O
CO, CO2
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
64 Cu Yes No Yes No
67 Ga Yes No Yes No
86 Y Yes No Yes No
94m Tc Yes No Yes No
103 Pd Yes No Yes No
111 In Yes No Yes No
123
I
124
I
sales
Yes No Yes No
Yes No Yes No
201 Tl Yes No Yes No
211 At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-57
[1] INSTITUTE: University of Tennesse Medical Centre
Biomedical Imaging Center
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
1924 Alcoa Highway, Knoxville, TN 37920
+1 865 544 9818 or 865 544 9697
Longford@scanner.hosp.utk.edu OR
desmond.longford@petnepharmaceutical.com
+1 865 544 8395
C.P.D. Longford
Manager
K.F. Hubner
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Negative ion YEAR OF:
CYCLOTRON:
(I) INSTALLATION
1987
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112 2000 - two (2) high pressure target; APS power supply upgraded
2001 - new main magnet power supply - solid state; new
automated chemistry equipment
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
11.2 Yes No
Typical beam employed (µA) 32/target
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
30-40 30-40 1-2 4-8 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Daily deliveries of 18 FDG to
hospitals within 4-5 km radius. Currently have 20 customers, shipping up to 20 doses/day
with planned expansion to ship 60 doses/day.
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 1
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
503
497

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
498 504
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 65 > 94 0.90 5 1200 None Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 30-60 2-3/day Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
ACBC 3.0 5-10/year Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Planned: 18 F -BPA and DOPA – not yet available.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-58
[1] INSTITUTE: University of Texas Houston
[2]
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
NAME/POSITION
NAME/POSITION
[3] TYPE OF
Variable energy
CYCLOTRON:
isochronous
6431 Fannin Street, Houston, TX 77030
+1 713 500 7755
carlos.gonzalez-lepera@uta.tmc.edu
+1 713 500 7771
Carlos Gonzalez Lepera
Associate Professor and Executive Director
Nancy Haberman, Chemist
Kevin Grilley, Radiopharmacist
Russell Hildebrandt, Radiopharmacist
Isidoro Vaquila, Cyclotron Engineer
David Andews, Cyclotron Operator
YEAR OF:
(I) INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL: MC-40
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 40 20 40 Yes N
Maximum beam available (µA) 150 40 30
Typical beam employed (µA) 40 15 15
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
50 25 10 4 5
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 1 Radiography:
Materials science: 1 Proton therapy:
Physics: 1 Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
22
Na, 0.037
GBq
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
124 211
I , At
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Hospitals and PET Centres
throughout Southeast Texas
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal 1
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1983
505
499

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
500 506
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 100 95 1.4 300 Ye
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 50 2/day Yes No Yes No
NaF 50 1/day Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 4 6/day 16 13
0(p, α) N Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 4 1/day
14 15
N(d, n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga 555 Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In 370 Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-59
[1] INSTITUTE: University of Texas Research Imaging Center
Health Science Center, San Antonia
7703 Floyd Curl Drive
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Fixed energy,
isochronous, positive
ion
San Antonio, TX 78284
+1 210 567 8190
jerabet@uthscsa.edu
+1 210 567 8152
Dr. Peter Fox
Director
Paul Jerabbk
YEAR OF:
(I) INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL: MC-17F
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 17.2 8.6 Yes N
Maximum beam available (µA) < 10 < 10
Typical beam employed (µA) 10-50 10-40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
3-5 3-5 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Number
Positron emission tomography (PET)
- Clinical
- Small animal
- Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1991
507
501

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
502 508
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Acetate Yes No Yes No
Methionine Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
Water
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA SA-60
[1] INSTITUTE: University of Washington Medical Centre
Department of Radiation Oncology
Box 356043, Room NN-136, 1959 NE Pacific Street
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Compact room
temperature
cyclotron
Seattle, WA 98195-6043
+1 206 548 4136
risler@radonc.washington.edu
+1 206 548 6218
Dr. Ruedi Risler
Senior Cyclotron Engineer
Professor Kenneth A. Krohn
Professor Jeanne A. Link
YEAR OF:
(I) INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL:
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 50.5 Yes No
Maximum beam available (µA) 60
Typical beam employed (µA) 60
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research maintenance applications
10 3 6 30
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: 1 Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy: 30
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No 35
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 F, 11 C, 15 O, 13 N, 86 Y, 99 Tc, 124 I, 19 Ne
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
511 KeV coincidence 0
Gamma camera 6
Single photon tomography (SPET) 2
Positron emission tomography (PET) 1
–Clinical
–Small animal
–Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1983
509
503

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
504 510
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 15-20 95 3 No 60 None Yes
No
Ne (d, α) 18 F No
16 O (α, x) 18 F No
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 5 2/day Yes No Yes No
FES 1 3/month Yes No Yes No
FM180 1 3/month Yes No Yes No
FLT 1 3/month Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Glucose 1 1/month Yes No Yes No
Thyamidine 1 3/momth Yes No Yes No
MHED 1 4/month Yes No Yes No
CGP12177 2 8/month Yes No Yes No
Flumazenile 1 1/month Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
H2O
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
O2
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y 2/yr Yes No Yes No
94m
Tc 2/yr Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
planned Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY UNITED STATES OF AMERICA USA-61
[1] INSTITUTE:
MEDICAL PHYSICS DEPARTMENT
UNIVERSITY OF WISCONSIN, 1530 MEDICAL SCIENCE CENTER
1300 UNIVERSITY AVE, MADISON, WI, 53706, A
TELEPHONE NO.:
608-263-3910
E-MAIL ADDRESS:
rnickles@wisc.edu
FAX NO.:
FAX 608-262-2143
[2] PERSON IN CHARGE:
RJ Nickles
TITLE/POSITION:
Professor of Medical Physics
OTHER SENIOR STAFF:
Brad Christian, Assistant Professor of Medical Physics
NAME/POSITION
Onofre DeJesus, Professor of Medical Physicss
[3] TYPE OFCYCLOTRON: 11 MeVproton YEAR OF:
MANUFACTURER: CTI Inc
(I) INSTALLATION:
1985
MODEL:
112 (first prototype) (II) UPGRADE:
2005
[4] CYCLOTRON CHARACTERISTICS:
11 MEV PROTON, NEGATIVE ION, 50 MICROAMPS ONTO 4 TARGET POSITIONS, ONE A VERTICAL
BEAM PORT FOR MOLTEN TARGETS
1
H
2
H
3
He
4
He
Dual Beams
Beam energies (MeV) 11 Yes x No
Maximum beam available (µA) 50
Typical beam employed (µA) 20-30
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week or
Hours/week for research Hours/week for Hours/week for
radiopoduction
maintenance applications
10-20 10 5 2
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify) teaching
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes x No Ce-139
Intense neutron beam? (specify average En = ?) Yes x No Protons on Be-9
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
Br-76, Cl-34m, O-14,
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Stanford (monthly)
TRIUMF (soon to start)
Yes x No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried out
on-site?
Yes x No
[11] Type of imaging equipment available on-site
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
Number of
–Clinical, Small animal, Plant biochemistry 2
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
[F-18] atrazine (Roundup) leachng into ground water
Yes x No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes x No
[14] Is the cyclotron used for targetry development? Yes x No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes x No
[16] Does your institute accept IAEA research fellows for training/experience? Yes x No
511
505

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
506 512
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F 20 30-50% 0.9 ml 20 ml 100 30 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Purchase
commercially
Yes No Yes No
F-DOPA, FMT 3 30 Yes x No Yes No
fallypride 2 50 Yes x No Yes No
Fatty acids 2 2 Yes x No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
SCH 23,390 2 10 Yes x No Yes No
Raclopride 2 15 Yes x No Yes No
PK 11195 2 15 Yes x No Yes No
Methyphenidate
2 15 Yes x No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
NH3 4 5 Protons on O-16 water Yes No x
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu 20-40 10 Yes x No Yes x No $162/
GBq
67
Ga Yes No Yes No
86
Y 2 5 Yes x No Yes No
94m
Tc 4 5 Yes x No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
0.2-0.4 10 Yes x No Yes x No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS:(e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Over the period of 1971 to the present, about 120 radioisotopes have been studied, making about over hundred
labeled compounds. (Nickles RJ, . Production of a Broader Palette of PET Tracers. J Lab Comp
Radiopharmaceuticals 46, 1-27: 2003

2005 COUNTRY: UNITED STATES OF AMERICA USA-62
[1] INSTITUTE: VA Medical Centre (11P)
1 Veterans Drive
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
NAME/POSITION
[3] TYPE OF
CYCLOTRON:
Minneapolis, MN 55417
+1 612 725 2230
sajjad@euler.pet.med.va.gov
+1 612 725 2068
Dr. David Rotenberg
Mr. Rashid Syed
Ms. Carroll Arnett
E. Akguen
Munawwar Sajjad
Positive ion YEAR OF: (I)
INSTALLATION
MANUFACTURER: Scandinotrix (II) UPGRADE:
MODEL: MC-40
[4] CYCLOTRON CHARACTERISTICS:
1 H
2 H
Dual Beams
Beam energies (MeV) 40 20 Yes N
Maximum beam available (µA) 40 50
Typical beam employed (µA) 25 30
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide
h/week for h/week for
h/week for
production
research
maintenance applications
30 15 2 6
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other If yes and available, name of institution/s & Yes No
institutions?
how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
3 He
4 He
1985
513
507

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
508 514
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 15 > 95 1.2 100 Yes
No
Ne (d, α) 18 F 11 99.999
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 6.5 3/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Acetate 1.8 on demand Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia 2.2 5/week
16 13
O(p,a) N Yes No
Yes No
Yes No
15 O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
15
O Water 6.0 36/week
14 15
N(d,n) O
14
O Water 3.5 on demand
14 14
N(p,n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-63
[1] INSTITUTE: VAMC & University of Pittsburgh Medical Facility
PET Center -9B
200 Lothrop Street
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Pittsburg, PA 15213
+1 412 647 0736
mathis@vad.arad.upmc.edu
+1 412 647 0700
Professor Chet Mathis
Co-Director, PET Facility
Professor David Townsend, Co-Dir., PET Facility
Negative ion YEAR OF:
1991
CYCLOTRON:
(I) INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 80
Typical beam employed (µA) 40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
35 20 15

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
510 516
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 22 > 95 0.3 200 Ye
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 7 5/week Yes No Yes No
18
F-Altanarin 2 2/week Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Flumezenil 4 1/week Yes No Yes No
McN 5652 4 2/week Yes No Yes No
Way 100635 1 4/week Yes No Yes No
PMD 4 4/week Yes No Yes No
Raclopride 3 10/week Yes No Yes No
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
NH3 3 4/week
16 13
O(p,a) N Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
H2O
O2
4-20
4-10
20/week
5/week
15 15
N(p,n) O
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-64
[1] INSTITUTE: Vanderbilt University Medical Center
Radiology Department
100 Medical Center South
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
NAME/POSITION
Nashville, TN 3723206315
+1 615 3220508
jim.patton@mcmail.vanderbilt.edu
Dr. Ronald G. Manning
Jeff Clanton
Jeff Clauton, ominique Delbeke
[3] TYPE OF
Negative ion
Robert Kessler
YEAR OF: (I)
1989
CYCLOTRON:
INSTALLATION
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA)
Typical beam employed (µA)
80
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
25 25 20
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? PETNet Site; Several Customers
>15
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site? Both on & off sites.
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence 1
� Gamma camera
� Single photon tomography (SPET) 4
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
517
511

18F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
512 518
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBqe
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITES STATES OF AMERICA USA-65
[1] INSTITUTE: Weill Medical College at Cornell University and
Memorial Sloan Kettering Cancer Center Consortium
1300 York Avenue
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
New York, NY 10021
+1 212 639 2458
finnr@msbcc.org
+1 212 717 3821
Dr. Ron Finn
Head, Cyclotron Division
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
Yiauchung Sheh, MS, Senior Cyclotron Engineer
[3] TYPE OF
Negative Ion YEAR OF:
Ongoing and in progress
CYCLOTRON:
(I) INSTALLATION
(2001)
MANUFACTURER: EBCO Industries (II) UPGRADE: Incorporation of external
beam
MODEL: TR 19/9 line with target changer
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
Typical beam employed (µA)
Yes No
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: 10% anticipated Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
Radionuclide preparation
90% anticipated
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? On scientific collaborative basis
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
Number
– Clinical
– Small animal
– Plant biochemistry
1
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
519
513

18F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
514 520
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F >95 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
69
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Imaging Center building completion scheduled for October 2001. Cyclotron already in vault, awaiting building service
availability for start of the assembly.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-66
[1] INSTITUTE: West Virginia University Hospital PET Centre
P.O. Box 9236
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
Morgantown, WV 26506-9236
+1 304 293 7798
smazza@wvuhscl.hsc.wvu.edu
+1 304 293 7142
Dr. Naresh C. Gupta
Director
Mr. Samuel M. Mazza
Mr. Raymond R. Raylman
YEAR OF:
CYCLOTRON:
Negative ion, dual
beam
(I) INSTALLATION
1995
MANUFACTURER:
MODEL:
General Electric (II) UPGRADE:
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV)
Maximum beam available (µA)
16.5 8.5 Yes No
Typical beam employed (µA) 20 10
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
5 5 1
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? 18 F-Fluoride – irregularly; 18 F-
FDG - planned
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
521
515

18F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
516 522
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
Ammonia Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
Water
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-67
[1] INSTITUTE: William Beaumont Hospital
Department of Nuclear Medicine
3601 West Thirteen Mile Road
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
Royal Oak, MI 48083-6769
+1 313 551 831
Dr. Ram B. Sharma
Radiochemist
[3]
OTHER SENIOR STAFF:
NAME/POSITION
TYPE OF
Negative ion YEAR OF:
CYCLOTRON:
(I) INSTALLATION
1991
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 20-35
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
13 13 2
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Nucl. Med. 40 Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
11 15
C and O
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET) 1
– Clinical
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
523
517

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
518 524
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F 30 95-98 0.3 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 16/batch 5/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/
(list)
batch (GBq) production
sales
13
NH3 1.9 2/month Yes No
Yes No
Yes No
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
Price/
GBq
Price/
GBq
Price/
GBqle
Price/
GBq
Price/
GBq

2005 COUNTRY: UNITED STATES OF AMERICA USA-68
[1] INSTITUTE: Yale University/VAMC West Haven
PET Imaging Center (115A)
950 Campbell Avenue
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OF
West Haven, CT 06516
+1 203 937 4884
garg@biomed.med-yale.edu
Dr. Pradeep Garg
Director, Radiopharmaceutical Chemistry
Negative ion YEAR OF:
CYCLOTRON:
(I) INSTALLATION
1991
MANUFACTURER: CTI, Inc. (II) UPGRADE:
MODEL: RDS 112
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 11 Yes No
Maximum beam available (µA) 40
Typical beam employed (µA) 20-40
[5] CYCLOTRON OPERATION:
Total hours (h)/ week h/week for radionuclide h/week for h/week for
h/week for
production
research
maintenance applications
30-40 ~ 10
[6] CYCLOTRON APPLICATIONS: h/week h/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify):
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No
Mössbauer sources? (specify which & quantity) Yes No
X ray sources? (specify which & quantity) Yes No
Intense neutron beam? (specify average En = ?) Yes No
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
18 18
F- labeled androgens, F- labeled prostate probes
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often? Yale University and
VA Nuclear Medicine: 0-2 times/month
Yes No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No
[11] TYPE OF IMAGING EQUIPMENT AVAILABLE ON-SITE Number
� 511 KeV coincidence
� Gamma camera
� Single photon tomography (SPET)
� Positron emission tomography (PET)
– Clinical 1
– Small animal
– Plant biochemistry
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No
[14] Is the cyclotron used for targetry development? Yes No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes No
[16] Does your institute accept IAEA research fellows for training/experience? Yes No
525
519

18F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
520 526
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18
OH2 (ml)
18
O2 (ml)
18
OH2 (g)
18
O2 (l)
18
OH2?
18 O (p, n) 18 F ~16 >98 0.32 Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG 5 - 6 4 - 10/week Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of
(list)
batch (GBq) production
Ammonia ~1 1-10/month
15 O RADIOPHARMACEUTICALS PRODUCED
Nuclear reaction used Distribution/
sales
16 13
O(p,a) N Yes No
Yes No
Yes No
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction
(list)
used
Water 3-4 0-40/week
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
COMMENTS: (e.g. you may add names of additional labelled compounds/radiopharmaceuticals being produced)
11 C - NNC 112, Dolipram, Tropanes; 18 F Deutero-Altanserine, para fluoro benzylguanidine, Fallypride.
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq

2005 COUNTRY UNITED STATES OF AMERICA USA-69
[1] INSTITUTE: Cyclo-Tech, LLC
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
7650 First Place, Oakwood Village, OH 44146
440-439-5356
mberridge@cyclo-tech.com
440-439-5403
Marc Berridge, Ph.D., President
TITLE/POSITION:
OTHER SENIOR STAFF:
Ken Voelker / VP Cyclotron Engineering
NAME/POSITION
Bonnie Bennington / VP Production
[3] TYPE OF CYCLOTRON: PET-Trace
YEAR OF:
MANUFACTURER: GE
(I) INSTALLATION:
2002
MODEL:
PETtrace
(II) UPGRADE:
N/A
[4] CYCLOTRON CHARACTERISTICS: 17 MeV proton, 8 MeV deuteron, Negative ion
1
H
2
H
3
He
4
He DualBea
Beam energies (MeV) 17 8 na na Yes
Maximum beam available (µA) 60 40
Typical beam employed (µA) 50 20
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week for Hours/week for research Hours/week for Hours/week
radioproduction
maintenance application
25 21 4 8
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: 0 Radiography: 0
Materials science: 0 Proton therapy: 0
Physics: 0 Neutron therapy: 0
Activation analysis: 0 Other (specify)
[7] Is the cyclotron used to produce:
Calibration sources? (specify which & quantity) Yes G No G n
Mössbauer sources? (specify which & quantity) Yes G No G n
X ray sources? (specify which & quantity) Yes G No G n
Intense neutron beam? (specify average En = ?) Yes G No G n
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
I-124, Cu-64
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried out on-
site?
[11] Type of imaging equipment available on-site
511 KeV coincidence
Gamma camera
Positron emission tomography (PET)
Number
–Clinical, Small animal, Plant biochemistry 0.1 (Shared Mobile)
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for agricultural N
applications such as plant biochemistry/research?
[13] Is the cyclotron used for nuclear reaction cross-section measurements? N
[14] Is the cyclotron used for targetry development? Y
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? N
[16] Does your institute accept IAEA research fellows for training/experience?
Y
Y
527
521

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
522 528
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 18
O (p, n) F 2.5 Ci 95 1.3 mL 100g Y
Ne (d, �) 18 F na
16 18
O (�, x) F na
18
F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBqe
18
FDG 50% (uncorr) Y Y na
Fluorocarazolol 40% 1/mo Y Y
fluticasone
propionate
40% 18/mo Y Y
6-FDG 50% 4/mo Y Y etc
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
Topotecan 15% 1/mo Y Y
Nicotine 85% 2/mo Y N
Various Steroids 70% 2/mo Y N
Raclopride 70% 1/mo Y N etc
13
N RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on Frequency of Nuclear reaction used Distribution/ Price/
(list)
batch (GBq) production
sales
GBq
Ammonia 0.8 Ci 20/mo O-16 (p,alpha) Y
Nitrogen 0.8 Ci 1/mo O-16 (p,alpha) N
Yes G No G
15
O RADIOPHARMACEUTICALS PRODUCED
Name
Typical yield on batch (GBq) Frequency of production Nuclear reaction Price/
(list)
used
GBq
Water 0.5 Ci N-14 (d,n)
CO 0.5 Ci
Butanol 0.15 Ci
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes G No G Yes G No G
67
Ga Yes G No G Yes G No G
86
Y Yes G No G Yes G No G
94m
Tc Yes G No G Yes G No G
103
Pd Yes G No G Yes G No G
111
In Yes G No G Yes G No G
123
I
Yes G No G Yes G No G
124
I
Yes G No G Yes G No G
201
Tl Yes G No G Yes G No G
211
At Yes G No G Yes G No G
18 O2 (l)

2005 COUNTRY UNITED STATES OF AMERICA USA-70
[1] INSTITUTE: CYCLOTOPE – Accelerated Medicine
8285 El Rio, Suite 160
TELEPHONE NO.:
E-MAIL ADDRESS:
FAX NO.:
[2] PERSON IN CHARGE:
TITLE/POSITION:
OTHER SENIOR STAFF:
NAME/POSITION
[3] TYPE OFCYCLOTRON:
Houston, TX 77054
(713) 747-5686
fdg@cyclotope.com
(713)747-4858
Carlos Gonzalez
President
Roberto Strangis, Cyclotron Engineer
YEAR OF:
(I) INSTALLATION:
Negative Ion
2002
MANUFACTURER: ACS
MODEL:
TR19/9
(II) UPGRADE:
[4] CYCLOTRON CHARACTERISTICS:
1
H
2
H
3
He
4
He Dual Beams
Beam energies (MeV) 18 9 Yes X No
Maximum beam available (µA) 350 50
Typical beam employed (µA) 100 40
[5] CYCLOTRON OPERATION:
Total hours/ week Hours/week for Hours/week for research Hours/week for Hours/week for
radioproduction
maintenance applications
[6] CYCLOTRON APPLICATIONS: Hours/week Hours/week
Radiobiology: Radiography:
Materials science: Proton therapy:
Physics: Neutron therapy:
Activation analysis: Other (specify)
[7] IS THE CYCLOTRON USED TO PRODUCE:
Calibration sources? (specify which & quantity) Yes No X
Mössbauer sources? (specify which & quantity) Yes No X
X ray sources? (specify which & quantity) Yes No X
Intense neutron beam? (specify average En = ?) Yes No X
[8] Radionuclides and radiopharmaceuticals planned to be produced in the next 1-3 years (specify):
[9] Do you supply radionuclides to other institutions?
If yes and available, name of institution/s & how often?
Yes X No
[10] Are clinical studies and/or medical research using cyclotron radiopharmaceuticals carried
out on-site?
Yes No X
[11] Type of imaging equipment available on-site
511 KeV coincidence
Gamma camera
Single photon tomography (SPET)
Positron emission tomography (PET)
– Clinical
– Small animal
– Plant biochemistry
Number of
[12] Are cyclotron radionuclides/labelled compounds used or planned to be used for
agricultural applications such as plant biochemistry/research?
Yes No X
[13] Is the cyclotron used for nuclear reaction cross-section measurements? Yes No X
[14] Is the cyclotron used for targetry development? Yes X No
[15] Is the cyclotron used for education and training in nuclear sciences, health physics, etc.? Yes X No
[16] Does your institute accept IAEA research fellows for training/experience? Yes X No
529
523

18 F RADIONUCLIDE PRODUCTION
Production Typical
production
yield (GBq)
524 530
% Isotopic
enrichment
18 O used
Target Volume Usage/year Do you
recycle
18 OH2?
18 OH2
18 O2
18 OH2 (g)
18 O2 (l)
18 O (p, n) 18 F Yes
No
Ne (d, α) 18 F
16 O (α, x) 18 F
18 F RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
18
FDG Daily Yes No X Yes X No
Yes No Yes No
Yes No Yes No
Yes No Yes No
11
C RADIOPHARMACEUTICALS PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/
(list)
(GBq)
production
sales
Yes No Yes No
Yes No Yes No
Yes No Yes No
Yes No Yes No
13 N RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Typical yield on
batch (GBq)
15 O RADIOPHARMACEUTICALS PRODUCED
Name
(list)
Frequency of
production
Nuclear reaction used Distribution/
sales
Yes No
Yes No
Yes No
Typical yield on batch (GBq) Frequency of production Nuclear reaction
used
Price/
GBq
Price/
GBq
Price/
GBq
Price/
GBq
OTHER ISOTOPES PRODUCED
Name
Yield on batch Frequency of Used on site Distribution/ Price/
(list)
(GBq)
production
sales
GBq
64
Cu Yes No Yes No
67
Ga Yes No Yes No
86
Y Yes No Yes No
94m
Tc Yes No Yes No
103
Pd Yes No Yes No
111
In Yes No Yes No
123
I
Yes No Yes No
124
I
Yes No Yes No
201
Tl Yes No Yes No
211
At Yes No Yes No
[17] COMMENTS: (e.g., you may add names of additional labelled compounds/radiopharmaceuticals being produced)

531

532
02-31581