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Table of contents - Johns Hopkins Medical Institutions

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2:6 MEDICATION<br />

ANTIEMETICS<br />

Patient Information Sheet<br />

DRUGS:<br />

• Ondansetron (Z<strong>of</strong>ran)<br />

• Granisetron (Kytril)<br />

• Dolasetron (Anzemet)<br />

These are the most commonly used drugs. They usually control nausea well and cause few<br />

side effects. These drugs can be given by vein or by mouth. If you are taking one <strong>of</strong> these<br />

drugs at home, your doctor will tell you exactly how much to take and how <strong>of</strong>ten to take it.<br />

In some cases other drugs may be added to try to control nausea:<br />

• Prochloraperazine (Compazine)<br />

• Dexamethasone (Decadron)<br />

• Lorazepam (Ativan)<br />

PURPOSE: Antiemetics are medications given to reduce nausea and vomiting caused by<br />

chemotherapy. There are several different types <strong>of</strong> drugs that may be used. Sometimes different<br />

drugs will be combined to try to achieve the best result.<br />

SIDE EFFECTS: Call your doctor right away if you have any <strong>of</strong> these side effects:<br />

• Allergic reaction: Itching or hives, swelling in face or hands, swelling or tingling in<br />

the mouth or throat, tightness in chest, trouble breathing<br />

• Inability to move eyes; other muscle spasms, especially <strong>of</strong> the face, neck or back<br />

Tell your doctor if you experience any <strong>of</strong> these less-serious side effects:<br />

• Constipation, diarrhea or abdominal pain<br />

• Headache<br />

• Dizziness, drowsiness, tiredness or sedation<br />

• Blurred vision<br />

• Fever, chills<br />

• Fatigue

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