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Table of contents - Johns Hopkins Medical Institutions

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2:8 MEDICATION<br />

POSSIBLE SIDE EFFECTS: Some possible side effects are:<br />

• Nausea<br />

• Vomiting<br />

• Headache<br />

• Tiredness<br />

• Constipation<br />

• Low blood count<br />

Other side effects include:<br />

• Weakness<br />

• Memory loss<br />

• Drowsiness<br />

• Back pain<br />

• Fever<br />

• Diarrhea<br />

• Itching<br />

• Dizziness<br />

• Swelling in arms or legs<br />

• Tingling or burning feeling<br />

• Stomach pain<br />

• Loss <strong>of</strong> appetite<br />

• Anxiety<br />

If you experience any <strong>of</strong> the following symptoms, call your doctor immediately:<br />

• Unusual bleeding or bruising<br />

• Rash<br />

• Itching<br />

• Difficulty breathing or swallowing<br />

• Seizures<br />

• Infection<br />

• Your temperature goes above 38ºC (100.5ºF)<br />

• You suddenly feel unwell (even with a normal temperature)<br />

IMPORTANT INFORMATION:<br />

• You should not take Temodar if you have had an allergic reaction to dacarbazine,<br />

another drug used to treat cancer, because you may have a similar reaction while taking<br />

Temodar.<br />

• Temodar can cause a decrease in the bone marrow’s ability to make cells (myelosuppression).<br />

The bone marrow is needed to form several components <strong>of</strong> the blood. Your<br />

doctor will check you for this condition while you are being treated with Temodar.<br />

• If you have a history <strong>of</strong> severe liver or kidney problems your doctor will evaluate and<br />

decide if Temodar is right for you.<br />

• Because Temodar can cause birth defects, women should avoid becoming pregnant,<br />

and stop breast-feeding a baby and nursing while taking Temodar. Tell your healthcare<br />

provider if you are already pregnant or are breast-feeding. Men and women taking<br />

Temodar should use effective birth control.<br />

• Keep this medicine away from children and pets.

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