SNA et rÃ©gulation cardio-vasculaire au cours du sommeil - SPLF

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Mechanisms of Sympathetic Activationin Obesity• Direct effect of insulin on hypothalamus stimulatingsympathetic nervous systemRowe Diabetes 1981• High serum Leptin level increases renal and inf. limbvasculature sympathetic outflowHaynes J Clin Invest 1997• Angiotensinogen production in (central) adipocytesGiacchetta Int J Obese 2000
Sympathetic nervous system activity inobesity• SNA under-activity in obese may providemetabolic basis for obesityBray GA, Vitam Horm 1989• SNA hyperactivity in obese occurring withchronic overeating may facilitate weight balanceLandsberg L, Q J Med 1986
Page 1: SNA et régulation cardio-vasculair
Page 4 and 5: Le sommeil normalEEGEOGEMGVeilleSom
Page 9 and 10: Bases de compréhension contrôle c
Page 11 and 12: Système Nerveux AutonomeMéthodes
Page 13 and 14: L’activité parasympathique augme
Page 15 and 16: Fonction cardiovasculaire au cours
Page 17 and 18: Fonction cardiovasculaire au cours
Page 19 and 20: Microneurographie :Somers et al, NE
Page 21 and 22: Sommeil et activité adrénergiqueI
Page 23 and 24: Baroréflexe et sommeilR. HornerLun
Page 25 and 26: Les deux pics de survenue desaccide
Page 27 and 28: Privation de sommeil et activité a
Page 29 and 30: Réponse hiérarchique d’éveil :
Page 31 and 32: Bases de compréhension du contrôl
Page 33 and 34: Implications physiopathologiques :
Page 35 and 36: Fragmented sleep and ANS activitySo
Page 37 and 38: Système Nerveux Autonome etSyndrom
Page 39 and 40: CPAPWithdrawalSomers et al, J Clin
Page 41 and 42: Adrenergic tone reductionunder nasa
Page 43 and 44: Kara et al. Acta Physiol Scand 2003
Page 49: Effets chroniques du SAS• Hyperac
Page 53 and 54: MSNA reflex abnormalities in patien
Page 57 and 58: Système Nerveux Autonome etHypoxie
Page 59 and 60: Réactivité vasculaireMicro-éveil
Page 61 and 62: Vascular reactivity in rats, HI vs
Page 63 and 64: Infarct size
Page 65 and 66: LumenCytosolNucleusVSMCCyclic axial
Page 67 and 68: Intravital microscopy (mesenteric a
Page 69 and 70: IH and early atherosclerosisP = 0,0
Page 71 and 72: On-going studies in rodentsexposed

SNA et rÃ©gulation cardio-vasculaire au cours du sommeil - SPLF

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