SNA et rÃ©gulation cardio-vasculaire au cours du sommeil - SPLF

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IH and early atherosclerosis180160140P = 0,011P = 0,022P = 0,043120Proliferation(% of control value)100806040200NIHDay 5IHDay 14IHDay 35Arn<strong>au</strong>d C <strong>et</strong> al AJRCCM, 2006 submitted
On-going studies in rodentsexposed to IHSpontaneously hypertensive ratsPressive response ++ to IHInfarct size much increasedApo E miceApoE mice rapidlyrecruit blood monocytesinto the sub-endothelial space,accumulating lipids andbecoming foam cells.Comparison with continuous hypoxia,sleep deprivation and sleep fragmentation
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SNA et régulation cardio-vasculair
Page 4 and 5:
Le sommeil normalEEGEOGEMGVeilleSom
Page 9 and 10:
Bases de compréhension contrôle c
Page 11 and 12:
Système Nerveux AutonomeMéthodes
Page 13 and 14:
L’activité parasympathique augme
Page 15 and 16:
Fonction cardiovasculaire au cours
Page 17 and 18:
Fonction cardiovasculaire au cours
Page 19 and 20: Microneurographie :Somers et al, NE
Page 21 and 22: Sommeil et activité adrénergiqueI
Page 23 and 24: Baroréflexe et sommeilR. HornerLun
Page 25 and 26: Les deux pics de survenue desaccide
Page 27 and 28: Privation de sommeil et activité a
Page 29 and 30: Réponse hiérarchique d’éveil :
Page 31 and 32: Bases de compréhension du contrôl
Page 33 and 34: Implications physiopathologiques :
Page 35 and 36: Fragmented sleep and ANS activitySo
Page 37 and 38: Système Nerveux Autonome etSyndrom
Page 39 and 40: CPAPWithdrawalSomers et al, J Clin
Page 41 and 42: Adrenergic tone reductionunder nasa
Page 43 and 44: Kara et al. Acta Physiol Scand 2003
Page 49 and 50: Effets chroniques du SAS• Hyperac
Page 51 and 52: Sympathetic nervous system activity
Page 53 and 54: MSNA reflex abnormalities in patien
Page 57 and 58: Système Nerveux Autonome etHypoxie
Page 59 and 60: Réactivité vasculaireMicro-éveil
Page 61 and 62: Vascular reactivity in rats, HI vs
Page 63 and 64: Infarct size
Page 65 and 66: LumenCytosolNucleusVSMCCyclic axial
Page 67 and 68: Intravital microscopy (mesenteric a
Page 69: IH and early atherosclerosisP = 0,0
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SNA et rÃ©gulation cardio-vasculaire au cours du sommeil - SPLF

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