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Gen specie boala Faza de evolutie Infectiv /nu ... - Cursuri Medicina

Gen specie boala Faza de evolutie Infectiv /nu ... - Cursuri Medicina

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Trypanosoma<br />

-brucei gambiese<br />

Tripanosomiaza<br />

africana= <strong>boala</strong><br />

som<strong>nu</strong>lui vest si centru<br />

-brucei rho<strong>de</strong>siense<br />

Tripanosomiaza<br />

africana= <strong>boala</strong><br />

som<strong>nu</strong>lui est si sud<br />

-cruzi<br />

Tripanosomiaza<br />

americana= <strong>boala</strong><br />

Chagas<br />

-amastigoti<br />

-promastigoti<br />

-epimastigiti<br />

-trypomastogoti slen<strong>de</strong>r<br />

produce <strong>boala</strong> si se<br />

multiplica!!! Dar stumpy<br />

este esential pentru<br />

transmitere la vector<br />

!!!sferomastigotii trec<br />

bariera hematoencefalica<br />

-amastigoti<br />

-promastigoti<br />

-epimastigiti<br />

-trypomastogoti -slen<strong>de</strong>r<br />

produce <strong>boala</strong> si se<br />

multiplica!!! Dar stumpy<br />

este esential pentru<br />

transmitere la vector<br />

!!!sferomastigotii trec<br />

bariera hematoencefalica<br />

-amastigoti/pseudochist in<br />

tesuturi<br />

-trypomastogoti<br />

Toxoplasma gondii -tahizoit<br />

-bradizoit: -chist tisular<br />

-oochist – imatur,<br />

sporuleaza in 5 zile – matur<br />

(8 sporozoiti)<br />

+<br />

Inoculativvectorialatrypanom(ulce<br />

ratie pruriginoasa-cu<br />

cicatrice la vin<strong>de</strong>care)<br />

-Sem<strong>nu</strong>l winterottom<br />

-sem<strong>nu</strong>l<br />

keran<strong>de</strong>l=hiperestezii<br />

-evol lenta<br />

Inoculativvectorialatrypanom(ulce<br />

ratie pruriginoasa-cu<br />

cicatrice la vin<strong>de</strong>care)<br />

-Sem<strong>nu</strong>l winterottom<br />

-sem<strong>nu</strong>l<br />

keran<strong>de</strong>l=hiperestezii<br />

-evol rapida<br />

contaminativavectorialachagoma/Sem<br />

<strong>nu</strong>l romana-e<strong>de</strong>m<br />

palpebral unilateral—fv lla<br />

copii<br />

Digestiva<br />

Transplacentar<br />

Musca tze-tze-hematoga<br />

Musca tze-tze-hematoga<br />

Reduviid—hematofag,<br />

dar lasa <strong>de</strong>jectele, care<br />

sunt<br />

pruriginoaseconjuncti<br />

vita<br />

-sange-hemoflagelat<br />

polimorfi<br />

!!!poate suferi variatie<br />

antigenicaepuizare SI<br />

-febra neregulata si<br />

cefalee<br />

-modif ritm somn<br />

veghe<br />

-ob<strong>nu</strong>bilare coma<br />

<strong>de</strong>ces<br />

-sange-hemoflagelat<br />

polimorfi<br />

!!!poate suferi variatie<br />

antigenicaepuizare SI<br />

-febra neregulata si<br />

cefalee<br />

-modif ritm somn<br />

veghe<br />

-ob<strong>nu</strong>bilare coma<br />

<strong>de</strong>ces<br />

-f acuta cu fb, rash,<br />

miocardita.<br />

-f cronica<br />

megaorgnestica<br />

inervatia autonoma a<br />

m nete<strong>de</strong>/miocardice<br />

Creier<br />

Sit limfatic<br />

Boala abortiva si<br />

mafolmativa<br />

*id promastigoti pe med<br />

<strong>de</strong> cultura NNN<br />

*imuno ac si ag specifice<br />

*morf pe frotiu sau<br />

picatura groasa<br />

*biopsie ggl<br />

*IF<br />

*celula Mott pe necropsii<br />

cerebrale<br />

*morf pe frotiu sau<br />

picatura groasa<br />

*biopsie ggl<br />

*IF<br />

*celula Mott pe necropsii<br />

cerebrale<br />

*morf direct sau<br />

frotiutrypomastigoti<br />

monomorfi<br />

*necropsii ale<br />

pseudoochisturilor<br />

*xenodiagnostic<br />

*morfologic:<br />

-t p pe biopsi sre/la/lcr;<br />

frotiu; inocul la animal<br />

-b/ct necropsi musculare<br />

sau cerebrale<br />

*imuno<br />

*imag

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