N. Bresolin - E. Medea

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Expression of muscle markers by CD133 positive cells derived from the blood tissues. AC133+ MyHC GFP Merge
Double-blinded randomized clinical trial phase I: autologous transplantation of muscle-derived AC133+ cells in Duchenne Muscular Dystrophy. Eight DMD patients were included in this study and randomized into two groups: Group A (n=5; subjects 003-004-005-006-007) AC133+cells injection into left abductor digiti minimi muscles (ADM) Group B (n=3 subjects 008-009-010) saline solution injection into ADM Primary outcome: Tolerance and feasibility of intramuscular transplantation of AC133+ cells to always ensure first, the patient’s safety and well-being, while aiming towards a treatment. Secondary outcome: muscular strength tests by MVIC and muscle force analysis skinned myofibers. Torrente Y et al. Cell Transplantation 2007
Page 1 and 2: L’impiego delle cellule staminali
Page 3 and 4: Cellule staminali • Capacità di
Page 5: Blood blood cells Vessels endotheli
Page 8: In vitro differentiation of iPS. In
Page 11 and 12: SVZ Isolation Astrocytes SVZ MATURE
Page 13 and 14: Multipotentiali Multipotentiality,
Page 15 and 16: Il trapianto di cellule staminali L
Page 17 and 18: Distrofia Muscolare di Duchenne E
Page 19 and 20: Il nostro obiettivo: trapiantare le
Page 21 and 22: Muscle homing of the Sca-1+/CD34-MD
Page 23 and 24: Myogenic differentiation of Sca-1+/
Page 25: TRAP assay Clonogenic, self-renewal
Page 29 and 30: Local side effects after intramuscu
Page 31 and 32: Intra-arterial delivery of wild-typ
Page 33 and 34: Expression of α-SG and dystrophin
Page 35 and 36: Three-dimensional visualization of
Page 37 and 38: Lentivirus U7exon51 map : Promoteur
Page 39: Human dystrophin expression in scid
Page 43 and 44: Sclerosi Laterale Amiotrofica
Page 45 and 46: LeX+CX+ cells share the properties
Page 47 and 48: Time to fall (s) 250 200 150 100 50
Page 49 and 50: Il trapianto di cellule LeX+CXCR4+
Page 51 and 52: Cellule staminali nelle malattie de
Page 53 and 54: Atrofia Muscolare Spinale (SMA) SMN
Page 56: Neuroni ALDH proiettano lunghi asso
Page 60 and 61: GFP/Nestina Predifferenziamento GFP
Page 62 and 63: Midollo spinale di topo trapiantato
Page 64 and 65: Effetti del trapianto sui motoneuro
Page 66 and 67: Utilizzo di sostanze per promuovere
Page 68: Stem Cell Research Institute DIBIT-

N. Bresolin - E. Medea

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