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T.Mazzei, A.Novelli pdf - Sipps

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Cefuroxime<br />

Prophylaxis with brand versus generic drugs, incidence of<br />

postoperative infections after coronary surgery<br />

Postoperative infections<br />

Branded CFX<br />

(n=313)<br />

Generic CFX<br />

(n=305)<br />

n % n %<br />

p value<br />

Surgical site infections 6 1.9 31 10.1 < 0.0001<br />

Bacteremia 2 0.6 8 2.6 0.10<br />

Septic shock 0 0 6 2.0 0.04<br />

Total postoperative infections 8 2.5 39 12.8 < 0.001<br />

p < 0.05 statistically significant<br />

Mastoraki E et al., J Infect, 2008

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