T.Mazzei, A.Novelli pdf - Sipps
T.Mazzei, A.Novelli pdf - Sipps
T.Mazzei, A.Novelli pdf - Sipps
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Cefuroxime<br />
Prophylaxis with brand versus generic drugs, incidence of<br />
postoperative infections after coronary surgery<br />
Postoperative infections<br />
Branded CFX<br />
(n=313)<br />
Generic CFX<br />
(n=305)<br />
n % n %<br />
p value<br />
Surgical site infections 6 1.9 31 10.1 < 0.0001<br />
Bacteremia 2 0.6 8 2.6 0.10<br />
Septic shock 0 0 6 2.0 0.04<br />
Total postoperative infections 8 2.5 39 12.8 < 0.001<br />
p < 0.05 statistically significant<br />
Mastoraki E et al., J Infect, 2008