Working Paper of Public Health Volume 2012 - Azienda Ospedaliera ...

Azienda Ospedaliera Nazionale“SS. Antonio e Biagio e Cesare Arrigo”Working Paper of Public Healthnr. 12/2012Title: OSTEONECROSIS OF JAW (ONJ): IMPACT OF ITALIAN PATIENTS, ANDROLE OF ITALIAN PHYSICIANS, DENTISTS, AND RESEARCHERS IN THEGROWING EVIDENCE OF A “NEW” DISEASEAuthors: Fusco V.; 1 * Baraldi A.; 2 Fasciolo A.; 3 Rapetti M.; 4 De Martino I.; 3 Randi L.; 3Bedogni A.; 5 Agrillo A.; 6 Campisi G.; 7Type: Original ArticleKeywords: Osteonecrosis of jaw;AbstractPurpose: Osteonecrosis of jaw (ONJ) is an uncommon but severe complication observedmostly in patients treated with bisphosphonates (BPs) for bone metastases,myeloma, osteoporosis (so called BRONJ, Bisphosphonate-Related Osteonecrosisof Jaw), but also with other drugs (bevacizumab, sunitinib, denosumab). Thenumber of cases observed in Italy appears high in comparison with other countriesand we present a review of several aspects of ONJ in Italy and the role of Italianhealth professionals and researchers on increasing knowledge and adequatereporting of ONJ phenomenon;1 Unit of Oncology, Department of Oncology and Haematology,* Corresponding author: vfusco@ospedale.al.it;2Unit of Haematology, Department of Oncology and Haematology,3 Unit of Maxillo-Facial Surgery;4Centro Documentazione e Prevenzione Osteonecrosi,Azienda Ospedaliera di Alessandria (City Hospital), Alessandria, Italy5 Section of Oral and Maxillofacial Surgery, Department of Surgery,Azienda Ospedaliera Universitaria Integrata, Verona, Italy6 Section of Maxillofacial Surgery, Department of Odontostomatologic Sciences,University "La Sapienza", Rome, Italy7 Sector of Oral Medicine “V.Margiotta”, Department of Surgical and Oncological Sciences,University of Palermo, Palermo, Italy1