19.04.2013 Views

A atividade antigonadotrófica das progestinas (derivados da ... - Merck

A atividade antigonadotrófica das progestinas (derivados da ... - Merck

A atividade antigonadotrófica das progestinas (derivados da ... - Merck

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

8. Viot G, Thévenot R, Paris J, Milano G, Hopkins R. 1985 Etude de la<br />

pharmacocinétique d´un progestatif à l´aide du produit marqué au 14<br />

C ou par méthode froide. J Pharmacol Clin. 4:127-136.<br />

9. Botella J, Paris J, Duc I, Lalhou B. 1988 Nomegestrol acetate binding<br />

to cytosolic progesterone receptor in human endometrium. Med Sci<br />

Res. 16:299-300.<br />

10. Botella J, Duc I, Delansorne R, Paris J, Lahlou B. 1990 Structure-activity<br />

and structure-affinity relationships of 19-nor-progesterone<br />

derivatives in rat uterus. J Endocrinol Invest. 13:905-910.<br />

11. Ojasoo T, Raynaud JP. 1983 Receptor binding profiles of progestins.<br />

In: Jasonni VM, Nenci I, Flamigni C, eds. Steroids and endometrial<br />

cancer. New York: Raven Press; 11-28.<br />

12. Basdevant A, Pelissier C, Conard J, Degrelle, Guyene TT, Thomas JL.<br />

1991 Effects of nomegestrol acetate (5 mg/<strong>da</strong>y) on hormonal, metabolic<br />

and hemostatic parameters in premenopausal women. Contraception.<br />

44:599-605.<br />

13. Friedewald WT, Levy RI, Fredrickson DS. 1972 Estimation of the<br />

concentration of low-density lipoprotein cholesterol in plasma without<br />

the use of the preparative centrifuge. Clin Chem. 181:499-502.<br />

14. Couzinet B, Young J, Brailly S, Chanson P, Schaison G. 1995. Even after<br />

priming with ovarian steroids of pulsatile gonadotropin-releasing<br />

hormone administration, naltrexone is unable to induce ovulation in<br />

women with functional hypothalamic amenorrhea. J Clin Endocrinol<br />

Metab. 80:2102-2107.<br />

15. Thomas G, Plu G, Thalabard JC. 1992 Identification of pulses in hormone<br />

time series using outlier detection methods. Stat Med.<br />

11:2133-2145.<br />

16. Markiewicz L, Hochberg RB, Gurpide E. 1992 Intrinsic estrogenicity<br />

of some progestagenic drugs. J Steroid Biochem Mol Biol. 41:53-58.<br />

17. Botella J, Duranti E, Viader V, Duc I, Delansorne R, Paris J. 1995<br />

Lack of estrogenic potential of progesterone – or 19-nor-progesterone-derived<br />

progestins as opposed to testosterone – or<br />

19-nor-testosterone derivatives on endometrial Ishikawa cells. J Steroid<br />

Biochem Mol Biol. 55:77-84.<br />

18. Barbieri RL, Petro Z, Canick JA, Ryan KJ. 1983 Aromatization of norethindrone<br />

to ethinyl estradiol by human placental microsomes. J<br />

Clin Endocrinol Metab. 57:299-303.<br />

19. Catherino WH, Jor<strong>da</strong>n VC. 1995 Nomegestrol acetate, a clinically<br />

useful 19-norprogesterone derivative which lacks estrogenic activity.<br />

J Steroid Biochem Mol Biol. 55:239-246.<br />

20. Mac Lusky NJ, McEwen BS. 1980 Progestin receptors in rat brain:<br />

distribution and properties of cytoplasmic progestin binding sites.<br />

Endocrinology. 106:192-202.<br />

21. Knobil E, Hotchkiss J. 1994 The menstrual cycle and its neuroendocrine<br />

control. In: Knobil E, Neill J, eds. The physiology of reproduction.<br />

New York: Raven Press; 711-749.<br />

22. Couzinet B, Le Strat N, Brailly S, Schaison G. 1986 Comparative effects<br />

of cyproterone acetate or a long-acting gonadotropin releasing<br />

hormone agonist in polycystic ovarian disease. J Clin Endocrinol Metab.<br />

63:1031-1035.<br />

23. Couzinet B, Thomas G, Thalabard JC, Brailly S, Schaison G. 1989<br />

Effects of a pure antiandrogen on gonadotropin secretion in normal<br />

women and in polycystic ovarian disease. Fertil Steril. 52:42-50.<br />

24. Couzinet B, Pholsena M, Young J, Schaison G. 1993 The impact of a<br />

pure anti-androgen (flutamide) on LH, FSH, androgens and clinical<br />

status in idiopathic hirsutism. Clin Endocrinol (Oxf). 39:157-162.<br />

25. Gravanis A, Schaison G, George M, et al. 1985 Endometrial and pituitary<br />

responses to the steroi<strong>da</strong>l antiprogestin RU 486 in postmenopausal<br />

women. J Clin Endocrinol Metab. 60:156-163.<br />

26. Tikkanen MJ, Nikkilä EA, Kuusi T, Sipinen S. 1982 High density lipoprotein-2<br />

and hepatic lipase: reciprocal changes produced by estrogen<br />

and norgestrel. J Clin Endocrinol Metab. 54:1113-1117.<br />

27. Dorangeon P, Thomas JL, Gillery P, Lumbroso M, Hazard MC. 1992<br />

Short term effects on lipids and lipoproteins of two progestogens used<br />

in post-menopausal replacement therapy. Eur J Clin Res. 3;187-193.<br />

28. Lobo R. 1991 Clinical review 27: effects of hormonal replacement on<br />

lipids and lipoproteins in postmenopausal women. J Clin Endocrinol<br />

Metab. 73:925-930.<br />

29. Salehian B, Wang C, Alexander G, et al. 1995 Pharmacokinetics, bioefficacy,<br />

and safety of sublingual testosterone cyclodextrin in hypogona<strong>da</strong>l<br />

men: comparison to testosterone enanthate - a clinical research<br />

center study. J Clin Endocrinol Metab. 80:3567-3575.<br />

30. Dorangeon P, Thomas JL, Choisy H, Lumbroso M, Hazard MC. 1993<br />

Effects of nomegestrol acetate on carbohydrate metabolism. Diabète<br />

Metab. 19:441-445.<br />

31. Conard J, Basdevant A, Thomas JL, et al. 1995 Cardiovascular risk<br />

factors and combined estrogen-progestin replacement therapy: a placebo-controlled<br />

study with nomegestrol acetate and<br />

10 – A <strong>ativi<strong>da</strong>de</strong> <strong>antigonadotrófica</strong> <strong><strong>da</strong>s</strong> <strong>progestinas</strong> (<strong>derivados</strong> <strong>da</strong> 19-nortestosterona e <strong>da</strong> 19-norprogesterona) não é media<strong>da</strong> pelo receptor de androgênio

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!