Cursul 19-Profilaxia bolilor genetice
Cursul 19-Profilaxia bolilor genetice
Cursul 19-Profilaxia bolilor genetice
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Alegerea testului in functie de rata de<br />
detectie (sensibilitatea)<br />
Trimester Screening Test Detection Rate<br />
1 st NT measurement 64-70%<br />
NT + PAPP-A, bhCG 82-87%<br />
2 nd Triple test 69%<br />
Quadruple test 81%<br />
1 st & 2 nd NT, PAPP-A, Quad test 94-96%<br />
PAPP-A quad test 85-88%<br />
Stepwise sequential<br />
(If 1 st test +, offer 2 nd ; & if 1 st test -, offer<br />
2 nd anyway)<br />
Contingent sequential<br />
(If 1 st test +, offer 2 nd ; if 1 st test –, stop)<br />
95%<br />
88-94%