Prof. Dr. med. Jens Waschke - Universität Würzburg

Waschke J, Drenckhahn D, Adamson RH, Barth H, Curry FE (2004) cAMP protectsendothelial barrier functions by preventing Rac-1 inhibition. Am. J. Physiol. Heart Circ.Physiol., 287: H2427-433Waschke J, Bruggeman P, Baumgartner W, Zillikens D, Drenckhahn D (2005) Pemphigusfoliaceus IgG cause dissociation of desmoglein 1-containing junctions without blockingdesmoglein 1 transinteraction. J. Clin. Invest., 115(11):3157-65Waschke J, Spindler V, Bruggeman P, Zillikens D, Schmidt G, Drenckhahn D (2006)Inhibition of Rho A activity causes pemphigus skin blistering. J. Cell Biol., 175(5): 721-7Spindler V, Drenckhahn D, Zillikens D, Waschke J (2007) Pemphigus IgG causes skinsplitting in the presence of both desmoglein 1 and desmoglein 3. Am. J. Pathol., 171(3): 906-916Heupel WMH, Zillikens D, Drenckhahn D, Waschke J (2008) Pemphigus vulgaris IgGdirectly inhibit desmoglein 3-mediated transinteraction. J. Immunol., 181(3):1825-1834Heupel WMH, Engerer P, Schmidt E, Waschke J (2009) Pemphigus vulgaris IgG cause lossof desmoglein-mediated adhesion and keratinocyte dissociation independent of epidermalgrowth factor receptor. Am. J. Pathol., 174(2): 475-485Heupel WM, Müller T, Efthymiadis A, Schmidt E, Drenckhahn D, Waschke J (2009) Peptidestargeting the desmoglein 3 adhesive interface prevent autoantibody-induced acantholysis inpemphigus. J. Biol. Chem., 284(13): 8989-8995*Heupel WM, Efthymiadis A, Müller T, Schlegel N, Baumer Y, Baumgartner W, DrenckhahnD, Waschke J (2009) Endothelial barrier stabilization via a cyclic peptide targeting VEcadherintransinteraction. J. Cell Sci., im Druck*Schlegel N, Baumer Y, Drenckhahn D, Waschke J (2009) LPS-induced endothelial barrierbreakdown is cAMP-dependent in vivo and in vitro. Crit. Care Med., im DruckInsgesamt 32 Originalarbeiten, 2 Reviews, 1 Lehrbuch (Herausgeber)