Präsentation Prof. Klingberg

Sicherheit
most negative change during the treatment
phase in patients with increase of symptoms
CBT 1 CR 2
nCBT/nCR Maximal change
compared to
baseline
Mean (Std.
Dev.)
Effect size of
change
(95% CI)
PANSS 4 MNS 5 64/58 -0.56 9 (0.56) -0.66 (-1.02 to -
0.31)
PANSS 4
Positive
68/66 -0.55 (0.46) -0.67 (-1.02 to -
0.32)
SANS 6 total 69/66 -0.47 (0.36) -0.78 (-1.13 to -
0.44)
CDSS 7 69/53 -0.43 (0.33) -1.03 (-1.38 to -
0.67)
Maximal
change
compared to
baseline
(Mean, Std.
Dev.)
Effect size of
change
(95% CI)
-0.61 (0.47) -0.77 (-1.15 to -
0.40)
-0.61 (0.54) -0.57 (-0.91 to -
0.22)
-0.50 (0.46) -0.83 (-1.19 to -
0.47)
-0.41 (0.28) -0.91 (-1.31 to -
0.51)
Effect Size
CBT-CR
(95% CI)
0.09 (-0.27 to
0.44)
0.11 (-0.23 to
0.45)
0.06 (-0.27 to
0.40)
-.05 (-0.41 to
0.31)
GAF 8 54/55 9.06 (7.26) 0.85 (0.45 to 1.24) 9.65 (7.30) 1.06 (0.66 to 1.46) -.08 (-0.46 to
0.29)
Prof. Dr. Klingberg
p
for max.
increase 3
1 Cognitive Behavioural Therapy, 2 Cognitive Remediation, 3 Analysis of Covariance adjusted for Baseline, 4 Positive and Negative Syndrom
Scale, 5 Modified Negative Syndrome, 6 Scale for the Assessment of Negative Symptoms, 7 Calgary Depression Rating Scale, 8 Global
Assessment of Functioning 9 negative values indicate increase in symptom severity
Klingberg et al. (2012) J Nerv Ment Dis
0.748
0.546
0.715
0.717
0.583
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