Jahresbericht 2002/2003 - DRST

Instructions for reporting data to the EBMT Activity Survey 2002
Table 1 (main table)
• Enter the number of patients receiving their first transplant only, performed in 2002 and
not the number of transplants: One patient = one transplant.
• Non-id = any family member (matched or mismatched) other than HLA-identical sibling or
twin.
• Combined allogeneic BM + PBSC transplants should be entered as PBSC.
Tables 1 and 4
Cord blood transplants should be entered in table 1 individually as with other first transplants,
under the heading ‘PBSC’. In addition, enter the total number of cord blood transplants
(allogeneic and autologous separately) in table 4 under the heading ‘General information'.
Tables 1 and 4
Reduced intensity conditioning RIC (former mini-allo, non-myeloablative) transplants should
be entered in table 1 individually as with other first transplant patients. In addition, enter
the total number of RIC allos/autos performed in 2002 in table 4 under ‘General information’.
As there is no official definition of RIC transplants yet, we suggest the following working
proposal to be used, please try and stick to these definitions for the survey 2002.
Only regimens with dosages below these listed should be classified as RIC
• TBI based < 800 cGy TBI fractionated OR
< 400 cGy TBI single dose
AND (if additional chemotherapy is given)
< 60 mg/kg Cyclophosphamide
< 8 mg/kg Busulphan
< 100 mg/kg Thiotepa
< 80 mg/m² Melphalan
• Combination chemotherapy based < 8 mg/kg Bu and Cy < 100 mg/kg
< 80 mg/m² Melphalan
< 200 mg/kg Thiotepa
• Aplastic Anaemia < 100 mg/kg Cyclophosphamide
• Congenital Disease < 8 mg/kg Bu and Cy < 100 mg/kg
• ATG and Fludarabine in any RIC can be classified as RIC
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