(Microsoft PowerPoint - Prävention von Frühaborten.ppt)

Review: The changing role of progesterone in
preterm labour.
Di Renzo GC, Rosati A, Mattei A, Gojnic M, Gerli S.
BJOG. 2005 Mar;112 Suppl 1:57-60
“Progesterone is efficacious when continuation of
pregnancy is hampered by immunological factors, luteinic
and neuroendocrine deficiencies and myometrial
hypercontractility. This may explain the reduction in the
incidence of preterm birth in high risk pregnant women
using high-dosage prophylactic progesterone“
(250mg 17α-hydroxyprogesterone caproat/week 16-20 weeks of
gestation)