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Abstract Proceedings EROC 2011 - New York Osteopathic Medical ...

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<strong>EROC</strong> <strong>2011</strong> <strong>Abstract</strong> <strong>Proceedings</strong> – March 4, <strong>2011</strong><br />

Dept. of Emergency Medicine, Good Samaritan Hospital <strong>Medical</strong> Center, West Islip, NY<br />

Title: Dying to Lose Weight: A Case of Myocardial Infarction Associated with an Over-the-<br />

Counter Weight Loss Supplement<br />

Authors: Laura Fil DO, Eric Decena MD, Rikesh Patel MD, David Levy DO<br />

Emergency Medicine Residency Program, Good Samaritan Hospital <strong>Medical</strong> Center, West Islip, NY<br />

Introduction: We discuss a case of young male who presented to the Emergency Department with<br />

an acute myocardial infarction. An over-the-counter weight loss supplement may have contributed<br />

to his acute event secondary to an undeclared ingredient in the product.<br />

Case description: A 34 year old Hispanic male with no previous medical history presented to the<br />

Emergency Department with chest pressure for three hours. The pain radiated to both arms and was<br />

associated with dyspnea, nausea, and vomiting. His only cardiac risk factor was a prior smoking<br />

history. He was taking an over-the-counter weight loss supplement for the past month.<br />

He was in no distress with a pulse of 50 and BP of 146/100; physical examination was otherwise<br />

normal. An electrocardiogram revealed an acute inferior-posterior myocardial infarction. During<br />

emergency cardiac catheterization a right coronary artery stent was placed. The patient did well and<br />

was discharged home three days later.<br />

Discussion: Obesity is an epidemic in the United States. The increasing number of overweight<br />

individuals has led to a growing market for fitness products and dietary supplements.<br />

Our patient was taking an over-the-counter weight loss supplement that may have played an<br />

important role in the development of his acute myocardial infarction. The ingredients listed were all<br />

natural ingredients. However, it was discovered that the product was taken off the market by the<br />

FDA because of an undeclared ingredient, didesmethyl sibutramine.<br />

The FDA is currently reviewing a study on sibutramine that shows it has minimal weight loss effect<br />

and based on the results of the Sibutramine Cardiovascular Outcome Trial (SCOUT) patients with<br />

cardiovascular disease had worse cardiovascular outcomes.<br />

This case reminds us that herbal medications and supplements may contain ingredients that can alter<br />

the normal physiology of the body and therefore, must be taken into consideration during a patient’s<br />

medical evaluation.<br />

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