Datasheet - Mirion Technologies

10/24/11 

Health Physicist monitors own medical dose 

from radioiodine thyroid ablation procedure 

California Campus RSO Meeting 

University of California, Irvine Medical Center 

October 24, 2011 

Sander Perle 

Dosimetry Services Division 

1

Mirion offers an array of solutions and services for managing radiological hazards. 

Learn more at: www.mirion.com 

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Agenda 

1. Present State of Passive Dosimetry 

2. Future State of Passive Dosimetry 

3 Direct Ion Storage (Instadose) Type Test Information 

4. I-131 thyroid study with instadose & TLD 

5. Future 

2 

Dosimetry Services 

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What dosimetry is appropriate for 

a specific monitoring requirement 

§ What is the purpose for wearing the dosimeter 

§ What are the key requirements 

§ How accurate and precise 

§ Ease of obtaining the dose data 

§ Timeliness of obtaining the data 

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§ Film 



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Minimum Reportable Dose is 

0.10 mSv 

Non-tissue Equivalent 

Energy Dependent 

Angular Dependent 

Requires Return processing 

Present state of passive dosimetry 

§ TLD 

§ Other Technologies have 

good features as well, but 

still require a processing 

facility to read and report 

doses to end users 

RPL 

OSL 

CR39 

Minimum Reportable Dose is 

0.01 mSv 

Tissue Equivalent 

Energy Independent 

Angular Independent 

Requires Return processing 


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Future State of Passive Dosimetry 

§ An accredited and approved remote read that does not 

require returning for processing and is electronically 

analyzed by trained staff that meets or exceeds technical 

requirements from customers and regulatory entities 


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Direct Ion Storage (DIS) Technology 

§ Instadose utilizes the DIS 

detector which stands for 

Direct Ion Storage 

§ DIS Dosimeter: 

§ Non Volatile Analog 

Memory Cell surrounded 

by a Gas Filled Ion 

Chamber 

§ For photon radiation, 

initial interactions take 

place in the wall material 

and secondary electrons 

ionize the gas of the 

chamber 


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DIS Detector Element 


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Direct Ion Storage Technology, 

Instadose, Read on a PC or Mac 

§ Instadose allows users to have the flexibility to view their radiation dose at any 

time from any computer with internet access. Readings via a PC or Mac are 

enabled by a USB compatible detector. 

§ When a user wishes to obtain a reading they simply log-in to their account, plugin 

instadose to a USB port and obtain their read. The accumulated dose stored 

on instadose is processed through a proprietary algorithm. Once complete a 

graphical representation of the current dose will load on the screen. Users can 

also view their cumulative dose level by clicking "View Cumulative Dose." 


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Technical Specs 

Minimum Reportable Dose (MRD) 0.01 mSv 

Lower Limit of Detection (LLD) 0.01 mSv 

Useful Dose Range 0.01 mSv – 5 Sv 

Energy Response Photon 5 keV – 6 MeV 

Accreditations/Approvals/Licenses NVLAP (100555), HSE, United 

Arab Emirates, Victoria and New 

South Wales, Australia, Nigeria 

9 


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2 

1.8 

1.6 

1.4 

1.2 

1 

0.8 

0.6 

0.4 

0.2 

0 



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Instadose Energy Response 

Instadose Energy Response 

NVLAP Proficiency Blind Test , ANSI N13.11-2009 

Energy (keV) 


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1.200 

1.150 

1.100 

1.050 

1.000 

0.950 

0.900 

0.850 

0.800 

0.750 



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Instadose Linearity 


1 10 100 1000 10000 100000 

Irradiated Dose (mRad) 



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2.00 

1.80 

1.60 

1.40 

1.20 

1.00 

0.80 

0.60 

-100 -50 0 50 100 

Degrees 



NS 30 (24 keV) 

0.60 

-100 -50 0 50 100 

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NS 80 (65 keV) 

1.40 

1.20 

1.00 

0.80 

Degrees 

Instadose Angularity 

Vertical 

Horizontal 

Vertical 

Horizontal 

NS 60 (48 keV) 

1.40 

1.20 

1.00 

0.80 

0.60 

-100 -50 0 50 100 

Degrees 

Vertical 

Horizontal 


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Low Dose Testing 


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§ Dose Rate Independent 



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Instadose Dose Rate Independent 


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§ 1.1 µSv/hr to 100 µSv/hr 

Response 

1.20 

1.10 

1.00 

0.90 

0.80 

0.70 

0.60 



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Low Dose Rate Test Data 

Low Dose Rate Test 

0 20 40 60 80 100 120 

Dose Rate (µSv/hour) 


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§ Two tests 



Temperature Testing 

§ Test 1 - 3 Groups (reference, +40C, -20C) were irradiated to 3 mSv 

§ Test 2 – 2 Groups (0.35 mSv and 0.05 mSv) at +40C 

Dose Value (mR) 

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350 

330 

310 

290 

270 

250 

Instadose Temperature Test 

299.3 301.7 299.2 

Reference Dose +40 C -20 C 

Group 

Dose Value (mR) 

40.0 

35.0 

30.0 

25.0 

20.0 

15.0 

10.0 

5.0 

0.0 

Instadose Low Dose 

Temperature Test 

36.9 36.0 

4.6 

Reference Dose 35 mR 5 mR 

Group 


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I-131 Radioiodine Thyroid Uptake Study 

§ August 29, 2011, radioiodine thyroid ablation procedure 

§ Administered 26.2 mCi (1 GBq) Sodium Iodide @9AM 

§ Instadose and TLD badges worn on lanyard (facing thyroid) 

§ Instadose on neck was read approximately every hour during daytime 

hours 

§ Instadose on neck was read prior to going to sleep, placed on window sill 

approximately 1 ft. from couch 

§ Instadose read first thing in the morning and the process described 

above was repeated 

§ After the first week the Instadose was read approximately 2 or 3 times a 

day 

§ Instadose and TLD badges strategically located throughout house to 

monitor doses 

§ TLDs were processed on September 8, 2011 

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Account: Sandy, Inc. (363) 

Location: Main 

EID Name 



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Report Run Time: 10/22/2011 8:38 AM 


HISTORY DETAIL REPORT 

Report Period: 08/29/2011 12:00 AM - 09/05/2011 12:00 AM 

Serial 

Number 

1 2 3 4 5 

6 7 8 

Accredited by the National Institute of Standards and Technology through NVLAP 

for the specific scope of accreditation under lab code 100555-0 

SEE LAST PAGE FOR COMPLETE REPORT DETAILS BY COLUMN NUMBER 

IT IS RECOMMENDED THAT YOU KEEP THIS REPORT FOR YOUR RECORDS 

P.O. BOX 16451 

IRVINE, CA 92623 

U.S./CANADA: 800.359.9686 

www.instadose.com 

Body 

Region 

Ship To: 

Read 

Date/Time 

113 Sienna Ridge 

Mission Viejo CA 92692 

United States 

Dose Reported in Units of mrem 

Deep 

(Whole Body) 

Number of Reads: 12 Total: 821 821 821 

Instadose, Two 74537 Torso 9/5/2011 8:33:00 PM 1 1 1 

74537 Torso 9/3/2011 2:28:00 PM 12 12 12 

74537 Torso 8/31/2011 7:43:00 PM * * * 

74537 Torso 8/31/2011 7:42:00 PM 3 3 3 

74537 Torso 8/31/2011 10:01:00 AM 18 18 18 

74537 Torso 8/30/2011 10:03:00 AM 30 30 30 

74537 Torso 8/29/2011 9:07:00 PM 50 50 50 

Number of Reads: 7 Total: 114 114 114 

Perle, Sandy 11801 Torso 9/5/2011 8:38:00 PM 66 66 66 

11801 Torso 9/5/2011 8:07:00 AM * * * 

11801 Torso 9/5/2011 8:05:00 AM 4 4 4 

11801 Torso 9/4/2011 8:57:00 PM 98 98 98 

11801 Torso 9/4/2011 9:12:00 AM * * * 

11801 Torso 9/3/2011 8:52:00 PM 64 64 64 

11801 Torso 9/3/2011 2:00:00 PM 63 63 63 

11801 Torso 9/3/2011 8:01:00 AM * * * 

11801 Torso 9/2/2011 9:20:00 PM 110 110 110 

11801 Torso 9/2/2011 1:01:00 PM 52 52 52 

Eye 


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Shallow 

(Skin) 

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ead date time mrem/h Read 

8/28/2011 17:50 0 2 

8/29/2011 9:58 3 56 

8/29/2011 11:05 139 156 

8/29/2011 12:02 157 149 

8/29/2011 13:02 133 133 

8/29/2011 14:01 153 150 

8/29/2011 15:02 139 141 

8/29/2011 16:00 133 129 

8/29/2011 17:03 122 129 

8/29/2011 18:00 96 91 

8/29/2011 19:00 94 94 

8/29/2011 20:03 99 104 

8/29/2011 21:02 90 88 

8/29/2011 22:13 98 116 

8/30/2011 6:54 

8/30/2011 7:57 96 101 

8/30/2011 9:00 105 111 

8/30/2011 10:01 

8/30/2011 11:09 97 109 

8/30/2011 12:00 79 68 

8/30/2011 13:16 64 80 

8/30/2011 15:51 142 

8/30/2011 19:03 136 

8/30/2011 21:53 58 163 



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read date time mrem/h Read 

8/31/2011 9:57 

8/31/2011 13:01 53 162 

8/31/2011 13:59 50 49 

8/31/2011 18:01 45 181 

8/31/2011 20:50 21 26 

8/31/2011 22:02 23 28 

9/1/2011 14:10 55 

9/1/2011 21:28 19 138 

9/2/2011 8:12 2 

9/2/2011 13:01 11 52 

9/2/2011 21:20 13 110 

9/3/2011 8:02 

9/3/2011 14:00 11 63 

9/3/2011 20:52 9 64 

9/4/2011 9:13 

9/4/2011 21:58 8 98 

9/5/2011 8:07 

9/5/2011 20:38 5 66 


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dose rate (mrem·hr -1 ) 

160 

140 

120 

100 

80 

60 

40 

20 

0 



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Instadose response on neck (lanyard) 


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Calculated uptake 

DRest = Γ·Aest·d -2 DRest = Γ·Aest·d -2 (e -‐μ x) 

ft ft cm (skin shielding) 

Date/ time elapse time Aest: (Aest = A0e -ʎeff∆t ) 1 0.25 1 

DRcalc Acalc = (DRcalc)(Γ·∙d -2 ) -1 Fraction 

8/28/2011 17:50 0.000 

8/29/2011 9:00 26.200 

8/29/2011 9:58 0.041 3 0.099 0.004 

8/29/2011 11:05 0.047 139 3.959 0.151 

8/29/2011 12:02 0.039 5.240 11.5 184.4 165.2 157 4.474 0.171 

8/29/2011 13:02 0.042 5.219 11.5 183.7 164.6 133 3.774 0.144 

8/29/2011 14:01 0.041 5.199 11.4 183.0 163.9 153 4.350 0.166 

8/29/2011 15:02 0.042 5.178 11.4 182.3 163.3 139 3.952 0.151 

8/29/2011 16:00 0.040 5.158 11.3 181.6 162.7 133 3.772 0.144 

8/29/2011 17:03 0.044 5.137 11.3 180.8 162.0 122 3.476 0.133 

8/29/2011 18:00 0.040 5.117 11.3 180.1 161.4 96 2.717 0.104 

8/29/2011 19:00 0.042 5.097 11.2 179.4 160.7 94 2.665 0.102 

8/29/2011 20:03 0.044 5.076 11.2 178.7 160.1 99 2.812 0.107 

8/29/2011 21:02 0.041 5.056 11.1 178.0 159.4 90 2.552 0.097 

8/29/2011 22:13 0.049 5.032 11.1 177.1 158.7 98 2.786 0.106 

8/30/2011 6:54 0.362 4.862 10.7 171.1 153.3 

8/30/2011 7:57 0.044 4.841 10.7 170.4 152.7 96 2.740 0.105 

8/30/2011 9:00 0.044 4.821 10.6 169.7 152.0 105 2.995 0.114 

8/30/2011 10:01 0.042 4.802 10.6 169.0 151.4 

8/30/2011 11:09 0.047 4.780 10.5 168.3 150.7 97 2.746 0.105 

8/30/2011 12:00 0.036 4.764 10.5 167.7 150.2 79 2.234 0.085 

8/30/2011 13:16 0.052 4.740 10.4 166.9 149.5 64 1.817 0.069 

8/30/2011 15:51 0.108 4.692 10.3 165.2 148.0 

8/30/2011 19:03 0.134 4.633 10.2 163.1 146.1 

8/30/2011 21:53 0.118 4.581 10.1 161.3 144.5 58 1.637 0.062 

8/31/2011 9:57 0.503 4.367 9.6 153.7 137.7 

8/31/2011 13:01 0.128 4.314 9.5 151.8 136.0 53 1.498 0.057 

8/31/2011 13:59 0.040 4.297 9.5 151.3 135.5 50 1.434 0.055 

8/31/2011 18:01 0.168 4.229 9.3 148.9 133.3 45 1.273 0.049 

8/31/2011 18:04 0.002 4.228 9.3 148.8 133.3 

8/31/2011 18:05 0.001 4.228 9.3 148.8 133.3 

8/31/2011 18:08 0.002 4.227 9.3 148.8 133.3 

8/31/2011 19:37 0.061 4.202 9.2 147.9 132.5 

8/31/2011 20:50 0.051 4.182 9.2 147.2 131.9 21 0.602 0.023 

8/31/2011 22:02 0.050 4.162 9.2 146.5 131.2 23 0.666 0.025 

9/1/2011 14:10 0.672 3.904 8.6 137.4 123.1 

9/1/2011 21:28 0.304 3.792 8.3 133.5 119.6 19 0.538 0.021 

9/2/2011 8:12 0.447 3.634 8.0 127.9 114.6 

9/2/2011 13:01 0.201 3.565 7.8 125.5 112.4 11 0.307 0.012 

9/2/2011 21:20 0.347 3.449 7.6 121.4 108.8 13 0.376 0.014 

9/3/2011 8:02 0.446 3.306 7.3 116.4 104.2 

9/3/2011 14:00 0.249 3.228 7.1 113.6 101.8 11 0.300 0.011 

9/3/2011 20:52 0.286 3.142 6.9 110.6 99.1 9 0.265 0.010 

9/4/2011 9:13 0.515 2.991 6.6 105.3 94.3 

9/4/2011 21:58 0.531 2.844 6.3 100.1 89.7 8 0.218 0.008 

9/5/2011 8:07 0.423 2.731 6.0 96.1 86.1 

9/5/2011 20:38 0.522 2.599 5.7 91.5 81.9 5 0.150 0.006 

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Loca&on 

Instadose vs. TLD results 

Instadose Reading 

(mSv) TLD Reading (mSv) 

Collar 35.15 30.25 

Computer Room #1 0.51 0.71 

Computer Room #2 0.47 0.6 

Window Sill #1 1.11 0.96 

Window Sill #2 1.11 0.83 

Spouse 0.05 0 


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Future? 


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10/24/11 

Questions? 


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Datasheet - Mirion Technologies

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