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Diseases of the Lung and Respiratory Tract Part

Diseases of the Lung and Respiratory Tract Part

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Tuberculosis<br />

• A.K.A. Consumption, commonest infectious COD in Operas<br />

– Mycobacteria tuberculosis<br />

– Mycobacteria bovis<br />

• <strong>Lung</strong> involvement is <strong>the</strong> major cause <strong>of</strong> morbidity/mortality<br />

– Rarely involves skin, oropharynx, lymphoid tissue<br />

– Pott’s disease (TB <strong>of</strong> spine)<br />

– Prosector’s wart (TB <strong>of</strong> h<strong>and</strong>)<br />

• Suppressed by cell mediated immunity, <strong>the</strong>refore<br />

– Cases increasing due to AIDS<br />

– There have been emergence <strong>of</strong> multiple-drug resistant strains<br />

– Impaired patients not completing a course <strong>of</strong> antibiotics<br />

• Treated with months <strong>of</strong> antibiotics (INH, Rifampin)<br />

• Streptomycin in <strong>the</strong> early days

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