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klini^ko ispituvawe na terapiskata efikasnost, podnoslivost i

klini^ko ispituvawe na terapiskata efikasnost, podnoslivost i

klini^ko ispituvawe na terapiskata efikasnost, podnoslivost i

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Clinical trial on terapeutic efficacy, tolerability and safety of peroral solutions Varumin 1 and 2 (Interevrogeneks)<br />

in a combined treatment with polyvitamin – antioxidative therapy in patients with biologicaly<br />

(PCR) detected HPV infection of high-risk type, with or without biopticaly verified CIN I<br />

A<strong>na</strong>lysis with Wilcoxon Matched Pairs Test did not present statistical significant differences<br />

between HPV PCR typization on the second and the third check-up among patients treated<br />

with placebo. (T = 7,00 Z = 0,733 p = 0,4630 ).<br />

4. CROSS ANALISYS BETWEEN GROUPS ACCORDING TO COLPOSCOPIC<br />

FINDINGS ON FIRST CHECK-UP<br />

Table 7. Distribution of patients according to colposcopic findings on first check up<br />

colposcopic findings investigated agent placebo<br />

A % A %<br />

normal findings ( 0 ) 13 28.26 12 28.57<br />

suspicious findings ( 1 ) 14 30.44 13 30.95<br />

abnormal findings ( 2 ) 19 41.30 17 40.48<br />

total 46 100 42 100<br />

Chart 7. Distribution of patients according to colposcopic findings on first check up<br />

20<br />

18<br />

16<br />

14<br />

12<br />

10<br />

8<br />

6<br />

4<br />

2<br />

0<br />

13<br />

14<br />

19<br />

University Gynecology and Obstetrics Clinic, Vodnjanska bb, University St. Cyrillus and Methodius, Skopje,<br />

Macedonia<br />

12<br />

13<br />

investigated agent placebo<br />

normal suspicious abnormal<br />

A<strong>na</strong>lysis with Mann-Whitney U Test did not present statistical significant differences according<br />

to colposcopic findings between groups on the first check-up. (Z = - 0,062 p = 0,950)<br />

17<br />

30

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