Reversible Cerebral Vasoconstriction Syndromes (RCVS)

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A B C (A) Headframe used for bedside TCD examination. Breath Holding Index %(V apnea-V baseline) V baseline x t apnea Normal = 1.2 ± 0.6 (B) Representative CT-angiogram showing multifocal segmental stenosis (“beading”) of the bilateral middle cerebral arteries, basilar, posterior cerebral, and superior cerebellar arteries. (C) TCD spectrum showing elevated mean flow velocity in the left MCA.
TCD response to Apnea (breath-hold) Percentage Change of CBFV (%) 20 15 10 5 0 -5 -10 -15 -20 Control Migraine <strong>RCVS</strong> BH start Min BH end
Page 1 and 2: Reversible Cerebral Vasoconstrictio
Page 3 and 4: Patients (mostly women): rTCH ± st
Page 5 and 6: Key Elements for Diagnosis 1. Sever
Page 7 and 8: Characteristic Clinical Features CC
Page 9: Laboratory and Imaging Features Cha
Page 12 and 13: Characteristic Follow-up Imaging CC
Page 14 and 15: RCVS: Brain Imaging
Page 16 and 17: Brain Hemorrhage in RCVS Hemorrhage
Page 18 and 19: • Migraine Differential Diagnosis
Page 20 and 21: Diagnostic Approach 1. Clinical Rec
Page 22 and 23: Characteristic Treatment and Outcom
Page 24 and 25: CTA before IA treatment (PPD 20) Si
Page 26 and 27: Final MRI 6 Days After Admission Si
Page 28 and 29: RCVS • Group of conditions charac
Page 31 and 32: Stroke attributed to ‘vasospasm
Page 36 and 37: Hemorrhages in 1 st week, Infarcts
Page 38 and 39: Pathophysiology
Page 42 and 43: Perivascular nerves smooth muscle c
Page 44 and 45: Endothelium • Modulates vascular
Page 46 and 47: Spectrum - disorders of cerebrovasc
Page 48 and 49: RCVS and Drugs/Meds Ergot derivativ
Page 50 and 51: Serotonin - central role in RCVS? S
Page 52 and 53: Serotonergic meds common…but RCVS
Page 54 and 55: RCVS and Migraine Is RCVS simply a
Page 56 and 57: Neurology 2006: 67:2164 • Prospec
Page 58 and 59: RCVS-SAH (n=35) vs. aSAH (n=515)
Page 60 and 61: RCVS vs. PACNS
Page 63 and 64: Angio positive in 70 cases; biopsy
Page 65 and 66: RCVS vs PACNS: MGH cases, 1993-2009
Page 67 and 68: RCVS vs PACNS: MGH cases, 1993-2009
Page 69 and 70: Brain lesion topography in RCVS 3.
Page 71 and 72: Lesion patterns in PACNS 2. Diffuse
Page 73 and 74: Distinguishing RCVS from PACNS Clin
Page 75 and 76: Advanced MRI for Cerebral Arteriopa
Page 77 and 78: To study the phenomena of disease w
Page 79 and 80: Illustrative Case 46 year male: acu
Page 81 and 82: Illustrative Case MR angio - severe
Page 84 and 85: PACNS - Typical Angiographic featur
Page 86: Treatment vs Poor Outcome All Patie

Reversible Cerebral Vasoconstriction Syndromes (RCVS)

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