VACCINES
VACCINES
VACCINES
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So-called naked DNA vaccines consist of DNA that is<br />
administered directly into the body. These vaccines can<br />
be administered with a needle and syringe or with a<br />
needle-less device that uses high-pressure gas to shoot<br />
microscopic gold particles coated with DNA directly into<br />
cells. Sometimes, the DNA is mixed with molecules that<br />
facilitate its uptake by the body’s cells. Naked DNA<br />
vaccines being tested in humans include those against the<br />
viruses that cause influenza and herpes as well as HIV.<br />
Recombinant Vector Vaccines<br />
Recombinant vector vaccines could be another possible<br />
strategy against bacterium X. These experimental<br />
vaccines are similar to DNA vaccines, but they use an<br />
attenuated virus or bacterium to introduce microbial<br />
DNA to cells of the body. Vector refers to the virus or<br />
bacterium used as the carrier.<br />
Harmless<br />
microbial shell<br />
Genes from diseasecausing<br />
microbe<br />
Recombinant vector vaccines use the harmless shell of one<br />
microbe to deliver genetic material of a disease-causing microbe.<br />
The genetic material contains the code for making vaccine antigen<br />
inside some of the body’s cells, using those cells as “factories.”