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Spina Bifida (myelodysplasia) - MDC Faculty Home Pages

Spina Bifida (myelodysplasia) - MDC Faculty Home Pages

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Etiology<br />

Poor maternal nutrition<br />

Radiation<br />

Research indicates that Folic Acid<br />

deficiency of mother is also indicated<br />

Pathophysiology<br />

Fusion failure of vertebral laminae of spinal<br />

column during the 4th week of gestation<br />

V Varying i d degree of f neurological l i l d deficits fi it<br />

present related to the portion of the spinal<br />

cord involved<br />

Pathophysiology<br />

The higher the defect, the greater the<br />

neurologic dysfunction<br />

B Below l 2nd 2 d lumbar l b vertebrae: t b partial ti l<br />

paralysis of lower extremity, varying degrees<br />

of sensory deficits, bowel and bladder<br />

disturbances<br />

5

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