The IX t h Makassed Medical Congress - American University of Beirut
The IX t h Makassed Medical Congress - American University of Beirut
The IX t h Makassed Medical Congress - American University of Beirut
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T h e I X t h M a k a s e d M e d i c a l C o n g r e s s<br />
ESOPHAGEAL AND GASTRIC LESIONS IN NEONATES<br />
NAHIDA RIFAI, MD<br />
<strong>The</strong> occurrence <strong>of</strong> severe lesions in the upper gastrointestinal tract in the neonatal period is<br />
relatively frequent. Upper gastrointestinal bleeding from mucosal lesions has been seen in 6 – 12<br />
% <strong>of</strong> children in intensive care.<br />
<strong>The</strong> precise etiology <strong>of</strong> such lesions is poorly substantiated. Any stressful event during pregnancy<br />
or labor or soon after birth may be inducive <strong>of</strong> mucosal lesions. Bleeding from the upper<br />
gastrointestinal tract can occur in the setting <strong>of</strong> hypotension, respiratory insufficiency, renal<br />
failure, sepsis, and in the presence <strong>of</strong> fetal distress. Antacids and anti-ulcer medications taken<br />
during pregnancy may play a role. Perinatal indomethacin exposure constitutes another<br />
additional risk factor.<br />
<strong>The</strong> technical improvement in pediatric gastrointestinal endoscopy allowed the evaluation <strong>of</strong><br />
esophageal and/or gastric lesions in neonates even in very low birth weight infants. <strong>The</strong> key <strong>of</strong><br />
prevention and treatment <strong>of</strong> stress-induced gastric lesions is the optimal intensive care. Breast<br />
feeding may play a protective role against severe lesions in neonates. Some <strong>of</strong> them may benefit<br />
from ulcer prophylaxis.<br />
CONGENITAL SHORT BOWEL SYNDROME: REPORT OF THREE CASES<br />
*Raphah Borghol MD, ‡Dany Hamod MD, §Reva Matta MD,<br />
†Pierre Mouawad MD, *Nabil Diab MD, ‡Elie Aramouni MD<br />
Congenital short bowel syndrome (CSBS) is a rare entity compared to the acquired form.<br />
We present three cases <strong>of</strong> CSBS manifested in the neonatal period by complicated severe<br />
necrotizing enterocolitis (NEC), and pseudoobstruction. <strong>The</strong> diagnosis was suspected by barium<br />
intestinal series swallow, and confirmed by surgical laparotomy. <strong>The</strong> management consists <strong>of</strong><br />
total parenteral nutrition (TPN), with one still living case and two fatal outcomes secondary to<br />
septicemia from the central catheter line, and multiorgan failure. In the literature, we note<br />
rare reported cases <strong>of</strong> such short congenital small bowel length. Normally the small bowel in<br />
neonates measures around 240 cm, in our cases the length were 30 cm, 58 cm, and 75 cm.<br />
<strong>The</strong> factors in the pathogenesis in these cases are mostly related to antenatal ischemic events,<br />
such as intrauterine volvulus, in utero infarction <strong>of</strong> bowel, defective neuroenteric system, and<br />
mechanical etiology such as delayed return <strong>of</strong> fetal gut into the abdomen due to gastroschisis.<br />
<strong>The</strong> management and prognosis depends mostly on the length <strong>of</strong> the small bowel and other<br />
factors related to the age <strong>of</strong> the patient, and their general status.<br />
*Pediatric resident (PGY-I), <strong>University</strong> Of Balamand, St Georges <strong>University</strong> Hospital<br />
‡Pediatric Neonatology, St Georges <strong>University</strong> Hospital<br />
§Pediatric Surgery resident (PGY-III), <strong>University</strong> Of Balamand, Saint Georges <strong>University</strong> Hospital<br />
†Pediatric Gastroenterology, Hepatology and Nutrition Unit, St Georges <strong>University</strong> Hospital<br />
*Pediatric Surgery, St Georges <strong>University</strong> Hospital<br />
‡Pediatric Gastroenterology, Chief <strong>of</strong> Departement, St Georges <strong>University</strong> Hospital.<br />
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