05.06.2013 Views

The IX t h Makassed Medical Congress - American University of Beirut

The IX t h Makassed Medical Congress - American University of Beirut

The IX t h Makassed Medical Congress - American University of Beirut

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

T h e I X t h M a k a s e d M e d i c a l C o n g r e s s<br />

ESOPHAGEAL AND GASTRIC LESIONS IN NEONATES<br />

NAHIDA RIFAI, MD<br />

<strong>The</strong> occurrence <strong>of</strong> severe lesions in the upper gastrointestinal tract in the neonatal period is<br />

relatively frequent. Upper gastrointestinal bleeding from mucosal lesions has been seen in 6 – 12<br />

% <strong>of</strong> children in intensive care.<br />

<strong>The</strong> precise etiology <strong>of</strong> such lesions is poorly substantiated. Any stressful event during pregnancy<br />

or labor or soon after birth may be inducive <strong>of</strong> mucosal lesions. Bleeding from the upper<br />

gastrointestinal tract can occur in the setting <strong>of</strong> hypotension, respiratory insufficiency, renal<br />

failure, sepsis, and in the presence <strong>of</strong> fetal distress. Antacids and anti-ulcer medications taken<br />

during pregnancy may play a role. Perinatal indomethacin exposure constitutes another<br />

additional risk factor.<br />

<strong>The</strong> technical improvement in pediatric gastrointestinal endoscopy allowed the evaluation <strong>of</strong><br />

esophageal and/or gastric lesions in neonates even in very low birth weight infants. <strong>The</strong> key <strong>of</strong><br />

prevention and treatment <strong>of</strong> stress-induced gastric lesions is the optimal intensive care. Breast<br />

feeding may play a protective role against severe lesions in neonates. Some <strong>of</strong> them may benefit<br />

from ulcer prophylaxis.<br />

CONGENITAL SHORT BOWEL SYNDROME: REPORT OF THREE CASES<br />

*Raphah Borghol MD, ‡Dany Hamod MD, §Reva Matta MD,<br />

†Pierre Mouawad MD, *Nabil Diab MD, ‡Elie Aramouni MD<br />

Congenital short bowel syndrome (CSBS) is a rare entity compared to the acquired form.<br />

We present three cases <strong>of</strong> CSBS manifested in the neonatal period by complicated severe<br />

necrotizing enterocolitis (NEC), and pseudoobstruction. <strong>The</strong> diagnosis was suspected by barium<br />

intestinal series swallow, and confirmed by surgical laparotomy. <strong>The</strong> management consists <strong>of</strong><br />

total parenteral nutrition (TPN), with one still living case and two fatal outcomes secondary to<br />

septicemia from the central catheter line, and multiorgan failure. In the literature, we note<br />

rare reported cases <strong>of</strong> such short congenital small bowel length. Normally the small bowel in<br />

neonates measures around 240 cm, in our cases the length were 30 cm, 58 cm, and 75 cm.<br />

<strong>The</strong> factors in the pathogenesis in these cases are mostly related to antenatal ischemic events,<br />

such as intrauterine volvulus, in utero infarction <strong>of</strong> bowel, defective neuroenteric system, and<br />

mechanical etiology such as delayed return <strong>of</strong> fetal gut into the abdomen due to gastroschisis.<br />

<strong>The</strong> management and prognosis depends mostly on the length <strong>of</strong> the small bowel and other<br />

factors related to the age <strong>of</strong> the patient, and their general status.<br />

*Pediatric resident (PGY-I), <strong>University</strong> Of Balamand, St Georges <strong>University</strong> Hospital<br />

‡Pediatric Neonatology, St Georges <strong>University</strong> Hospital<br />

§Pediatric Surgery resident (PGY-III), <strong>University</strong> Of Balamand, Saint Georges <strong>University</strong> Hospital<br />

†Pediatric Gastroenterology, Hepatology and Nutrition Unit, St Georges <strong>University</strong> Hospital<br />

*Pediatric Surgery, St Georges <strong>University</strong> Hospital<br />

‡Pediatric Gastroenterology, Chief <strong>of</strong> Departement, St Georges <strong>University</strong> Hospital.<br />

40

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!